Determining the risk factors for xerostomia in dental out-patients

Aim. To determine the risk factors for xerostomia.Methods. The study included 137 patients aged 25 to 60 years (61 males, 76 females), the main group consisted of 40 patients with xerostomia (11 males, 29 females), with a median age of 44.5 years (38; 49.5). The control group included 97 patients without xerostomia (50 males, 47 females), median age - 42 years (36; 49). The questionnaire by V.V. Afanas’ev (1993) was used to collect the complaints, anamnesis and to determine the risk factors for xerostomia. Qualitative indicators are listed as absolute numbers and shares (%). In assessing the statistical significance of qualitative indicators differences, contingency tables with subsequent Pearson chi-square test were used.Results. Among the patients of the main group, 19 (47.5%) took medications decreasing the salivation, with intake period duration ranging from 1 to 4 months. When questioned, patients with xerostomia reported statistically significant increase in the rates of cardiovascular disorders (15 patients, 37.5%), gastrointestinal tract diseases (11 patients, 27.5%), endocrine diseases (10 patients, 25%), musculoskeletal diseases (9 patients, 22.5%). The combination of three or more positive answers on V.V. Afanas’ev questionnaire questions was revealed in 12 (30%) patients of the main group, which was significantly higher compared to the control group (1 patient, 1.03%).Conclusion. The most typical reasons for developing xerostomia were the following: taking medications decreasing the salivation, presence of cardiovascular, gastrointestinal, musculoskeletal and endocrine disorders. Three or more positive answers on V.V. Afanas’ev questionnaire questions increase the probability of detecting xerostomia in a respondent.

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Small dose of ephedrine for prevention of hypotension following propofol and fentanyl administration during induction of general anesthesia

Annals of African Medical Research ◽

10.4081/aamr.2020.126 ◽

2021 ◽

Vol 3 (2) ◽

Author(s):

Gamal Ejaimi ◽

Abla Saab ◽

Sittelnissa Ahmed ◽

Areeg Ahmed ◽

Hussain Abujamilah ◽

...

Keyword(s):

General Anesthesia ◽

Small Dose ◽

Elective Surgery ◽

Statistical Significance ◽

Control Group ◽

P Value ◽

Chi Square ◽

Arterial Blood ◽

Chi Square Test ◽

Study Participants

Induction of general anesthesia with propofol and fentanyl could result in hypotension and bradycardia. Various methods are being used to prevent these adverse effects. The aim of our study was to assess the efficacy and safety of a small dose of ephedrine in prevention of hypotension following administration of propofol and fentanyl. This prospective, randomized, comparative study was conducted among a total of 50 patients, both genders, age 18 years up to 60 years with ASA grade Ι and ΙΙ and some of class ΙΙΙ, presented for elective surgery under general anesthesia. Patients were randomly allocated into one of two groups (25 patients in each): CG (the control group), which received propofol in a dose of 2 mg/kg, intravenously, over 20–30 s mixed with 2 mL normal saline: and EphG (Ephedrine group), while received propofol in a dose of 2 mg/kg, intravenously, over 20–30 s mixed with 2 mL of ephedrine (10 mg). The Mean Arterial Blood Pressure (MAP) and Heart Rate (HR) were recorded before induction and then every 1 min up to 6 min after induction. The categorical data are presented as a number and percentage and were subjected to Fisher’s exact or Chi-square test for analysis. The statistical significance was p≤0.05. The significant differences in HR were observed in the 3rd,4th, and 5th minutes with P-value, 0.018, 0.000, 0.000, respectively. However, no patient in the study participants had bradycardia. The significant differences in MAP were observed in the 2nd, 3rd,4th, and 5th minutes with P-value, 0.035, 0.000, 0.000, and 0.000, respectively. The percentage of patient in CG who developed hypotension in the 3rd and 4th is 44% and 32% compared to 8% and 0% in EphG, with significant differences (P-value 0.004 and 0.002, respectively). Administration of small dose of ephedrine with propofol could attenuate propofol/fentanyl hypotensive and bradycardic effects.

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FAKTOR RISIKO KEPADATAN LALAT DAN SANITASI RUMAH DENGAN KEJADIAN DIARE DI KELURAHAN TANJUNG PINANG KOTA JAMBI TAHUN 2017

Jurnal Ilmiah Universitas Batanghari Jambi ◽

10.33087/jiubj.v18i1.449 ◽

2018 ◽

Vol 18 (1) ◽

pp. 208

Author(s):

Listautin Listautin

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Odds Ratio ◽

Protective Factor ◽

Health Department ◽

Bivariate Analysis ◽

Control Group ◽

Case Group ◽

Chi Square ◽

Chi Square Test

Diarrhea is one of health problem in the world including Indonesia. The Morbidity survey undertaken by Sub-Directorate of diarrhea, Health Department from 2007 to 2010is improved. According to the data gained from Puskesmas in Tanjung Pinang Jambi in 2017, it is found out that 5 different districs in Tanjung Pinang are the district which has the highest rate of diarrhea sufferers. The aim of this study is to find out the risk factors of the flies density and the dwelling sanitation to the occurance of diarrhea in Tanjung Pinang Jambi in 2017. This study is quantitative study by using case control design. The sample of this study is 68 people who consists of 34 samples of case group and 34 samples of control group. This study is analyzed through univariate and bivariate analysis by using chi-square test. The instruments of this study are the reviewed document, ceklist, and the measurement through fly grill. The result of analysis are found out that toilet is the main risk factor for the occurance of diarrhea with odds ratio (OR) value is 3,519. Sewerage (SPAL) is one the risk factor of the diarrhea occurance with odds ratio (OR) value is 3,361. The waste is the other risk factors for the occurance of diarrhea with odds ratio (OR) value is 4,418. The flies density is the protective factor for the diarrhea occurance with odds ratio (OR) value is 0,773.Based on the result of this study, it can be concluded that it is necesarry to do the coorporation across program to optimize the noticing of information to public concerning on the importance of good dwelling sanitation and the low flies density in order to avoid from the occurance of diarrhea.Keyword : Diarrhea, Dwelling Sanitation, Flies Density

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Index Analysis of Osteonecrosis and Related Causes

10.21203/rs.3.rs-68407/v1 ◽

2020 ◽

Author(s):

Tingting Liu ◽

Yuju Cao ◽

Huiqiang Wu ◽

Feimeng An ◽

Changxu Han ◽

...

Keyword(s):

Statistical Significance ◽

Population Sample ◽

Onset Time ◽

Categorical Variables ◽

Control Group ◽

Case Group ◽

Chi Square ◽

Chi Square Test ◽

The Relationship

Abstract Background: The pathogenesis of non-traumatic osteonecrosis of the femoral head (ONFH ) is related to the interruption of blood supply caused by lipid metabolism and hypercoagulability. The purpose of this study was to explore the relationship between clinical biochemical parameters and non-traumatic ONFH. Methods: The basic information and biochemical indexes of 1292 patients with non- traumatic ONFH and 1880 healthy controls were collected. SPSS software (version 22.0) was used to process and analyze the data. T-test was used for quantitative analysis. Chi-square test was used for categorical variables.p< 0.05 were the index with statistical significance. Results: In the population sample, TC (p= 0.00004), LDL (p= 0.014) and PLT (p= 0.000005) levels were statistically significant between the two groups.In men, levels of TC (p = 0.004), LDL (p= 0.011), and PLT (p= 0.00005) were statistically significant between the two groups.In women, TC (p= 0.001) and PLT (p= 0.048) levels were statistically significant between the two groups.There were differences in TC (p= 0.00001) and PLT (p= 0.031) levels between the case group and the control group in samples aged less than 45 years.There were differences in LDL (p= 0.00002) and PLT (p= 0.022) levels between the two groups in samples older than 45 years.Compared with the control group, patients with alcohol-induced ONFH had HDL (p = 0.002).LDL (p= 0.00002);The level of PLT (p= 0.0001) was significantly different.HDL (p = 0.005) was found in alcohol-induced ONFH patients younger than 45 years of age.The PLT level (p=0.045) was different from that of the control group.There was a difference in LDL (p= 0.000003) levels between control and alcohol-induced ONFH patients older than 45 years.The older the onset age, the TC in vivo;HDL;LDL;ApoA1;ApoB;The lower the PLT level.With the prolongation of the onset time, the PLT level in the patient's body is decreasing continuously.Conclusion: The changes of biochemical indexes are closely related to the occurrence of non-traumatic ONFH. Our research can provide a new direction for the prevention of ONFH.

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ANALISIS FAKTOR RISIKO YANG BERHUBUNGAN DENGAN KEJADIAN PLASENTA PREVIA

JURNAL KEDOKTERAN ◽

10.36679/kedokteran.v6i2.338 ◽

2021 ◽

Vol 6 (2) ◽

pp. 100

Author(s):

Nurul Huda Mursalim ◽

Saharuddin Saharuddin ◽

Azizah Nurdin ◽

Jelita Inayah Sari

Keyword(s):

Risk Factors ◽

Caesarean Section ◽

Pregnant Women ◽

Placenta Previa ◽

Case Control ◽

Control Group ◽

Chi Square ◽

Purposive Sampling ◽

Chi Square Test ◽

History Of

Tujuan penelitian ini adalah untuk mengetahui hubungan variabel dependen yaitu umur, paritas, riwayat sectio sesarea, riwayat gemelli dengan variabel independen yaitu plasenta previa di RSUD Batara Guru dan RS Hikmah Sejahtera Kabupaten Luwu Tahun 2018-2019. Pada studi ini memanfaatkan metode analitik observasional dengan pendekatan case control. Sampel ditentukan melalui perbandingan kelompok kasus sebanyak 50 sampel dengan kelompok kontrol 50 sampel. Teknik sampling menggunakan purposive sampling. Untuk mengetahui hubungan faktor risiko memanfaatkan uji chi square. Hasil terbanyak didapatkan 78 ibu hamil risiko rendah, 76 ibu hamil dengan multipara, ibu hamil dengan tidak ada riwayat sectio sesarea didapatkan 76 ibu hamil dan ibu yang tidak memiliki riwayat gemelli ada 97 ibu hamil. Hasil penelitian menujukkan dari uji chi square antara umur dengan plasenta previa didapatkan (P= 0.008 < 0,05) untuk hubungan paritas dengan plasenta previa didapatkan (P= 0,815 > 0,05) hubungan riwayat sectio sesarea didapatkan sebesar (P= 0.035 < 0,05) dan untuk hubungan riwayat gemelli sebesar (P= 1,000 > 0,05). Kesimpulan dari penelitian ini adalah tidak terdapat hubungan faktor risiko paritas, riwayat gemelli pada kejadian plasenta previa dan didapatkan hubungan faktor risiko antara umur, riwayat sectio sesarea dengan kejadian plasenta previa di RSUD Batara Guru dan RS Hikmah Sejahtera Kabupaten Luwu Tahun 2018-2019. Kata kunci: Umur, paritas, riwayat sectio sesarea, riwayat gemelli, plasenta previa ABSTRACTThe major objective of this study was to investigate the risk factors that affect the occurrences of placenta previa, such as ages, parity, caesarean section history, and gemelli history of pregnant women. This study was conducted at Batara Guru Hospital and Hikmah Sejahtera Hospital of Luwu Regency in 2018 to 2019. The methodological approach taken in this study was observational analytic by using a case control approach. The samples used in this research consisted of 50 samples for the case group and 50 samples for the control group. The sampling technique used was a purposive sampling. A chi square test was performed in this experiment in order to understand the risk factors. From this research, it was apparent that 78 pregnant women were with the low risk of getting placenta previa, 76 pregnant women were with multiparous, 76 pregnant women were with no history of cesarean section, and 79 pregnant women were without a gemelli history. Based on the chi square test, the results of this study indicated that various relationships were obtained such as the relationship between ages and placenta previa occurrences with (P = 0.008 <0.05), the correlation among parity and placenta previa occurrences with (P = 0.815> 0.05), the correlation among caesarean section history and placenta previa occurrences with (P = 0.035 <0,05), and the correlation among gemelli history and placenta previa occurrences with (P = 1,000> 0.05). This research concludes that there was no relationship between parity and gemelli history factors and the occurrences of placenta previa. In contrast, it was evident that there were close relationships between the ages and caesarean section history factors and the occurrences of placenta previa at Batara Guru Hospital and Hikmah Sejahtera Hospital of Luwu Regency in 2018 to 2019.Keywords: ages, parity, caesarean sectio history, gemelli history, placenta previa

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Prevalence and risk factors associated with serovars of Leptospira in dogs from Culiacan, Sinaloa

Veterinaria México OA ◽

10.21753/vmoa.4.2.369 ◽

2017 ◽

Vol 4 (2) ◽

Author(s):

Carlos Víctor Hernández Ramírez ◽

Soila Maribel Gaxiola Camacho ◽

Ignacio Osuna Ramirez ◽

Idalia Enríquez Verdugo ◽

Nohemí Castro del Campo ◽

...

Keyword(s):

Risk Factors ◽

Statistical Significance ◽

Epidemiological Survey ◽

Serum Samples ◽

Chi Square ◽

Factors Associated ◽

Epidemiological Risk ◽

Chi Square Test ◽

Sanitary Conditions ◽

The City

Veterinaria México OA ISSN: 2448-6760Cite this as:Hernández Ramírez CV, Gaxiola Camacho SM, Osuna Ramirez I, Enríquez Verdugo I, Castro del Campo N, López Moreno HS. Prevalence and risk factors associated with serovars of Leptospira in dogs from Culiacan, Sinaloa. Veterinaria México OA 2017;4(2).doi: 10.21753/vmoa.2.2.369Domestic dogs transmit Leptospira spp. to humans, and determining the health risk that they represent is of paramount importance. To determine the seroprevalence and main risk factors associated with serovars of Leptospira in dogs from Culiacan, Sinaloa, we obtained serum samples from 165 dogs. The samples were stored at -40 °C and were analysed by the microbiology laboratory at Centro Nacional de Sanidad Animal using the leptospirosis microscopic agglutination test. Additionally, a survey was performed to identify epidemiological risk factors, and statistical inference was determined using chi-square test, odd ratios, and logistic regression with a statistical significance set at P < 0.05. The prevalence of Leptospira was 9 % (15/165), and we identified seven serovars: canicola 17 (46 %), icterohaemorrhagiae (40 %), bratislava (40 %), grippotyphosa (33 %), shermani (33 %), pyrogenes (20 %) and ballum (13 %). Based on our epidemiological survey, the risk factors associated with the detection of antibodies against Leptospira include the permanent habitation of pets in courtyards (OR = 4.6, P < 0.05) and presence of water stored in drums and basins (OR = 3.25, P < 0.05). The prevalence of leptospirosis in dogs indicates that the disease is present in the city of Culiacan and that leptospiral antibodies in dogs increase in poor sanitary conditions with stored water, which increases the potential risk of infection for both humans and animals.Figure 1. Frequency of observed serovars of Leptospira

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Investigation on risk factors of haemorrhagic fever with renal syndrome (HFRS) in Xuancheng City in Anhui Province, Mainland China

Epidemiology and Infection ◽

10.1017/s0950268820002344 ◽

2020 ◽

Vol 148 ◽

Author(s):

Guangjian Wu ◽

Zhicai Xia ◽

Fengtian Wang ◽

Jiabing Wu ◽

Deman Cheng ◽

...

Keyword(s):

Risk Factors ◽

High Risk ◽

Statistical Significance ◽

Mainland China ◽

Multivariate Logistic Regression Analysis ◽

Health Concern ◽

Haemorrhagic Fever ◽

Chi Square ◽

Increased Risk ◽

Chi Square Test

Abstract Haemorrhagic fever with renal syndrome (HFRS), a rodent-borne disease, is a major public health concern in both developed and developing countries. China is the most severe endemic country in the world, constituting 90% of the cases. Although the incidence of HFRS has substantively decreased in most areas of China, HFRS has rebounded remarkably in some epidemic areas. Xuancheng is one of these areas. In this study, we collected the case data reported recently in Xuancheng and designed a 1:3 case−control study. The Chi-square test, univariate and multivariate logistic regression analysis were performed. In all cases, farmers made up the highest proportion of occupations. And there were 20 variables with statistical significance including indoor hygienic conditions; the surrounding environment; whether bitten by rats at work and other criteria. In addition, exposure to rodents and rats bites is a high-risk factor for HFRS. Rodent density was calculated at 20.9% (159/760), the virus carrier rate was 9.4% (15/159) and the index of rats with a virus was about 2.0%. Exposure to rodents and insect bites is also high-risk factors for HFRS among local residents in Xuancheng. More importantly, during the flood years, the increased density of rodents led to an increased risk of human exposure to rodents. As our statistical analysis proves, targeted strategies should be developed and implemented to reduce the incidence of local diseases in the future.

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Association of Kallikrein gene polymorphisms with sporadic intracranial aneurysms in the Chinese population

Journal of Neurosurgery ◽

10.3171/2013.11.jns131036 ◽

2014 ◽

Vol 120 (6) ◽

pp. 1397-1401 ◽

Cited By ~ 3

Author(s):

Miaomiao Suo ◽

Yahui Lin ◽

Hui Yu ◽

Weihua Song ◽

Kai Sun ◽

...

Keyword(s):

Risk Factors ◽

Gene Polymorphisms ◽

Chinese Population ◽

Intracranial Aneurysms ◽

Control Group ◽

Finnish Population ◽

Chinese Han ◽

Chi Square ◽

Han Ethnicity ◽

Chi Square Test

Object Variants of Kallikreins have been shown to be risk factors for intracranial aneurysm (IA) in a Finnish population. In the present study, the authors investigated the correlation between polymorphisms in the Kallikrein gene cluster and IAs in the Chinese population. Methods The association of Kallikrein variants (rs1722561 and rs1701946) with sporadic IAs was tested in 308 cases and 443 controls. The differences in allelic frequencies between patients and the control group were evaluated with the chi-square test. Results The C allele of rs1722561 showed a significant reduction in the risk of sporadic IA (OR 0.71, 95% CI 0.53–0.95; p = 0.023). However, no association of the variant rs1701946 with sporadic IA was found (OR 0.78, 95% CI 0.57–1.06; p = 0.115). Conclusions The variant rs1722561 of Kallikreins might reduce the risk of sporadic IAs among individuals of Chinese Han ethnicity. This study confirms the association between Kallikreins and IAs.

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Usporedba neonatalnog ishoda u majki s gestacijskim dijabetesom tijekom dva razdoblja

Collegium Antropologicum ◽

10.5671/ca.44.1.4 ◽

2020 ◽

Vol 44 (1) ◽

pp. 29-36

Author(s):

Ella Đukić ◽

Vesna Milas ◽

Marijana Arambašić ◽

Tihana Nađ ◽

Andrea Prutki ◽

...

Keyword(s):

Perinatal Outcome ◽

Statistical Significance ◽

Chronic Illnesses ◽

Control Group ◽

Chi Square ◽

Metabolic Complications ◽

Pregnancy And Childbirth ◽

Acute Conditions ◽

Chi Square Test ◽

Control Study

Gestational diabetes is one of the most common metabolic complications during pregnancy. Pregnant diabetic mothers, if not well regulated, are more often subject to a number of acute conditions and complications during pregnancy and childbirth. Hypoglycemia, hypocalcemia, hypertrophy, lower Apgar is often seen in children. This is a case control study. We compared mothers with GD and their infants to mothers without GD and their children both in 2015 and 2018 in order to determine whether there are any differences among them, and to compare the perinatal outcome of their infants. Examinees have been born in 2015 and 2018 (262) at KBC Osijek. The control group (262) was first neonates born after the examinees in 2015 and 2018. The results are shown in tables, with absolute and relative frequencies, and the significance of differences in the chi-square test with confidence interval at 95 %. Statistical significance will be accepted at p <0.05 level. Different acute conditions and other chronic illnesses are more common in mothers with GD. They have more complications during labor. Their infants are more often diagnosed with hypertrophy, hypoglycemia, and hypocalcemia. They also require more oxygen tratment, longer hospitalization and birth by C-section. In 2018, the number of hypoglycemic and hypocalcemic infants was twice lower, and children have been hospitalized much shorter. Better care for mothers during pregnancy and their glycemic control lead to significantly less complications in their infants and better perinatal outcome of such infants.

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Risk factors for clavicular midshaft fractures after hook plate fixation for the treatment of Neer type II clavicular fractures

Journal of International Medical Research ◽

10.1177/03000605211035898 ◽

2021 ◽

Vol 49 (8) ◽

pp. 030006052110358

Author(s):

Yihan Li ◽

Qingxian Tian ◽

Kunpeng Leng ◽

Meng Guo

Keyword(s):

Risk Factors ◽

Plate Fixation ◽

Advanced Age ◽

Hook Plate ◽

Control Group ◽

Type Ii ◽

Chi Square ◽

Included Patient ◽

Chi Square Test ◽

And Control

Objective Neer type II fractures are common, and hook plate fixation is one of the recommended treatments. Although clavicular midshaft fractures after hook plate fixation are rare, such fractures increase patients’ suffering and worsen their functional outcomes. This study was performed to identify the risk factors for this complication. Methods From 2009 to 2018, 425 patients were admitted with Neer type II clavicular fractures. According to the selection criteria, 352 patients were included in this retrospective observational study. All patients were divided into either the complications group (patients with midshaft fractures) or the control group (patients without midshaft fractures). Data collected included patient demographics and surgical, hook plate, and screw characteristics. The chi-square test was used to conduct between-group comparisons of risk factors. Statistically significant variables were included in a logistic regression model. Results In both the complications group (n = 21) and control group (n = 331), significantly more patients of advanced age and significantly more patients treated with hook plates that were not bent during surgery developed midshaft fractures. Conclusion The risk of a clavicular midshaft fracture after hook plate fixation may be significantly increased by advanced age or a lack of hook plate bending.

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Correlation of Metabolic Risk Factors with Sessile Serrated Lesions

Journal of Gastrointestinal and Liver Diseases ◽

10.15403/jgld-507 ◽

2020 ◽

Vol 29 (2) ◽

pp. 175-179

Author(s):

Melania Macarie ◽

Simona Bataga ◽

Simona Mocan ◽

Monica Pantea ◽

Razvan Opaschi ◽

...

Keyword(s):

Risk Factors ◽

Statistical Significance ◽

Interval Cancer ◽

Metabolic Risk Factors ◽

Control Group ◽

Anatomical Site ◽

Metabolic Risk ◽

Right Colon ◽

Serrated Lesions ◽

The Right

Background and Aims: The importance of sessile serrated lesions (SSLs) in the pathogenesis of colorectal carcinoma has been recently established. These are supposed to cause the so-called “interval cancer”, having a rapidly progressive growth and being difficult to detect and to obtain an endoscopic complete resection. We aimed to establish the most important metabolic risk factors for sessile serrated lesions. Methods: We performed a retrospective case-control study, on a series of 2918 consecutive patients who underwent colonoscopy in Gastroenterology and Endoscopy Unit, County Clinical Emergency Hospital, Târgu-Mureș, Romania between 1 st of January 2015-31 th of December 2017. In order to evaluate the metabolic risk factors for polyps’ development, enrolled participants were stratified in two groups, a study group, 33 patients with SSLs lesions, and a control group, 138 patients with adenomatous polyps, selected by systematic sampling for age and anatomical site. Independent variables investigated were: gender, smoking, alcohol consumption, obesity, arterial hypertension, diabetes, hypercholesterolemia, hypertriglyceridemia, hyperuricemia, nonalcoholic liver disease. Results: For SSLs the most common encountered localization was the right colon in 30.55% of cases. By comparative bivariate analysis between SSLs group and control group, it was observed that hypertension (p=0.03, OR 2.33, 95 %CI 1.03-5.24), obesity (p=0.03, OR 2.61, 95 %CI 1.08-6.30), hyperuricemia (p=0.04, OR 2.72, 95 %CI 1.28-7.55), high cholesterol (p=0.002, OR 3.42; 95 %CI 1.48-7.87), and high triglycerides level (p=0.0006, OR 5.75; 95 %CI 1.92-17.2) were statistically associated with SSLs development. By multivariate analysis hypertension and hypertriglyceridemia retained statistical significance. Conclusions: Our study showed that the highest prevalence of SSLs was in the right colon and hypertension and increased triglycerides levels were associated with the risk of SSLs development. These risk factors are easy to detect in clinical practice and may help identifying groups with high risk for colorectal cancer, where screening is recommended.

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