scholarly journals New natural antioxidants

2020 ◽  
Vol 11 (3) ◽  
pp. 967
Author(s):  
Florian Ion Tiberiu Petrescu ◽  
Relly Victoria Virgil Petrescu ◽  
Eleni Mimi Buzea
Keyword(s):  
Antioxidant Enzymes ◽  
Free Radicals ◽  
Significant Role ◽  
Human Body ◽  
Antioxidant Properties ◽  
Natural Antioxidants ◽  
The Body ◽  
Natural Sources ◽  
Optimal Health

Antioxidants are, no doubt, an essential part of an optimal health and even traditional doctors support the importance of an appropriate contribution of antioxidants taken through food. Antioxidants are a category of molecules able to inhibit the oxidation of other molecules. The body distributes various nutrients in the body due to their antioxidant properties and also factory antioxidant enzymes to keep under control the reaction in the chain of free radicals. Some antioxidants are produced by the body, but others don't. In addition, the body's natural ability to produce antioxidants decreases with age. Antioxidants play a significant role for health as it may influence the aging by fighting free radicals. There are antioxidants which can’t be produced in the human body, and to be taken through antioxidant-rich foods, or supplements powerful antioxidant. The paper aims to present some natural sources of oxidants that can be obtained through diet.

scholarly journals Battle between plants as antioxidants with free radicals in human body

2020 ◽  
Vol 9 (3) ◽  
pp. 191-199 ◽  
Author(s):  
Fatemeh Jamshidi-kia ◽  
Joko Priyanto Wibowo ◽  
Mostafa Elachouri ◽  
Rohollah Masumi ◽  
Alizamen Salehifard-Jouneghani ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Free Radicals ◽  
Human Body ◽  
Defense Mechanisms ◽  
Natural Antioxidants ◽  
Redox Status ◽  
The Body ◽  
Antioxidant Agents ◽  
Endogenous Antioxidants

Free radicals are constructed by natural physiological activities in the human cells as well as in the environment. They may be produced as a result of diet, smoking, exercise, inflammation, exposure to sunlight, air pollutants, stress, alcohol and drugs. Imbalanced redox status may lead to cellular oxidative stress, which can damage the cells of the body, resulting in an incidence of various diseases. If the endogenous antioxidants do not stop the production of reactive metabolites, they will be needed to bring about a balance in redox status. Natural antioxidants, for example plants, play an important part in this context. This paper seeks to report the available evidence about oxidative stress and the application of plants as antioxidant agents to fight free radicals in the human body. For this purpose, to better understand oxidative stress, the principles of free radical production, the role of free radicals in diseases, antioxidant defense mechanisms, and the role of herbs and diet in oxidative stress are discussed.

scholarly journals The role of selenium in cardiology

Kardiologiia ◽  
2021 ◽  
Vol 61 (3) ◽  
pp. 96-104
Author(s):  
T. A. Kuropatkina ◽  
N. A. Medvedeva ◽  
O. S. Medvedev
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Enzymes ◽  
Free Radicals ◽  
Cardiovascular Diseases ◽  
Vascular Injury ◽  
Human Body ◽  
Cell Injury ◽  
The Body ◽  
Selenium Status

Selenium is an important micronutrient that is essential for the functioning of the human body. Being a component of the active center of several antioxidant enzymes selenium prevents cell injury by free radicals. Decline in selenium-containing enzymes results in progression of oxidative stress and chronic inflammation, which are considered as possible causes for the development of many cardiovascular diseases. This review focuses on mechanisms for prevention of myocardial and vascular injury through the adequate selenium supply to the body. The importance of monitoring and correction of the selenium status in appropriate patients is underlined.

scholarly journals Beneficial Role of Carica papaya Extracts and Phytochemicals on Oxidative Stress and Related Diseases: A Mini Review

Biology ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 287
Author(s):  
Yew Rong Kong ◽  
Yong Xin Jong ◽  
Manisha Balakrishnan ◽  
Zhui Ken Bok ◽  
Janice Kwan Kah Weng ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Signaling Pathways ◽  
Chronic Diseases ◽  
Carica Papaya ◽  
Antioxidant Properties ◽  
Natural Antioxidants ◽  
The Body ◽  
Health Conditions ◽  
Chemical Components ◽  
Impaired Wound Healing

Oxidative stress is a result of disruption in the balance between antioxidants and pro-oxidants in which subsequently impacting on redox signaling, causing cell and tissue damages. It leads to a range of medical conditions including inflammation, skin aging, impaired wound healing, chronic diseases and cancers but these conditions can be managed properly with the aid of antioxidants. This review features various studies to provide an overview on how Carica papaya help counteract oxidative stress via various mechanisms of action closely related to its antioxidant properties and eventually improving the management of various oxidative stress-related health conditions. Carica papaya is a topical plant species discovered to contain high amounts of natural antioxidants that can usually be found in their leaves, fruits and seeds. It contains various chemical compounds demonstrate significant antioxidant properties including caffeic acid, myricetin, rutin, quercetin, α-tocopherol, papain, benzyl isothiocyanate (BiTC), and kaempferol. Therefore, it can counteract pro-oxidants via a number of signaling pathways that either promote the expression of antioxidant enzymes or reduce ROS production. These signaling pathways activate the antioxidant defense mechanisms that protect the body against both intrinsic and extrinsic oxidative stress. To conclude, Carica papaya can be incorporated into medications or supplements to help manage the health conditions driven by oxidative stress and further studies are needed to investigate the potential of its chemical components to manage various chronic diseases.

PROSPECTS FOR USING ASTRAGALUS ONOBRYCHIS AS A SOURCE OF NATURAL ANTIOXIDANTS

2021 ◽  
pp. 47-53
Author(s):  
Pozdnyakovа Т.А. ◽  
Kuleshovа Е.S. ◽  
Bubenchikov R.A.
Keyword(s):  
Antioxidant Activity ◽  
Free Radicals ◽  
Chemical Interaction ◽  
Raw Materials ◽  
Natural Antioxidants ◽  
The Body ◽  
Plant Raw Materials ◽  
Total Antioxidant ◽  
Promising Source ◽  
The Relationship

The predominance of synthetic and genetically modified foods in the diet of a modern person often leads to disruption of natural metabolic processes and the accumulation of toxic free radicals in the body, which provokes the development of various diseases. Natural antioxidants from medicinal plants can help maintain health and stop the processes of peroxidation. In our opinion, Аstragalus onobrychis can become a promising source of natural antioxidants. The aim of this study was to establish the antioxidant activity in extracts from the herb Astragalus onobrychis. In order to obtain objective and reliable results during our research, we used two methods: the method of titrimetry and spectrophotometry of free radicals. The titrimetric method is based on the chemical interaction between an oxidizing agent (potassium permanganate) and natural antioxidants present in extracts from plant raw materials, since they exhibit the properties of reducing agents. The spectrophotometric method makes it possible to assess the value of antioxidant activity and the duration of the reaction by assessing the interaction of 2,2-diphenyl-1-picrylhydrazil with plant antioxidants. To establish the relationship between the antioxidant activity and the presence of phenolic compounds in the plant, the content of flavonoids and hydroxycinnamic acids in the herb Astragalus onobrychis was determined. As a result of the studies, the total antioxidant activity of extracts from the herb Astragalus onobrychis was established and it was revealed that its value depends on the type of extractant used, since this factor is associated with the content of various groups of natural antioxidants in the extraction. The data obtained indicate the prospects of using the herb Astragalus onobrychis as a source of natural antioxidants.

scholarly journals A Preliminary Up-To-Date Review on Pakistani Medicinal Plants with Potential Antioxidant Activity

2020 ◽  
Vol 11 (1) ◽  
pp. 1-27
Author(s):  
Adil Hussain
Keyword(s):  
Antioxidant Activity ◽  
Free Radicals ◽  
Medicinal Plants ◽  
Natural Antioxidants ◽  
The Body ◽  
New Drugs ◽  
Lung Damage ◽  
Present Review ◽  
Experimental Investigations ◽  
Health Related

Background: There exist natural antioxidants in plants that scavenge harmful free radicals from the body. Free radicals are species of chemical origin with an unpaired electron and play a pivotal role in combating against health-related problems like lung damage, inflammation, and cardiovascular ailments etc. Antioxidants halt the development of these free radicals called the reactive oxygen species either by chelating the trace elements or by enzymes inhibition. Objectives: The aim of present review was to collect information about Pakistani medicinally important plants with the exploration of their antioxidant potential. Methodology: Total 206 papers were looked over, which were obtained from numerous sources like; Google Scholar, Medline, PubMed, Research Gate, Science Direct, Scopus and Web of Science. Results: Overall, 93 plants representing 44 families with potential antioxidant activity reported from Pakistan have been presented in this review. Maximum number of species from Asteracea, Poaceae and Rutaceae familes were scrutinized for their potential antioxidant activity from Pakistan. Conclusion: The present review clearly designates that the presence of phytochemicals and antioxidant activity of medicinal plants from Pakistan vary with the species of the plants and material/extracts used. From this review, it is recommended to perform comprehensive experimental investigations based on toxicology and ethnopharmacology on these precious plants from Pakistan. It will be advantageous in the provision of trustworthy information to patients and determine further innovative compounds for safer and new drugs development with fewer side effects.

scholarly journals Phenols and Melanoidins as Natural Antioxidants in Beer. Structure, Reactivity and Antioxidant Activity

Biomolecules ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 400 ◽  
Author(s):  
Alvaro Martinez-Gomez ◽  
Isabel Caballero ◽  
Carlos A. Blanco
Keyword(s):  
Antioxidant Activity ◽  
Free Radicals ◽  
Antioxidant Properties ◽  
Natural Antioxidants ◽  
Antioxidant Compounds ◽  
Appreciable Effect ◽  
Human Metabolism ◽  
The World ◽  
Maillard Products ◽  
By Products

Beer is one of the most consumed drinks around the world, containing a variety of compounds that offer both appreciated sensorial characteristics and health advantages. Important healthy compounds in beer are those with antioxidant properties that attenuate the content of free radicals produced as by-products in the human metabolism, exerting an appreciable effect against cancers or cardiovascular diseases. This work details a study of antioxidant compounds present in beer, focusing on the two main groups: phenols (including polyphenolic forms) and melanoidins, formed specifically during brewing as Maillard products. The fundaments of the most important methods to evaluate beer antioxidant activity, the main antioxidant compounds present in beer—especially those with healthy properties—and the new trends to increase beer antioxidant activity are also discussed.

scholarly journals Advances on antioxidants in research and applications

2019 ◽  
Vol 131 ◽  
pp. 01009
Author(s):  
Ruirui Song ◽  
Qi Wu ◽  
Lin Zhao ◽  
Zhenyu Yun
Keyword(s):  
Oxidative Stress ◽  
Free Radicals ◽  
Chronic Diseases ◽  
Significant Role ◽  
Human Body ◽  
Relevant Research ◽  
Redox Equilibrium ◽  
Practical Applications ◽  
Existing Problems ◽  
Prevention And Treatment

Antioxidants play a significant role in the prevention and treatment of numerous chronic diseases as they prevent oxidative stress and maintain reduction-oxidation (redox) equilibrium in the human body by eliminating reactive free radicals effectively. This study focused on the types and applications of antioxidants and discussed the existing problems with regard to the practical applications of antioxidants. Also, it presented a review of the latest research on antioxidants in China and abroad and performed a comprehensive, objective analysis of relevant research on antioxidants.

scholarly journals Activities of Some Antioxidant Enzymes in Some Tissues of Acetaminophen-Induced Hepatotoxic Albino Rats Treated with Anacardium Occidentale Stem Bark Aqueous Extract

2020 ◽  
Vol 1 (4) ◽  
Author(s):  
Philip O. Amira ◽  
Adebayo S. Daramola ◽  
Mike O. Sanni
Keyword(s):  
Superoxide Dismutase ◽  
Antioxidant Enzymes ◽  
Free Radicals ◽  
Aqueous Extract ◽  
Antioxidant System ◽  
Stem Bark ◽  
The Body ◽  
Anacardium Occidentale ◽  
Albino Rats ◽  
Wide Range

Liver is a vital organ present in vertebrates, which has a wide range of functions including aiding of digestion, detoxification and protein biosynthesis. But the ability of the liver to perform these functions can be compromised by numerous substances it is daily exposed to, including certain medicinal agents which when taken in over doses. Liver damage, just like many other diseased conditions can lead to oxidative stress, especially when the body’s antioxidant system is overwhelmed by the free radicals thus generated. A major component of this antioxidant system are the natural antioxidant enzymes superoxide dismutase and catalase manufactured in the body, which provide an important defense against free radicals usually generated in diseased conditions. Most synthetic anti-hepatotoxicity drugs available present serious side effects and are generally out of reach of the common man. Consequently, the effect of administration of aqueous extract of Anacardium occidentale stem bark on the activities of superoxide dismutase and catalase in some tissues of acetaminophen-induced hepatotoxic rats was investigated. There was a significant (p < 0.05) reduction in the activities of superoxide dismutase and catalase in the serum, liver, kidney and heart of the hepatotoxic rats. However, treatment of hepatotoxic rats with aqueous extract of Anacardium occidentale stem bark led to a significant (p < 0.05) increase in the activities of superoxide dismutase and catalase in the serum, liver, kidney and heart of acetaminophen-induced hepatotoxic rats.

scholarly journals Inter-relationship between Annavaha Srotas and Agni W.S.R. Shodhana Therapy

2020 ◽  
Vol 1 (1) ◽  
pp. 54-60
Author(s):  
Mahesh Prasad Sah ◽  
Bijendra Shah ◽  
Gouri Chauhan ◽  
OP Singh
Keyword(s):  
Gastrointestinal Tract ◽  
Significant Role ◽  
Human Body ◽  
Digestive System ◽  
The Body ◽  
Disease Elimination

Ayurveda defines human body is made of different gross and subtle channels called srotas. Srotas are the channels through which different elements undergo transformation, transmutation, circulation and transportation. The srotas is an integral part of the body, serving as a route to conduct or convey a substance from one place to other. There are 13 major srotas mentioned. The Srotas or channels which carry Anna or Food is called Annavaha Srotas. Some authorities equate the Annavaha Srotas with the some parts of digestive system or the gastrointestinal tract. Agni, the transformative energy, in the Annavaha srotas digest and transforms the food into components suitable for the body. Impairment of function of agni is root the cause of the disease, which manifest either in Annavaha srotas or other srotas in the body. Thus, correction of agni is the prime in treatment of any disease. Elimination of vitiated doshas by Pancakarma procedure viz Vaman and Virechana has shown to have impact on agni through various guna in the drugs used in these therapy. Sodhana procedures has a significant role in improving the function of agni and restoring the health.

PERBEDAAN UJI AKTIVITAS ANTIOKSIDAN ANTARA EKSTRAK BUAH KIWI DAN APEL SECARA IN VITRO

2020 ◽  
Vol 10 (1) ◽  
pp. 90
Author(s):  
Nur Ariska Nugrahani
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Free Radicals ◽  
Natural Antioxidants ◽  
Apple Fruit ◽  
The Body ◽  
Fruit Extract ◽  
Kiwi Fruit ◽  
Dpph Method

Radikal bebas yang berbahaya jika konsentrasi ROS akan meningkat sehingga akan mengakibatkan stress oksidatif. Stress oksidatif biasanya disebabkan oleh konsentrasi tinggi dari radikal bebas dalam sel dan jaringan yang dapat diinduksi oleh beberapa faktor negatif seperti gamma, UV, radiasi sinar-X, tekanan psiko-emosional dan makanan yang tercemar.Untuk meminimalisir radikal bebas dalam tubuh diperlukan antioksidan alami seperti ekstrak buah kiwi dan ekstrak buah apel. Uji aktivitas antioksidan pada masing- masing ekstrak dilakukan dengan metode DPPH (1,1- difenil-2-pikrihidazil). Hasil menunjukkan bahwa nilai IC50 dari ekstrak buah kiwi lebih rendah daripada IC50 ekstrak buah apel. Hal ini menunjukkan bahwa ekstrak buah kiwi mempunyai aktivitas antioksidan lebih kuat dari ekstrak buah apel. Keyword : Radikal bebas, DPPH, Ekstrak buah kiwi, Ekstrak buah apel Free radicals will be dangerous if the ROS concentration will increase and causes oxidative stress. Oxidative stress is usually caused by high concentrations of free radicals in cells and tissues which can be induced by several negative factors such as gamma, UV, X-ray radiation, psycho-emotional pressure and contaminated food. To minimize free radicals in the body natural antioxidants such as kiwi fruit extract and apple extract. The antioxidant activity test on each extract was carried out by the DPPH method (1,1-diphenyl-2-picrihydazyl). The results showed that IC50 value of kiwi fruit extract was lower than IC50 of apple fruit extract. This shows that kiwi fruit extract has stronger antioxidant activity than apple extract. Keyword : free radicals, DPPH, kiwi fruit extract, apple fruit extract

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