Clinical characteristics of alcoholism with different rates of progression

1985 ◽  
Vol 66 (6) ◽  
pp. 440-442
Author(s):  
D. D. Enikeeva
Keyword(s):  
Clinical Characteristics ◽  
Subsequent Development ◽  
Clinical Material ◽  
Personality Changes ◽  
Initial Stage ◽  
Rate Of Progression

In order to study the rate of progression of alcoholism, an analysis of a large clinical material was carried out: the timing of the appearance and subsequent development of the axial symptomatology of the disease, the duration of the stages and the rate of transition of the initial stage to the late ones, as well as the time of the onset of the consequences and complications of the disease, personality changes and social decompensation.

scholarly journals A Case of Frontotemporal Lobar Degeneration with Progressive Dysarthria

2006 ◽  
Vol 17 (2) ◽  
pp. 97-104 ◽  
Author(s):  
Nami Ihori ◽  
Shigeo Araki ◽  
Kenji Ishihara ◽  
Mitsuru Kawamura
Keyword(s):  
Clinical Symptoms ◽  
Frontotemporal Degeneration ◽  
Behavioral Abnormalities ◽  
Personality Changes ◽  
Initial Stage ◽  
Neuropsychological Characteristics ◽  
Opercular Syndrome ◽  
Rate Of Speech ◽  
Clinical Subtype ◽  
Post Onset

We investigated the evolution of the neurological and neuropsychological characteristics in a right-handed woman who was 53-years-old at the onset and who showed personality changes and behavioral disorders accompanied by progressive dysarthria. She had hypernasality and a slow rate of speech with distorted consonants and vowels, which progressed as motor disturbances affecting her speech apparatus increased; finally, she became mute two years post onset. Her dysarthria due to bilateral voluntary facio-velo-linguo-pharyngeal paralysis accompanied with automatic-voluntary dissociation fit the description of anterior opercular syndrome. She showed personality changes and behavioral abnormalities from the initial stage of the disease, as is generally observed in frontotemporal degeneration (FTD), and her magnetic resonance image showed progressive atrophy in the frontotemporal lobes; thus, she was clinically diagnosed with FTLD. This patient’s symptoms suggest that FTLD, including bilateral anterior operculum degeneration, causes progressive pseudobulbar paretic dysarthria accompanied by clinical symptoms of FTD, which raises the possibility of a new clinical subtype in the FTLD spectrum.

scholarly journals Specific Features of Designing the Strategy of Company Development at the Initial Stage of its Life Cycle

2018 ◽  
pp. 135-141 ◽  
Author(s):  
A. V. Butov
Keyword(s):  
Business Models ◽  
Subsequent Development ◽  
Corporate Management ◽  
Competitive Advantages ◽  
Initial Stage ◽  
World Markets ◽  
Quality Product ◽  
The World ◽  
Future Potential ◽  
New Perspective

Creation of the new company – a necessary stage of the beginning of any business. This stage is the base of her future potential. In article process of creation of the Starbucks and Nike companies in the absence of significant advantages at the initial stage of their development is investigated, the reasons of success, feature of the subsequent development of effective strategy and competitive advantages as bases of their global expansion in the world markets are considered. Special attention is paid by the author to the embodiment of passionate desire of founders of the companies to creation of a high-quality product of the world level causing in buyers insuperable thirst of possession of Results of a research allow to conclude that creation of the company can begin with elementary actions, including copying of business models of competitors, use of traditional technologies, but means of achievement of leadership in the market nevertheless is the subsequent development of successful strategy and competitive advantages. Studying of experience of creation of the Starbucks and Nike companies allows to simplify process of formation of the new perspective companies and can be used in domestic corporate management.

scholarly journals PRIMARY COMMUNICATIONS OF THE COUNSELLOR WITH THE CUSTOMER IN MANAGEMENT CONSULTATION

2019 ◽  
pp. 158-162
Author(s):  
Yu. D. Krasovskii
Keyword(s):  
Subsequent Development ◽  
Simulation Models ◽  
Top Management ◽  
Management Consulting ◽  
Main Attention ◽  
Digital Format ◽  
Initial Stage ◽  
Management Consultation ◽  
Visual Graphic

Four possible variants of the consultant’s strategies at the initial stage of management consulting of top management of companies at the stage of forming hypotheses and their adjustment in the process of subsequent use of author’s social techniques have been presented in a digital format. A feature of such researches is the subsequent development of simulation models in a digital visual graphic format. The main attention has been paid to the description of research consult-development in the analysis of managerial situations. The most authoritative researchers in the Russian practice of management consulting have been adduced in the list of references.

scholarly journals Establishment of the system of preparation of teaching staff in Buryat-Mongolian ASSR (1920–1930)

2021 ◽  
pp. 27-35
Author(s):  
Viktoriya Vladimirovna Nomogoeva ◽  
Altyna Munkozhargalovna Shoidonova
Keyword(s):  
Cultural Revolution ◽  
Local Population ◽  
Subsequent Development ◽  
Teaching Staff ◽  
Regional Government ◽  
Initial Stage ◽  
History Of ◽  
The Subject ◽  
Professional Teaching ◽  
The Cultural Revolution

The subject of this research is the establishment of the system of preparation of teaching staff in the ethnic republic at the initial stage of the formation of the Soviet state. The relevance of this research is directly related to modernization of educational curriculum at the present time. Thus, numerous educational projects that require the preparation of professional teaching staff are carried out within the framework of the national project “Education”. The authors believe that similar situation developed during the years of the Cultural Revolution. The severe shortage of professional personnel was observed in Buryatia, while the public education was undergoing significant changes. The goal of this article lies in tracing the establishment of the system of preparation of teaching staff in Soviet Buryatia. The analysis of documentary materials of the republican archives allows assessing the results of efforts applied by the republican government to resolve the personnel problem. The scientific novelty consists in the attempt to compare the situation in the 1920s–1930s and 2020s for giving a more in-depth perspective upon the system of preparation of teaching staff. Although this topic is the subject of special research in the scientific literature, it requires further discussion. Methodological framework is comprised of the principles of historicism and systematicity, which view the process in its entirety and in accordance with a particular historical era. The conclusion is made that the results achieved were acceptable within the socioeconomic reality of the region. The regional government was able to create the necessary conditions for preparation of professional teaching staff and lay the groundwork for the subsequent development of the educational system. The creation of the republican system of preparation of teaching staff improved the level of education of the local population and led to the formation of the socialist culture in Soviet Buryatia. The acquired conclusions are valuable for studying regional history of the period of the Cultural Revolution.

scholarly journals Community-Acquired Acute Kidney Injury as a Risk Factor of de novo Heart Failure Hospitalization

2019 ◽  
Vol 9 (4) ◽  
pp. 252-260 ◽  
Author(s):  
Kristen M. Tecson ◽  
Helen Hashemi ◽  
Aasim Afzal ◽  
Timothy A. Gong ◽  
Parag Kale ◽  
...  
Keyword(s):  
Heart Failure ◽  
Primary Care ◽  
Acute Kidney Injury ◽  
Risk Factor ◽  
Serum Creatinine ◽  
Clinical Characteristics ◽  
De Novo ◽  
Kidney Injury ◽  
Subsequent Development ◽  
Prior History

Objectives: Because patients with hospital-acquired acute kidney injury (AKI) are at risk for subsequent development of heart failure (HF) and little is known about the relation between community-acquired AKI (CA-AKI) and HF, we sought to determine if CA-AKI is a risk factor for incident HF hospitalization. Methods: We utilized Baylor Scott &amp; White Health databases at the primary care and inpatient hospitalization levels to identify adults without a prior history of HF who had 2 or more serum creatinine measurements within 13 months in the primary care setting. We defined CA-AKI as a serum creatinine increase ≥0.3 mg/dL or ≥1.5 times the baseline for consecutive values within a 13-month period. We created a flag for de novo HF hospitalization at 90, 180, and 365 days following CA-AKI evaluation. Results: In the analyses, 210,895 unique adults were included, of whom 5,358 (2.5%) had CA-AKI. Those with CA-AKI had higher rates of comorbidities, higher rate of males (48 vs. 42%, p < 0.001), and were older (61.5 [50.3, 73.1] vs. 54.1 [42.8, 64.7] years, p < 0.001) than those who did not have CA-AKI. In total, 607 (0.3%), 833 (0.4%), and 1,089 (0.5%) individuals had an incident HF hospitalization in the 90, 180, and 365 days following the CA-AKI evaluation, respectively. After adjusting for demographic and clinical characteristics, patients with CA-AKI had >2 times the risk of de novo HF hospitalization compared with patients who did not have CA-AKI (90 days: 2.35 [1.83–3.02], p < 0.001; 180 days: 2.52 [2.04–3.13], p < 0.001; 365 days: 2.16 [1.77–2.64], p < 0.001). These multivariable models yielded strong predictive abilities, with the areas under the receiver-operating characteristic curve >0.90. Conclusion: After controlling for baseline and clinical characteristics, patients with CA-AKI were at approximately twofold the risk of de novo HF hospitalization (within 90, 180, and 365 days) compared with those who did not have CA-AKI. Hence, detecting CA-AKI may provide an opportunity for early intervention at the primary care level to possibly delay HF development.

scholarly journals Peculiarities of treatment and rehabilitation of epileptics at the initial stage of disease

1996 ◽  
Vol XXVIII (3-4) ◽  
pp. 14-17
Author(s):  
S. A. Gromov ◽  
V. Е. Mashukova
Keyword(s):  
Test Group ◽  
Young Age ◽  
Clinical Material ◽  
Control Group ◽  
Treatment Efficiency ◽  
Ecg Changes ◽  
Stage Of Disease ◽  
Initial Stage ◽  
High Treatment

On clinical material of 375 patients (200 test group, 75 control group, in 100 cases paroxysmally nonepileptic diseases) peculiarities of treatment and rehabilitation of epileptics at the initial stage of the disease are studied. It is found, that the initial stages of the disease are characterized by: 1) hyperdiagnostics of epilepsy; 2) young age of patients; 3) monomorphism of seizures; 4) absence of ECG-changes; 5) high treatment efficiency; 6) retaining of adaptation to work.

Reaction couples of ceramic thin films prepared by CVD

1988 ◽  
Vol 46 ◽  
pp. 798-799
Author(s):  
D.W. Susnitzky ◽  
S.R. Summerfelt ◽  
C.B. Carter
Keyword(s):  
Thin Film ◽  
Vapor Deposition ◽  
Chemical Vapor ◽  
Deposition Process ◽  
Solid State Reactions ◽  
Spatial Distributions ◽  
Diffusion Couples ◽  
Kinetics Studies ◽  
Ceramic Thin Films ◽  
Initial Stage

Solid-state reactions have traditionally been studied in the form of diffusion couples. This ‘bulk’ approach has been modified, for the specific case of the reaction between NiO and Al2O3, by growing NiAl2O4 (spinel) from electron-transparent Al2O3 TEM foils which had been exposed to NiO vapor at 1415°C. This latter ‘thin-film’ approach has been used to characterize the initial stage of spinel formation and to produce clean phase boundaries since further TEM preparation is not required after the reaction is completed. The present study demonstrates that chemical-vapor deposition (CVD) can be used to deposit NiO particles, with controlled size and spatial distributions, onto Al2O3 TEM specimens. Chemical reactions do not occur during the deposition process, since CVD is a relatively low-temperature technique, and thus the NiO-Al2O3 interface can be characterized. Moreover, a series of annealing treatments can be performed on the same sample which allows both Ni0-NiAl2O4 and NiAl2O4-Al2O3 interfaces to be characterized and which therefore makes this technique amenable to kinetics studies of thin-film reactions.

Micropatterning of Permalloy Films by Electron Lithography

1976 ◽  
Vol 34 ◽  
pp. 448-449
Author(s):  
J. K. Maurin
Keyword(s):  
Electron Beam ◽  
Subsequent Development ◽  
Electron Optical System ◽  
Microelectronic Device ◽  
Magnetic Bubble ◽  
Control Beam ◽  
Photosensitive Material ◽  
Direct Exposure ◽  
Electron Lithography ◽  
Scanning Electron

Conductor, resistor, and dielectric patterns of microelectronic device are usually defined by exposure of a photosensitive material through a mask onto the device with subsequent development of the photoresist and chemical removal of the undesired materials. Standard optical techniques are limited and electron lithography provides several important advantages, including the ability to expose features as small as 1,000 Å, and direct exposure on the wafer with no intermediate mask. This presentation is intended to report how electron lithography was used to define the permalloy patterns which are used to manipulate domains in magnetic bubble memory devices.The electron optical system used in our experiment as shown in Fig. 1 consisted of a high resolution scanning electron microscope, a computer, and a high precision motorized specimen stage. The computer is appropriately interfaced to address the electron beam, control beam exposure, and move the specimen stage.

Decoration technique and surface physics

1978 ◽  
Vol 36 (1) ◽  
pp. 436-437 ◽  
Author(s):  
H. Bethge
Keyword(s):  
Diffusion Path ◽  
Special Importance ◽  
Surface Physics ◽  
Step Structure ◽  
Initial Stage ◽  
Special Cases ◽  
Atomic Surface ◽  
The Mean ◽  
Bulk Structure ◽  
Decoration Technique

Besides the atomic surface structure, diverging in special cases with respect to the bulk structure, the real structure of a surface Is determined by the step structure. Using the decoration technique /1/ it is possible to image step structures having step heights down to a single lattice plane distance electron-microscopically. For a number of problems the knowledge of the monatomic step structures is important, because numerous problems of surface physics are directly connected with processes taking place at these steps, e.g. crystal growth or evaporation, sorption and nucleatlon as initial stage of overgrowth of thin films.To demonstrate the decoration technique by means of evaporation of heavy metals Fig. 1 from our former investigations shows the monatomic step structure of an evaporated NaCI crystal. of special Importance Is the detection of the movement of steps during the growth or evaporation of a crystal. From the velocity of a step fundamental quantities for the molecular processes can be determined, e.g. the mean free diffusion path of molecules.

Nucleation and initial growth of Pd2Si crystals on Si(111)

1993 ◽  
Vol 51 ◽  
pp. 844-845
Author(s):  
Xianghong Tong ◽  
Oliver Pohland ◽  
J. Murray Gibson
Keyword(s):  
High Vacuum ◽  
Dark Field ◽  
Ultra High Vacuum ◽  
Initial Growth ◽  
Surface And Interface ◽  
Dark Field Imaging ◽  
Transmission Electron ◽  
Initial Stage ◽  
Effect Of Surface

The nucleation and initial stage of Pd2Si crystals on Si(111) surface is studied in situ using an Ultra-High Vacuum (UHV) Transmission Electron Microscope (TEM). A modified JEOL 200CX TEM is used for the study. The Si(111) sample is prepared by chemical thinning and is cleaned inside the UHV chamber with base pressure of 1x10−9 τ. A Pd film of 20 Å thick is deposited on to the Si(111) sample in situ using a built-in mini evaporator. This room temperature deposited Pd film is thermally annealed subsequently to form Pd2Si crystals. Surface sensitive dark field imaging is used for the study to reveal the effect of surface and interface steps.The initial growth of the Pd2Si has three stages: nucleation, growth of the nuclei and coalescence of the nuclei. Our experiments shows that the nucleation of the Pd2Si crystal occurs randomly and almost instantaneously on the terraces upon thermal annealing or electron irradiation.

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