scholarly journals Blood pressure and lipid profiles in adolescents with hypertensive parents

2016 ◽  
Vol 55 (6) ◽  
pp. 333
Author(s):  
Julia Fitriany ◽  
Rafita Ramayati ◽  
Supriatmo Supriatmo ◽  
Rusdidjas Rusdidjas ◽  
Oke Rina ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Total Cholesterol ◽  
Density Lipoprotein ◽  
Lipid Profiles ◽  
Cross Sectional ◽  
Parental History ◽  
Group I ◽  
History Of ◽  
Blood Pressures ◽  
Group Ii

problem of increasing prevalence and causes high morbidityand mortality. It is found primarily in young males, with afamilial history of hypertension and/or cardiovascular disease.Examination of lipid profiles has been used to detect the risk ofhypertension in adolescents.Objective To compare blood pressure and lipid profiles inadolescents with and without a parental history of hypertension.Methods This cross-sectional study was conducted from January toFebruary 2012 on students from a senior high school in the TobaSamosir District, North Sumatera. Sixty-eight adolescents wereincluded, aged 15 to 18 years. Group I comprised 34 adolescentswith hypertensive parents, and group II comprised 34 adolescentswith normotensive parents. Subjects were selected based onquestionnaires. Subjects’ blood pressures were measured at rest.Three measurements were made in intervals of 10-15 minutes,then averaged for both systolic and diastolic blood pressures. Lipidprofiles were measured using the CardioCheck cholesterol testafter subjects had fasted for 12 hours.Results The median systolic blood pressures (SBP) in groupsI and II were 110 mmHg (range 93.3-123.3) and 106.7 mmHg(range 96.7-123.3), respectively, (P=0.584). The median diastolicblood pressures (DBP) were 73.3 mmHg (range 66.7-83.3) and71.7 mmHg (range 63.3-80.0), respectively, (P=0.953). Totalcholesterol and low-density lipoprotein cholesterol (LDL-C) levelsin group I were significantly higher than those levels in group II[median total cholesterol: 162.0 (range 158-170) vs. 159.0 (range150-170), respectively; (P=0.001); and mean LDL-C: 103.5 (SD3.72) vs. 99.1 (SD 4.63), respectively; (P=0.001). Multivariateanalysis revealed a correlation of moderate strength betweenparental history of hypertension and increased LDL-C (P<0.001)in adolescents.Conclusion Adolescents with and without familial historyof hypertension have no significant median blood pressuredifferences. However, adolescents with hypertensive parents have afsignificantlyhigher median total cholesterol and mean LDL-C.Furthermore, we find a correlation between parental history ofhypertension and increased LDL-C in adolescents.

scholarly journals Normal Non-HDL Cholesterol, Low Total Cholesterol, and HDL Cholesterol Levels in Sickle Cell Disease Patients in the Steady State: A Case-Control Study of Tema Metropolis

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Richard K. D. Ephraim ◽  
Patrick Adu ◽  
Edem Ake ◽  
Hope Agbodzakey ◽  
Prince Adoba ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Steady State ◽  
Sickle Cell Disease ◽  
Total Cholesterol ◽  
Sickle Cell ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Lipoprotein Cholesterol ◽  
Cell Disease ◽  
Cross Sectional

Background.Abnormal lipid homeostasis in sickle cell disease (SCD) is characterized by defects in plasma and erythrocyte lipids and may increase the risk of cardiovascular disease. This study assessed the lipid profile and non-HDL cholesterol level of SCD patients.Methods.A hospital-based cross-sectional study was conducted in 50 SCD patients, in the steady state, aged 8–28 years, attending the SCD clinic, and 50 healthy volunteers between the ages of 8–38 years. Serum lipids were determined by enzymatic methods and non-HDL cholesterol calculated by this formula: non-HDL-C = TC-HDL-C.Results.Total cholesterol (TC) (p=0.001) and high-density lipoprotein cholesterol (HDL-C) (p<0.0001) were significantly decreased in cases compared to controls. The levels of non-HDL-C, low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) were similar among the participants. The levels of decrease in TC and HDL were associated with whether a patient was SCD-SS or SCD-SC. Systolic blood pressure and diastolic blood pressure were each significantly associated with increased VLDL [SBP,p=0.01, OR: 0.74 (CI: 0.6–0.93); DBP,p=0.023, OR: 1.45 (CI: 1.05–2.0)].Conclusion.Dyslipidemia is common among participants in this study. It was more pronounced in the SCD-SS than in SCD-SC. This dyslipidemia was associated with high VLDL as well as increased SBP and DBP.

scholarly journals TO STUDY THE ONSET AND PROGRESSION OF AIRWAY ABNORMALITY IN TERMS OF ALTERATION IN PFT IN ASYMPTOMATIC SMOKERS.

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Dr. Hitesh Kumar Solanki ◽  
Dr. Omnath P Yadav ◽  
Dr. Anita J Gojiya
Keyword(s):  
Lung Function ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Group I ◽  
Significant Difference ◽  
History Of ◽  
Young Smokers ◽  
The Mean ◽  
Group Ii

The study was conducted in department of physiology, B J Medical College, Ahmedabad from Mar. 2012 to Feb. 2013. This was a cross-sectional study to evaluate the effect of smoking on lung   function and serum lipids in asymptomatic smokers   and comparable non   smokers. The mean of the various spirometric parameters were calculated of the subjects for both the groups. The mean FVC in group I and group II was 2.60 ± 0.62 L and 4.10 ± 0.64L respectively. The mean FEV1 in group I was 1.91 ± 0.57L and     3.19 ± 0.77L in group II Group I had mean FEF25% - 75% and PEFR of 1.98 ± 0.67L/sec and 4.50 ± 1.57L/sec respectively. Group II had mean FEF25 – 75% of 4.22 ± 1.23L/sec and a mean PEFR of 7.22 ± 1.42L/sec. In young smokers and asymptomatic, still the spirometric values were significantly deranged as compared to controls. Even smokers with history of less pack years of smoking also had significant abnormalities of lung function. All he spirometric values in the two groups had statistically highly significant difference and were higher in non-smokers as compared to smokers. The spirometric values were reduced in smokers with history of smoking for as low as two pack years. Keywords: Progression, PFT, Asymptomatic & Smokers

scholarly journals Evaluation of lipid profiles and hematological parameters in hypertensive patients: Laboratory-based cross-sectional study

2018 ◽  
Vol 6 ◽  
pp. 205031211875666 ◽  
Author(s):  
Alemu Gebrie ◽  
Natesan Gnanasekaran ◽  
Menakath Menon ◽  
Mekonnen Sisay ◽  
Abriham Zegeye
Keyword(s):  
Blood Pressure ◽  
Blood Cell ◽  
Total Cholesterol ◽  
Hematological Parameters ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipid Profiles ◽  
Low Density ◽  
Blood Cell Count ◽  
Hypertensive Patients

Introduction: Hypertension and dyslipidemia are the two coexisting and synergizing major risk factors for cardiovascular diseases. The cellular constituents of blood affect the volume and viscosity of blood, thus playing a key role in regulating blood pressure. Overweight and obesity are key determinants of adverse metabolic changes including an increase in blood pressure. The aim of this study was to evaluate lipid profiles and hematological parameters in hypertensive patients at Debre Markos Referral Hospital, Northwest Ethiopia. Methods: Laboratory-based cross-sectional study was conducted in 100 eligible hypertensive patients at the hospital. The required amount of blood was withdrawn from the patients by healthcare professionals for immediate automated laboratory analyses. Data were collected on socio-demographic factors, anthropometric measurements, blood pressure, lipid profiles, and hematological parameters. Result: The mean serum levels of triglyceride, total cholesterol, and low-density lipoprotein were significantly higher than their respective cut-off values in the hypertensive patients. Besides, 54%, 52%, 35%, and 11% of the hypertensive patients had abnormal low-density lipoprotein, total cholesterol, triglyceride, and high-density lipoprotein levels, respectively. Higher levels of low-density lipoprotein, hemoglobin, and red blood cell count were observed in the hypertensive patients whose blood pressure had been poorly controlled than the controlled ones ( p < 0.05). Waist circumference had a significant positive association with the serum levels of total cholesterol and white blood cell count ( p < 0.05). Conclusion: Hypertensive patients had a high prevalence of lipid profile abnormalities and poorly controlled blood pressure which synergize in accelerating other cardiovascular diseases. Some hematological parameters such as red blood cell count are also increased as do the severity of hypertension.

scholarly journals Lipid profiles in smoking and non-smoking male adolescents

2014 ◽  
Vol 54 (4) ◽  
pp. 232
Author(s):  
Sigit Prastyanto ◽  
Mei Neni Sitaresmi ◽  
Madarina Julia
Keyword(s):  
Total Cholesterol ◽  
Tobacco Smoking ◽  
Ldl Cholesterol ◽  
Smoking Status ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Lipid Profiles ◽  
Cross Sectional ◽  
Mean Differences

Background The prevalence of smoking in adolescentstends to increase. Smoking is associated with a higher risk ofdyslipidemia.Objective To compare the lipid profiles of tobacco-smoking andnon-tobacco-smoking male adolescents.Methods We performed a cross- sectional study in three vocationalhigh schools in Yogyakarta from January to April 2011. Dataon smoking status, duration of smoking and number cigarettesconsumed per day were collected by questionnaires. We randomlyselected 50 male smokers and 50 male non-smokers as the studysubjects.Results Mean differences between smokers and non-smokerswere 44.5 (95%CI 28. 7 to 60.1) mg/dL for triglyceride levels; 8.0(95% CI 1.0 to 14.9) mg/dL for low density lipoprotein (LDL)cholesterol; 11.8 (1.1 to 22.4) mg/dL for total cholesterol and -5.7mg/dL (95% CI -8.8 to -2.6) for high density lipoprotein (HDL)cholesterol. Mean differences (95% CI) between smokers whohad engaged in smoking for > 2 years and those who had smokedfor :S:2 years were -18.1 (95% CI -33 .9 to -2.3) mg/dL for totalcholesterol; -49.4 (95% CI -67.2 to -3 1.5) mg/dL for triglycerides.Mean differences between those who smoked > 5 cigarettes/dayand :s:5 cigarettes per day were -18 .4 (95% CI -32.8 to -4.1) mg/dL for total cholesterol and -29.1 (95% CI -53.6 to -4.6) mg/dLfor triglycerides.Conclusion Smoking more than 5 cigarettes/day significantlyincreases total cholesterol, LDL cholesterol, and triglyceridelevels, as well as reduces HDL cholesterol levels; while smokingmore than 2 years significantly increases total cholesterol andtriglyceride levels

Attenuation of Cardiovascular Response During Laryngoscopy and Endotracheal Intubation by Using Pethidine with Lignocaine

1970 ◽  
Vol 6 (2) ◽  
pp. 40-43 ◽  
Author(s):  
MT Mollick ◽  
MD Hossain ◽  
NP Ali
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Body Weight ◽  
General Anaesthesia ◽  
Endotracheal Intubation ◽  
Cardiovascular Response ◽  
Rate Pressure Product ◽  
Group I ◽  
Blood Pressures ◽  
Group Ii

A prospective comparative study was done on lignocaine versus lignocaine with pethidine to observe the effect on cardiovascular response to laryngoscopy and endotracheal intubation. One hundred such elective surgical patients of active age group (16 - 60 years) having American Society of Anaesthesiologist (ASA) physical status I & II irrespective of surgical procedure were randomly assigned to one of the two groups of 50 each. Group I received injection lignocaine 1 mg/kg intravenously 02 minutes before induction of general anaesthesia. Patients in group II received injection pethidine 1 mg/kg body weight and injection lignocaine 1 mg/kg body weight intravenously 02 minutes before induction of general anaesthesia. Haemodynamic parameter i.e. blood pressures (systolic blood pressure, diastolic blood pressure and mean blood pressure), heart rate, rate pressure product were monitored after 1st, 3rd, 5th minutes following intubation. There were statistically significant (p<0.001) increase in blood pressures, heart rate and rate pressure product in group I i.e. pretreatment with 1 mg/kg body weight intravenous lignocaine and remained so after 5 minutes. On the other hand there were no statistically significant (p>0.05) increase in heart rate, blood pressures and rate pressure product in group II, where pretreatment done with pethidine 1 mg/kg body weight with lignocaine 1 mg/kg body weight and the values returned control level before 5 minutes. The study showed that pethidine 1 mg/kg body weight with lignocaine 1 mg/kg body weight pretreatment suppresses the cardiovascular response due to laryngoscopy and intubation. Key words: Cardiovascular response; laryngoscopy; lignocaine with pethidine. DOI: 10.3329/jafmc.v6i2.7274JAFMC Bangladesh. Vol 6, No 2 (December) 2010 pp.40-43

scholarly journals The Effect of Consuming Mineral Water and Piped Water on Blood Pressure and Lipid Profiles of Hypertensive Men

2019 ◽  
Author(s):  
Akram Kooshki ◽  
Mahmood Rivandi ◽  
Mohammad Reza Behroozikhah ◽  
Roya Akbarzadeh
Keyword(s):  
Blood Pressure ◽  
Total Cholesterol ◽  
Mineral Water ◽  
Density Lipoprotein ◽  
Serum Triglyceride ◽  
Lipid Profiles ◽  
Lipoprotein Cholesterol ◽  
Total Hardness ◽  
Piped Water ◽  
The Mean

Background: Hypertension is the third risk factor for the cardiovascular diseases. This study investigated the effects of mineral water from Damavand spring on the blood pressure and serum lipid profiles in men with hypertension. Methods: In this study 41 hypertensive men were randomly assigned to Damavand mineral water (DM) and Tehran water groups (TW). The DM and TW received 1.5-liter bottle of mineral water of Damavand spring and Tehran piped water bottled, respectively. The participants' blood pressure, serum triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDLc), and high-density lipoprotein cholesterol (HDLc) were measured at the beginning and end of the study. Total hardness of water was measured by titration with EDTA. Results: The results showed that the mean systolic and diastolic blood pressures decreased in both groups at the end of the study compared to the baseline (P < 0.05), but the difference was not significant. Serum TC and LDLc significantly in the case group at the end of week 8 compared to the baseline (P < 0.05) and this reduction was significant (P < 0.05). Moreover, no significant differences were observed between the two groups with regard to the mean changes of TG and HDLc (P > 0.05). Conclusions: The findings showed that the daily consumption of 1.5 liters of premium mineral water of Damavand springs decreased the systolic and diastolic blood pressure, total cholesterol, and LDLc levels.

scholarly journals A study of lipid profile in subclinical hypothyroidism in tertiary care hospital, Kolkata, India

2020 ◽  
Vol 7 (5) ◽  
pp. 760
Author(s):  
Kaushik Saha ◽  
Dipa Saha
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Subclinical Hypothyroidism ◽  
Ldl Cholesterol ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Care Hospital ◽  
Group I ◽  
Group Ii

Background: Objective was to study lipid profile in patients of subclinical hypothyroidism in tertiary centre in Kolkata, West Bengal and compare the same with matched controls.Methods: This observational study (single exposure) was conducted May 2019 to Nov 2019 at Department of Medicine, KPC Medical College, Jadavpur, Kolkata in subjects diagnosed with Sub Clinical Hypothyroidism [defined as normal T3 or FT3, normal T4 or FT4, and with increased TSH. Sixty patients with subclinical hypothyroidism were selected after careful exclusion; lipid profile was compared with matched controls.Results: Between the two groups (group I - controls vs. group II - cases), the values were as follows: Mean serum total T3 value was 114.03±29.22 ng/dl vs. 106.15±36.24 ng/dl (p = 0.3476); mean total T4 was 7.07±1.69 μg/dl vs. 6.86±1.31 μg/dl (p = 0.535); mean TSH was 3.17±1.28 μIU/ml vs. 9.77±4.19 μIU/ml (p <0.0001). Lipid profile pattern (group I vs. group II) was as follows: Mean total cholesterol (TC) 125.50±9.18 mg/dl vs. 162.07±42.32 mg/dl (p <0.0001), mean triglycerides (TG) is 136.65±14.82 mg/dl vs. 148.90±65.27 mg/dl (p = 0.3236), low-density lipoprotein (LDL)-cholesterol is 62.17±7.40 mg/dl vs. 98.81±33.26 mg/dl (p <0.0001), high-density lipoprotein (HDL)-cholesterol 39.17±6.62 mg/dl vs. 34.27±9.63 mg/dl (p = 0.0702), very low-density lipoprotein (VLDL) levels are 34.54±15.38 mg/dl vs. 32.08±13.21 mg/dl (p = 0.5245)..Conclusions: Subclinical hypothyroidism is associated with increased serum total cholesterol and LDL-Cholesterol levels. Therefore, there is a potential association between Subclinical hypothyroidism and atherosclerosis.

scholarly journals Mortalite A La Phase Aiguë De L’avc Hemorragique Sous Notre Protocole De Baisse De La Tension Arterielle A l’Hopital Universitaire (HU) Befelatanana Antananarivo

2018 ◽  
Vol 14 (18) ◽  
pp. 325
Author(s):  
Rajaonarison Lala Andriamasinavalona ◽  
Rasaholiarison Nomena Finiavana ◽  
Razafindrasata Ratsitohara Santatra ◽  
Razafimahefa Julien ◽  
Zodaly Noël ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Mortality Rate ◽  
Hospital Mortality ◽  
High Blood Pressure ◽  
Acute Phase ◽  
Hemorrhagic Stroke ◽  
University Hospital ◽  
Cross Sectional ◽  
Group I ◽  
Group Ii

Introduction: Hemorrhagic stroke can be seen in 90% of cases with high blood pressure. It is a predictor of intra-hospital mortality. Our goal is to compare the mortality rate based on admission under our therapeutic strategy for HTA in the acute phase of stroke. Method: A retrospective descriptive, cross-sectional study of consecutive patients was conducted over a 12-month period during the year 2017. Results: We had 20% (3/15) mortality rate in acute phase in those with systolic blood pressure (SBP) in admission at ≥ 180 mmHg (group II) and no death (0/17) was recorded in the those with SBP in admission at 140-179mmHg (group I). A SBP at the 7th day (D7) less than 140 mmHg was not rich in those two groups: 35.29 % in group I (n=6) and 46.66 % in group II (n=7) respectively. The sex ratio was 1. High blood pressure remains the main cardio-vascular risk factor reported in our study (81.21%). All our patients had Glasgow scale value between 13-15 and only the NIHSS value > 10 was associated with high blood pressure in acute phase (p=0.0131). Brain CT Scan was realised in majority of cases at the second day (D2) of stroke (n=16). This, however, is with localisation preference in the basal ganglia, with intra-cerebral hemmorhage (ICH) scale at 1 in 65.62% (n=21) of cases. Conclusion: Intra-hospital mortality in acute phase of hemorrhagic stroke remains high. Instauration of stroke field in Madagascar is necessary and this gives the Befelatanana University Hospital a Neuro- Vascular Intensive Care Unit too.

scholarly journals The role of blood pressures in patients with a headache

2016 ◽  
Vol 5 (2) ◽  
Author(s):  
Mehrdokht Mazdeh ◽  
Mojtaba Khazaei ◽  
Arezou Sayad ◽  
Javad Zebarjadi Bagherpour ◽  
Mohammad Taheri
Keyword(s):  
Blood Pressure ◽  
Cross Sectional Study ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
History Of ◽  
Daily Headache ◽  
Blood Pressures ◽  
Stage 1

Background: A headache is the most common cause of patients referred to the doctor. About 40 percent of people are suffering from a headache for at least once a year. Due to it's the high prevalence and its association with cardiovascular diseases, hypertension was considered as a  health problem in industrialized and developing countries. The aim of this study was to investigate the role of blood pressure in patients with a headache referred to the neurological clinic during  2014-2015 in Hamadan.Method: This cross-sectional study was performed to evaluate patients with a headache referred to the neurological clinic. Exclusion criteria included: a headache with a specific cause (a migraine, stroke, chronic daily headache, kidney disease, Diabetes Mellitus, history of heart disease or use of cigarette. The data were entered into the list and then were analyzed by SPSS software through paired T-test and chi-square test.Results: In this study, the 100 patients with a headache (78% females and 22% males) were investigated. The average age of patients was 60.07±13.175 years. The prevalence of stage 1 & 2 hypertension was 85%, and prehypertension prevalence of 7% was reported. Most of the headaches were in the frontal (33 %). Furthermore, the most headaches occur in varied time (70%). There wasn’t a significant correlation between age (P-value=0.698), gender (P-value=0.952), headache and blood pressure.Conclusion: The results obtained from the present study indicated that there was not any significant correlation between a headache and blood pressure, and the prevalence of blood pressure in the patients with a headache was similar to those who do not have headaches.Keywords: Blood Pressure, Hypertension, Headache

scholarly journals Study of anthropometric indices and it’s co-relation with blood pressure in young healthy individuals

2018 ◽  
Vol 5 (5) ◽  
pp. 2003
Author(s):  
Sano Maleth Zachariah ◽  
Swati Manikrao Mahajan ◽  
Rajesh Keshavrao Dase
Keyword(s):  
Blood Pressure ◽  
Family History ◽  
Epidemiological Studies ◽  
Overweight And Obesity ◽  
Neck Circumference ◽  
Anthropometric Indices ◽  
Cross Sectional ◽  
Parental History ◽  
History Of ◽  
Family History Of Hypertension

Background: Overweight and obesity are shown to be independent risk factors for hypertension by several epidemiological studies. A practical, inexpensive and easily performed method for evaluation of body fat is anthropometry. Hence the present study was undertaken to explore association between anthropometric indices and blood pressure and determine efficacy of neck circumference to identify overweight subjects and define NC cutoff levels for overweight and obesity.Methods: Cross sectional, comparative study conducted on apparently healthy medical college students, 150 having parental history of hypertension and 150 without a parental history of hypertension. Height, weight, waist circumference, hip circumference, neck circumference, body mass index, waist-hip ratio, waist- height ratio, and blood pressure were measured. Data was analyzed using SPSS version 20.Results: Prevalence of pre-hypertension is 42.33%. 54.33% pre-hypertensive subjects had family history of hypertension but there is no statistically significant association between family history of hypertension and pre-hypertension. Neck circumference correlated with BMI, WC, W/H ratio (p<0.05) indicating that NC could be a useful screening tool. NC cutoff values determining overweight & obesity in this study is >33.30 cm in females and >37.15 cm in males. 61.76% and 38.98% pre-hypertensive males and females respectively have BMI above 25Kg/m² in comparison to 19.51% normotensive males and 20.88% normotensive females.Conclusions: Study reveals development of hypertension is attributable to overweight and obesity and no statistically significant relationship has been established between family history of hypertension and risk for developing hypertension. NC>37.15cm for males and >33.30 cm for females was the best cut off levels for determining overweight/obese subjects.

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