Laser therapy as a means of preventing transient bacteremia during dental procedures

1993 ◽  
Vol 74 (4) ◽  
pp. 291-292
Author(s):  
I. A. Latfullin ◽  
S. B. Kovyazina ◽  
A. M. Safiullina ◽  
R. S. Karatai
Keyword(s):  
Blood Vessels ◽  
Laser Therapy ◽  
The State ◽  
Endodontic Treatment ◽  
Periodontal Tissues ◽  
Periodontal Inflammation ◽  
Dental Procedures ◽  
Heart Blood ◽  
Number Of Authors

With dental interventions, bacteremia often develops, which is called transient. Its essence is that after laziness of teeth and dental deposits, curettage, endodontic treatment, a microflora appears in the blood, which is far from indifferent to patients, especially those suffering from diseases of the heart, blood vessels, and kidneys. According to Li I terature, transient bacteremia often occurs during interventions in patients with periodontal inflammation. At the same time, a number of authors believe that the frequency of bacteremia and its severity are influenced not only by the state of the periodontal tissues, but also by the volume of intervention.

scholarly journals Dental status of professional athletes

2020 ◽  
Vol 101 (3) ◽  
pp. 365-370
Author(s):  
J G Hajiyev
Keyword(s):  
Oral Cavity ◽  
Oral Hygiene ◽  
Clinical Manifestations ◽  
Maximum Level ◽  
The State ◽  
Dental Status ◽  
Professional Athletes ◽  
Control Group ◽  
Periodontal Tissues ◽  
Periodontal Inflammation

Aim. To reveal the rate and severity of clinical manifestations of common dental diseases and dentofacial anomalies in professional athletes Methods. The effect of intense physical exertion and overtraining syndrome on the state of the organs and tissues of the dental system were examined in 200 professional athletes aged 1825 years between 2014 and 2016. Five groups where each has the same number of athletes (n=40) included: team sport athletes (volleyball, handball), martial arts athletes (wrestling, boxing), gymnasts, swimmers, athletes. The control group consisted of 40 individuals who were not professionally involved in sports. The state of the oral cavity, in particular periodontal tissues, was judged by changes in the following indicators: prevalence of dentofacial anomalies, the incidence of dental caries, state of the oral cavity hygienic using by simplified oral hygiene index (OHI-S) ( Green J.С., Vermillion J.R., 1963), degree of gums bleeding by using the MuhlemannCowell bleeding index, degrees of severity of periodontopathy by using the papillary-marginal alveolar index (RMA) [Massler, Schour (1949) in Parma modification (1960)]. Results. According to the values of the simplified oral hygiene index the worst state of the oral cavity hygienic was in wrestlers (2.120.022 points) and boxers (2.030.029) compared to the control group (1.620.026, p=0.049 and p=0.001, respectively). Catarrhal gingivitis and generalized chronic periodontitis are most often diagnosed in the groups of wrestling (82.56.01%), gymnastics (77.56.60%), boxing (70.07.25%) and swimming (70.07.25%). Dentoalveolar anomalies were more often detected in boxers (77.5% of cases, p=0.001) and in gymnasts (34.0%, p=0.365) compared to the control group. In these groups, diastema was also more often diagnosed. Conclusion. Periodontal inflammation indicators were higher in wrestlers and gymnasts groups compared to the dental status of all other groups of athletes; caries and maximum level of dental anomalies are more common for boxers.

scholarly journals Evaluation of the Most Stressful Dental Treatment Procedures of Conservative Dentistry among Polish Dental Students

2021 ◽  
Vol 18 (9) ◽  
pp. 4448
Author(s):  
Katarzyna Mocny-Pachońska ◽  
Rafał J. Doniec ◽  
Sylwia Wójcik ◽  
Szymon Sieciński ◽  
Natalia J. Piaseczna ◽  
...  
Keyword(s):  
Dental Treatment ◽  
High Stress ◽  
Dental Students ◽  
Endodontic Treatment ◽  
Stressful Environment ◽  
Caries Treatment ◽  
Dental Procedures ◽  
Conservative Dentistry ◽  
High Level ◽  
Treatment Procedures

Background: Dental schools are considered to be a very stressful environment; the stress levels of dental students are higher than those of the general population. The aim of this study was to assess the level of stress among dental students while performing specific dental procedures. Methods: A survey was conducted among 257 participants. We used an original questionnaire, which consisted of 14 questions assigned to three categories: I—Diagnosis, II—Caries Treatment, and III—Endodontic Treatment. Each participant marked their perceived level of stress during the performed dental treatment procedures. The scale included values of 0–6, where 0 indicates no stress, while 6 indicates high stress. Results: Third- (p=0.006) and fourth-year (p=0.009) women were characterized by a higher level of perceived stress during dental procedures related to caries treatment. Caries treatment procedures were the most stressful for 18.3% of third-year students, 4.3% of fourth-year students, and 3.2% of fifth-year students. Furthermore, 63.4% of third-year students, 47.3% of fourth-year students, and 17.2% of fifth-year students indicated that they felt a high level of stress when performing endodontic procedures. Conclusion: Third- and fourth-year female students are characterized by a higher level of stress during caries and endodontic treatment procedures. The most stressful treatments for participants were endodontic treatment procedures.

Current antibiotic therapy of endo-perio lesions with secondary endodontic involvement

2021 ◽  
Vol 26 (2) ◽  
pp. 105-113
Author(s):  
L. Yu. Orekhova ◽  
V. G. Atrushkevitch ◽  
E. S. Loboda ◽  
V. Yu. Vashneva ◽  
A. A. Petrov
Keyword(s):  
Antibiotic Therapy ◽  
Antibiotic Sensitivity ◽  
Endodontic Treatment ◽  
Comprehensive Treatment ◽  
Sensitivity Testing ◽  
Microbiological Test ◽  
Systemic Antibiotic ◽  
Periodontal Inflammation ◽  
Systemic Antibiotic Therapy ◽  
Group 2

Relevance. Successful treatment of endo-perio lesions depends on the thorough clinical assessment, accurate diagnosis and structural approach to the planning of periodontal and endodontic treatment. Aim – to provide clinical and laboratory evidence about the effectiveness of ciprofloxacin-and-tinidazole-containing antibiotic in the comprehensive treatment of endo-perio lesions with a primary periodontal disease which secondarily affects the pulp.Materials and methods. We examined 29 patients aged from 35 to 50 (mean age 42.3±3.21) with class II endo-perio lesions according to P. Eickholz classification. The patients were randomly divided into 2 groups. All patients had comprehensive periodontal and endodontic treatment with (Group 2) and without (Group 1) antibiotic therapy. The clinical and paraclinical examination included determination of such indices as OHI-s, SL, PMA, SBI, as well as Doppler ultrasound, EPT, CBCT, microbiological test of the discharge from periodontal pockets and root canal system. We selected the systemic antibiotic after the antibiotic sensitivity testing.Results. Comprehensive treatment of endo-perio lesions, which included systemic antibiotic therapy with ciprofloxacin and tinidazole, effectively arrested the inflammation in the periodontium and pulp beginning from the 7th day of use.Conclusion. Cifran ST, a combination broad-spectrum antibiotic, helps reduce periodontal inflammation by effectively eliminating microbiota in the root canals and periodontal pockets in patients with moderate or severe chronic generalized periodontitis. 

Pathogenetic features of periodontitis as complications of orthodontic treatment

2021 ◽  
pp. 64-68
Author(s):  
A. К. Sheregov ◽  
М. S. Mustafayev ◽  
Z. F. Kharaeva
Keyword(s):  
Orthodontic Treatment ◽  
The State ◽  
Complex Treatment ◽  
Periodontal Tissues ◽  
Different Levels

The article presents the results of clinical and microbiological studies and immunological features of the state of periodontal tissues in patients with moderate periodontitis, which developed as a complication of orthodontic treatment. It was found that at the later stages of orthodontic treatment with the development of periodontitis, a complex of persistent changes in the periodontal tissues at different levels of pathogen-esis was revealed in patients. In this connection, in order to plan the complex treatment of patients with periodontitis, which has developed as a complication of orthodontic treatment, and to predict the course of the disease, it is necessary to influence the established and mutually supportive links and indicators of pathogenesis.

scholarly journals Innate Immune Response as a New Challenge in Periodontal Inflammation

2021 ◽  
Author(s):  
Ana Marina Andrei ◽  
Elena Cristina Andrei ◽  
Elena Camelia Stănciulescu ◽  
Mihaela Cezarina Mehedinți ◽  
Mihaela Jana Țuculină ◽  
...  
Keyword(s):  
Immune Response ◽  
Innate Immune Response ◽  
Periodontal Diseases ◽  
Bacterial Species ◽  
Innate Immune ◽  
Beneficial Effects ◽  
Periodontal Tissues ◽  
Periodontal Inflammation ◽  
Genetic And Environmental Factors ◽  
Tlr Signalling

Gingivitis and periodontitis are induced by numerous pathogenic microbiota hosted in the subgingival biofilm that first trigger the innate immune response. Innate immune response is part of a homeostatic system which is the first line defence and defines the host inherited resistance to infection. Both genetic and environmental factors are involved in variable individual susceptibility to inflammation of periodontal tissues. That is why, although more than 600 bacterial species have been detected in the periodontal plaque, the type of bacteria incriminated in the development of the inflammation is still unclear. Moreover, in the last decade gene polymorphisms have been largely recognised as important conditions associated with increased susceptibility to periodontal diseases. Manipulating the immune response by the development of drugs that inhibit adverse host reactions and promote beneficial effects might be of therapeutic or prophylactic importance. This work intends to assess the importance of Toll-like receptors as main effectors of the innate immune response in the triggering, maintenance and progression of periodontal inflammation, as well as of the involvement of synthetic molecules targeting TLR signalling pathways in treating periodontal diseases.

scholarly journals ANALYSIS OF THE EFFECTIVENESS OF IMMUNOTHERAPY USING AN AUTOLOGOUS COMPLEX OF IMMUNOPEPTIDES IN THE SURGICAL TREATMENT OF PERIODONTITIS

2020 ◽  
Vol 17 (35) ◽  
pp. 381-390
Author(s):  
Andrei SEVBITOV ◽  
Alla DAVIDYANTS ◽  
Roman BALYKIN ◽  
Anton TIMOSHIN ◽  
Mariya KUZNETSOVA
Keyword(s):  
Innate Immunity ◽  
Surgical Treatment ◽  
Bone Tissue ◽  
Pathogenic Bacteria ◽  
Alveolar Bone ◽  
The State ◽  
The Body ◽  
Immunological Methods ◽  
Periodontal Tissues ◽  
Antimicrobial Protection

Periodontal disease in the adult population is one of the most pressing problems of dentistry around the world. Thanks to the introduction of modern technologies in practice, it was possible to identify the main mechanisms of the development of this disease at the molecular and genetic level. The interaction of periodontal pathogens with immune factors of antimicrobial protection of the body is the basis of periodontal tissue inflammation and further leads to the destruction of the alveolar bone. Epithelial cells of the gum mucosa play a crucial role against periodontal pathogenic bacteria. Factors of innate immunity play a role not only in antimicrobial protection, but they also support the conditions necessary for the healing and regeneration of periodontal tissues. Therefore, various therapeutic approaches that affect the factors of innate immunity are considered as effective and promising. Clinical examination and determination of factors of innate immunity were performed in 115 patients. Healthy individuals made up a group of 30 people. Patients with chronic generalized periodontitis with varying degrees of severity were 85 people. Each patient underwent orthopantomography on the orthopantomograph Orthophosis XG DS/Ceph (SIRONA Dental System GmbH, Germany) in order to assess the state of the bone tissue of the jaws (the degree of destruction of the cortical layer, the degree of resorption of the interalveolar partitions). Targeted intraoral radiographs were used to assess the state of bone tissue and the quality of surgical treatment. Immunological methods of research were carried out in several stages. The findings of this article make the claim that the use of autologous complex immunopeptides in the surgical treatment of periodontitis reduces the time of achieving a therapeutic effect 2 times, resulting in the rapid relief of the symptoms of inflammation and acceleration of reparative processes.

PRISON TALK: THE MUSLIM BROTHERHOOD'S INTERNAL STRUGGLE DURING GAMAL ABDEL NASSER'S PERSECUTION, 1954 TO 1971

2007 ◽  
Vol 39 (3) ◽  
pp. 433a-433a
Author(s):  
Barbara Zollner
Keyword(s):  
Muslim Brotherhood ◽  
The State ◽  
State System ◽  
Joint Project ◽  
Organizational Reform ◽  
Ideological Discourse ◽  
History Of ◽  
The Muslim Brotherhood ◽  
Internal Struggle ◽  
Number Of Authors

This article investigates the history of the Muslim Brotherhood from 1954 to 1971, when thousands of its members were imprisoned and tortured in Gamel Abdel Nasser's prisons. The period is marked by intervals of crisis, attempts at organizational reform, and ideological discourse, which was prompted by Sayyid Qutb's activist interpretation. However, the Muslim Brotherhood finally developed a moderate ideology, which countered radical Islamist leanings growing within its midst while remaining loyal to Qutb's legacy. This centrist approach to Islamist activism and opposition is epitomized by Duءat la Qudat, which was composed by a number of authors and issued in Hasan al-Hudaybi's name. Written as a joint project of leading Brothers and al-Azhar scholars, the text is evidence of the first steps toward reconciling with the state system during Nasser's presidency.

scholarly journals Inhibition of NF-κB by Pyrrolidine Dithiocarbamate Prevents the Inflammatory Response in a Ligature-Induced Peri-Implantitis Model: A Canine Study

2018 ◽  
Vol 49 (2) ◽  
pp. 610-625 ◽  
Author(s):  
Chun-Yan He ◽  
Li-Peng Jiang ◽  
Cheng-Yue Wang ◽  
Yue Zhang
Keyword(s):  
Inflammatory Response ◽  
Protein Expression ◽  
Quantitative Polymerase Chain Reaction ◽  
Pyrrolidine Dithiocarbamate ◽  
Mrna Levels ◽  
Periodontal Ligament Fibroblasts ◽  
Necrosis Factor Alpha ◽  
Periodontal Tissues ◽  
Periodontal Inflammation ◽  
Tnf Α

Background/Aims: The roles of toll-like receptor 4 (TLR4) and nuclear factor-kappa B (NF-κB) in peri-implantitis are unclear. Here, we used a canine model of peri-implantitis to explore the effects of inhibiting NF-κB with pyrrolidine dithiocarbamate (PDTC) on the inflammatory response in ligature-induced peri-implantitis. Methods: After successfully establishing the peri-implantitis model, beagles were randomly assigned to normal, model or PDTC groups. ELISA tests were used to determine the levels of interleukin (IL)-1, IL-6, IL-8 and tumor necrosis factor alpha (TNF-α). Immunohistochemistry was employed to assess the expression of NF-κB p65. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was performed to determine the mRNA levels of TLR4 and NF-κB p65, and western blot analysis was used to measure the protein levels of TLR4 in periodontal tissues from each group. Periodontal ligament fibroblasts (PDLFs) were cultured and subsequently classified into PDLF normal, PDLF model, PDLF LPS, PDLF PDTC, and PDLF LPS + PDTC groups. An immunofluorescence assay was used to measure the expression level of NF-κB p65. The CCK-8 assay and flow cytometry were performed to evaluate cell proliferation and apoptosis. Results: The in vitro results indicated that NF-κB p65 and TLR4 were upregulated in canine periodontal tissues, and PDTC could suppress the expression levels of NF-κB p65 and TLR4. Inflammation could increase TLR4 protein expression in canine periodontal tissue, and PDTC could inhibit the inflammation-induced increase in TLR4 protein expression. These results revealed that PDTC could reverse the LPS-induced increases in the levels of IL-1, IL-6, IL-8 and TNF-α. In vivo, the results demonstrated that PDTC inhibited the LPS-induced NF-κB p65 upregulation, and PDTC could reverse the inhibitory effect of the PDLF model + LPS on the proliferation of periodontal fibroblasts. The results also showed that in the PDLF model, LPS promoted PDLF apoptosis by inducing implant periodontitis in canines, but PDTC inhibited the PDLF apoptosis and relieved implant periodontitis in canines. Conclusion: Based on our results, we concluded that PDTC can inhibit the expression of NF-κB and alleviate the inflammatory response induced by LPS, thereby preventing periodontal inflammation and reducing the development of peri-implantitis.

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