scholarly journals Clinical profile of patients with inferolateral myocardial infarction: a comparison study

Author(s):  
Sibaram Panda ◽  
Sunil Kumar Jena ◽  
Uttam Kumar Pattanaik

Background: Patient with lateral wall changes in inferior wall myocardial infarction (MI) usually ignored most often. However above lateral MI changes in the clinical setting of inferior wall MI usually impact on final clinical outcome and prognosis of the patients. Our aim of the study is observe diversity in clinical profile of inferolateral MI in comparison to patient with inferior wall without any lateral wall MI changes.Methods: Current study enrolled 405 patients admitted to cardiology emergency with inferior wall MI. Patients divided into three groups on the basis of ECG changes, inferolateral (group A), isolated inferior wall MI (group B) and inferior wall MI with RVMI (group C). Patients with RVMI (group C) excluded from the group. Clinical profile and outcomes compared between group A and B.Results: Around 33.8% pts with inferior wall STEMI have ECG changes of lateral wall AMI. STEMI equivalent in lead V1, V2 which is the most common ECG presentation, seen in 65% inferolateral patients. 45.7% of population of inferolateral MI are above age group of 60 years. 66.2 % of the patients with inferolateral MI having two or more risk factors. Dyspnoea is one of common symptom seen in 29.9% patients. Statistically significant number of patients in inferlateral MI have clinical picture of LVF (crepitation, S3), higher Killip class as compared to inferior wall MI. Incidence of complications like LVF, MR, VT, death is significantly higher in this group.Conclusions: Around 1/3rd patient with lateral MI changes seen in inferior wall MI patients. STEMI equivalent changes in anterior precordial leads are most common ECG presentation. More no patients are older and with multiple risk factors. Complication and death are higher in this group. So meticulous attention should be given to patients with lateral wall MI changes in inferior wall MI. 

2018 ◽  
Vol 5 (1) ◽  
pp. 96
Author(s):  
Manohar Shankarrao Chavan ◽  
M. Bhaktavatsalam

Background: New cases of AMI tell us about the prevalence of risk factors in the community which lead to increased incidence of AMI. On the other hand, the occurrence of repeated attacks of AMI tells us about the quality of care received by the patient during the attack of AMI and its subsequent treatment. The objective was to study of risk factors and clinical profile of patients with acute myocardial infarction.Methods: Present hospital based cross sectional study was carried out for a period of two years among 50 eligible subjects selected as per the inclusion and exclusion criteria laid down for the conduct of the present study to study the clinical profile and risk factors.Results: The commonest age group was 61-70 years (36%). The average age of the patient in the study group was 53.88 years. The male patient dominated the study group. This male to female ratio need not necessarily indicate the epidemiological frequency of myocardial infarction. The most common MI in the present study group was inferior wall MI (46%). 18 (36%) were smokers, 20 patients (40%) among 50 patients presented with complications. Of them 13 patients had arrhythmias (26%).Conclusions: The most commonly affected were elderly. AMI was more common in the males. Inferior wall myocardial infarction was the common lesion seen in the present study. Among the risk factors, smoking was the most common risk factor found in the present study.


2006 ◽  
Vol 124 (4) ◽  
pp. 186-191 ◽  
Author(s):  
Afonso Celso Pereira ◽  
Roberto Alexandre Franken ◽  
Sandra Regina Schwarzwälder Sprovieri ◽  
Valdir Golin

CONTEXT AND OBJECTIVE: There is uncertainty regarding the risk of major complications in patients with left ventricular (LV) infarction complicated by right ventricular (RV) involvement. The aim of this study was to evaluate the impact on hospital mortality and morbidity of right ventricular involvement among patients with acute left ventricular myocardial infarction. DESIGN AND SETTING: Prospective cohort study, at Emergency Care Unit of Hospital Central da Irmandade da Santa Casa de Misericórdia de São Paulo. METHODS: 183 patients with acute myocardial infarction participated in this study: 145 with LV infarction alone and 38 with both LV and RV infarction. The presence of complications and hospital death were compared between groups. RESULTS: 21% of the patients studied had LV + RV infarction. In this group, involvement of the dorsal and/or inferior wall was predominant on electrocardiogram (p < 0.0001). The frequencies of Killip class IV upon admission and 24 hours later were greater in the LV + RV group, along with electrical and hemodynamic complications, among others, and death. The probability of complications among the LV + RV patients was 9.7 times greater (odds ratio, OR = 9.7468; 95% confidence interval, CI: 2.8673 to 33.1325; p < 0.0001) and probability of death was 5.1 times greater (OR = 5.13; 95% CI: 2.2795 to 11.5510; p = 0.0001), in relation to patients with LV infarction alone. CONCLUSIONS: Patients with LV infarction with RV involvement present increased risk of early morbidity and mortality.


2021 ◽  
Vol 11 (2) ◽  
pp. 148-150
Author(s):  
Sapkal Harish Barsu ◽  

Background: There is a rising incidence of acute myocardial infarction (MI) in young adults. It is important to identify and control cardiovascular risk factors at an early age to prevent the incidence in cases of young MI. Aim: To study the clinical profile of acute myocardial infarction in young patients. Material and Methods: Patients aged 40 years or younger admitted to with a diagnosis of acute MI were studied for clinical presentations, risk factors and management outcome. Results: Majority of patients presented with typical chest pain. 5 patients presented with atypical symptoms, one had only sweating, two had heaviness of chest, one had epigastric pain, one had sudden collapse. The most common risk factor was smoking in 68% followed by alcoholism 40%, Obesity 38%, Metabolic syndrome 38%, HTN 28% DM 26%. Of the total 50 patients, 47 (94%) patients survived whereas 3 (6%) patients succumb to death. Conclusion: There is a need to increase awareness among the young population regarding the entity of MI in young hence stressing on modifying life style. This simple measure can make a large difference in preventing the occurrence of MI in young.


2020 ◽  
Vol 17 (1) ◽  
pp. 7-16
Author(s):  
Chandra Mani Adhikari ◽  
Kiran Prasad Acharya ◽  
Reeju Manandhar ◽  
Kunjang Sherpa ◽  
Rikesh Tamrakar ◽  
...  

Background and Aims: Incidence of ST-elevation myocardial infarction (STEMI) is increasing in Nepal. We aim to describe the presentation, management, complications, and outcomes of patients admitted with a diagnosis of STEMI in Shahid Gangalal National Heart Centre (SGNHC), Nepal. Methods: Shahid Gangalal National Heart Centre-ST-elevation registry (SGNHC-STEMI) registry was a cross sectional, observational, registry. All the patients who were admitted with the diagnosis of STEMI from January 2018 to December 2018 were included. Results: In this registry, 1460 patients out of 1486 patients who attended emergency were included. The mean age of patients was 60.8±13.4 years (range: 20 years to 98 years) with 70.3% male patients. Most of the patients (83.2%) were referred from other hospitals and 16.8% of patients directly attended the SGNHC emergency. During the presentation, smoking (54%) was the most common risk factor, followed by hypertension (36.6%), diabetes mellitus (25.3%), and dyslipidemia (7.8%). After admission, new cases of dyslipidemia, HTN, Impaired Fasting Glucose (IFG), and Type 2 DM were diagnosed in 682 (51.3%), 182 (20.1%), 148 (10.3%) and 95 (8.9%) respectively. At the time of presentation, 73.3% were in Killip class I and 26.3% were above Killip class II with 5.1% in cardiogenic shock. Thirty-one percent of the cases received reperfusion therapy (Primary percutaneous intervention in 25.2% and fibrinolysis in 5.8%). Inferior wall MI was the most common type of STEMI. Among the patients who underwent invasive therapy, the multi-vessel disease was noted in 46.2% cases and left main coronary artery involvement in 0.7% cases. In-hospital mortality was 6.2% with cardiogenic shock being the most common cause. Aspirin (97.8%), clopidogrel (96.2%), statin (96.4%), ACEI/ARB (76.8%) and beta-blocker (76.8%) were prescribed during discharge. Conclusion: The SGNHC-STEMI registry provides valuable information on the overall aspect of STEMI in Nepal. In general, the SGNHC-STEMI registry findings are consistent with other international data.


2017 ◽  
Vol 56 (4) ◽  
pp. 236-243
Author(s):  
Sokol Myftiu ◽  
Enxhela Sulo ◽  
Genc Burazeri ◽  
Bledar Daka ◽  
Ilir Sharka ◽  
...  

AbstractBackgroundThe clinical profile of acute myocardial infarction (AMI) patients reflects the burden of risk factors in the general population. Differences between incident (first) and recurrent (repeated) events and their impact on treatment are poorly described. We studied potential differences in the clinical profile and in-hospital treatment between patients hospitalised with an incident and recurrent AMI.MethodsA total of 324 patients admitted in the Coronary Care Unit of ‘Mother Teresa’ hospital, Tirana, Albania (2013-2014), were included in the study. Information on AMI type, complications and risk factors was obtained from patient’s medical file.Logistic regression analyses were used to explore differences between the incident and recurrent AMIs regarding clinical profile and in-hospital treatment.ResultsOf all patients, 50 (15.4%) had a prior AMI. Compared to incident cases, recurrent cases were older (P=0.01), more often women (P=0.01), less educated (P=0.01), and smoked less (P=0.03). Recurrent cases experienced more often heart failure (HF) (OR=2.48; 95% CI: 1.31–4.70), impaired left ventricular ejection fraction (OR=1.97; 95% CI:1.05–3.71), and multivessel disease (OR=6.32; 95% CI: 1.43–28.03) than incident cases. In-hospital use of beta-blockers was less frequent among recurrent compared to incident cases (OR=0.45; 95% CI: 0.24–0.85), while no statistically significant differences between groups were observed regarding angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, statin, aspirin or invasive procedures.ConclusionA more severe clinical expression of the disease and underutilisation of treatment among recurrent AMIs are likely to explain their poorer prognosis compared to incident AMIs.


2020 ◽  
Vol 12 (1) ◽  
pp. 63-68 ◽  
Author(s):  
Soraya Siabani ◽  
Patricia M Davidson ◽  
Maryam Babakhani ◽  
Nahid Salehi ◽  
Yousef Rahmani ◽  
...  

Introduction: This study aimed to evaluate the in-hospital mortality of patients with ST-segment elevation myocardial infarction (STEMI), according to gender and other likely risk factors.<br /> Methods: This study reports on data relating to 1,484 consecutive patients with STEMI registered from June 2016 to May 2018 in the Western Iran STEMI Registry. Data were collected using a standardized case report developed by the European Observational Registry Program (EORP). The relationship between in-hospital mortality and potential predicting variables was assessed multivariable logistic regression. Differences between groups in mortality rates were compared using chi-square tests and independent t-tests. <br /> Results: Out of the 1484 patients, 311(21%) were female. Women were different from men in terms of age (65.8 vs. 59), prevalence of hypertension (HTN) (63.7% vs. 35.4%), diabetes mellitus (DM) (37.7% vs. 16.2%), hypercholesterolemia (36.7% vs. 18.5%) and the history of previous congestive heart failure (CHF) (6.6% vs. 3.0%). Smoking was more prevalent among men (55.9% vs. 13.2%). Although the in-hospital mortality rate was higher in women (11.6% vs. 5.5%), after adjusting for other risk factors, female sex was not an independent predictor for in-hospital mortality. Multivariable analysis identified that age and higher Killip class (≥II) were significantly associated with in-hospital mortality rate.<br /> Conclusion: In-hospital mortality after STEMI in women was higher than men. However, the role of sex as an independent predictor of mortality disappeared in regression analysis. The gender based difference in in-hospital mortality after STEMI may be related to the poorer cardiovascular disease (CVD) risk factor profile of the women.


2020 ◽  
pp. 1-2
Author(s):  
MS Revathy ◽  
Monali Nistane ◽  
Manimaran M ◽  
Sumati B

Background: Colorectal cancer (CRC) incidence and mortality rates vary markedly around the world with low reported cases in India. It is a lethal disease with high mortality. It has varied presentation from asymptomatic, anaemia, altered bowel habits to frank bleeding per rectum, intestinal obstruction. There are very few studies in India describing the clinical profile and risk factors of CRC. Objective: To study Clinical profile and risk factors in patients with colorectal cancer. Methods: A prospective single center study was conducted from August 2018 to August 2019. It included all patients who were newly diagnosed CRC. Their demographic profile, site of lesion, clinical presentations, risk factors, colonoscopic findings, histology of the lesion, biochemical analysis and imaging were performed. Results: 32 patients with newly diagnosed CRC were evaluated. Mean age was 52.4 years. Male to female ratio was 1.5:1. Overall fatigue was the most common symptom (87.5%) followed by per rectal bleeding (37.5%). Fatigue was the most common symptom with right sided CRC while per rectal bleeding was the most common symptom with rectal CRC. Low fiber diet was most common risk factor (71.9%). Histologically adenocarcinoma was the most common type (90.6%). Conclusion: Rectum was the most common site and adenocarcinoma was the most common histological type. Low fiber diet was the most common risk factor. Majority of the patients had localized or locally advanced disease observed in our study.


2021 ◽  
pp. 102-111
Author(s):  
Musdalifah Eka Pratiwi ◽  
Mutmainnah Mutmainnah

Hypertension is an increase in blood flow pressure that occurs in the human body which is one of the most common diseases found, according to the NHLBI (National Heart, Lung, and Blood Institute), 1 in 3 patients suffering from hypertension have risk factors for myocardial infarction, stroke, acute kidney failure and also death. The purpose of this study was to determine the description of the characteristics of hypertension patients in Pertiwi Makassar Health Center. This research was conducted on all patients diagnosed with hypertension at the Pertiwi Puskesmas in September 2019. The study was conducted with a descriptive study using an observational approach to see a description of the characteristics of hypertensive patients at the Pertiwi Puskesmas. These characteristics include age, sex and body mass index. From 134 people it can be seen that the number of male patients with hypertension is 55 people (41.04%) and the number of female patients with hypertension is 79 people (58.95%). The number of patients aged <40 years, amounting to 5 people (3.73%), the number of patients aged 40-45 years which amounted to 4 people (2.98%), the number of patients aged 46-50 years which amounted to 11 people (8.20 %), and the number of patients> 50 years old totaling 114 people (85.07%). The number of hypertensive patients who are underweight is 2 people (1.49%), the number of normal hypertension patients is 41 people (30.59%), the number of hypertensive patients who are overweight is 42 people (31.34%), the number of hypertensive patients who are Obese I is 48 people (35.82%) and the number of hypertensive patients who are Obesity II is 2 people (1.49%). Based on the results of the study it was found that women are more at risk of developing hypertension than men, aged> 50 years more than other ages and hypertensive patients are far more classified as obese I nutritional status.


QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
M M Halim ◽  
D A Kamal ◽  
A M Onsy ◽  
M M Rayan

Abstract Background Myocardial Infarction carries a significant morbidity, psychological effects, and financial constraints for the patient and the family when it occurs at young age. However there is limited data on the clinical features of young adults with AMI in Egypt and the Middle Eastern region. We therefore sought to investigate the clinical profile, risk factors and angiographic variables of this age group in Egypt. Aim of the Work To determine the clinical profile and prevalence of different risk factors including Cigarette Smoking, Tramadol use, Cannabis smoking, HDL & LDL levels, stressful lifestyle and bad sleeping habits in Egyptian patients presented with Myocardial Infarction for the first time at age ≤45 years. Methods We conducted a cross sectional observational study on 106 consecutive patients aged ≤45 years admitted with 1st time myocardial infarction in the period between February 2018 and August 2018 at Ain Shams University, Egypt. Clinical, and Angiographic variables were recorded from all patients. Results Out of 1207 patients admitted with 1st time MI, 106 were young that gave a prevalence of 8.8% in our center. Out of 106 patients, 101 were male. Mean age was 39.19 yrs. 71 patients had ST elevation myocardial infarction (MI) (67%) and 35 had non ST elevation MI (33%). Anterior wall MI was present in 49 patients (46.2%), inferior wall MI in 20 patients (18.9%) and lateral wall MI in 2 patients (1.9%). 93 patients (88%) were smokers, 31 patients (29.2%) were Tramadol users, 43 patients(40.6%) smoked cannabis, 50 patients (47.2%) had bad sleeping habits, 29 patients (27.4%) had high stress levels, 37 patients (34.9%) were hypertensive, 22 patients were diabetic (20.8%). Family history of CAD was present in 20 (18.9%) patients. Low High-density lipoprotein (HDL) was seen in 47 patients (44.3%), and high Low-density lipoprotein in 20 patients (18.9%). LAD was involved in 56% of patients, with a significant association between Tramadol use and LAD involvement. We found significant association between both Tramadol use and Cannabis smoking and the presence of Heavy thrombus burden in Coronary Angiography. Conclusion AMI in the young almost exclusively occurs in male, Anterior wall MI is most common, with LAD being involved in around half of patients. Smoking, hypertension, low HDL, Tramadol use, Cannabis smoking, and bad sleeping habits are the major risk factors. Tramadol use was associated with significant affection of LAD. Tramadol use and Cannabis smoking were associated with high thrombus burden on coronary angiography,


2021 ◽  
Vol 18 (1) ◽  
pp. 33-37
Author(s):  
Pradeep Thapa ◽  
Prakash Aryal ◽  
Rajani Baniya

Background and Aims: ST-Elevation Myocardial Infarction (STEMI) is a leading cause of morbidity and mortality. This study aims to summarize the clinical profile and complications of patients with STEMI in a teaching hospital. Methods: This was a prospective hospital based descriptive and observational study conducted at College of Medical Sciences Teaching Hospital (CoMSTH), Bharatpur from January 2017 to July 2018 in 110 patients with a diagnosis of acute STEMI. Results: Out of 110 patients the mean age of presentation was 59.31 years and 64.5% were male. Typical chest pain (90%) was the most common presenting symptom and 45.5% patients presented within six hours of chest pain. Most common traditional risk factors were hypertension and smoking which were present in 44 (40%) cases, followed by diabetes in 33 (30%), dyslipidemia in 22 (20%). Majority of patients (49.1%) were in killips class I, and only 9 (8.2%) patients were in cardiogenic shock (killips class IV). Inferior wall was the most common in 30% patients followed by anteroseptal wall MI (23.6%), anterior wall MI (11.8%) and combined (anterior and inferior) in 10%. Revascularization with primary Percutaneous Coronary Intervention (PCI) was done in 46 (41.8%) patients, thrombolysis was done in 41 (37.3%) patients. Arrhythmias (39.1%) followed by heart failure (24.5%) were the common complications. The overall in-hospital mortality was 16 (14.5%). Conclusions: Patients with acute STEMI at College of Medical Sciences Teaching Hospital (CoMSTH) were predominantly male with hypertension and smoking as the commonest risk factors. Arrhythmias were the most common complications and in-hospital mortality rate was 14.5%.


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