scholarly journals The effect of canine disimpaction performed with temporary anchorage devices (TADs) before comprehensive orthodontic treatment to avoid root resorption of adjacent teeth

2016 ◽  
Vol 21 (2) ◽  
pp. 65-72 ◽  
Author(s):  
Farzin Heravi ◽  
Hooman Shafaee ◽  
Ali Forouzanfar ◽  
Seyed Hossein Hoseini Zarch ◽  
Mohsen Merati
Keyword(s):  
Side Effects ◽  
Root Resorption ◽  
Clinical Success ◽  
Clinical Success Rate ◽  
Control Group ◽  
Vas Score ◽  
Impacted Canines ◽  
End Of Treatment ◽  
Treatment Volume ◽  
Experimental Group

ABSTRACT Objective: The aim of this study was to evaluate the movement of impacted canines away from the roots of neighboring teeth before full-mouth bracket placement, performed by means of TADs to decrease undesired side effects on adjacent teeth. Methods: The study sample consisted of 34 palatally impacted canines, being 19 in the experimental group and 15 in the control group. In the experimental group, before placement of brackets, the impacted canine was erupted by means of miniscrews. In the control group, after initiation of comprehensive orthodontics, canine disimpaction was performed by means of a cantilever spring soldered to a palatal bar. At the end of treatment, volume of lateral incisors and canine root resorption were measured and compared by means of a CBCT-derived tridimensional model. Visual Analogue Scale (VAS) score, bleeding on probing (BOP) and gingival index (GI) were recorded. Clinical success rate was also calculated. Results: The volume of root resorption of lateral teeth in the control group was significantly greater than in the experimental group (p < 0.001). At the end of treatment, VAS score, GI and BOP were not significantly different between the two groups. Conclusion: Based on our results, it seems that disimpaction of canines and moving them to the arch can be done successfully carried out with minimal side effects by means of skeletal anchorage.

scholarly journals Optimal asymmetric thread for orthodontic microimplants: Laboratory and clinical evaluation

2014 ◽  
Vol 85 (4) ◽  
pp. 585-590 ◽  
Author(s):  
Raed H. Alrbata ◽  
Do-Won Ha ◽  
Wonjae Yu ◽  
Hee-Moon Kyung
Keyword(s):  
Clinical Success ◽  
Clinical Success Rate ◽  
Insertion Time ◽  
Control Group ◽  
Insertion Torque ◽  
Artificial Bone ◽  
Control Groups ◽  
Clinical Conditions ◽  
And Control ◽  
Experimental Group

ABSTRACT Objectives:  To investigate the performance of microimplants incorporating a newly designed asymmetric thread. Materials and Methods:  Three microimplants were compared. The control group comprised microimplants with the original v-shaped thread. The two experimental groups (Taper 1.0 and Taper 1.25) comprised prototype microimplants constructed with the new asymmetric thread; the Taper 1.25 specimens had a 1.25-mm-long and sharper tip, while the Taper 1.0 and control groups had a less sharp 1-mm tip. Two specially designed artificial bone blocks mimicking soft (maxillary) and hard (mandibular) bone were used to evaluate the microimplant insertion characteristics and postinsertion lateral stability. The peak insertion torque, insertion time, Periotest value (PTV), and torsional strength were measured. Then the microimplants were evaluated clinically over a 3-month period. Results:  Significant differences in peak insertion torque, insertion time, and PTV were observed and favored the experimental groups. Although statistically insignificant, the clinical success rate was also higher in the Taper 1.25 experimental group than in the control group (87.2% vs 75.6%). Conclusions:  The better performances of the experimental microimplant, under both laboratory and clinical conditions (although statistically insignificant in the latter), demonstrate the superiority of the new asymmetric thread.

Endovenous radiofrequency powered segmental thermal ablation (Closure FAST) of great saphenous veins

Phlebologie ◽  
2010 ◽  
Vol 39 (02) ◽  
pp. 69-71 ◽  
Author(s):  
T. M. Proebstle ◽  
Keyword(s):  
Side Effects ◽  
Thermal Ablation ◽  
Clinical Success ◽  
Clinical Success Rate ◽  
Duplex Ultrasound ◽  
Multicenter Trial ◽  
Saphenous Veins ◽  
Clinical Control ◽  
Prospective Multicenter Trial

Summary Background: Radiofrequency powered segmental thermal ablation Closure FAST has become a globally engaged technology for ablation of incompetent great saphenous veins (GSVs). Mid-term results of slowly resolving side effects are still not described. Methods: RSTA-treated GSVs (n = 295) were followed for 24 months in a prospective multicenter trial. Clinical control visits included flow and reflux analysis by duplex-ultrasound and assessment of treatment related side effects at all times. Results: 280 of 295 treated GSVs (94.9%) were available for 24 months follow-up. According to the method of Kaplan and Meier at 24 months after the intervention 98.6% of treated legs remained free of clinically relevant axial reflux. The average VCSS score improved from 3.9 ± 2.1 at screening to 0.7 ± 1.2 at 24 months follow-up (p < 0.0001). While only 41.1% of patients were free of pain before treatment, at 24 months 99.3% reported no pain and 96.4% did not experience pain during the 12 months before. At 24 months n=3 legs showed pigmentation along the inner thigh and one leg showed study-treatment related paresthesia. Conclusion: Radiofrequency powered segmental thermal ablation Closure FAST showed a very moderate side-effect profile in conjunction with a high and durable clinical success rate.

Ferric sulfate as pulpotomy agent in primary teeth: twenty month clinical follow-up

2000 ◽  
Vol 24 (4) ◽  
pp. 269-272 ◽  
Author(s):  
Hamijeta Ibricevic ◽  
Qumasha Al-Jame
Keyword(s):  
Success Rate ◽  
Primary Teeth ◽  
Root Resorption ◽  
Clinical Success ◽  
Clinical Success Rate ◽  
Ferric Sulfate ◽  
Primary Molar ◽  
Molar Teeth ◽  
The Moment

Seventy primary molar teeth, carious exposed, symptom free, without any sign of root resorption in children aged from 3 to 6 years (main age 4.3yr) were treated with conventional pulpotomy procedures. Ferric sulfate 15.5% solution (applied for 15 second for 35 teeth) and formocresol solution (five minute procedure of Buckley's formula for next 35 teeth) have been used as pulpotomy agents. In both groups, pulp stumps were covered with zinc-oxide eugenol paste. Permanent restorations were stainless steel crowns. Clinical check up was every three-months and radiographic follow-up time was six and twenty months after treatment. Our results within this period revealed 100% clinical success rate in both groups. Radiographic success rate was in both groups 97.2%, while in 2.8% cases has shown internal root resorption. On the basis of these results, we can recommend ferric sulfate as a pulpotomy agent in primary teeth in substitution for formocresol at the moment.

THE APPLICATION OF STATISTICAL METHODS IN EVALUATING THE RESULTS OF CLINICAL FINDINGS OF THE DRUG BOVHUALONIDASE AZOXIMER IN CATS WITH UROLOGICAL DISEASES

2020 ◽  
pp. 212-218
Author(s):  
А. V. Nazarova ◽  
◽  
B. S. Semenov ◽  
Т. Sh. Kuznetsova ◽  
◽  
...  
Keyword(s):  
Relative Risk ◽  
Side Effects ◽  
Risk Reduction ◽  
Absolute Risk ◽  
Control Group ◽  
Control Groups ◽  
Saint Petersburg ◽  
Number Of Patients ◽  
And Control ◽  
Experimental Group

In the period from November 2018 to August 2020, we conducted a randomized blind placebo-controlled confirmatory clinical trial in parallel groups on the basis of network of veterinary clinics in Saint Petersburg and Saint Petersburg state university of veterinary medicine. The purpose of the study: to evaluate the effectiveness of Bovhualonidaze azoximer(BA) in patients subjected to surgical intervention on the urethra and bladder, to prevent postoperative complications and relapses of the underlying disease. The frequency of complications was taken as an indicator of effectiveness. 80 cats were evaluated according to the criteria for inclusion in the study, after evaluation and randomization, 53 patients (24 and 29 cats in the experimental and control groups, respectively) who had indications for surgery on the urethra and/or bladder were included in the study. After the withdrawal of some patients, 38 cats were analyzed (17 and 23 cats in the experimental and control groups, respectively). Animals in the experimental group received BA drugs in addition to conventional therapy, and animals in the control group received placebo. The rate of complications in the experimental group was 11.8 %, in the control group-61.9 %. The relative risk was 19.0 %, and the relative risk reduction was 80.9 %. The chance of developing complications in the animals of the experimental group is 12.2 times lower than in animals of the control group.. Absolute risk reduction — 50.1 %, and the number of patients to be treated — 2 patients. The confidence interval for the risk of side effects of BA drugs in cats was 0.0-10.1 %. Based on the results of our clinical study, we proved that the use of BA drugs is effective for preventing complications during surgical interventions on the urethra and bladder, and the risk of side effects when using BA drugs in cats is insignificant

A Clinical Study of Formocresol Pulpotomy versus Root Canal Therapy of Vital Primary Incisors

2008 ◽  
Vol 32 (3) ◽  
pp. 211-214 ◽  
Author(s):  
Naser Asl Aminabadi ◽  
Ramin Mostofi Zadeh Farahani ◽  
Esrafil Balayi Gajan
Keyword(s):  
Root Canal ◽  
Root Resorption ◽  
Clinical Success ◽  
Clinical Success Rate ◽  
Clinical Indication ◽  
Radiographic Evaluation ◽  
Spontaneous Pain ◽  
Pathologic Finding ◽  
Root Canal Therapy ◽  
The Difference

Objectives: Pulpotomy of primary incisors is a serious challenge due to the lack of a distinct boundary between the coronal and the radicular pulp and the inaccuracy of the clinical indication criteria. The aim of the present study is the clinical and radiographic evaluation of pulpotomy versus root canal therapy(RCT) of vital primary incisors. Study design: A total of 100 incisors in 50 patients (female: 27, male: 23)aged 3-4 years were allocated to formocresol pulpotomy (45 teeth) and RCT (46 teeth) using zinc oxideeugenol. The radiographic and clinical evaluation of treatment outcomes was performed at 12 and 24 months post-operatively. A history of spontaneous pain, missing restorations, recurrent caries, mobility and percussion sensitivity, parulis or fistula, erythema, and swelling were recorded. Data analysis was performed based on two sample proportional test. Results: The clinical success rate was 86.9% for pulpotomy and 95.6% for RCT (P&gt;0.05). The radiographic assessment exhibited no pathologic signs in 76.08% of pulpotomy group and 91.3% of RCT group and the difference was statistically significant (P&lt;0.05). The most common pathologic finding was periodontal widening followed by external/internal root resorption. Periapical radiolucency and fistula in pulpotomized teeth was significantly higher than in RCT-treated teeth(P&lt;0.05) Conclusions: It may be concluded that the root canal therapy of vital primary incisors may be efficiently substituted for the pulpotomy of these teeth.

Broad Spectrum Oral Amoxycillin* in Acute Respiratory Tract Infections

1984 ◽  
Vol 12 (3) ◽  
pp. 207-209
Author(s):  
S Kalachand
Keyword(s):  
Side Effects ◽  
Tract Infection ◽  
Clinical Outcome ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Clinical Success ◽  
Clinical Success Rate ◽  
Acute Respiratory Tract Infection ◽  
Treatment Side Effects ◽  
Tract Infections

The clinical outcome of 143 patients presenting with acute respiratory tract infection and treated with oral amoxycillin is described. A clinical success rate of 92% was observed after 1 week's therapy with only one patient deteriorating whilst on treatment. Side-effects were mild and limited to 7% of patients.

scholarly journals DYNAMICS OF CLINICAL AND BIOCHEMICAL INDICATORS OF BLOOD IN CORRECTION OF PAIN SYNDROME WITH "GABAPENTIN" AND "FLEXOPROFEN"

2021 ◽  
Vol 245 (1) ◽  
pp. 76-82
Author(s):  
S.D. Klyukin ◽  
◽  
V.V. Salautin ◽  
N.A. Pudovkin ◽  
S.E. Salautina ◽  
...  
Keyword(s):  
Sodium Chloride ◽  
Side Effects ◽  
Diagnostic Marker ◽  
Pain Syndrome ◽  
Optimal Dose ◽  
Control Group ◽  
Therapeutic Effectiveness ◽  
Clinical Indicators ◽  
Biochemical Indicators ◽  
Experimental Group

The aim of this work was to study the dynamics of clinical indicators biohimicheskogo serum carnivores in the relief of pain drugs, "Gabapentin" and "Flexiprobe». For the study, a control group and two experimental groups were formed on the principle of pairs of analogues of 34 animals (17 dogs and 17 cats) in each. Intact animals (n=34, dogs-17, cats-17) were intramuscularly adminis-tered the drug "Sodium chloride 0.9 %" at a dose of 1 ml/kg at intervals of 24 hours for 7 days. An-imals of the experimental groups with pain syndrome were treated according to the following scheme: in the first experimental group (n=34, dogs-17, cats-17), the drug "Gabapentin" was used orally or rectally as a drug for the correction of pain syndrome in a dose of 10-60 mg/kg at intervals of 24 hours for 7 days, the optimal dose was selected depending on the type and severity of pain. In the second experimental group (n=34, dogs-17 heads, cats-17 heads), the drug "Flexoprofen" was administered subcutaneously or intramuscularly at a dose of 2 mg/kg at intervals of 24 hours for 7 days to correct the pain syndrome. The diagnostic marker of pain syndrome is a violation of electro-lyte metabolism in the blood serum in dogs and cats, characterized by a significant increase in sodi-um levels from 138.2±3.7 mmol/l to 194 ±4.2 mmol/l and a decrease in calcium levels to 2.4±0.7 mmol/l in dogs and 2.3±0.8 mmol/l in cats. The maximum therapeutic effectiveness of drugs with the least number of side effects is achieved by multimodal use of the drugs "Gabapentin"and " Flexoprofen".

Effect of exercise during adjuvant chemotherapy for breast cancer.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. 6524-6524
Author(s):  
Barbara K Haas ◽  
Cynthia R. C. Osborne ◽  
Svetislava J. Vukelja ◽  
Jennifer Selman ◽  
Trevor Davis ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Peripheral Neuropathy ◽  
Side Effects ◽  
Outcome Measures ◽  
Treatment Plan ◽  
Exercise Program ◽  
Well Being ◽  
Control Group ◽  
Positive Effects ◽  
Experimental Group

6524 Background: In 2018, an estimated 266,120 women faced the challenge of living with breast cancer and approximately 40,920 died from their disease. Nearly 100% of these women experienced significant treatment related side effects that negatively impact quality of life (QOL). Exercise has repeatedly demonstrated to alleviate many of the side effects, improve QOL, and decrease cancer recurrence and mortality. In spite of this evidence, women do not maintain exercise during treatment for breast cancer. The purpose of this randomized controlled trial was to determine the effectiveness of exercising the day chemotherapy is administered on 1) the persistence with an exercise program, 2) side effects, and 3) QOL. Methods: Eligible women were randomly assigned to a control or experimental group. As part of their treatment plan, all participants were referred to one of 14 community-based exercise centers to exercise. Experimental group also exercised at one of two cancer centers each day chemotherapy was administered. Outcome measures include exercise retention and chemotherapy, completion; cancer-related fatigue, nausea/vomiting, peripheral neuropathy, weight gain, and QOL. Outcome measures were assessed prior to every second course of chemotherapy and 3- and 6-months post-chemotherapy. Results: 273 women with Stage I-III breast cancer receiving chemotherapy were enrolled in the study. The number of participants who withdrew from exercise was higher among those in the control group (n= 16; 12.4%) compared with those in the experimental group (n = 10; 6.9%). At cycle 5, those in the experimental group reported less motor peripheral neuropathy than those in the control group (p = .018) and higher physical well-being scores than those in the control group (p = .047). Conclusions: The highest impact of the intervention was on attrition from exercise. Since participants in both the control and experimental groups exercised throughout chemotherapy, it is not surprising that the groups performed comparably with regard to side effects and QOL. Given the positive effects exercise has demonstrated on persons receiving cancer treatment in numerous studies, having patients exercise in the cancer center on the day of chemotherapy is a significant step toward engaging persons receiving chemotherapy in an exercise program.

scholarly journals Effectiveness of evidence based regimen for medical abortion over conventional methods

2017 ◽  
Vol 6 (3) ◽  
pp. 881
Author(s):  
Anitha K. Gopal ◽  
Sajini B. Sajini B. ◽  
Ganamurali S. ◽  
Beena Kumari R.
Keyword(s):  
Side Effects ◽  
Medical Abortion ◽  
Termination Of Pregnancy ◽  
Control Group ◽  
Severe Bleeding ◽  
Evidence Based ◽  
Medical Termination Of Pregnancy ◽  
Medical Termination ◽  
Vaginal Misoprostol ◽  
Experimental Group

Background: Medical abortion is a means of medical termination of pregnancy by drugs alone. This can be done upto 63 days using mifepristone and misoprostol tablets. For the conventional method, patient has to come to the hospital 3 times. In our study we reduced the interval between the drugs there by reducing the number of hospital visits. The objectives were to study the reduction of induction abortion interval following administration of evidence based regimen and to compare the proportion of patients developing complications in both the groups.Methods: It was a comparative study conducted at Department of Obstetrics and Gynecology, Govermnent MedicalCollege Kottayam, Kerala, India from May 2015 to November 2015.Results: The mean induction abortion interval in experimental group was 14.3 hours and in control group, it was 60.4 hours which was found to be statistically significant. Only 3 patients (7%) of experimental group had side effects whereas 12 patients. (17.4%) had side effects in the control group. Major side effects encountered were severe abdominal pain and severe bleeding per vaginum. Evidence based  regimen consist of administration of mifepristone 200mg and vaginal misoprostol 600µg 6 hours later for termination of pregnancy up to 63 days could reduce the induction abortion interval by 46 hours and had less side effects.Conclusions: As it reduces the induction abortion Interval and complications we feel that the evidence based regimen for Medical Termination of Pregnancy is superior to the FDA approved regimen.

Effect of Calcium Phosphate Glass Scaffold with Chitosan Membrane on the Healing of Alveolar Bone in 1 Wall Intrabony Defect in the Beagle Dogs

2005 ◽  
Vol 284-286 ◽  
pp. 851-854 ◽  
Author(s):  
D.H. Min ◽  
M.J. Kim ◽  
J.H. Yun ◽  
C.S. Kim ◽  
Yong Keun Lee ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Alveolar Bone ◽  
Root Resorption ◽  
Control Group ◽  
Beagle Dogs ◽  
Chitosan Membrane ◽  
Group I ◽  
Group Ii ◽  
Histological Results ◽  
Experimental Group

This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium phosphate block bone with chitosan membrane on the regeneration of 1-wall intrabony defects in the beagle dogs. The surgical control group received a flap operation only, while the experimental group I was treated with a chitosan nonwoven membrane only and the experimental group II was treated with a chitosan nonwoven membrane and a calcium phosphate block bone. The subjects were sacrificed 12 weeks after surgery and a comparative histometric analysis was done. No root resorption or ankylosis were observed in the experimental group. Mann-Whitney U test showed that the experimental group II produced statistically significant higher gain in connective tissue adhesion, new cementum regeneration and new bone formation. Based on histological results, the calcium phosphate block bone successfully functioned as a osteoconductive scaffold for invading cells of host.

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