Medical aspects of the pregnant women with cervical insufficiency and infertility in anamnesis

2020 ◽  
pp. 48-50
Author(s):  
O.M. Perkhulyn ◽  
Keyword(s):  
Pregnant Women ◽  
Reproductive System ◽  
Reproductive Technologies ◽  
Overweight And Obesity ◽  
Reproductive Age ◽  
High Rate ◽  
Control Group ◽  
Cervical Insufficiency ◽  
Basic Group ◽  
Anovulatory Infertility

The formation of the puberty period is an important background for the female reproductive system in the future and the realization of the childbirth. The objective: to assess medical aspects in women with cervical insufficiency (CI) and infertility associated with anovulation in history. Materials and methods. 60 pregnant women with CI and anovulatory infertility in anamnesis formed the basic group. In these persons the pregnancy occurred after the use of additional reproductive technologies. The control group formed 30 pregnant women without CI and infertility and with physiological pregnancy. Results. In 33.33% individuals in the basic group menarche started in 16 years old and more. While in the control group in all women menarche started in 11–15 years old (χ2=11.00; p<0.001). In the reproductive age all controls (100.00%) had regular menstrual cycle that was in 3.33 times more than the women in the basic group (30.00%; χ2=36.61; p<0.001), 70.00% persons in the basic group had irregular menstruations. The menstruations were always irregular from menarche in 16.64% persons with CI vs none cases among healthy women (χ2=4.06; p=0.04). Endometriosis was diagnosed in 48.33% individuals with CI and infertility, polycystic ovary syndrome – 38.33%, diminished ovarian reserve – 26.67%, hyperandrogenism – 41.67%, ovary cyst – 20.00%. The rate of the infections of the low genital tract before pregnancy was higher in women in the basic group, also 45.00% of these women had gynecological operations (χ2=19.43; p<0.001); thyroid diseases – 25.00% (χ2=5.03; p=0.02), overweight and obesity – 26.67%. Conclusion. Thus, the results of our study indicate that in the persons with cervical infertility and anovulatory infertility in anamnesis disorders in the reproductive system mostly start from the puberty period; the high rate of gynecological diseases, operations on the pelvic organs, pregnancy loss are typical for them. Key words: infertility, cervical insufficiency, factors.

scholarly journals Assessment of the health status of infants born from women of the late reproductive period

2021 ◽  
Vol 66 (3) ◽  
pp. 128-133
Author(s):  
Kh. M. Omarova ◽  
E. S.-А. Ibragimova ◽  
T. Kh.-M. Khashaeva ◽  
I. Kh. Magomedova ◽  
R. G. Omarova ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Assisted Reproductive Technologies ◽  
Neurological Diseases ◽  
Perinatal Outcomes ◽  
Reproductive Technologies ◽  
Reproductive Period ◽  
Reproductive Age ◽  
Control Group ◽  
Age Related ◽  
Group I

Objective. To assess the condition of newborns from women of the late reproductive period (LRP), depending on the parity of births.Material and methods. The authors examined 130 pregnant women and their 130 newborns. Group I consisted of 60 primiparous women of late reproductive period and their 60 newborns, Group II included 40 multiparous women of the late reproductive period and their 40 newborns, Group III (control group) consisted of 30 healthy pregnant women aged from 18 to 25 years and their 30 newborns. The authors performed a retrospective analysis of the gestation course and perinatal outcomes. Ultrasound and neurosonography were used among the instrumental research methods.Results. Women of the late reproductive period gave birth to children in a state of asphyxia twice more often, who develop neurological disorders 1,5 times more often and complex postnatal adaptation and disorders of the perinatal period are twice more likely. Among women of the late reproductive period, primiparous women gave birth to children with the most severe disorders.Conclusion. The high incidence of neurological diseases in children born from women of the late reproductive period is associated with age-related changes in their germ cells, the implementation of assisted reproductive technologies, and the intake of hormonal drugs in early pregnancy. The data obtained should be taken into account by obstetricians in the course of pregnancy in women of late reproductive age; they should be included in the group of high risk of developing neurological disorders in children.

scholarly journals Lifestyle Intervention for Overweight/Obese Pregnant Women with Polycystic Ovarian Syndrome: Lessons and Challenges

Obesity Facts ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 405-414
Author(s):  
Cheng Liu ◽  
Lirui Zhang ◽  
Wei Zheng ◽  
Xin Liang ◽  
Li Zhang ◽  
...  
Keyword(s):  
Weight Gain ◽  
Pregnant Women ◽  
Lifestyle Intervention ◽  
Intervention Group ◽  
Perinatal Outcomes ◽  
Overweight And Obesity ◽  
Reproductive Age ◽  
Control Group ◽  
Good Compliance ◽  
Diet And Exercise

<b><i>Introduction and Objective:</i></b> Polycystic ovary syndrome (PCOS) is the most common reproductive disorder in women of reproductive age, and overweight and obesity are highly prevalent in women with PCOS. This study aims to explore whether lifestyle intervention can improve gestational weight gain (GWG), glucolipid metabolism, and perinatal outcomes in overweight/obese pregnant women with PCOS. <b><i>Methods:</i></b> This study is a randomized controlled trial that included overweight and obese pregnant women with PCOS who met the inclusion criteria of 8–12 gestational weeks. They were randomly allocated to the intervention group and the control group. Women in the intervention group were given individualized counseling on diet and exercise from a trained dietitian and followed up regularly by a trained dietitian. Women in the control group received guidance on diet and exercise in the form of group education. <b><i>Results:</i></b> A total of 296 pregnant women were enrolled in the study, including 164 in the intervention group and 132 in the control group. GWG was 11.93 ± 5.67 kg in the intervention group and 11.86 ± 5.35 kg in the control group and did not differ between the 2 groups. According to the per-protocol analyses, women with good compliance had a lower weight gain (10.11 ± 5.56 vs. 12.70 ± 5.31, <i>p</i> = 0.0042). The incidence of gestational diabetes mellitus and other perinatal outcomes did not differ between the 2 groups. For the lipid profile, we did not find significant improvement in the intervention group. <b><i>Conclusions:</i></b> Our study showed that lifestyle intervention of diet and exercise did not affect GWG, glucolipid metabolism, and perinatal outcomes of overweight/obese pregnant women with PCOS. However, women with good compliance can benefit from the lifestyle intervention for GWG. We believe that future studies should focus on trial design and increasing compliance to improve the quality of the study.

scholarly journals EVALUATION OF HORMONAL ASPECTS BY CERVICAL INSUFFICIENCY IN WOMEN WITH HISTORY OF INFERTILITY

2020 ◽  
Vol 20 (2) ◽  
pp. 76-79
Author(s):  
O.M. Perkhulyn
Keyword(s):  
Blood Serum ◽  
Pregnant Women ◽  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Main Group ◽  
The Body ◽  
Control Group ◽  
Cervical Insufficiency ◽  
The Past ◽  
History Of

Introduction. Today, the frequency of infertility is increasing worldwide. Infertility, associated with anovulation, is especially challenging for the medical correction especially. The leading aspect of this problem is hormonal disorders in the body of a woman. The aim of this study was to assess the level of estradiol and progesterone in the blood serum of pregnant women with cervical insufficiency and infertility associated with anovulation in the history. Materials and methods. The main group included 30 pregnant women with the II trimester of pregnancy, who had cervical insufficiency and infertility associated with anovulation in the past medical history. They got pregnant after assisted reproductive technologies. The control group included 30 pregnant women without cervical insufficiency and with physiological gestation. Estradiol and progesterone levels in blood serum were determined at 20-22 and 30-32 weeks of gestation. Results. The average age of the women in the basic group was statistically higher relative to the control one – 31.30±1.16 and 27.30±0.92 years, respectively (p=0.02). There was no difference in the number of pregnancies in women between both groups. In the main group, 73.33% of the persons were primagravida, 10.00 % of patients had two pregnancies, and 16.67 % - three pregnancies. 56.67 % of the women in the control group were primagravida, 26.67 % had two pregnancies, 16.66 % - three pregnancies. Although primaparas predominated in both groups, the number of such women was in 1.47 times higher in the main group (93.33 %) than in control (63.33 % of patients; χ2=6.28, p=0.01); 6.67 % and 26.67 % women had two labors respectively and 10.00 % of healthy patients - three labors. The concentration of estradiol at the 20-22 and 30-32 weeks of pregnancy in women of the main group almost corresponded to physiological parameters. However, the progesterone level in women with cervical insufficiency and a history of infertility was by 13.44 % lower than in healthy pregnant women at 20-22 weeks, and by 17.02% at 30-32 weeks (p=0.003). Conclusions. In pregnant women with cervical insufficiency and infertility associated with anovulation, the level of estradiol in the II and III trimesters of gestation mainly corresponds to the level of physiological pregnancy. However, they have the decrease in progesterone concentration in the III trimester of pregnancy relative to healthy pregnant women (p<0.003).

Optimisation of tactics of conducting pregnancy and labours at women after auxiliary reproductive technologies

2016 ◽  
pp. 160-164
Author(s):  
D.N. Maslo ◽  
Keyword(s):  
Pregnant Women ◽  
Resistance Index ◽  
First Trimester ◽  
Reproductive Technologies ◽  
Premature Delivery ◽  
Control Group ◽  
Uterine Arteries ◽  
Placental Dysfunction ◽  
Placental Blood ◽  
Two Stages

The objective: frequency decrease perinatal pathologies at women after ART on the basis of studying clinical-ehografical, endocrinological, biochemical, dopplerometrical, cardiotokografical and morphological researches, and also improvement of algorithm of diagnostic and treatment-and-prophylactic actions. Patients and methods. The work basis is made spent by us from 2012 on 2015 by complex inspection of 300 pregnant women from which 250 were after ART and 50 – firstlabours which pragnency without ART, and also their newborns. For the decision of an object in view of research spent to two stages. At 1 stage spent prosperctive research which included 150 pregnant women: з them 100 women pregnancy at which has come out ART (1 group) and 50 healthy women (control group). At 2 stage spent prospective randomization in which result of patients after ART have divided on two equal groups by therapy principle: 2 basic group - 75 pregnant women after ART at which used the algorithm improved by us; 3 group of comparison - 75 pregnant women after ART which have been spent on the standard treatment-and-prophylactic actions. Results. The results suggest that women after using ART is a high frequency of reproductive losses in the first trimester (10.0%), 3.0% of spontaneous abortion from 16 to 22 weeks, and 3.0% "early" premature delivery (22 to 28 weeks of pregnancy). The frequency of violations of the functional state of placenta in women after using IVF is 63.0%, which is the main cause of high levels of perinatal losses (40.0 ‰), and delivery by cesarean section (96.0%). Placental dysfunction in women after using ART characterized by retrohorialnyh hematoma (21.0%); size mismatch fruit (30.0%) and hypertonicity of the uterus (73.0%) against changes in fruit-placental blood flow - increased resistance index in umbilical artery and increased vascular resistance in the uterine arteries. Endocrinological and biochemical changes in placental dysfunction in women after using IVF starting from 28 weeks of pregnancy and are in significant reduction in progesterone, placental b1-microglobulin, B2-microglobulin of fertility and trophic в-glycoprotein. Conclusion. The received results: use of the algorithm of diagnostic and treatment-and-prophylactic actions improved by us allows to lower frequency of spontaneous interruption of pregnancy till 22 weeks – from 13.0% to 5.7%; «early» premature birth – from 3.0% to 1.0%; placentary dysfunction from 63.0% to 40.6%; cesarean sections – from 96.0% to 56.5%, and also perinatal losses – from 40.0‰ to 16.2‰. Key words: pregnancy, childbirth, auxiliary reproductive technologies.

scholarly journals A multilevel analysis of overweight and obesity among non-pregnant women of reproductive age in Malawi: evidence from the 2015–16 Malawi Demographic and Health Survey

2018 ◽  
Vol 11 (6) ◽  
pp. 496-506 ◽  
Author(s):  
Peter Austin Morton Ntenda ◽  
Jane Flora Kazambwe
Keyword(s):  
Pregnant Women ◽  
Health Survey ◽  
Media Coverage ◽  
White Collar ◽  
Overweight And Obesity ◽  
Demographic And Health Survey ◽  
Community Level ◽  
Reproductive Age ◽  
The Individual ◽  
Maternal Overweight

Abstract Background Overweight and obesity are well-known risk factors for non-communicable diseases such as cardiovascular disease, diabetes, some cancers and musculoskeletal disorders. In Malawi, the proportion of women who are overweight/obese has doubled, from 10% in 1992 to 21% in 2015–16. Therefore we aimed to explore the individual- and community-level factors associated with overweight and obesity among non-pregnant women of child-bearing age. Methods Secondary analysis of the 2015–16 Malawi Demographic and Health Survey was conducted. Overweight was defined as a body mass index (BMI) of 25 to &lt;30 kg/m2, while obesity was defined as a BMI ≥30 kg/m2. Two-level multilevel multivariable logistic regression models were constructed using a logit-link function with a binomial distribution on 7326 women living in 850 different communities. Results At the individual level, the adjusted multilevel regression results showed that women 15–19 y of age as well as women from the poorest households had reduced odds of being overweight/obese. However, women with white collar jobs and women who were affiliated with the Church of Central Africa Presbyterian and the Roman Catholic church had increased odds of being overweight/obese. At the community level, women from urban areas and women who resided in communities with a low percentage of media exposure had increased odds of being overweight or obese. While women from poor communities had reduced odds of being overweight and obese, the proportion change in variance showed that 56, 77 and 78% of total variations in the odds of overweight, obese and overweight/obese across the communities were explained by both individual- and community-level factors. The median odds ratio showed that the likelihood of maternal overweight, obese and overweight/obese increased by 63, 39 and 84% when the women moved from low- to high-risk neighbourhoods. Conclusions Older women, Christian women, women with white collar jobs and women from the richest households should be targeted during policy formulation. At the community level, media coverage should be spread evenly so that health awareness messages, consequences and means of overweight and obesity prevention are getting to the targeted women. Our study revealed evidence of clustering effects of overweight and obesity at the community level, hence neighbourhood variations with respect to maternal overweight and obesity should be taken into account when designing nutritional policies.

scholarly journals Modern view on the problem of optimization of therapy in pregnant women with functional cervical insufficiency

2018 ◽  
Vol 22 (1) ◽  
pp. 173-177
Author(s):  
V. F. Oleshko
Keyword(s):  
Blood Serum ◽  
Pregnant Women ◽  
Main Group ◽  
Control Group ◽  
Cervical Insufficiency ◽  
Progesterone Concentration ◽  
Therapeutic Dosage ◽  
Hormonal Balance ◽  
Magnesium Orotate ◽  
Micronized Progesterone

A functional cervical insufficiency plays an important role in the etiology of miscarriage and premature birth. The aim of research was to estimate the hormonal balance indexes during the course of pregnancy in pregnant women with functional cervical insufficiency and to correct the revealed violations in order to prevent obstetric complications. 101 pregnant women with confirmed diagnosis of a functional cervical insufficiency in term of gestation 22–32 weeks of pregnancy (the main group) and 34 pregnant women and women in labor with physiological condition of the cervix (the control group) were examined. The content of estradiol, progesterone, cortisol and prolactin was examined in the blood serum. On the second stage of examination 63 pregnant women obtained general basic therapy (I main group) and 38 pregnant women (II main group) received a developed treatment complex which included progesterone support by the micronized progesterone 200–400 mg twice a day up to 34–35 weeks of pregnancy, magnesium support by the magnesium orotate dehydrate in the therapeutic dosage and arginine glutamate in the therapeutic dosage. The correction of cervical insufficiency was performed with the help of a cervical pessary (according to indications). The examination of hormonal balance revealed an accurate decease of progesterone concentration on the background of high concentration of estradiol and increased levels of stress-associated hormones. Propitious influence of the developed therapy is proved by increase of progesterone concentration in the blood serum, normalization in stress-associated hormones balance according to gestational age. All this provideded the decrease of specific weight of threatened preterm labors, placental dysfunction, vaginitis, bacterial vaginosis and delay the labors up to 38–39 weeks of gestation in 97,4% of pregnant women (82,5% in the I main group). Prescription of micronized progesterone, magnesium orotate dehydrate, arginine glutamate to pregnant women with a cervical insufficiency is reasonable and effective one comparing with general and traditional therapy.

scholarly journals Pengaruh PemberianTablet Besi Pada Ibu Nifas Terhadap Anemia Post Partum Di Wilayah Puskesmas Pegandon

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Sri Rahayu
Keyword(s):  
Pregnant Women ◽  
Post Partum ◽  
Reproductive Age ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Kolmogorov Smirnov ◽  
Postpartum Mothers ◽  
Test Control

Abtrak. Anemia merupakan masalah kesehatan masyarakat secara global baik dinegara berkembang maupun negara maju. Anemia terjadi pada semua tahap siklus kehidupan, umumnya terjadi pada masa anak-anak dan wanita hamil (WHO, 2008). Di puskesmas Pegandon Kabupaten Kendal pada bulan Agustus 2017 didapatkan ibu hamil dengan kadar HB 8,2 gr% mengalami perdarahan pada saat melahirkan. Penelitian ini bertujuan mengevaluasi pemberian tablet FEpada ibu nifas.Desain penelitian menggunakanmatching pretest-post test control group design. Penelitian ini menggunakan data kohort dari ibu hamil  di puskesmas Pegandon yang melahirkan pada bulan Desember 2017 – Januari 2018. Sampelnya ibu nifas pada bulan  Januari – Maret 2018yang datang di puskesmas Pegandon untuk melahirkan sebanyak 72 ibu nifas. Hasil penelitian menunjukkan sebagian besar  pada responden perlakuan mempunyai usia reproduksi 30 (83,3%),  sebagian berpendidikan (SD danSMP) 28 (77.8%) dan berpenghasilan sesuai UMK 22 (61.1%) sedangkan pada responden control untuk usia reproduksi25 (69%), berpendidikan (SD dan SMP) 31 (86%) dan berpenghasilan sesuai UMK 15 (41.7%).Pada analisis bivariate dengan uji kolmogorov-smirnov didapatkan p> 0.00 pada perlakuan dan kontrol. Disimpulkan bahwa diberikan dan tidak diberikan tablet FE pada ibu nifas didapatkan hasil sama berpengaruh dalam peningkatan kadar HB.Disarankansetiap ibu nifas meminum tablet FE supaya tidak terjadi anemia dan memberikan ASI pada bayinya dengan maksimal.Kata kunci : anemia, ibu nifas, tablet FE The Influence Of Iron Tablets In Pifandon Mother To Post Partum Anemia In Pegandon Community Health Center Area Abtract.Anemia is a global public health problem both in developing and developed countries. Anemia occurs at all stages of the life cycle, generally occurring during childhood and pregnant women (WHO, 2008). In Pegandon Puskesmas Kendal Regency in August 2017 it was found that pregnant women with HB levels 8.2 gr% had bleeding at the time of delivery. This study aims to evaluate the administration of FE tablets to postpartum mothers. The study design used a matching pretest-post test control group design. This study uses cohort data from pregnant women at the Pegandon puskesmas who gave birth in December 2017 - January 2018. The sample was postpartum mothers in January - March 2018 who came to the Pegandon puskesmas to deliver 72 postpartum mothers. The results showed that most of the treatment respondents had a reproductive age of 30 (83.3%), some were educated (SD and SMP) 28 (77.8%) and earning according to MSE was 22 (61.1%) while the control respondents were for reproductive age 25 (69% ), educated (elementary and junior high) 31 (86%) and earning according to UMK 15 (41.7%). In the bivariate analysis with the Kolmogorov-Smirnov test, p> 0.00 was obtained for treatment and control. It was concluded that given and not given FE tablets to the puerperal mothers found the same effect had an effect on increasing HB levels. It is recommended that every puerperal woman take FE tablets so that anemia does not occur and give milk to her baby to the maximum..Keywords: anemia, puerperal mothers, FE tablets

scholarly journals Features of the morphological structure of the placenta in pregnant women with preeclampsia

2021 ◽  
pp. 10-15
Author(s):  
Volodymyr I. Chermak ◽  
Ihor I. Chermak ◽  
Chukwuanyinonso O. Ikeotuonye ◽  
Anatolii Ya. Senchuk
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
High Frequency ◽  
Morphological Changes ◽  
Morphological Structure ◽  
Morphological Features ◽  
Placental Insufficiency ◽  
Control Group ◽  
Basic Group ◽  
Adaptive Reactions

To study morphological features of the placenta in women in labor, pregnancy which complicated by preeclampsia we studied 26 placentae, of which 17 were from pregnant women with mild to moderate preeclampsia (basic group) and 9 from healthy women (control group). Histologically the study was conducted with methodically recommendations of T.D. Zadorozhnaya et al. for light microscopy. During the study of morphological features of the placenta in women in labor with preeclampsia were installed morphological changes in the placenta, which reflect a tendency to develop compensatory-adaptive reactions following their stress and exhaustion, which is a sign of placental insufficiency. Received data allow claiming a high frequency of development placental insufficiency in pregnant women with risk factors such as chronic salpingo-oophoritis, anemia, late preeclampsia, and inflammation diseases kidney.

scholarly journals Obesity in Pregnancy – Implications on Pregnancy Events

2020 ◽  
Vol 8 (B) ◽  
pp. 1157-1161
Author(s):  
Lilia Koleva ◽  
Victoria Spasova ◽  
Marieta Popova ◽  
Valentina Petkova ◽  
Milen Dimitrov
Keyword(s):  
Pregnant Women ◽  
Preterm Births ◽  
Developed Countries ◽  
Overweight And Obesity ◽  
University Hospital ◽  
Control Group ◽  
Case Group ◽  
Normal Limits ◽  
The University ◽  
Maternal Overweight

BACKGROUND: Overweight and obesity are serious health problems in most developed countries. The percentage of young women with excessive weight who get pregnant continues to grow every year. This raises a concern about the risks of the mother and the baby during pregnancy and after birth. AIM: This study aims to determine health risk for overweight mothers and especially the risk for preterm birth. MATERIALS AND METHODS: This is a prospective and retrospective study taking place in the outpatient clinic of the University Hospital “Maichin Dom”. Our study included 105 pregnant women with BMI ≥25 kg/m2 as a case group and 91 pregnant women with BMI within normal limits as a control group. RESULTS: Mean BMI in the case group was 34.79 ± 3.71 kg/m2 and 20.20 ± 2.24 kg/m2 in the control group. Among 105 women in the case group, we registered 24.8% (n = 26) who gave birth before term. Preterm births among 91 women in the control group were registered in 17.6% (n = 16) patients. We found a significant correlation between increased BMI and the risk of increased systolic and diastolic blood pressure. Moreover, we found comorbidities in 43.8% of cases and 24.2% of controls. CONCLUSION: Maternal overweight and obesity during pregnancy are associated with increased risks of preterm delivery and complications of pregnancy. Extra efforts should be made to help women lose weight before this important period of life.

scholarly journals Studies on Serum Total Cholesterol, in Second and Third Trimester of Pregnancy

1970 ◽  
Vol 1 ◽  
pp. 1-4 ◽  
Author(s):  
F Husain ◽  
SA Latif ◽  
MM Uddin
Keyword(s):  
Pregnant Women ◽  
Total Cholesterol ◽  
Serum Total Cholesterol ◽  
Reproductive Age ◽  
Control Group ◽  
Serum Concentrations ◽  
Third Trimester ◽  
Medical College ◽  
Unpaired Student

Study was carried out in the department of physiology, Mymensingh Medical College, Mymensingh, Bangladesh during the period of July 2006 to June 2007 to investigate the effect of pregnancy on serum total cholesterol. The serum concentrations of total cholesterol was measured in 100 cases of 2nd and 3rd trimester of pregnancy and in a control group of 100 cases of non pregnant women which was matched on reproductive age. Data were analyzed by computer with SPSS program using unpaired student‘t’ test. The results showed that the pregnant women had significantly higher concentrations of serum total cholesterol. Higher concentration of total cholesterol was more common in pregnant than control and reaching maximum at 3rd trimester of pregnancy. This may be a purely physiological response to pregnancy or it may be indicative of pathology in some women. These results deserve a follow up study to investigative whether the hypercholesterolemia persists after parturition. Key Words: Total cholesterol, pregnancy, parturition, hypercholesterolemia J Bangladesh Soc Physiol. 2006 Dec;(1):1-4.

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