scholarly journals Functioning of Patients with Myasthenia Gravis after Plasmapheresis

2019 ◽  
Vol 8 (4) ◽  
pp. 143-147
Author(s):  
Monika Biercewicz ◽  

Introduction. Myasthenia gravis is an autoimmune disease of the postsynaptic part of the neuromuscular junction. A characteristic symptom of myasthenia gravis is the so-called fatigability or muscle fatigue, which also affects the respiratory muscles. Plasmapheresis is one of the treatments that improve breathing and reduce the symptoms that cause muscle weakness. Aim. The aim of the study was to assess the functioning of patients with myasthenia gravis before and after plasmapheresis. Material and Methods. The research was conducted in 2019 in the Anaesthesiology and Intensive Care department on a group of 30 patients with clinically confirmed myasthenia gravis. The author’s questionnaire was used to assess the functioning of patients. The research was approved by the Bioethics Committee. Results. The patient’s condition improved after the procedure in each of the analysed areas of functioning (physical activity, movement, breathing, swallowing, mood, social functioning). The plasmapheresis most preferably affected the area of physical activity of the subjects. The conducted statistical analysis proved a significant difference (p = 0.000) for all results, in every aspect (before and after the procedure). At the same time, the highest average increase was observed in relation to physical activity — an increase of 3.17 points. Conclusions. Plasmapheresis had a positive effect on patients’ health in both physical and mental aspects. (JNNN 2019;8(4):143–147) Key Words: myasthenia gravis, plasmapheresis, functional assessment

2018 ◽  
Vol 25 (3) ◽  
pp. 796-815 ◽  
Author(s):  
Juha Kokkonen ◽  
Sami Yli-Piipari ◽  
Marja Kokkonen ◽  
John Quay

This study investigated the effectiveness of a creative physical education (CPE) intervention on students’ perceptions of motivational climate in physical education (PE), leisure-time physical activity (PA) motivation, and overall PA. A sample of 382 fourth to sixth grade students ( Mage= 10.87[.93]) from two elementary schools were assigned to the CPE intervention ( n = 196; Mage= 10.84[.95]) and control ‘PE-as-usual’ ( n = 186; Mage= 10.90[.90]) groups. Students’ perceived task- and ego-supportive climate in PE, leisure-time PA motivation, and overall PA were measured before and after the one-year intervention. Analyses of covariance and path analyses were implemented to test the effectiveness of the intervention. The intervention had a positive effect on students’ perceptions of task-supportive climate in PE ( p < .001) and a negative effect on ego-supportive climate ( p < .001). Students’ perceptions of task-supportive climate had a positive effect on their leisure-time PA motivation ( p < .001), which, in turn, had a positive effect on their overall PA ( p < .001). The results suggest that CPE-based PE may increase students’ perceptions of task-supportive climate in PE, which predicts their later leisure-time PA motivation outside the school context and overall PA.


2017 ◽  
Vol 36 (03) ◽  
Author(s):  
Kirti . ◽  
B. Jirli ◽  
Pankaj Kumar Mandal

Bihar is one of the poorest and most populous states in India. The share of employment in agriculture and allied activities is 68.9 percent in Bihar. This study is attempting to undertake a micro level analysis of collected data to assess the investment as well as return in Dairy activity carried out by Jeevika project in Muraul Block of Muzaffarpur District. Study revealed that calculated ‘t’ value of investment (12.533) and return (19.589) was more than table‘t’ value (1.977) of investment and return respectively. Comparison among investment as well as return in Dairy activity practiced by the respondents, before and after joining the project through paired t-test, showed a significant difference hence providing positive effect on the life of project beneficiaries.


2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 190-190
Author(s):  
Seok Shin Tan

Abstract Objectives This study aimed to investigate the association between dietary antioxidant intake and blood lactate level among 20–55 years old Malaysian adults. Methods Subjects (N = 80) of this cross-sectional study were recruited through convenience sampling. Sole Fitness LCB Upright Bike was used to conduct the modified Wingate Anaerobic Test. Dietary antioxidant level was assessed by using Malaysian Adult Nutrition Survey (MANS) 2014 food frequency questionnaire. Short Form International Physical Activity Questionnaire (IPAQ) was used to assess the physical activity level of the subjects. Blood lactate concentration was assessed by The Edge TM blood lactate analyzer, before and after exercise. Saliva samples were collected from subjects for total antioxidant capacity determination using the 2,2-diphenyl-1- picryl-hydrazyl test of saliva (DPPHS) assay. Data was analyzed using SPSS version 25.0. Results The median of total antioxidant intake among Malaysian male and female adults were 1030.64 (734.74) and 9392.90 (10360.44) mg/day, respectively. A significant difference between the means blood lactate level before and after exercise was observed, however, no significant difference in the mean salivary total antioxidant capacity (TAC) before and after exercise. No significant association observed between the total antioxidant intake and salivary TAC before exercise for both males and females, whereas a significant positive moderate association was observed after exercise for females. A significant inverse moderate association between blood lactate level and salivary TAC before exercise was observed among the males in the present study but no association found after exercise for both males and females. Conclusions Present study indicated no significant association between the total dietary antioxidant intake and blood lactate level among Malaysian adults aged 20–55 years old. Future research with larger sample size should develop strategically to confirm these initial findings. Funding Sources International Medical University, Malaysia


2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Ronald Sondakh ◽  
Damajanty Pangemanan ◽  
Sylvia Marunduh

Abstract : Triglycerides are one of fat body. Elevated levels of triglycerides occur because of obesity, alcohol consumption, sugar, and lack of activity, induced accumulation of triglycerides in the blood. Elderly is individuals with a restriction of physical activity due to physical conditions or disallowance of the family. This restriction leads to reduced physical activity that very useful for lowering triglycerides level. This causes an increase triglyceride levels. This study aims to look at the influence of elderly aerobics exercise on triglyceride levels. This research was an experimental design of the field with pre-post one group test. Samples were 30 elderly that lived in BPLU Senja Cerah, Paniki Bawah. Samples fasting for 8 hours to blood sampling. Tests performed are elderly aerobics exercise performed for 30 minutes in a 3x a week for 3 weeks. The results analyze with paired sample t-test to determine  the differenc e in the results  triglyceride levels before and after exercise. The  obtained  results  showed  a highly significant difference between  triglycerides levels before and after exercise with α = 0,004 (<0,05) as shown by thitung (3.153) > Ttabel (2.045) Elderly aerobics exercise showed a significant effect in reducing trigiyceride levels in the blood. Keyword: elderly aerobics exercise, triglycerides, elderly.   Abstrak: Trigliserida merupakan salah satu lemak didalam tubuh. Peningkatan kadar trigliserida terjadi karena kegemukan, konsumsi alkohol, gula, serta kurangnya aktivitas sehingga menyebabkan penumpukan trigliserida dalam darah. Lansia merupakan individu yang mengalami pembatasan aktivitas fisik dikarenakan kondisi fisik atau larangan dari keluarga. Pembatasan ini menyebabkan berkurangnya aktivitas fisik yang berguna untuk menurunkan kadar trigliserida dalam darah. Hal ini menyebabkan peningkatan kadar trigliserida dalam darah. Penelitian ini bertujuan untuk melihat pengaruh senam bugar lansia terhadap kadar trigliserida. Penelitian ini bersifat ekperimental lapangan dengan rancangan pre-post one group test. Sampel berjumlah 30 orang yang merupakan Lansia yang berada di BPLU Senja Cerah, Paniki Bawah. Sampel berpuasa selama 10 jam sebelum dilakukan pengambilan darah. Tes yang dilakukan adalah senam bugar lansia yang dilakukan selama 30 menit dalam 3x seminggu selama 3 minggu. Hasil yang didapatkan diolah dengan uji t berpasangan untuk melihat perbedaan hasil kadar trigliserida sebelum melakukan senam dan setelah melakukan senam.  Hasil yang didapatkan menunjukkan perbedaan yang sangat signifikan antara  kadar trigliserida lansia sebelum senam dan sesudah senam dengan α = 0,004 (<0,05%) hal ini ditunjukkan dengan thitung (3,153) > ttabel (2,045). Senam bugar lansia memberikan pengaruh yang sangat signifikan dalam menurunkan kadar trigliserida dalam darah. Kata Kunci: aktivitas fisik, senam bugar, trigliserida, lansia.


2010 ◽  
Vol 9 (1) ◽  
pp. 59-62
Author(s):  
Diego Luis Ballio Santana ◽  
Rodrigo Cruz Pinto ◽  
Alessandro Finkelsztejn ◽  
Yara Dadalti Fragoso

OBJECTIVES: The purpose of the present study was to assess the influence of a tailored physical activity program on specific parameters in Parkinson Disease (PD) patients. METHOD: PD patients were assessed before and after six months of a tailored physical activity program. Twenty PD patients (13 M, 7 F), mean age 55 years. Aerobic, resistance and stretching exercises. No special apparatus or machine was used at any stage of the program. There was no interference with the pharmacologic treatment, which remained at the discretion of the physician in charge. Fatigue, disability, joint amplitude, cardiorespiratory parameters and body fat composition were assessed. Comparisons were performed using the Student’s t-test at baseline and after six months. RESULTS: There was a significant (p0.001) and positive effect of this physical activity program in all assessed parameters. CONCLUSIONS: Despite this chronic, disabling and progressive neurological disease, PD patients showed significant improvement in all assessed parameters after participating in a specific and tailored physical activity program.


2020 ◽  
Vol 17 (3) ◽  
Author(s):  
Kok J.L ◽  
Asma’, A. ◽  
Khairil-Shazmin K ◽  
Hayati M.Y

Introduction: The aim of this study was to determine the effects of pedometer-based intervention and the relationship between daily walking steps and nutritional status among overweight/obese university students in Kuala Terengganu. Materials and methods: The study was an 8-week intervention study that included 23 overweight/obese university students. After 7 days of baseline activity, anthropometric data such as weight, height and waist circumference and a one-day dietary record were taken. The participants were divided into a control and case group. The control group (n=15) was instructed to continue with their normal activities and habits throughout the 8 weeks. The case group (n=8) was instructed to walk based on the targeted number of steps. Data such as body weight, waist circumference and a one-day dietary record were taken after the intervention. Results: Both case and control group show significant differences in body mass index (BMI) with p=0.017 and p=0.047 respectively. However, there is a large and significant difference between walking steps and BMI before and after intervention for the case group. There were no differences in any other study parameters during the 8-week study. Conclusion: In conclusion, short-term intervention with a pedometer increased physical activity and positively affected the BMI of overweight/obese participants. The use of a pedometer was efficient in measuring daily physical activity (r= 0.756, p< 0.05).


2020 ◽  
Author(s):  
Arwa Alumran

BACKGROUND Regular physical activity has a direct association with an improvement in perceived health-related quality of life (HRQL). Because many Saudis are reportedly inactive, Imam Abdulrahman bin Faisal University established a walking challenge for all university employees to encourage a better lifestyle and to promote health awareness. OBJECTIVE This study aims to measure the differences in the participants’ HRQL scores before and after the challenge. METHODS a HRQL survey is sent to all university employees before the implementation of a pedometer-based walking challenge at the study setting. The questionnaire is re-sent after the challenge ended and differences in the overall HRQL were calculated. A RAND SF20-items scale was used to measure the participants’ HRQL scores, along with other information such as academic qualifications. RESULTS Most of the participants were between 31 and 50 years old, and 40% were males. There was a statistically significant difference in the overall HRQL scores before and after the walking challenge intervention. The HRQL score increased from 50.77 before the challenge to 55.53 after the challenge (paired t-test = -4.322, P < .0001). An odds ratio (OR) showed that the odds of having higher HRQL scores increased by 88% after the walking challenge, compared to before the walking challenge (OR = 1.88; 95% CI= 1.269-2.809; P = .002). CONCLUSIONS Physical activity by itself can improve a community’s overall health and quality of life. Similar interventions are encouraged in all public and private sectors in the country. CLINICALTRIAL NA


Author(s):  
Somaye Pouy ◽  
Abolfazl Etebarian Khorasgani ◽  
Ali Azizi-Qadikolaee ◽  
Yasaman Yaghobi

Abstract Introduction Tonsillectomy is one of the most common pediatric surgeries in the world and pain control following tonsillectomy is very important. Objective The aim of this study is to investigate the effect of acupressure on the amount of pain following tonsillectomy in children. Method One hundred and forty-four children aged 5–12 years old were assigned into one of three groups: interventions, control and placebo. In the intervention group, acupressure was applied at three acupoints and in the placebo group, sham acupressure was applied. In the control group routine care only was applied. Results There was a significant difference between an average of changes in pain score before and after the intervention during the 3 time periods after the tonsillectomy operation in the acupressure group (p = 0.002). Conclusion The results showed that acupressure had a positive effect on pain reduction after tonsillectomy in children in the intervention group.


Animals ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 51 ◽  
Author(s):  
Lauren Powell ◽  
Kate M. Edwards ◽  
Adrian Bauman ◽  
Adam J. Guastella ◽  
Bradley Drayton ◽  
...  

Several studies suggest human–dog interactions elicit a positive effect on canine oxytocin concentrations. However, empirical investigations are scant and the joint influence of human–dog interaction and physical activity remains unexplored. The aims of the current study were to (a) examine the canine endogenous oxytocin response to owner-led dog-walking and affiliative human–dog interactions and (b) investigate the moderating effect of the owner-reported strength of the human–dog bond on such responses. Twenty-six dogs took part in a random order cross-over trial, involving dog-walking and human–dog interactions. Urinary samples were collected before and after each condition. The data were analyzed using linear mixed models with condition, order of conditions, condition duration, and latency from initiation of condition to urine sample collection considered as fixed effects, and the participant was considered a random effect. Canine urinary oxytocin concentrations did not differ significantly following dog-walking (mean change: −14.66 pg/mg Cr; 95% CI: −47.22, 17.90) or affiliative human–dog interactions (mean change: 6.94 pg/mg Cr; 95% CI: −26.99, 40.87). The reported strength of the human–dog bond did not significantly moderate the canine oxytocin response to either experimental condition. Contrary to our hypothesis, we did not observe evidence for a positive oxytocin response to dog-walking or human–dog interactions.


2019 ◽  
Vol 8 (2) ◽  
pp. 68-72
Author(s):  
Said Junaidi ◽  
Dian Listiarini

 ABSTRAK Tujuan penelitian ini untuk mengetahui pengaruh kombinasi latiahan aerobic dan asupan kafein untuk menurunkkan Body Mass Index dan Percent Body Fat Pada Wanita Overweight. Penelitian eksperimental ini dilakukan pada 12 wanita usia 19-22  tahun. Desain penelitian Treatment by subject, perlakuan 1  Latihan Aerobik 14 kali sesi dan perlakuan 2 pemberian Kafein dan Latihan Aerobik 14 kali sesi. Subyek diukur BB, TB (BMI), PBF (skinfold callifer) sebelum dan sesudah perlakuan. Hasil penelitian terjadi penurunan BMI pada P2 lebih  tinggi daripada P1 (0,75+0,39; 0,44+0,23), hasil uji t-test menunjukan hasil perbedaan yang signifikan 0,041 (p<0,05). Penurunan PBF pada P2 lebih tinggi dibandingkan P1 (0,84±0,23; 0,42±0,30), uji t-test menunjukan hasil perbedaan yang signifikan 0,001 (p<0,05). Simpulan dan saran: efek latihan aerobik dan pemberian kafein dapat menurunkan body mass index dan percent body fat pada wanita overweight usia 19-22 tahun. Kata kunci : BMI; kafein; latihan aerobik; overweight; PBF.  ABSTRACT Controlling body weight can be done with aerobic physical activity. Besides caffeine in the body's metabolism can also reduce body mass and percent fat, if both are combined can provide a more effective influence in reducing Body Mass Index and Percent Body Fat in Overweight of female. This experimental study was conducted on 12 women aged 19-22 years. Research design Treatment by subject, treatment 1; Aerobic exercise 14 sessions and treatment 2 Caffeine and Aerobic Exercise 14 sessions. Subjects measured BB, TB (BMI), PBF (skinfold callifer) before and after treatment. The results of the study showed a decrease in BMI in P2 higher than P1 (0.75 + 0.39; 0.44 + 0.23), the results of the t-test showed a significant difference of 0.041 (p <0.05). The decrease in PBF in P2 was higher than P1 (0.84 ± 0.23; 0.42 ± 0.30), the t-test showed a significant difference of 0.001 (p <0.05). Conclusion: the effect of the combination of aerobic exercise and caffeine intake is more effective in reducing body mass index and percent body fat in overweight of female. Keywords: aerobic exercise; BMI; caffeine; overweight; PBF.


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