Reaction of lymphoidal organs of rats on the growth of glioma C6
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The study of the responce of peripheral lymphoid structures to the presence of malignant tumor in the brain offers the challenge for the use of immunotherapeutic approaches for the treatment of this disease. This work was aimed to evaluate weight indices and cellularity of lymphoid organs in rat with C6 glioma. One was found that the growth of glioma is accompanied by changes in the cellularity of the organs of the lymphatic system. The observed changes indicate the likelihood of the presentation of C6 glioma antigens in peripheral lymphoid structures, as well as the negative impact of glioma growth on thymus and spleen homeostasis.
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2021 ◽
Vol 118
(29)
◽
pp. e2108082118
2020 ◽
pp. 174-176
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