scholarly journals Dementia in elderly patients as a consequence of arterial hypertension (literature review)

2021 ◽  
Author(s):  
Sergey S Mikhailov ◽  
Kirill L. Kozlov ◽  
Andrey N Shishkevich ◽  
Evgeniy Yu. Bessonov ◽  
Nikolai G. Lukjanov ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
Brain Function ◽  
Middle Age ◽  
The Elderly ◽  
World Population ◽  
Old People ◽  
Aged People ◽  
Number Of Patients ◽  
Elderly And Old People

Alzheimer's disease and vascular dementia are important causes of cognitive decline in the elderly and senile. This problem is becoming increasingly important in connection with the general aging of the world population and an increase in the number of patients with concomitant pathology, among which arterial hypertension plays an important role. There are a number of studies proving the link between arterial hypertension in middle age and dementia in the elderly. It is hoped that the normalization of blood pressure among middle-aged people will reduce the incidence of cognitive dysfunction. It is also known that maintaining blood pressure at acceptable levels in elderly and old people can improve brain function and reduce the prevalence of dementia, but it is not entirely clear which blood pressure numbers are optimal.

Arterial hypertension + past stroke – a case report

2021 ◽  
Vol 14 (3) ◽  
pp. 324-326
Author(s):  
Maria Łukasiewicz ◽  
Marta Swarowska-Skuza
Keyword(s):  
Blood Pressure ◽  
Case Report ◽  
Chronic Disease ◽  
Side Effects ◽  
Arterial Hypertension ◽  
Antihypertensive Therapy ◽  
Systolic Hypertension ◽  
The Elderly ◽  
Isolated Systolic Hypertension ◽  
Special Group

Arterial hypertension, as a very widespread chronic disease, and thus differing in both pathomechanism and course in patients, requires a significant individualization of pharmacotherapy. One such special group is the elderly. Both the low-renin pathomechanism of arterial hypertension and its phenotype (isolated systolic hypertension) imply the choice of a specific pharmacotherapy. Additionally, in this group, side effects should be observed much more vigilantly, while target blood pressure values should be treated more liberally. An example of antihypertensive therapy in a patient belonging to the group described is presented in the following case.

scholarly journals Old hypertensive patient: a hard challenge

2013 ◽  
pp. 109-112
Author(s):  
Giuseppe Rossetti ◽  
Diana Solari ◽  
Maria Laura Rainoldi ◽  
Stefano Carugo
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Elderly People ◽  
Diastolic Pressure ◽  
Beta Blockers ◽  
The Elderly ◽  
Pressure Control ◽  
World Population ◽  
Continuous Increase ◽  
Hypertensive Therapy

BACKGROUND High blood pressure is one of the most important cardiovascular risk factor and its incidence is continuously increasing: on 2025 1/3 of adult world population will suffer of it. Moreover, the therapy of elderly hypertension sufferer patient is still growing up in importance for the continuous increase of world population average life. With ageing, the cardiovascular system suffers neurohormonal and haemodinamic modifications which determine the onset of isolate systolic hypertension, which is characteristic of the elderly. This pathology results linked to a higher cardiovascular risk. AIM OF THE STUDY This review aims to analyze and evaluate present and future therapeutic opportunities about anti-hypertensive therapy in elderly people. DISCUSSION AND CONCLUSIONS Also in elderly people systolic blood pressure values must be lower than 150 mmHg, but it’s also important to maintain diastolic pressure not under 70 mmHg, to avoid phenomenons of cerebral and coronary hypo-perfusion (J curve). The benefits of an effective anti-hypertensive therapy are achieved thanks to both blood pressure lowering “per se” and to the decrease of cardiovascular mortality and morbility. Blood pressure control in the elderly is a hard challenge for the low compliance to the therapy, for the importance of the comorbidity and for the supplementary risk factors. ESH-ESC 2007 guidelines recommend for elderly highblood pressure sufferer patient the use first of all of calcium-antagonists and thiazides diuretics, and for second line ACE-inhibitors, ARB and beta-blockers. In several patients combinations of two or more drugs are necessary to obtain pressure control.

REPRESENTATION OF SOCIAL WORKERS WITH VARIOUS PROFESSIONAL EXPERIENCE ABOUT EMOTIONAL FEATURES OF ELDERLY AND OLD PEOPLE

2021 ◽  
pp. 893-899
Author(s):  
В. В. Лемиш
Keyword(s):  
Social Workers ◽  
Effective Interaction ◽  
Elderly Person ◽  
The Elderly ◽  
Professional Experience ◽  
Repertory Grid Technique ◽  
Old People ◽  
Grid Technique ◽  
Service Departments ◽  
Elderly And Old People

В статье представления об эмоциональных особенностях пожилого и старого человека рассматриваются как одно из условий эффективного взаимодействия социальных работников со своими клиентами. В качестве респондентов выступили социальные работники с различным профессиональным стажем, работающие в отделениях обслуживания граждан пожилого возраста и инвалидов. Содержание представлений исследовали с помощью авторской психосемантической методики, разработанной на основе применения метода репертуарных решеток Келли ( n =534). Показано, что профессиональный стаж в целом мало влияет на восприятие эмоциональных особенностей клиентов: характеристики пожилого человека оценены невысоко, в образе старого человека доминируют негативные оценки. Исключение составляют социальные работники со стажем 20 лет и более, чьи оценки как пожилого, так и старого человека сближаются с оценками взрослого. Representation of the emotional characteristics of elderly and old person is considered in the article as one of the conditions for the effective interaction of social workers with their clients. The respondents were social workers with various professional backgrounds, who works in the service departments of elderly citizens and people with disabilities. The content of the representations was investigated by using the author’s psychosemantic technique, which was developed on the basis of the Kelly’s Repertory Grid Technique ( n =534). It is shown that professional experience has little effect on the perception of the emotional characteristics of clients in general: the characteristics of an elderly person are not highly rated, negative assessments dominate in the image of an old person. The exception is social workers with experience of 20 years or more, whose estimates of both the elderly and the old person are close to the estimate of an adult.

scholarly journals Hemodynamic evaluation of elderly patients during laparoscopic cholecystectomy

2018 ◽  
Vol 45 (2) ◽  
Author(s):  
LUIZ PAULO JACOMELLI RAMOS ◽  
RODRIGO BARCELLOS ARAÚJO ◽  
MARIA DO CARMO VALENTE CASTRO ◽  
MARIA ROBERTA MENEGUETTI SERAVALLI RAMOS ◽  
JOSÉ ANTONIO CUNHA-E-SILVA ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Laparoscopic Cholecystectomy ◽  
Ejection Fraction ◽  
Elderly Patients ◽  
The Elderly ◽  
Statistical Correlation ◽  
Hemodynamic Changes ◽  
Number Of Patients ◽  
Elective Laparoscopic Cholecystectomy ◽  
The Mean

ABSTRACT Objective: to demonstrate hemodynamic changes during laparoscopic cholecystectomy in elderly patients with trans-esophageal echocardiography. Methods: we studied 31 elderly patients (aged 60 years or older), ASA I or II, who underwent elective laparoscopic cholecystectomy under general, standardized anesthesia, with cardiovascular parameters measured using transesophageal echocardiography at three different times: before the pneumoperitoneum (T1), after CO2 insufflation (T2) and at deflation (T3). We statistically evaluated changes in systolic, diastolic and mean blood pressure, heart rate, cardiac output and index, and ejection fraction. Results: although small, only the diastolic blood pressure (DBP) and ejection fraction (EF) variations were statistically significant. The mean ± standard deviation of DBP in mmHg at the different times were: T1=67.5±10.3; T2=73.6±12.4; and T3=66.7±9.8. And for EF, in percentage (%) they were: T1=66.7±10.4; T2=63.2±9.9; and T3=68.1±8.4. There was no statistical correlation between hemodynamic variations, age and number of patients’ comorbidities. Conclusion: laparoscopic cholecystectomy causes few hemodynamic changes that are well tolerated by the majority of the elderly patients; prior impairment of ventricular function represents a threat in elderly patients during surgery; there appears to be a lower hemodynamic effect caused by the pneumoperitoneum than by the patient’s positioning in a reverse Trendelemburg during surgery.

scholarly journals Efficacy and tolerance of Arifam in patients with arterial hypertension over 55 years old: main results of the observational program ARBALET

2018 ◽  
pp. 64-74
Author(s):  
Zh. D. Kobalava ◽  
V. V. Tolkacheva ◽  
N. Kh. Bagmanova ◽  
E. R. Khasanova
Keyword(s):  
Blood Pressure ◽  
Adverse Events ◽  
Arterial Hypertension ◽  
Positive Response ◽  
Fixed Combination ◽  
Blood Pressure Measurement ◽  
High Efficacy ◽  
Ambulatory Blood Pressure Measurement ◽  
Number Of Patients ◽  
Observational Program

Aim.To assess the effectiveness and safety of therapy with fixed combination of amlodipine/indapamide (Arifam) in outpatients with arterial hypertension (AH) over 55 years old.Material and methods.We included 2217 patients in the observation — 692 (31%) men and 1521 (69%) women. Changes in the course of 3-month therapy of systolic and diastolic blood pressure (BP), the frequency of achievement of target BP levels (<140/90 mm Hg), responder rate during the clinical and ambulatory blood pressure measurement were evaluated and.Results.With the use of Arifam fixed combination 89,81% of patients achieved target BP level by the 3rd month of treatment, 73,77% of patients achieved positive response in 2 weeks, 94,88% of patients — after 1 month. According to the selfcontrol data, the target BP level (<135/85 mm Hg) was achieved in 79,47% of patients. The number of patients with pulse BP <60 mm Hg increased after 3 months of treatment to 81,97%. Also 48 (2,17%) patients discontinued participation; 6 (0,28%) patients — due to the development of adverse events.Conclusion.The ARBALET program has demonstrated high efficacy and tolerance of using Arifam fixed combination in outpatients over 55 years old with hypertension.

scholarly journals Efetividade de programa de apoio a terceira idade no controle da hipertensão arterial

2019 ◽  
Vol 9 (28) ◽  
pp. 26-36
Author(s):  
Eduardo Expedito Valeriano Batista ◽  
Bruno Almeida Rezende
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Elderly Patients ◽  
Arterial Hypertension ◽  
Blood Pressure Measurement ◽  
The Elderly ◽  
Relevant Information ◽  
Support Program ◽  
Cross Sectional ◽  
Systemic Arterial Hypertension

Estudar o perfil do idoso portador de Hipertensão Arterial Sistêmica (HAS) inserido em um Grupo de Apoio a Terceira Idade (GATI), sua adesão ao tratamento medicamentoso e o controle dos níveis pressóricos. Estudo transversal, descritivo e comparativo em 72 idosos portadores de HAS divididos em dois grupos: participantes e não participantes de um GATI na cidade de Jequeri (MG). Os dados foram coletados por entrevistas através do questionário de adesão a medicamentos auto referido, aferição da pressão arterial e coleta de dados do prontuário. A maioria dos indivíduos era do sexo feminino, casados e praticavam atividades físicas regulares. Os participantes do GATI apresentaram maior escolaridade, maior adesão ao tratamento medicamentoso da HAS, maior proporção de praticantes de atividades físicas, menor IMC e menor proporção de fumantes e melhores índices pressóricos. A implementação de GATI pode auxiliar no controle dos níveis pressóricos em pacientes portadores de HAS.Descritores: Hipertensão Arterial Sistêmica, Idoso, Envelhecimento. Effectiveness of a support program for the elderly in the control of Systemic Arterial HypertensionAbstract: To study the profile of elderly patients with Systemic Arterial Hypertension (SAH) included in a support program for elderly people (SPEP) at Jequeri city (MG), as well as their drug treatment adherence and control of blood pressure levels. Cross-sectional, descriptive and comparative study performed in 72 elderly patients with SAH divided into two groups: participants and non-participants of a SPEP. The data were collected by interviews through a self-reported adherence questionnaire, blood pressure measurement, as well as the collection of relevant information to the patient’s medical record. Most of the individuals were female, married, and engaged in regular physical activity. SPEP participants presented higher schooling, greater adherence to the medical treatment of hypertension, greater proportion of physical activity practitioners, lower BMI, a lower proportion of smokers and better blood pressure indexes. The implementation of SPEP can help control pressure levels in patients with SAH.Descriptors: Systemic Arterial Hypertension, Elderly, Senior group, Aging. Efectividad de programa de apoyo a la tercera edad en el control de la hipertensión arterialResumen: Estudar o perfil do idoso portador de Hipertensão Arterial Sistémica (HAS) inserido em um Grupo de Apoio a Terceira Idade (GATI), sua adesão ao tratamento medicamentoso e o controle dos níveis pressóricos. Estudo transversal, descritivo e comparativo em 72 idosos portadores de HAS divididos em dois grupos: participantes e não participantes de um GATI na cidade de Jequeri (MG). Os dados foram coletados por entrevistas através do questionário de adesão a medicamentos auto referido, aferição da pressão arterial e coleta de dados do prontuário. A maioria dos indivíduos era do sexo feminino, casados e praticavam atividades físicas regulares. Os participantes do GATI apresentaram maior escolaridade, maior adesão ao tratamento medicamentoso da HAS, maior proporção de praticantes de atividades físicas, menor IMC e menor proporção de fumantes e melhores índices pressóricos. A implementação de GATI podem auxiliar no controle dos níveis pressóricos em pacientes portadores de HAS.Descriptores: Hipertensão Arterial Sistêmica, Idoso, Envelhecimento.

The role of inflammation in the development of post-stroke depression in elderly patients

2022 ◽  
pp. 841-847
Author(s):  
О.А. Осипова ◽  
Н.И. Клюшников ◽  
Е.В. Гостева ◽  
О.Н. Белоусова ◽  
Н.И. Жернакова ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Elderly Patients ◽  
Middle Age ◽  
The Elderly ◽  
Middle Aged ◽  
Post Stroke ◽  
Aged People ◽  
Tnf Α ◽  
Post Stroke Depression

Цель исследования - изучение роли цитокинов, соотношения нейтрофилов и лимфоцитов в развитии постинсультной депрессии (ПД) у больных пожилого возраста. В исследование были включены 110 больных с острым ишемическим инсультом, из них 60 человек среднего возраста (52±5 лет) и 50 - пожилого возраста (66±4 года). Контрольную группу составили 20 человек среднего возраста без инсульта в анамнезе. Через 3 мес наблюдения ПД в пожилом возрасте развилась у 28 (56 %) больных, в среднем возрасте - у 26 (43,3 %). Больные пожилого возраста с ишемическим инсультом, у которых развилась ПД, были достоверно старше (7,9 %, р<0,05), чаще имели артериальную гипертензию (12,4 %, р<0,05), уровень гликемии выше на 16,1 % (р<0,05), триглицеридов - на 14 % (р<0,05), ЛПНП - на 12,8 % (р<0,05). Больные среднего возраста с ПД имели ИМТ выше на 8,1 % (р<0,05), уровень гликемии - на 9,6 % (р<0,05), триглицеридов - на 10,9 % (р<0,05), ЛПНП - на 9,7 % (р<0,05), чем больные без депрессии. Пожилые больные с ишемическим инсультом и ПД имели более высокий уровень цитокинов - IL-1β был выше на 35,4 % (р<0,01), TNF-α - на 27 % (р<0,01), INF-γ - на 18 % (р<0,01), чем у больных без ПД. У больных пожилого возраста с ПД соотношение нейтрофилов и лимфоцитов (Н/Л) было на 46 % (p<0,001) выше, чем у больных без ПД. В группе больных пожилого возраста при наличии ПД соотношение Н/Л было на 50 % (p<0,001) выше, чем в аналогичной группе среднего возраста. Таким образом, у пожилых больных с ишемическим инсультом уровень маркеров воспаления может иметь прогностическое значение в развитии постинсультной депрессии. The aim of the study was to study the role of cytokines, the ratio of neutrophils and lymphocytes in the development of post-stroke depression in elderly patients. The study included 110 patients with acute ischemic stroke, including 60 middle-aged people (52±5 years) and 50 elderly people (66±4 years). The control group consisted of 20 middle-aged people without a history of stroke. After 3 months of follow-up, post-stroke depression (PSD) developed in the elderly in 28 patients (56 %), in the middle age in 26 patients (43,3 %). Patients with ischemic stroke in the elderly who developed PSD were significantly older (7,9 %, p<0,05), more often had arterial hypertension (12,4 %, p<0,05), the level of glucose was 16,1 % higher (p<0,05), triglycerides by 14 % (p<0,05), LDL-C by 12,8 % (p<0,05). In middle age, patients with post-stroke depression had a body mass index higher by 8,1 % (p<0,05), a glucose level by 9,6 % (p<0,05), triglycerides by 10,9 % (p<0,05), LDL-C by 9,7 % (p<0,05) than patients without PSD. Elderly patients with ischemic stroke and PSD had higher levels of cytokines - IL-1β was 35,4 % higher (p<0,01), TNF-α by 27 % (p<0,01), INF-γ by 18 % (p<0,01) than in patients without PSD. In elderly patients with PSD, the ratio of neutrophils and lymphocytes (N/L) is 46 % (p<0,001) higher than in patients without PSD. In the elderly, in the presence of PSD, the N/L ratio was 50 % (p<0,001) higher than in the same middle-aged group. Thus, in elderly patients with ischemic stroke, the level of inflammatory markers may have a prognostic value in the development of post-stroke depression.

P6366High blood pressure cut-off by 130/80 mmHg in middle-ages may be valid for predicting heart failure in ages of seventies

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
N Sasaki ◽  
R Ozono ◽  
R Maeda ◽  
Y Kihara
Keyword(s):  
Heart Failure ◽  
Blood Pressure ◽  
Middle Ages ◽  
High Blood Pressure ◽  
Cardiac Disease ◽  
Middle Age ◽  
The Elderly ◽  
Pressure Measurements ◽  
Elderly Age ◽  
Antihypertensive Medications

Abstract Background ESC/ESH Guidelines (2018) recommended that treated BP values should be targeted to 130/80 mmHg or lower in most patients. However, it remains unclear whether this target in middle-aged population is associated with future development of heart failure. Purpose We conducted a retrospective analysis to determine whether high blood pressure cut-off by 130/80 mmHg in the middle-age predicts the risk of heart failure, detected by high N-terminal pro-brain natriuretic peptide (NT-proBNP) level, in the elderly in a cohort in which longitudinal blood pressure records exist. Methods The cohort consists of health check examinee who consulted the examination institute between 2015 and 2018 (n=8513), aged 70 years or older, and had previous institution-visit record at least once from 50 to 69 years old. We measured serum NT-proBNP level in the all examinee and defined the group of high NT-proBNP as ≥144 pg/ml [defined as the highest quartile, n=2135 (25%)]. The number of participants whose previous blood pressure records exists was 8123 (95%) for 65–69 years old, 6980 (82%) for 60–64 years old, 5233 (61%) for 55–59 years old, and 3018 (35%) for 50–54 years old, respectively. The each generation subgroups were divided into the three gradual categories according to the blood pressure records: SBP ≥140 and/or DBP ≥90, SBP130–139 and/or DBP80–89, and SBP <130 and DBP <80 mmHg. Results Categorization to high NT-proBNP group in ages of 70 or more was significantly associated with the categorization to high blood pressure, which was not only the SBP ≥140 and/or DBP ≥90 mmHg but also the SBP130–139 and/or DBP80–89 mmHg at any time points of previous blood pressure measurements. The multivariable adjusted odds ratios for having high NT-proBNP level in the elderly against the two high blood pressure categories based on the previous blood pressure measurements were shown in the Table. Table 1. Multivariable adjusted OR for high NT-proBNP level in elderly Age N SBP 130–139 and/or DBP 80–89 SBP ≥140 and/or DBP ≥90 OR P OR P 65–69 8123 1.30 <0.001 1.68 <0.001 60–64 6980 1.26 0.002 1.55 <0.001 55–59 5233 1.25 0.013 1.41 <0.001 50–54 3018 1.32 0.023 1.58 <0.001 Model included age, gender, BMI, serum creatinine, hemoglobin, and presence of antihypertensive medications, and cardiac disease. Conclusion High blood pressure cut-off by 130/80 mmHg in the middle-age may be valid to predict the risk of heart failure in the elderly.

scholarly journals Arterial hypertension: which targets in over-75-year people?

2016 ◽  
Vol 84 (1-2) ◽  
Author(s):  
Gian Francesco Mureddu
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
Cardiovascular Prevention ◽  
The Elderly ◽  
Blood Pressure Target ◽  
General Health Status ◽  
J Curve ◽  
Pressure Lowering ◽  
Better Than ◽  
Intensive Blood Pressure

<p>Arterial hypertension has always been considered the main risk factor in cardiovascular prevention. However, the goals of anti-hypertensive treatment (targets) in the elderly has long been under discussion. The results of the studies in favor of the hypothesis "the lower the better" than those that argue against the existence of the phenomenon of the J-curve, that is, the hypothesis according to which mortality increases to too low pressure values  lower than 115/75 mmHg, are still controversial. However, in elderly patients the association between blood pressure lowering and increased cardiovascular events seems to depend on the general health status, that means the presence of comorbidity, frailty and / or disability. Recent data from the SPRINT study show that the benefit of an intensive blood pressure target (SBP &lt;120 mmHg) compared to a usual target (SBP &lt;140 mmHg), appears to be greater in the oldest hypertensive patients (≥75 years). The cardio-geriatric functional assessment can provide useful information to better stratify the elderly and to define more accurately the pressure targets, the choice is individual.</p><p><strong>Riassunto</strong></p><p>L’ipertensione arteriosa è da sempre  considerata il fattore di rischio centrale in prevenzione cardiovascolare. Tuttavia gli obbiettivi del trattamento anti-ipertensivo (target pressori) nei soggetti anziani è  da molti anni oggetto di discussione. Il risultati degli studi a favore dell’ipotesi “the lower the better” rispetto a quelli contrari che sostengono l’esistenza del  fenomeno della cosiddetta curva J, l’ipotesi cioè secondo la quale la mortalità aumenta per valori di pressione troppo bassi, inferiori a 115/75 mmHg, sono tutt’ora controversi. Tuttavia in pazienti anziani l’associazione tra riduzione dei valori di pressione arteriosa e aumento degli eventi cardiovascolari  sembra dipendere dallo stato di salute generale, ovvero alla presenza di comorbidità, fragilità e/o disabilità. I recenti dati dello studio SPRINT. Mostrano che il beneficio di un target pressorio intensivo  (PAS&lt;120 mmHg) rispetto ad un target usuale  (PAS&lt;140 mmHg), sembra essere maggiore nei soggetti  ipertesi più anziani (≥75 anni). La valutazione funzionale cardio-geriatrica può fornire informazioni utili a stratificare meglio  i soggetti anziani e a definirne in maniera più accurata i target pressori, la cui scelta rimane individuale.  </p>

P6370Epidemiology of arterial hypertension in one of the regions of Russia

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
E A Smirnova ◽  
S S Yakushin ◽  
Y V Terekhovskaya ◽  
A N Vorobyev
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Arterial Hypertension ◽  
Representative Sample ◽  
Antihypertensive Drugs ◽  
Men And Women ◽  
The Past ◽  
Number Of Patients ◽  
Increased Risk

Abstract Aim To study the dynamics of the prevalence, awareness, risk factors (RF) and treatment of arterial hypertension (AH) among men and women according to a survey of a representative sample of the population of the Ryazan region (RR) in 2007–2016. Materials and methods In 2002, as a part of the Russian epidemiological “EPOCH” study, a representative sample of the RR population (2098 people, average age 44.8±18.6 years) was formed and surveyed using step-by-step randomization of medical institutions, medical districts and apartments. A repeated survey of the sample was conducted in 2007 (1,760 people, response 83.9%) and in 2016 (1,497 people, response 85.1%). The AH group included persons with blood pressure ≥140/90 mmHg detected during the double measurement and with normal blood pressure while receiving antihypertensive therapy. In individuals with AH the risk factors were assessed: smoking, alcohol abuse, salt abuse, obesity, burdened family history, low physical activity. Results The prevalence of AH over the past 9 years has increased from 39.3% to 43.9%, p<0.001. The age-standardized prevalence of AH among women is higher than among men as in 2007 (42.1% versus 34.8%, p<0.001) and in 2016 (46.9% vs. 41.8%, p<0.05). Women's awareness about having AH increased from 83.9% to 88.9%, p<0.05, in men it decreased (84.0% against 77.4% in 2007, p>0.05). In the group of persons with AH, the more common risk factors are older age (56.8%), hereditary predisposition (58.9%), low physical activity (96.0%) and obesity (34.3%) compared with persons without AH (12.9%, 48.2%, 84.5% and 9.2%, respectively), they smoke less often (10.7% versus 23.2%) and use extra salt less often (29.5% against 38.4%), p<0.001. The number of patients taking antihypertensive drugs reached 91.2% against 84.0% in 2007, p<0.001. There was a decrease in the number of AH patients who: are treated intermittently (from 12.3% to 3.6%, p<0.001), who take drugs only when blood pressure is high (from 16.2% to 6.2%, p<0.001). The most frequently used antihypertensive drugs are still ACE inhibitors (64.8%), beta-blockers (48.9%), diuretics (42.5%), ARBs (29.2%) and calcium channel blockers (21.3%). The ratio of effectively treated AH patients increased in men from 14.6% to 27.8%, p<0.001, in women from 25.0% to 39.5%, p<0.001. A negative influence on the effectiveness of therapy was caused by smoking (RR 1.23; CI 1.11–1.37, p=0.005), salt abuse (RR 1.11; CI 1.06–1.23, p=0.04) and obesity (RR 1.16; CI 1.06–1.27, p=0.003). Conclusion Over the past nine years, the prevalence of hypertension in both the men and women has significantly increased in the Ryazan region. Increased treatment coverage and positive changes in drug therapy led to an increase in the number of effectively treated patients (from 21.4% to 35.5%, p<0.001). Obesity, smoking, salt abuse are associated with an increased risk of non-effectiveness of hypertension therapy.

Sign in / Sign up

Export Citation Format

Share Document