scholarly journals Contamination of hen manure with nine antibiotics in poultry farms in Ukraine

2019 ◽  
Vol 10 (4) ◽  
pp. 532-537
Author(s):  
L. V. Shevchenko ◽  
Y. V. Dobrozhan ◽  
V. M. Mykhalska ◽  
T. Y. Osipova ◽  
V. V. Solomon
Keyword(s):  
Infectious Diseases ◽  
Medication Use ◽  
Poultry Manure ◽  
The Body ◽  
Residual Content ◽  
The World ◽  
Poultry Farms ◽  
Antibacterial Medication ◽  
Therapeutic Doses ◽  
Tetracycline Group

The problem of processing, use and utilization of poultry manure contaminated with antibiotics remains unsolved not only Ukraine but around the world, and theatment and prevention of highly contagious infectious diseases among birds requires antibacterial medication use. By liquid chromatography, 293 hen manure samples of 12 Ukrainian industrial flocks of poultry farms were studied. The residual content of 9 antibiotics in the hen manure was found, including 38.2% of tetracycline preparations (doxycycline, oxytetracycline, tetracycline and chlortetracycline), fluoroquinolone (enrofloxacin and norfloxacin) including combinations of incompatible tetracyclines and fluoroquinolones, broad-spectrum penicillins (amoxicillin), fenicols (florfenicol), macrolides (tylosin) and one sulfanilamide preparation (sulfametazine). The most common antibiotics in hen manure of Ukrainian industrial flocks of poultry farms are the antibiotics of the tetracycline group, the main one being doxycycline. A high correlation was determined between the release of doxycycline with eggs and hen manure after the preparation was used perorally in preventive and therapeutic doses. Time of complete excretion of doxycycline from the hen body at the preventive dose (50 mg/L of water for 7 days) was 14 days for manure, 8 days for eggs, following its withdrawal, and at the therapeutic dose (100 mg/L of water for 7 days ) – 20 days for manure, and 9 days for eggs, following its withdrawal. The perspective of using the obtained data about the duration of excretion of doxycycline with hen manure consists in confirmation of the time of the antibiotic’s excretion with manure following its use for preventive or therapeutic purpose, which will help in controlling it as a source of environmental pollution. The time of doxycycline excretion from the body of hens with eggs and manure may be used practically by professionals in veterinary medicine in the case of prescribing or replacing antibiotics for treatment of infectious diseases of poultry to prevent the combination of incompatible preparations in the body and manure. The obtained experimental data may form the basis for the development of national regulations on the processing, usage and utilization of manure of hens under treatment with antibiotics.

scholarly journals ВИВЧЕННЯ ПРОТИВІРУСНОЇ АКТИВНОСТІ ТАБЛЕТОК АЛЬТАБОР

2015 ◽  
Author(s):  
С. Л. Рибалко ◽  
Т. В. Крутських ◽  
А. С. Шаламай
Keyword(s):  
Antiviral Activity ◽  
Infectious Diseases ◽  
Epstein Barr Virus ◽  
Therapeutic Index ◽  
The Body ◽  
Herpes Viruses ◽  
Barr Virus ◽  
The World ◽  
Influenza Activity ◽  
Epstein Barr

<p><strong>STUDY OF ANTIVIRAL ACTIVITY OF TABLETS ALTABOR </strong></p><p><strong>S.L. Rybalko<sup>1</sup>, </strong><strong>Т</strong><strong>.V. </strong><strong>К</strong><strong>rutskikh<sup>2</sup>, </strong><strong>А</strong><strong>.S. Shalamay<sup>3</sup></strong></p><p><sup>1</sup>L.V.Gromashevsky Institute of epidemiology and infectious diseases Academy of Medical Science of Ukraine, Kyiv</p><p><sup>2</sup>National Pharmaceutical University, Kharkiv</p><p><sup>3</sup>JSC SIC "Borshchahivka CPP", Kyiv</p><p><strong>Summary:</strong> studied antiviral activity of tablets Altabor. Determined that the drug has antiviral activity and inhibits the reproduction of Epstein-Barr virus.</p><p><strong>Key words:</strong> altabor, antiviral activity, influenza, Epstein-Barr virus.</p><p><strong>Introduction.</strong> Among all infectious diseases flu and SARS took first place in frequency and the number of cases in the world and account for 95%. According to WHO influenza and flu-like illness in the world is sick 5 - 30 % of the population is 500 million people. For 400 years the world's recorded over 100 epidemics of influenza pandemics and 18, which bring it with them tens of millions of lives. Today, global losses from influenza epidemics is much inferior to the scale of past pandemics due to the possibilities of modern diagnosis of the virus , the availability of antiviral and antibacterial drugs and improving health services. But the problem of treatment of disease really matter remains relevant.</p><p>Against the background of acute viral infections of herpes viruses can be said not, but no less threatening. Herpes was first fixed in a thousand years BC, but the problem that attracts attention, was only in the 20th century after the emergence of HIV. Today open 80 more members of the family of herpes viruses, of which 8 types pathogenic to man. One of the pathogenic types are Epstein-Barr virus, which, according to research antibodies detected in 95% of the population. At this time this virus play an important role in the formation of cancer cells in the body that causes the need for increasing attention from the medical and pharmaceutical community.</p><p>Create antiviral agents is one of the most difficult tasks chemotherapy infections. The reason is that viruses containing RNA and DNA components are obligate intracellular parasites. In the process of viral replication is mainly used machine biosynthesis microorganism cells, modifying its outstanding manner. In this regard, it is very difficult to find selective operating means which would killed viruses without damaging the cells are "master". However, in recent years, certain antiviral drugs that possess outstanding selective action against the infected cells and suppress the virus replicative cycle. One of these drugs is original domestic product - Altabor tablets.</p><p><strong>Methods.</strong> Antiviral activity of Altabor tablets studied in models in vitro. To determine influenza activity using dog kidney cell culture .The influence of tablets Altabor on virus Epstein-Barr conducted in the system Raji cells infected with the said virus.</p><p><strong>Results and discussion</strong>. Altabor tablets influenza activity based on the inhibition of viral neuraminidase, an enzyme responsible for viral virion ability to penetrate the host cell and leave it after reproduction. Analyzing these data, it should be noted that tablets Altabor actively inhibit the reproduction of the influenza virus in doses from 100 mg/ml to 6.75 ug/ml 7.5-3.0 lg ID50, which indicates a strong flu drug activity. As for the study of the effect of tablets on Altabor Epstein-Barr virus, the maximum tolerated concentration was 750 mg/ml. Determined that the minimum active concentration for the drug was 0.1 mg/ml. Based on the value of the minimum and maximum tolerated concentration of active therapeutic index of tablets Altabor established at 5000, indicating a pronounced effects on reproduction of the virus.</p><p><strong>Conclusions.</strong> Result of studies on the antiviral activity of tablets Altabor found that the preparation has flu activity. Also, the drug inhibits the reproduction of Epstein-Barr virus, as evidenced therapeutic index of tablets Altabor set at 5000.</p>

scholarly journals Causative agents of campylo-bacteriosis of birds – etiological factors of toxicoinfections in humans

2021 ◽  
Author(s):  
A.A. Sukhinin ◽  
T.N. Rozhdestvenskaya ◽  
S.V. Pankratov ◽  
L.I. Smirnova ◽  
S.A. Makavchik
Keyword(s):  
Infectious Diseases ◽  
Egg Production ◽  
Raw Materials ◽  
Well Being ◽  
The Body ◽  
Transmission Factor ◽  
Economic Damage ◽  
Poultry Products ◽  
Poultry Farms ◽  
Causative Agents

This article is devoted to the problems of the emergence among the population of acute intestinal infectious diseases of a zoonotic nature caused by campylobacteriosis. According to WHO estimates, for many years the dominant cause in the development of acute intestinal infectious diseases in humans of a zoonotic nature is campylobacteriosis, which has recently surpassed salmonellosis in prevalence. Campylobacteriosis is a zoonotic infectious disease of agricultural, domestic and wild birds, animals and humans, caused by microorganisms of the genus Campylobacter, characterized by varying degrees of severity and polymorphism manifestations. Bacteria of the Campylobacter genus are ubiquitous in nature, they are present in the body of poultry and animals. The main reservoirs of Campylobacter are wild and domestic birds, primarily chickens. The high infection rate of C. jejuni of poultry flocks leads to more frequent detection of these bacteria in various types of poultry products. As a result, raw materials and poultry products are considered the main source of excretion and transmission factor of campylobacteriosis pathogens, posing the greatest risk to human health, since chicken meat and eggs occupy one of the dominant places in the population's diet. A high percentage of C. jejuni bacteria carriers among poultry, in case of violation of veterinary and sanitary measures in the farm and against the background of other latent infections, can cause significant economic damage to poultry farming due to a decrease in egg production, weight, mortality of poultry and an increase in the cost of health measures. Today, the system for controlling the spread of campylobacteriosis in poultry farms and at poultry processing enterprises is based on the use of general veterinary-zoo hygienic and antiepizootic measures, which does not always prevent infection of poultry, poultry products and, accordingly, people. In this regard, the development of a National Program for the Control of Campylobacteriosis in Poultry Farms of the Russian Federation in order to ensure the epidemiological well-being of the population is relevant.

Scanning electron microscopy of freeze-fractured prescapular lymph node of caprine

1984 ◽  
Vol 42 ◽  
pp. 244-245
Author(s):  
O. Faroon ◽  
F. Al-Bagdadi ◽  
T. G. Snider ◽  
C. Titkemeyer
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Lymphatic System ◽  
Three Dimensional ◽  
Meat Products ◽  
The Body ◽  
Morphological Data ◽  
The World ◽  
Cellular Constituent ◽  
Scanning Electron

The lymphatic system is very important in the immunological activities of the body. Clinicians confirm the diagnosis of infectious diseases by palpating the involved cutaneous lymph node for changes in size, heat, and consistency. Clinical pathologists diagnose systemic diseases through biopsies of superficial lymph nodes. In many parts of the world the goat is considered as an important source of milk and meat products.The lymphatic system has been studied extensively. These studies lack precise information on the natural morphology of the lymph nodes and their vascular and cellular constituent. This is due to using improper technique for such studies. A few studies used the SEM, conducted by cutting the lymph node with a blade. The morphological data collected by this method are artificial and do not reflect the normal three dimensional surface of the examined area of the lymph node. SEM has been used to study the lymph vessels and lymph nodes of different animals. No information on the cutaneous lymph nodes of the goat has ever been collected using the scanning electron microscope.

HIPEREMESIS GRAVIDARUM PADA IBU HAMIL DI KLINIK BIDAN SUPRIYATI SRIBIT BERBAH SLEMAN

2019 ◽  
Vol 14 (1) ◽  
pp. 51
Author(s):  
Pramukti Dian Setianingrum ◽  
Farah Irmania Tsani
Keyword(s):  
Blood Pressure ◽  
Pregnant Women ◽  
Hyperemesis Gravidarum ◽  
Unwanted Pregnancy ◽  
The Body ◽  
Nausea And Vomiting ◽  
Daily Activities ◽  
World Health ◽  
The World

Backgroud: The World Health Organization (WHO) explained that the number of Hyperemesis Gravidarum cases reached 12.5% of the total number of pregnancies in the world and the results of the Demographic Survey conducted in 2007, stated that 26% of women with live births experienced complications. The results of the observations conducted at the Midwife Supriyati Clinic found that pregnant women with hyperemesis gravidarum, with a comparison of 10 pregnant women who examined their contents there were about 4 pregnant women who complained of excessive nausea and vomiting. Objective: to determine the hyperemesis Gravidarum of pregnant mother in clinic. Methods: This study used Qualitative research methods by using a case study approach (Case Study.) Result: The description of excessive nausea of vomiting in women with Hipermemsis Gravidarum is continuous nausea and vomiting more than 10 times in one day, no appetite or vomiting when fed, the body feels weak, blood pressure decreases until the body weight decreases and interferes with daily activities days The factors that influence the occurrence of Hyperemesis Gravidarum are Hormonal, Diet, Unwanted Pregnancy, and psychology, primigravida does not affect the occurrence of Hyperemesis Gravidarum. Conclusion: Mothers who experience Hyperemesis Gravidarum feel nausea vomiting continuously more than 10 times in one day, no appetite or vomiting when fed, the body feels weak, blood pressure decreases until the weight decreases and interferes with daily activities, it is because there are several factors, namely, hormonal actors, diet, unwanted pregnancy, and psychology.

‘A pinch of unseen, unguarded dust’: The World and Self in Thomas Hardy's Poems

2018 ◽  
Vol 8 (1) ◽  
pp. 49-66
Author(s):  
Monika Szuba
Keyword(s):  
The Body ◽  
The Self ◽  
Phenomenological Philosophy ◽  
The Earth ◽  
The World ◽  
The Universe ◽  
Recurrent Theme ◽  
Body Subject

The essay discusses selected poems from Thomas Hardy's vast body of poetry, focusing on representations of the self and the world. Employing Maurice Merleau-Ponty's concepts such as the body-subject, wild being, flesh, and reversibility, the essay offers an analysis of Hardy's poems in the light of phenomenological philosophy. It argues that far from demonstrating ‘cosmic indifference’, Hardy's poetry offers a sympathetic vision of interrelations governing the universe. The attunement with voices of the Earth foregrounded in the poems enables the self's entanglement in the flesh of the world, a chiasmatic intertwining of beings inserted between the leaves of the world. The relation of the self with the world is established through the act of perception, mainly visual and aural, when the body becomes intertwined with the world, thus resulting in a powerful welding. Such moments of vision are brief and elusive, which enhances a sense of transitoriness, and, yet, they are also timeless as the self becomes immersed in the experience. As time is a recurrent theme in Hardy's poetry, this essay discusses it in the context of dwelling, the provisionality of which is demonstrated in the prevalent sense of temporality, marked by seasons and birdsong, which underline the rhythms of the world.

An ayurvedic tablet formulation for ulcer protection

2020 ◽  
Vol 10 (4) ◽  
pp. 35-38
Author(s):  
Shiva Kumar K ◽  
Purushothaman M ◽  
Soujanya H ◽  
Jagadeeshwari S
Keyword(s):  
Pharmacological Activity ◽  
The Body ◽  
Gastric Ulcers ◽  
Antiulcer Activity ◽  
Herbal Drugs ◽  
Human Beings ◽  
Synthetic Drugs ◽  
Scientific Investigations ◽  
System A ◽  
The World

Gastric ulcers or the peptic ulcer is the primary disease that affects the gastrointestinal system. A large extent of the population in the world are suffering from the disease, and the age group of people those who suffer from ulcers are 20-55years. Herbs are known to the human beings that are useful in the treatment of diseases, and there are a lot of scientific investigations that prove the pharmacological activity of herbal drugs. Practitioners have been using the herbal material to treat the ulcers successfully, and the same had been reported scientifically. Numerous publications have been made that proves the antiulcer activity of the plants around the world. The tablets were investigated for the antiulcer activity in two doses 200 and 400mg/kg in albino Wistar rats in the artificial ulcer those are induced by the ethanol. The prepared tablets showed a better activity compared to the standard synthetic drug and the marketed ayurvedic formulation. The tablets showed a dose-dependent activity in ulcer prevention and treatment. Many synthetic drugs are available for the ulcer treatment, and the drugs pose the other problems in the body by showing the side effects and some other reactions. This limits the use of synthetic drugs to treat ulcers effectively. Herbs are known to the human beings that are useful in the treatment of diseases, and there are a lot of scientific investigations that prove the pharmacological activity of herbal drugs.

Nutritional Recommendation for COVID-19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 753-757
Author(s):  
Anagha Gulhane ◽  
Shamli Hiware
Keyword(s):  
Immune System ◽  
Global Health ◽  
Infectious Diseases ◽  
Immune Function ◽  
The Body ◽  
Health Issue ◽  
System Quality ◽  
Life Phase ◽  
Global Health Issue ◽  
Nutritional Recommendation

It is the most unreliable truth that anybody can get infected by the COVID-19, and nobody can escape from the danger of getting tainted by the virus. Yet, the line of hope is that anyone and everyone can boost their resistance, thus avoid the risk of getting affected by the illness. The immunity of humans pulls down as they grow older. If their immune system is robust, them falling sick is feeble. If their resistance is weak, them getting ill is sound. Several factors affect the immune system and its ability, including its nourishment. A two-way connection between nutrition, infection and immunity presents. Changes in one part will affect the others part in our body that's the nature's rule. Well defined immune system quality which is present between each life phase may influence the type, generality and the degree of infections. At the same time, low nutrition to the body will decrease the immune function and expose the body to the danger of getting infected by infectious diseases. Different quantity of micronutrients is required for increasing the immunity power of our body. Generally the vitamins A,C,D,E,B2,B6,B12, iron, zinc and selenium.The deficiencies of micronutrients are acknowledged as a global health issue, and also low nutrition makes it prone to establishes the infections in the body.

Myriad Aspects of Secular Thinking on Malayali Cuisine

GIS Business ◽  
2019 ◽  
Vol 14 (3) ◽  
pp. 202-206
Author(s):  
SAJITHA M
Keyword(s):  
Social Status ◽  
Daily Life ◽  
Social Indicators ◽  
The Body ◽  
Human Being ◽  
Healthy Life ◽  
The Social ◽  
The World ◽  
History Of ◽  
Civilized Society

Food is one of the main requirements of human being. It is flattering for the preservation of wellbeing and nourishment of the body.  The food of a society exposes its custom, prosperity, status, habits as well as it help to develop a culture. Food is one of the most important social indicators of a society. History of food carries a dynamic character in the socio- economic, political, and cultural realm of a society. The food is one of the obligatory components in our daily life. It occupied an obvious atmosphere for the augmentation of healthy life and anticipation against the diseases.  The food also shows a significant character in establishing cultural distinctiveness, and it reflects who we are. Food also reflected as the symbol of individuality, generosity, social status and religious believes etc in a civilized society. Food is not a discriminating aspect. It is the part of a culture, habits, addiction, and identity of a civilization.Food plays a symbolic role in the social activities the world over. It’s a universal sign of hospitality.[1]

Differenzierungen im Begriff, Gegenwart‘ bei Husserl und Merleau-Ponty

2017 ◽  
Vol 2017 (1) ◽  
pp. 39-54
Author(s):  
Jörg Zimmer
Keyword(s):  
Modern Philosophy ◽  
The Body ◽  
Fundamental Concept ◽  
Phenomenological Description ◽  
Philosophy Of Time ◽  
Phenomenology Of Perception ◽  
The World ◽  
Classical Philosophy ◽  
The Moment ◽  
Empty Time

In classical philosophy of time, present time mainly has been considered in its fleetingness: it is transition, in the Platonic meaning of the sudden or in the Aristotelian sense of discreet moment and isolated intensity that escapes possible perception. Through the idea of subjective constitution of time, Husserl’s phenomenology tries to spread the moment. He transcends the idea of linear and empty time in modern philosophy. Phenomenological description of time experience analyses the filled character of the moment that can be detained in the performance of consciousness. As a consequence of the temporality of consciousness, he nevertheless remains in the temporal conception of presence. The phenomenology of Merleau-Ponty, however, is able to grasp the spacial meaning of presence. In his perspective of a phenomenology of perception, presence can be understood as a space surrounding the body, as a field of present things given in perception. Merleau-Ponty recovers the ancient sense of ‘praesentia’ as a fundamental concept of being in the world.

Unmaking and Remaking the World in Long-Term Solitary Confinement

2018 ◽  
Vol 1 (1) ◽  
pp. 16
Author(s):  
Lisa Guenther
Keyword(s):  
The Body ◽  
Solitary Confinement ◽  
Hunger Strike ◽  
State Prison ◽  
Legal Documents ◽  
The Social ◽  
The World ◽  
Collective Resistance ◽  
Civil Death

In The Body in Pain, Elaine Scarry analyzes the structure of torture as an unmaking of the world in which the tools that ought to support a person’s embodied capacities are used as weapons to break them down. The Security Housing Unit (SHU) of California’s Pelican Bay State Prison functions as a weaponized architecture of torture in precisely this sense; but in recent years, prisoners in the Pelican Bay Short Corridor have re-purposed this weaponized architecture as a tool for remaking the world through collective resistance. This resistance took the form of a hunger strike in which prisoners exposed themselves to the possibility of biological death in order to contest the social and civil death of solitary confinement. By collectively refusing food, and by articulating the meaning and motivation of this refusal in articles, interviews, artwork, and legal documents, prisoners reclaimed and expanded their perceptual, cognitive, and expressive capacities for world-making, even in a space of systematic torture.

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