scholarly journals TRITERPENE COMPOUNDS OF THE ABOVE GROUND ORGANS OF THE BUPLEURUM SCORZONERIFOLIUM WILLD. OF THE BAIKAL REGION FLORA

2019 ◽  
pp. 215-222
Author(s):  
Svetlana Andreyevna Petukhova ◽  
Daniil Nikolayevich Olennikov ◽  
Vera Mikhaylovna Mirovich
Keyword(s):  
Biologically Active ◽  
Cytostatic Effect ◽  
Flowering Phase ◽  
Quantitative Content ◽  
Irkutsk Region ◽  
Bupleurum Scorzonerifolium Willd ◽  
Bupleurum Scorzonerifolium ◽  
First Time ◽  
Derivatives Of ◽  
Active Substances

Representatives of the genus Bupleurum L. in the composition of biologically active substances accumulate triterpene compounds (derivatives of α-amyrin and β-amyrin). Triterpene glycosides isolated from plants of the genus Bupleurum are called saikosaponinov, buplevrozidy, skorzonerozidy. Plants of the genus Bupleurum in the underground organs accumulate triterpene compounds in an amount of from 1 to 7%. Triterpene compounds of plants of the genus Bupleurum possess a hepatoprotective, antiviral, cytostatic effect. We have studied the triterpene compounds of the aerial organs of Bupleurum scorzonerifolium Willd. The material for the study was collected on the territory of the Irkutsk region (Russia). Isolation of triterpene compounds was performed with 70% ethyl alcohol. The compounds were identified by liquid chromatography with mass spectrometry and diode-matrix detection (UPLC-DAD-ESI-MS/MS). According to the results of the analysis, the content of 5 triterpene compounds was established: saikosaponinov A, B2, C, D, F. The isolated compounds are structurally derived from oleanan, in which glycosidation is observed at the C-3 position with α-L-rhinose, β-D-glucose and β-D-fucose. The spectrophotometric method determined the quantitative content of the amount of triterpene compounds in the above-ground organs of B. scorzonerifolium at different phases of the vegetation of the plant, by organs (in flowers, leaves, stalks), and also depending on the place of growth. It has been established that the maximum amount of the amount of triterpene compounds accumulates in the aboveground organs of B. scorzonerifolium during the flowering phase – 1.54±0.05%; the highest content of this group of compounds is noted in flowers – 1.70±0.06%; most of all, this group of compounds is collected by samples collected in the Ust-Horde Buryat District (1.96±0.06%). The aboveground organs of B. scorzonerifolium can be used as a source of triterpene compounds, the highest content of which is noted in the flowering phase. The study of triterpene compounds in the aboveground organs of B. scorzonerifolium was carried out for the first time.

scholarly journals A COMPARATIVE STUDY OF THE ELEMENTAL COMPOSITION AND BIOLOGICALLY ACTIVE SUBSTANCES OF PLANTS OF THE GENUS SAUSSUREA DC. FLORA OF EASTERN SIBERIA

2018 ◽  
pp. 205-214 ◽  
Author(s):  
Ярослав (Yaroslav) Евгеньевич (Evgen'yevich) Решетов (Reshetov) ◽  
Михаил (Mikhail) Валерьевич (Valer'yevich) Белоусов (Belousov) ◽  
Елена (Elena) Юрьевна (Yur'yevna) Авдеева (Avdeeva) ◽  
Маргарита (Margarita) Николаевна (Nikolayevna) Шурупова (Shurupova)
Keyword(s):  
Inductively Coupled Plasma ◽  
Pharmaceutical Research ◽  
Hydroxycinnamic Acids ◽  
Water Soluble ◽  
Biologically Active ◽  
Eastern Siberia ◽  
Inductively Coupled ◽  
Quantitative Content ◽  
First Time ◽  
Active Substances

A method of mass spectrometry with inductively coupled plasma determine the content of essential, conditionally essential and toxic elements in 7 plants of the genus Saussurea (saussurea): S. small-flowered (S. parviflora (Poir.) DC.), S. latifolia (S. latifolia Ledeb.), S. amara (S. amara (L.) DC.), S. frolovii (S. frolowii Ledeb.), S. daurica (S. daurica Adams.), S. salicifolia (S. salicifolia (L.) DC.) and S. controversa (S. contrоversa DC.). For the first time the representatives of the genus saussurea, accumulating a significant amount of calcium - S. salicifolia, S. controversa, S. frolowii (42357, 41376 and 23818 mg/kg, respectively) correlates with the content of water-soluble polysaccharides. The predominant amount of magnesium is determined in S. daurica, S. controversa and S. amara (7183, 2826 and 1927 mg/kg), phosphorus – in S. frolowii, S. controversa and S. parviflora (1740, 1378 and 1117 mg/kg), vanadium – in S. salicifolia and S. controversa (1.2 and 1.1 mg/kg). Selenium in the amount of 0.8 mg / kg was found in S. daurica. The quantitative content of the main fractions of polysaccharide complexes, flavonoids, hydroxycinnamic acids of these species was established. The highest content of flavonoids and hydroxycinnamic acids is found in the aboveground organs S. controversa, S. latifolia, and S. daurica, S. controversa species, which contains the maximum number of fractions of water-soluble polysaccharides, phenolic compounds and bioelements, is a promising object for further pharmaceutical research.

scholarly journals DYNAMIC CHANGES IN THE COMPOSITION OF BIOLOGICALLY ACTIVE COMPOUNDS OF BUPLEURUM SCORZONERIFOLIUM WILLD. AERIAL PART IN DIFFERENT PHENOLOGICAL PHASES

2020 ◽  
pp. 111-118
Author(s):  
Zhargal Aleksandrovich Tykheev ◽  
Vasiliy Vladimirovich Taraskin ◽  
Svetlana Vasilyevna Zhigzhitzhapova ◽  
Daba Gombocyrenovich Chimitov ◽  
Larisa Dorzhievna Radnaeva
Keyword(s):  
Phenolic Compounds ◽  
Essential Oils ◽  
Aerial Part ◽  
Lipid Fraction ◽  
Total Content ◽  
Biologically Active ◽  
Flowering Phase ◽  
Bupleurum Scorzonerifolium Willd ◽  
Bupleurum Scorzonerifolium ◽  
Phenological Phases

The article is devoted to investigate the changes in the composition of biologically active substances (essential oils, lipid fraction, phenolic compounds) of the aerial part of the Bupleurum scorzonerifolium Willd. in depending on the phase of plant development. The greatest variety of compounds included in the composition of essential oils is characterized by a flowering phase. Fifteen terpene compounds – p-cymol, β-myrcene, trans-β-ocymene, limonene, (E,E)-α-farnesene, α-copaene, β-elemene, humulene, germacrene D, caryophyllene, γ-muurolene, bicyclogermacrene, Δ-cadinene, t-muurolol, spatulenol – are constant components of essential oils, regardless of phenophase. The quantitative content of these components varies from trace to major at different phenological phases. The coincidence of the main components of the lipid fraction was established. The main saturated acid is 16:0. Its content changes depending on the phase of vegetation – it is approximately at the same level determined in the phases of vegetation and flowering phases (26.78% and 27.26%, respectively) and there is a decrease in the fruit phase (18.17%). The main monounsaturated fatty acid is 18:1n9. Its greatest content was found in the fruiting phase, the smallest – flowering. The predominant polyunsaturated fatty acid is 18:2n9,12. Its greatest content was found in the vegetation phase (26.78%), the lowest - flowering (24.23%). However, the total content of unsaturated fatty acids exceeds the total content of saturated fatty acids in all phases of plant development. Although, their ratio varies from phenophase. There is a general pattern of highest content of phenolic compounds in the flowering phase for all studied samples. It was shown that during the flowering phase, the maximum accumulation of essential oils, lipids and phenolic compounds is observed.

scholarly journals BIOLOGICALLY ACTIVE SUBSTANCES OF THE HERB OF URTICA DIOICA

2006 ◽  
Vol 14 (1) ◽  
pp. 25
Author(s):  
V. Ya. Yatziuk ◽  
G. A. Chaly ◽  
O. V. Soshnikova
Keyword(s):  
Total Content ◽  
Urtica Dioica ◽  
Water Soluble ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Raw Material ◽  
Quantitative Content ◽  
Phenol Composition ◽  
First Time ◽  
Active Substances

We have established the qualitative composition and the quantitative content of biologically active substances of the herb of Urtica dioica. Aminoacid composition, monosaccharide set of PSK and PV, the presence of 4 macro- and 18 microelements and their quantitative content have been studied for the first time. Investigating the phenol composition of the herb of Urtica dioica by HPLC has revealed in the raw material alongside with the previously described gallic, coffeic acids, rutine and quercetine the presence of hyperoside, luteolin-7-glycoside, 3,4-isoramnetin diglycoside, chlorogenic acid, aesculetin. We were the first to determine the total content of water-soluble polysaccharides, pectin substances, astringent substances, pigments (carotenoids and chlorophylls),vitamin K1, triterpene compounds and saponins of the triterpene type.

scholarly journals Відходи вирощування представників роду ехінацея (Echinacea Moench) як перспективне джерело біологічно активних речовин

2013 ◽  
pp. 136-141
Author(s):  
С. В. Шершова
Keyword(s):  
Aqueous Solution ◽  
Waste Product ◽  
Echinacea Purpurea ◽  
Biologically Active ◽  
Purple Coneflower ◽  
Echinacea Pallida ◽  
Specific Proteins ◽  
Effective Use ◽  
First Time ◽  
Active Substances

Проведено експериментальне обґрунтування біо-конверсії відходів вирощування (полови) ехінацеїпурпурової (Echinacea purpurea (L.) Moench.) таехінацеї блідої (Echinacea pallida (Nutt) Nutt.).Доведена висока активність екстрактів полови зехінацеї пурпурової, що проявлялася у стимуляціїросту тест-культури. Встановлено, що найвищустимулюючу активність мають екстракти поло-ви ехінацеї пурпурової: водні за концентрації0,01 %, спиртові – 0,01–0,001 %; до того ж іззбільшенням концентрації спирту в екстрактахзнижувалась їх активність. Вперше встановлено,що полова ехінацеї містить специфічні білки –лектини, активність яких у відходах ехінацеї блі-дої значно перевищувала ехінацею пурпурову. Роз-роблено технологічні схеми отримання лектинівта екстрактів біологічно активних речовин із від-ходів вирощування (полови) для їх ефективноговикористовування. The experimental foundation bioconversion of waste product of growing (chaff), purple coneflower(Echinacea purpurea (L.) Moench.) and pale coneflower (Echinacea pallida (Nutt.) Nutt.) was to carriedout. The high activity of extracts of coneflower chaff, which had growth-stimulating effect to the testculture, was proved. Found that the highest stimulating activity has the extract of chaff purpleconeflowers: aqueous solution at concentrations of 0.01 %, alcohol-0.01 %-0.001 % and with increasingconcentration of alcohol in the extracts decreased their activity. For the first time it has been shown thatchaff of Echinacea contains specific proteins - lectins, and their activity in the waste product of paleconeflower significantly exceeded then activity in the waste product of purple coneflower. Technologicalschemes to get of lectins and extracts of biologically active substances from waste growing product(chaff), was worked out for their effective use.

scholarly journals Flowers of Campanula species as a source of biologically active substances

2021 ◽  
Vol 38 ◽  
pp. 00033
Author(s):  
Tatiana Fomina ◽  
Tatiana Kukushkina
Keyword(s):  
Ascorbic Acid ◽  
Western Siberia ◽  
Food Additives ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Raw Material ◽  
Forest Steppe ◽  
Wet Weight ◽  
First Time ◽  
Active Substances

The content of the major groups of biologically active substances in flowers of 7 Campanula species, cultivated in the forest-steppe of Western Siberia, were investigated for the first time. Freshly collected flowers were found to contain 0.06-0.15 % of catechins, 0.31-3.17 % of flavonols, 3.31-6.47 % of tannins, 3.10-15.57 % of pectic substances, and 0.66-16.4 mg% of carotenoids calculated per absolute dre weight of raw material. The amount of ascorbic acid was 36.9-114.0 mg% per wet weight. The data indicate that Campanula flowers are promising for the production of phenolic compounds, the development of food additives and fresh consumptions a seasoning.

FULLERENECARBOXYLIC ACIDS AND PROSPECTS FOR THEIR USE IN THE CHEMISTRY OF DRUGS

2018 ◽  
Vol 18 (2) ◽  
pp. 19-28
Author(s):  
E V Litasova ◽  
L B Piotrovskiy
Keyword(s):  
Delivery Systems ◽  
Water Soluble ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Carboxyl Groups ◽  
Derivatives Of ◽  
Active Substances

Among the various derivatives of fullerenes, compounds containing carboxyl groups (carboxyfullerenes) occupy a prominent place. The reason is that the introduction of carboxyl groups makes it possible to obtain water-soluble derivatives of highly lipophilic fullerenes. The review deals with matters of synthesis and structure of carboxyfullerenes, the influence of the amount and structure of the addends on the solubility of the entire compound, various aspects of the usage of these compounds as independent biologically active substances and carriers for creation of various delivery systems.

scholarly journals Valorization of Lavender Waste – Obtaining and Characteristics of Polyphenol Rich Extracts

2018 ◽  
Vol 1 (1) ◽  
pp. 11 ◽  
Author(s):  
Kostadinka B. Karneva ◽  
Ivelina N. Vasileva ◽  
Petko N. Denev ◽  
Rositsa S. Denkova ◽  
Vasil T. Shikov ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Capacity ◽  
Dry Matter ◽  
Biologically Active ◽  
Total Flavonoids ◽  
Linalyl Acetate ◽  
Lower Quantity ◽  
Promising Source ◽  
First Time ◽  
Active Substances

Bulgaria became the leading producer of lavender oil in the last years. Due to the lower quantity of essential oil large amounts of waste were generated which distilleries usually discard, although the residues are rich source of biologically active substances. The objective of this study was to obtain polyphenol-rich extracts from lavender waste and to investigate their chemical composition and antioxidant capacity. Two wastes (Mirkovo, Bulgaria, 2016) were investigated – steam distilled (SD-L) and CO2-extracted lavender (CO2-L). The major aroma constituents found were linalool and linalyl acetate – 30.68% and 25.82%, respectively, and the highest concentrations were found in the SD-L. The total flavonoids in CO2-L and SD-L were 2.91±0.11 and 3.72±0.20 mg/g dry matter residue, respectively. The higher amount of phenolic acids was observed in the SD-L waste – 2.62±0.19 mg/g, compared to 1.39±0.14 mg/g dry matter residue for CO2 extracted lavender. The antioxidant activity of the extracts was investigated by DPPH (SD-L – 355.48±23.12 µmol TE/g DW waste; CO2-L – 283.21±17.04 µmol TE/g DW waste) and FRAP (SD-L – 427.36±26.54 µmol TE/g DW waste; CO2-L – 311.29±18.17 µmol TE/g DW waste). Both methods suggested that SD-L residue had higher antioxidant capacity and polyphenol content.The lavender wastes (SD-L and CO2-L) showed strong antioxidant capacity with potential beneficial effect on addition in foodstuffs. For the first time lavender residues from CO2-extraction was investigated for its antioxidant activity, polyphenol composition and aroma metabolites, and comparison with SD-L was performed. In general, the results suggested that the lavender waste were promising source of antioxidants.

ECDYSTEROIDS AND FLAVONOIDS OF SILENE GRAEFFERI

2021 ◽  
pp. 175-182
Author(s):  
Elena Sergeyevna Filonenko ◽  
Larisa Nikolayevna Zibareva
Keyword(s):  
Aerial Part ◽  
Western Siberia ◽  
Botanical Garden ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
General Tendency ◽  
Vegetative Development ◽  
Promising Source ◽  
First Time ◽  
Active Substances

In this paper Silene graefferi Guss. is recommended for the first time as a promising source of flavonoids and is a well-known producer of ecdysteroids. This perennial species is adapted to the conditions of Western Siberia and has been successfully cultivated in the Siberian Botanical garden of TSU since 2015. It was interesting to study the composition and features of accumulation of biologically active substances during the growth and development of S. graefferi. It was shown that 20-hydroxyecdysone and polypodine B are present in the aerial and underground parts of introduced in culture S. graefferi plants during the entire vegetative development. An unidentified ecdysteroid was detected in the aerial part at the beginning of the vegetation and in the roots during the flowering phase. During vegetative development, common flavonoids and characteristic ones at different periods of plant development were found. The phase of maximum accumulation of ecdysteroids and flavonoids of S. graefferi is the beginning of vegetation, and the minimum is flowering. In the age dynamics the highest levels of biologically active substances in plants were noted at 2 and 3 years of life, then there is a general tendency to decrease with the age of the plant. From the aerial part of S. graefferi, 20-hydroxyecdysone, polypodine B and vitexin were isolated and identified by HPLC.

RESEARCH OF MICROBIOLOGICAL SYNTHESIS OF FATS IN BEET MOLASSES SOLUTIONS

2020 ◽  
Author(s):  
С.О. СЕМЕНИХИН ◽  
О.В. ФЕДОСЕЕВА ◽  
М.В. БАБАКИНА ◽  
Н.М. ДАИШЕВА
Keyword(s):  
Ph Value ◽  
Matter Content ◽  
Biologically Active ◽  
Dry Matter Content ◽  
Microbiological Synthesis ◽  
Vital Activity ◽  
Beet Molasses ◽  
Initial Ph ◽  
First Time ◽  
Active Substances

Проведены исследования обработки растворов свекловичной мелассы 4 штаммами микроорганизмов с целью обогащения растворов жирами. Выявлено влияние начального значения рН, а также оптимального содержания сухих веществ в растворах мелассы, обеспечивающие эффективную жизнедеятельность микроорганизмов с синтезом биологически активных веществ. Установлено, что штаммы R. glutinis Y-332, C. curvatus Y-2236 и U. isabellina F-526 в растворах мелассы с начальным значением рН 8,5 синтезировали жиры в количестве 0,015 0,017 и 0,007 г/г сахаров соответственно штамм R. toruloides Y-334 в растворе мелассы с начальным значением рН 7,0 синтезировал жиры в количестве 0,004 г/г сахаров. Впервые получены экспериментальные данные, позволившие оценить эффективность микробиологического синтеза жиров в растворах мелассы без дополнительного внесения биогенных веществ, а также без поддержания оптимальной рН среды 4 видов микроорганизмов. Обосновано, что штаммы R. glutinis Y-332 и C. curvatus Y-2236 являются наиболее перспективными для обогащения растворов свекловичной мелассы жирами. Research aimed at treatment of beet molasses solutions with 4 strains of microorganisms in order to enrich the solutions with fats has beed established. The influence of the initial pH value, as well as the optimal dry matter content in molasses solutions, which ensure the effective vital activity of microorganisms with the synthesis of biologically active substances, is revealed. It was established that the strains of R. glutinis Y-332, C. curvatus Y-2236 and U. isabellina F-526 in molasses solutions with an initial pH of 8,5 synthesize fats in an amount of 0,015 0,017 and 0,007 g/g of sugars, respectively and the strain of R. toruloides Y-334 in molasses solution with an initial pH value of 7,0 synthesizes fats in an amount of 0,004 g/g of sugars. For the first time, it was obtained the experimental data that made possible to evaluate effectiveness of microbiological synthesis of fats in molasses solutions without nutrient addition, as well as without maintaining the optimal pH of the environment for 4 types of microorganisms. It is proved that R. glutinis strain Y-332 and C. curvatus strain Y-2236 are the most promising strains for enriching beet molasses solutions with fats.

scholarly journals Chemical Composition of Medicinal Plants Growing Under Conditions of Anthropogenic Load (On the Example of the Kursk Region)

2020 ◽  
Vol 6 (4) ◽  
pp. 89-97
Author(s):  
S.A. Kurbatov ◽  
◽  
V.M. Zubkova ◽  
◽  
Keyword(s):  
Heavy Metals ◽  
Betula Pendula ◽  
Raw Materials ◽  
Biologically Active ◽  
Tilia Cordata ◽  
Plant Raw Materials ◽  
High Level ◽  
First Time ◽  
Kursk Region ◽  
Active Substances

in the conditions of the Kursk region, the analysis of soil samples and plant samples for the content of heavy metals was carried out. It is established that the soils of the studied areas are classified as having a high level of pollution in terms of their content. The priority pollutants of the soil are Pb, Zn, Cd, Cr, Ni, and Cu, the supply of which is mainly associated with the enterprises operating in this territory. The content of heavy metals in medicinal plant raw materials is estimated. For the first time, depending on the biological characteristics of Tilia cordata, Betula pendula, Plantago major, Urtica dioica, Achillea millefollium, data on the content of biologically active substances in conditions of technogenic pollution are presented, and the antioxidant activity of plants in areas characterized by various anthropogenic loads is studied.

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