Evaluation of the Impact of Stagnation Temperatures in Different Prototypes of Low Concentration PVT Solar Panels

2016 ◽  
Author(s):  
S. Bastos ◽  
João Gomes ◽  
Mafalda Henriques ◽  
Linkesh Diwan ◽  
Olle Olsson
Keyword(s):  
Solar Panels ◽  
Low Concentration ◽  
The Impact

scholarly journals Suppression of influenza A virus replication in human lung epithelial cells by noncytotoxic concentrations bafilomycin A1

2015 ◽  
Vol 308 (3) ◽  
pp. L270-L286 ◽  
Author(s):  
Behzad Yeganeh ◽  
Saeid Ghavami ◽  
Andrea L. Kroeker ◽  
Thomas H. Mahood ◽  
Gerald L. Stelmack ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Host Cell ◽  
Influenza A Virus ◽  
Influenza A ◽  
Life Cycles ◽  
Host Cells ◽  
Nuclear Accumulation ◽  
Low Concentration ◽  
High Concentrations ◽  
The Impact

Subcellular trafficking within host cells plays a critical role in viral life cycles, including influenza A virus (IAV). Thus targeting relevant subcellular compartments holds promise for effective intervention to control the impact of influenza infection. Bafilomycin A1(Baf-A1), when used at relative high concentrations (≥10 nM), inhibits vacuolar ATPase (V-ATPase) and reduces endosome acidification and lysosome number, thus inhibiting IAV replication but promoting host cell cytotoxicity. We tested the hypothesis that much lower doses of Baf-A1also have anti-IAV activity, but without toxic effects. Thus we assessed the antiviral activity of Baf-A1at different concentrations (0.1–100 nM) in human alveolar epithelial cells (A549) infected with IAV strain A/PR/8/34 virus (H1N1). Infected and mock-infected cells pre- and cotreated with Baf-A1were harvested 0–24 h postinfection and analyzed by immunoblotting, immunofluorescence, and confocal and electron microscopy. We found that Baf-A1had disparate concentration-dependent effects on subcellular organelles and suppressed affected IAV replication. At concentrations ≥10 nM Baf-A1inhibited acid lysosome formation, which resulted in greatly reduced IAV replication and release. Notably, at a very low concentration of 0.1 nM that is insufficient to reduce lysosome number, Baf-A1retained the capacity to significantly impair IAV nuclear accumulation as well as IAV replication and release. In contrast to the effects of high concentrations of Baf-A1, very low concentrations did not exhibit cytotoxic effects or induce apoptotic cell death, based on morphological and FACS analyses. In conclusion, our results reveal that low-concentration Baf-A1is an effective inhibitor of IAV replication, without impacting host cell viability.

scholarly journals Impact of Solar Panel Orientation on the Integration of Solar Energy in Low-Voltage Distribution Grids

2020 ◽  
Vol 2020 ◽  
pp. 1-13 ◽  
Author(s):  
Joannes I. Laveyne ◽  
Dimitar Bozalakov ◽  
Greet Van Eetvelde ◽  
Lieven Vandevelde
Keyword(s):  
Low Voltage ◽  
Real Life ◽  
Solar Panel ◽  
Solar Panels ◽  
Voltage Distribution ◽  
Distribution Grid ◽  
Voltage Balance ◽  
Residential Distribution ◽  
The Impact ◽  
Distribution Grids

In Belgium, and many other countries, rooftop solar panels are becoming a ubiquitous form of decentralised energy production. The increasing share of these distributed installations however imposes many challenges on the operators of the low-voltage distribution grid. They must keep the voltage levels and voltage balance on their grids in check and are often regulatory required to provide sufficient reception capacity for new power producing installations. By placing solar panels in different inclinations and azimuth angles, power production profiles can possibly be shifted to align more with residential power consumption profiles. In this article, it is investigated if the orientation of solar panels can have a mitigating impact on the integration problems on residential low voltage distribution grids. An improved simulation model of a solar panel installation is constructed, which is used to simulate the impact on a residential distribution grid. To stay as close to real-life conditions as possible, real irradiation data and a model of an existing grid are used. Both the developed model as the results on grid impact are evaluated.

scholarly journals The Synergistic Effect of an ATP-Competitive Inhibitor of mTOR and Metformin on Pancreatic Tumor Growth

2020 ◽  
Vol 4 (9) ◽  
Author(s):  
Ghada A Soliman ◽  
Surendra K Shukla ◽  
Asserewou Etekpo ◽  
Venugopal Gunda ◽  
Sharalyn M Steenson ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Pancreatic Tumor ◽  
Single Agent ◽  
Nutrient Sensing ◽  
Pancreatic Tumors ◽  
Mice Model ◽  
High Concentration ◽  
Orthotopic Mouse Model ◽  
Low Concentration ◽  
The Impact

ABSTRACT Background The mechanistic target of rapamycin complex 1 (mTORC1) is a nutrient-sensing pathway and a key regulator of amino acid and glucose metabolism. Dysregulation of the mTOR pathways is implicated in the pathogenesis of metabolic syndrome, obesity, type 2 diabetes, and pancreatic cancer. Objectives We investigated the impact of inhibition of mTORC1/mTORC2 and synergism with metformin on pancreatic tumor growth and metabolomics. Methods Cell lines derived from pancreatic tumors of the KPC (KrasG12D/+; p53R172H/+; Pdx1-Cre) transgenic mice model were implanted into the pancreas of C57BL/6 albino mice (n = 10/group). Two weeks later, the mice were injected intraperitoneally with daily doses of 1) Torin 2 (mTORC1/mTORC2 inhibitor) at a high concentration (TH), 2) Torin 2 at a low concentration (TL), 3) metformin at a low concentration (ML), 4) a combination of Torin 2 and metformin at low concentrations (TLML), or 5) DMSO vehicle (control) for 12 d. Tissues and blood samples were collected for targeted xenometabolomics analysis, drug concentration, and cell signaling. Results Metabolomic analysis of the control and treated plasma samples showed differential metabolite profiles. Phenylalanine was significantly elevated in the TLML group compared with the control (+426%, P = 0.0004), whereas uracil was significantly lower (–38%, P = 0.009). The combination treatment reduced tumor growth in the orthotopic mouse model. TLML significantly decreased pancreatic tumor volume (498 ± 104 mm3; 37%; P < 0.0004) compared with control (1326 ± 134 mm3; 100%), ML (853 ± 67 mm3; 64%), TL (745 ± 167 mm3; 54%), and TH (665 ± 182 mm3; 50%) (ANOVA and post hoc tests). TLML significantly decreased tumor weights (0.66 ± 0.08 g; 52%) compared with the control (1.28 ± 0.19 g; 100%) (P < 0.002). Conclusions The combination of mTOR dual inhibition by Torin 2 and metformin is associated with an altered metabolomic profile and a significant reduction in pancreatic tumor burden compared with single-agent therapy, and it is better tolerated.

scholarly journals Analysis of influence of climatic factors on selecting types of solar panels

2020 ◽  
Vol 2020 (2) ◽  
pp. 21-26
Author(s):  
Sergey Vladimirovich Golovko ◽  
Dmitry Anatolyevich Zadorkin
Keyword(s):  
Solar Cell ◽  
Solar Radiation ◽  
Cell Surface ◽  
Alternative Energy ◽  
Climatic Factors ◽  
Climatic Conditions ◽  
Solar Panels ◽  
Efficient Operation ◽  
The Impact ◽  
Solar Rays

The article outlines the problem of the influence of climatic factors on the efficiency of solar panels operation. Not long ago the idea of free electricity seemed incredible. However, the development of technologies rapidly progresses, and the alternative energy captures more and more supporters every day. The popularity of solar panels is growing quite rapidly, since photovoltaic converters are an efficient source of electricity. But for more efficient operation of solar cells it is necessary to create the specific conditions, taking into account the location of the unit. There have been considered the factors of more efficient operation of the photovoltaic converters: the hash climatic conditions and the intensity of solar radiation depending on the angle of reducing the impact of the solar rays onto the solar cell surface.

scholarly journals Analyzing the Impact of Agrophotovoltaic Power Plants on the Amenity Value of Agricultural Landscape: The Case of the Republic of Korea

2021 ◽  
Vol 13 (20) ◽  
pp. 11325
Author(s):  
Tae-Hwa Kim ◽  
Ki-Suk Chun ◽  
Seung-Ryong Yang
Keyword(s):  
Power Plants ◽  
Public Perception ◽  
Agricultural Landscape ◽  
Solar Panels ◽  
Amenity Value ◽  
The Public ◽  
Benefit Function ◽  
The Republic ◽  
The Impact ◽  
Detrimental Impact

Recently, in Korea, there have been some disturbing events forcing a trade-off between the expansion of agrophotovoltaic (APV) power plants and the agricultural policy to enhance the public benefit function of agriculture. Under this context, this study attempts to examine the public perception of agricultural landscape and the APV power plants and to analyze the impact of APV power plants on the amenity value of the agricultural landscape. The results of the analysis based on the choice experiment method shows that the marginal willingness-to-pay for a rural tourism accommodation with a ‘agricultural landscape view’ is USD 64.37 higher compared to ‘agrophotovoltaics panel view.’ This implies that the value of the agricultural landscape decreases when solar panels are installed on farmland, signifying the detrimental impact of the APV power plants on the multi-functionality of agriculture. If the installation of APVs is expanded to farmlands nationwide, the amenity value of agricultural landscape is estimated to decrease by USD 1.70 billion or 55.0% of the total estimated amenity value in Korea.

scholarly journals Synthesis of Reusable Cyclodextrin Polymers for Removal of Naphthol and Naphthylamine from Water

2021 ◽  
Author(s):  
Weifeng Xu ◽  
Xiang Liu ◽  
Jianzhe Cai ◽  
Tiemeng Xue ◽  
Kewen Tang
Keyword(s):  
Adsorption Equilibrium ◽  
Order Kinetic ◽  
Naphthalene Derivatives ◽  
Initial Concentration ◽  
Low Concentration ◽  
Adsorption Temperature ◽  
Order Kinetic Model ◽  
Pseudo Second Order ◽  
Cyclodextrin Polymers ◽  
The Impact

Abstract As one group of important naphthalene derivatives, naphthol and naphthylamine, are diffusely employed as dye intermediates. The presence of naphthol and naphthylamine in water systems may pose risks to the environment and public health due to their carcinogenicity. In this study, four mesoporous polymers prepared by β-cyclodextrin derivatives and tetrafluoroterephthalonitrile were obtained, and applied to deal with 1-naphthylamine, 2-naphthylamine, 1-naphthol, and 2-naphthol from water. The impact of adsorption time, initial concentration of naphthol and naphthylamine, and temperature on the adsorption efficiency of the four polymers were explored separately. The four polymers present fast adsorption kinetics towards naphthol and naphthylamine, attaining 93%~100% of adsorption equilibrium uptake for 1-naphthol, 1-naphthylamine, 2-naphthylamine in 15 min, and 87%~90% of equilibrium uptake for 2-naphthol in 15 min. The kinetics could be depicted well by the pseudo-second-order kinetic model. The adsorption isotherms of the four polymers towards naphthol and naphthylamine accord with Redlich-Peterson or Sips model. The adsorption ratio increases fast with reducing the initial concentration of naphthol and naphthylamine, which suggest that these polymers are applicable to removing low concentration of naphthol and naphthylamine from water. The adsorption ratio of naphthol and naphthylamine in 5 mg/L, can achieve over 95% in 25 oC. In addition, the four polymers can be effortlessly recovered by a gentle and simple washing procedure with little reduction in performance. The adsorption performance of the four polymers towards the four naphthalene derivatives can be improved by increasing the adsorption temperature. In conclusion, the prepared β-cyclodextrin polymers exhibit rapid water treatment in removing the four low-concentration naphthalene derivatives with convenient regeneration and good reusability.

scholarly journals Zero Net Energy Test House

2011 ◽  
Vol 6 (2) ◽  
pp. 36-48 ◽  
Author(s):  
Timothy L Hemsath ◽  
James D Goedert ◽  
Avery D Schwer ◽  
Yong K Cho
Keyword(s):  
Net Energy ◽  
Solar Panels ◽  
Technological Advances ◽  
Test House ◽  
Zero Net Energy ◽  
New Construction ◽  
Research And Education ◽  
K 12 ◽  
The Impact ◽  
Industry Professionals

This paper describes the first phase of a residential research program to reduce the impact of new construction on the environment through research and education using a Zero Net Energy Test House as a framework. Containing four bedrooms, three and a half baths, the 1,800 square foot house, 1,000 square foot basement, is located in Omaha, Nebraska. It is being used to validate several research projects and provides a platform for applications research of a number of technological advances. Laminated photovoltaic solar panels, a wind turbine, and an occupant monitoring energy control system are some of the sustainable design innovations incorporated. Sustainable features are described that detail the application for LEED Platinum certification. Integrated into several University of Nebraska courses, the house has reached more than 200 students in the past year. Interdisciplinary teaching has involved design, construction, research, monitoring and energy analysis. Education opportunities have reached K–12 students, industry professionals, and public through tours and presentations.

scholarly journals Analysis of the use of photosensitization in human glioblastoma multiforme to induce cell death

2019 ◽  
Vol 98 (Suppl) ◽  
pp. 25-25
Author(s):  
Mario Minor Murakami Junior ◽  
Yollanda E. Moreira Franco ◽  
Maurício Da Silva Baptista ◽  
Suely Kazue Nagahashi Marie
Keyword(s):  
Cell Cycle ◽  
Flow Cytometry ◽  
Methylene Blue ◽  
Cell Proliferation ◽  
Cell Death ◽  
Acridine Orange ◽  
Light Irradiation ◽  
Rt Pcr ◽  
Low Concentration ◽  
The Impact

Introduction: The most frequent primary tumor of the central nervous system is the malignant glioma, being the glioblastoma (GBM), grade IV astrocytoma, the most aggressive and lethal glioma. Malignant astrocytomas are responsive for therapy targeting autophagy as temozolomide, the standard adjuvant treatment which induces autophagic cell death. Autophagy is a homeostatic intracellular process that eliminate old proteins and recycle cellular components. Mitophagy is a subtype of autophagy that regulates the removal of damaged, dysfunctional or redundant mitochondria. Parallel damage against lysosomes and mitochondria membranes using photosensitized oxidations and strong redox stress leads to activation of mitophagy and malfunction of autophagy. This mechanism of photosensitization, ultimately, causes cell death. Challenging cells with a low concentration of a photosensitizer as 1,9-dimethyl methylene blue (DMMB) combined with light- irradiation of 12 joules/cm2 have induced mitochondrial damage with activation of mitophagy and concomitant lysosome damage, in skin-derived cell lines. This experimental design was applied to U87MG GBM cells to verify if tumor cell death may be obtained with combined mitochondrial and lysosomal damages to open new therapeutic strategies for GBM and to better understand the mechanisms of mitophagy.Objectives: Our primary objective is to analyze the impact of challenging GBM cells with a low concentration of 1,9-dimethyl methylene blue (DMMB) with combined light- irradiation of 12 joules/cm2.Methodology: U87MG a human GBM cell line was used. The photodamage was performed using DMMB photosensitized by a LED with maximum emission wavelength at 630 nm providing 12 J/cm2. Cell proliferation and viability assays were performed using MTT to assess whether there was proliferation inhibition and/or alteration of cell viability after photosensitization. Quantification of cells in different stages of apoptosis, and in the various phases of the cell cycle were analyzed using flow cytometry after photosensitization. Acridine orange assay was used to assess lysosome damage. RT-PCR and Western Blotting were performed to evaluate the expression levels of the main autophagy and mitophagy genes and proteins.Partial Results: Cell proliferation and viability assays demonstrated that the concentration of DMMB to cause 50% inhibition of biological activity of cells (IC50) was 10 nM after 48h. The apoptosis and cell cycle experiments were performed in this concentration. Increase in apoptosis was observed after 24hs of photosensitization. Currently, the cell cycle flow cytometry assay has been performed, followed by the quantification of lysosomes damage by Acridine Orange assay. The genes and proteins involved in the mechanisms of autophagy and mitophagy will be determined by expression analysis through RT-PCR and Western blot assays.Discussion and Conclusion: For a future perspective, if this prove of concept is achieved, i.e. death of tumor cells by the combined approach of photosensitizer with irradiation, a new therapeutic strategy of light-activated drugs may be offered to cancer patients.

scholarly journals Impact of Different Photovoltaic Models on the Design of a Combined Solar Array and Pumped Hydro Storage System

2020 ◽  
Vol 10 (10) ◽  
pp. 3650
Author(s):  
Hussein M. K. Al-Masri ◽  
Sharaf K. Magableh ◽  
Ahmad Abuelrub ◽  
Osama Saadeh ◽  
Mehrdad Ehsani
Keyword(s):  
Storage System ◽  
Pso Algorithm ◽  
Energy System ◽  
Solar Array ◽  
Emissions Reduction ◽  
Solar Panels ◽  
Reservoir Volume ◽  
Lower Reservoir ◽  
Whale Optimization ◽  
The Impact

The impact of different photovoltaic models for a combined solar array and pumped hydro storage system was investigated. Al-Wehda dam located in Harta city in the northern of Jordan was used to validate the approach. The two-diode (TD), single-diode (SD), and ideal single-diode (ISD) solar models were evaluated in terms of the solar array size, reliability, and ecological effects. The impoundment of Al-Wehda dam was taken as the upper reservoir of the pumped hydro facility of the proposed renewable energy system. It was found that the PV power is more accurately modelled by considering the recombination loss in the TD solar model. This leads to a more realistic sizing and precise system evaluation. Results were obtained using the particle swarm optimization (PSO) algorithm and the whale optimization algorithm (WOA) for validation purposes. For instance, the PSO results showed that the realistic TD model is reliable, with an index of reliability of 98.558%. Further, it is the most ecological solution with an annual emissions reduction of 21.5198 Gg. The optimized values are 44,840 solar panels and 65.052 M.m3 of the lower reservoir volume for the TD model. The number of PV panels are reduced by 16.67% and 7.93%, respectively, with the ISD and SD relative to the TD model.

scholarly journals Rain concentration and sheltering effect of solar panels on cultivated plots

2018 ◽  
Vol 22 (2) ◽  
pp. 1285-1298 ◽  
Author(s):  
Yassin Elamri ◽  
Bruno Cheviron ◽  
Annabelle Mange ◽  
Cyril Dejean ◽  
François Liron ◽  
...  
Keyword(s):  
Spatial Heterogeneity ◽  
Coefficient Of Variation ◽  
Sharp Decrease ◽  
Field Measurements ◽  
Solar Panels ◽  
Support Tube ◽  
Coefficient Of Uniformity ◽  
Rain Events ◽  
Sheltering Effect ◽  
The Impact

Abstract. Agrivoltaism is the association of agricultural and photovoltaic energy production on the same land area, coping with the increasing pressure on land use and water resources while delivering clean and renewable energy. However, the solar panels located above the cultivated plots also have a seemingly yes unexplored effect on rain redistribution, sheltering large parts of the plot but redirecting concentrated fluxes on a few locations. The spatial heterogeneity in water amounts observed on the ground is high in the general case; its dynamical patterns are directly attributable to the mobile panels through their geometrical characteristics (dimensions, height, coverage percentage) and the strategies selected to rotate them around their support tube. A coefficient of variation is used to measure this spatial heterogeneity and to compare it with the coefficient of uniformity that classically describes the efficiency of irrigation systems. A rain redistribution model (AVrain) was derived from literature elements and theoretical grounds and then validated from experiments in both field and controlled conditions. AVrain simulates the effective rain amounts on the plot from a few forcing data (rainfall, wind velocity and direction) and thus allows real-time strategies that consist in operating the panels so as to limit the rain interception mainly responsible for the spatial heterogeneities. Such avoidance strategies resulted in a sharp decrease in the coefficient of variation, e.g. 0.22 vs. 2.13 for panels held flat during one of the monitored rain events, which is a fairly good uniformity score for irrigation specialists. Finally, the water amounts predicted by AVrain were used as inputs to Hydrus-2D for a brief exploratory study on the impact of the presence of solar panels on rain redistribution at shallow depths within soils: similar, more diffuse patterns were simulated and were coherent with field measurements.

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