scholarly journals Comparison of Nitroglycerin versus Lignocaine Spray to Attenuate Haemodynamic Changes in Elective Surgical Patients Undergoing Direct Laryngoscopy and Endotracheal Intubation: A prospective randomised study

2019 ◽  
Vol 19 (4) ◽  
pp. 316
Author(s):  
Rohit K. Varshney ◽  
Mukesh K. Prasad ◽  
Megha Garg
Keyword(s):  
Blood Pressure ◽  
Endotracheal Intubation ◽  
Direct Laryngoscopy ◽  
Pressor Response ◽  
Surgical Patients ◽  
Rate Pressure Product ◽  
Control Group ◽  
Control Groups ◽  
Treatment Groups ◽  
And Control

Objectives: This study aimed to compare the effects of nitroglycerin (NTG) versus lignocaine spray in blunting the pressor response during direct laryngoscopy and endotracheal intubation. Methods: This study was conducted between January and June 2018 in the Department of Anesthesiology, Teerthankar Mahaveer Medical College, Moradabad, India. A total of 90 elective surgical patients of American Society of Anesthesiologists physical status grades I or II were divided into three groups, comprising two treatment groups and one control group. Patients in the treatment groups received either one puff (1.5 mg/kg) of lignocaine 10% spray or one puff (400 μg) of NTG spray in the oropharynx one minute prior to the induction of anaesthesia. Haemodynamic variables and mean rate pressure product at baseline and one, two, three, four and five minutes post-induction were compared. Results: There was a significant reduction in mean heart rate at 3–5 minutes in both treatment groups compared to the control group (P <0.050), as well as lower increases in mean arterial pressure at 1–3 minutes (P <0.050). However, at 2–4 minutes, there was a significantly greater decrease in mean systolic blood pressure in the NTG group compared to both the lignocaine and control groups (P <0.050). Moreover, a greater decrease in mean rate pressure product response at 1–5 minutes was observed in the NTG group compared to the lignocaine and control groups (P = 0.001). Conclusion: The NTG spray was more effective than lignocaine in attenuating blood pressure increases and rate pressure product during elective laryngoscopy and intubation.Keywords: Endotracheal Anesthesia; Intubation; Laryngoscopy; Lignocaine; Nitroglycerin; Comparative Effectiveness Research; India.

scholarly journals Pengaruh Terapi AIUEO terhadap Kemampuan Bicara Pasien Stroke yang Mengalami Afasia Motorik

2019 ◽  
Vol 1 (2) ◽  
pp. 226-235
Author(s):  
Afnijar Wahyu ◽  
Liza Wati ◽  
Murad Fajri
Keyword(s):  
Wilcoxon Test ◽  
Control Group ◽  
Stroke Patients ◽  
Control Groups ◽  
Control Group Design ◽  
Treatment Groups ◽  
Group Design ◽  
Motor Aphasia ◽  
A Value ◽  
And Control

The purpose of this study was to determine the effect of AIUEO therapy on the speech ability of stroke patients who have motor aphasia in Raja Ahmad Thabib Hospital Tanjungpinang. The research design used was quasi experiment with the Nonequivalent Control Group Design approach to 9 respondents who were divided into 9 treatment groups and 9 control groups. The results showed that there were significant differences in the functional ability of communication between the control and treatment groups with a value of p <0.05 (p = 0.007 at a = 0.05) using the Wilcoxon Test statistical test. Conclusion, the influence of AIUEO therapy on the speech ability of stroke patients with motor aphasia in the treatment and control groups at Ahmad Thabib Hospital Tanjungpinang.   Keywords: Speech Ability, Motor Aphasia Stroke, AIUEO Therapy

scholarly journals Investigation of the effect of the virtual reality application on experimental pain severity in healthy

2019 ◽  
Vol 65 (3) ◽  
pp. 446-451
Author(s):  
Dilek Karaman ◽  
Funda Erol ◽  
Dilek Yılmaz ◽  
Yurdanur Dikmen
Keyword(s):  
Blood Pressure ◽  
Virtual Reality ◽  
Control Group ◽  
Control Groups ◽  
Adult Type ◽  
Significant Difference ◽  
The Mean ◽  
And Control ◽  
Experimental Group ◽  
Virtual Reality Application

SUMMARY OBJECTIVE: This study aimed to investigate the effect of virtual reality application on experimental ischemic pain created with a blood pressure instrument in healthy volunteers. METHODS: The research sample consisted of 172 volunteer adult students who conformed to the inclusion criteria. These individuals were assigned into an experimental (n=86) and a control group (n=86) by a simple randomization method. All individuals in the experimental and control groups wereexperimentally subjected to pain for two minutes by applying 260 mmHg of pressure 3-4 cm above the antecubital region of the left arm with an aneroid adult-type blood pressure instrument. During the procedure, the volunteers in the experimental group watched virtual reality images, while those in the control group received no intervention. Immediately after the procedure, the pain levels of the individuals in both groups were assessed with a Visual Analog Scale (VAS). RESULTS: We found that the mean pain score of the individuals in the experimental group was 2.62±1.82, and that of individuals in the control group was 5.75±1.65. Results of the statistical analysis showed a statistically significant difference between the mean pain scores of the individuals in the experimental and control groups (p<0.001). CONCLUSION: This study found that the use of virtual reality was effective in reducing the level of pain in healthy individuals. This method used a smartphone with widespread availability and ease of transportation, which can be used by health professionals as a non-pharmacological method in the management of pain.

scholarly journals Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Hongyan Chen ◽  
Jianping Dai ◽  
Xiaozhe Zhang ◽  
Kai Wang ◽  
Shuhua Huang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular System ◽  
Acupuncture Treatment ◽  
Bodily Pain ◽  
Brain Network ◽  
Control Group ◽  
Control Groups ◽  
Short Term ◽  
Sf 36 ◽  
And Control

The present study attempted to explore modulated hypothalamus-seeded resting brain network underlying the cardiovascular system in primary hypertensive patients after short-term acupuncture treatment. Thirty right-handed patients (14 male) were divided randomly into acupuncture and control groups. The acupuncture group received a continuous five-day acupuncture treatment and undertook three resting-state fMRI scans and 24-hour ambulatory blood pressure monitoring (ABPM) as well as SF-36 questionnaires before, after, and one month after acupuncture treatment. The control group undertook fMRI scans and 24-hour ABPM. For verum acupuncture, average blood pressure (BP) and heart rate (HR) decreased after treatment but showed no statistical differences. There were no significant differences in BP and HR between the acupuncture and control groups. Notably, SF-36 indicated that bodily pain (P= 0.005) decreased and vitality (P= 0.036) increased after acupuncture compared to the baseline. The hypothalamus-related brain network showed increased functional connectivity with the medulla, brainstem, cerebellum, limbic system, thalamus, and frontal lobes. In conclusion, short-term acupuncture did not decrease BP significantly but appeared to improve body pain and vitality. Acupuncture may regulate the cardiovascular system through a complicated brain network from the cortical level, the hypothalamus, and the brainstem.

scholarly journals Giving Watermelon Juice on the Reduction of Blood Pressure of Young Adult Hypertension

2020 ◽  
Vol 2 (3) ◽  
pp. 135-146
Author(s):  
Nurjannah Nurjannah
Keyword(s):  
Blood Pressure ◽  
Systolic Pressure ◽  
Sampling Technique ◽  
Control Group ◽  
Control Groups ◽  
Control Group Design ◽  
Watermelon Juice ◽  
Before And After ◽  
Pressure Lowering ◽  
And Control

The incidence of hypertension in Southeast Sulawesi tends to increase each year. Many people with hypertension are tired of taking blood pressure-lowering drugs because they are addictive and have side effects. The objective of the study was to understand the effect of watermelon juice supplementation to decrease blood pressure on early adult hypertension sufferers in the working area of the Public Health Center of Poasia Kendari city. This study was a true experiment through pretest-posttest with a control group design. The sample size was 30 people who were determined by purposive sampling technique and was allocated by matching within 15 people for both treatment and control groups. The statistical test result showed that there were different blood pressure both systolic and diastolic blood pressures before and after receiving watermelon juice supplementation for 7 days with the dose was twice 350/gr/glass/day on treatment group with significance value ρ = 0,000 (α = 0,05). Meanwhile, for the control group, there was no different blood pressure before and after receiving supplementation with significance value ρ = 1,000 (α = 0,05) for systolic pressure and ρ = 0,499 for diastolic one. There was different blood pressure after receiving watermelon juice supplementation between treatment and control groups with significance value ρ =0,031 (α = 0,05) for systolic pressure and p = 0,012 for diastolic one. Hence, it’s concluded that there was a significant effect of watermelon juice supplementation to decrease the blood pressure on early adult hypertension sufferers. 

scholarly journals Safety and Efficacy of Ginkgo-Damole and Nitroglycerin or Sodium Nitroprusside on Hypertensive Cerebropathies: A Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Li Peng ◽  
Wei-kun Zhao ◽  
Tong-tong Xu ◽  
Qi Wu ◽  
Pan Lu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Sodium Nitroprusside ◽  
Meta Analysis ◽  
Control Group ◽  
Clinical Effects ◽  
Observation Group ◽  
Control Groups ◽  
Safety And Efficacy ◽  
Significant Difference ◽  
And Control

Objective. To systematically evaluate the safety and efficacy of ginko-damole combined with nitroglycerin or unitary sodium nitroprusside on hypertensive cerebropathy. Methods. Four Chinese databases (VIP, CBM, Wanfang database, and CNKI database) and three English databases (Cochrane, PubMed, and EMBASE) were used to screen randomised controlled trials (RCTs) on treatments of hypertensive cerebropathy using both ginko-damole and nitroglycerin or unitary sodium nitroprusside. Outcomes included clinical effect, blood pressure after treatment, and adverse effects. These indicators were then analysed statistically using the RevMan 5.3 and Stata 12.0 software. Results. Altogether, 16 RCTs including 1507 patients with hypertensive cerebropathy were included in the present meta-analysis, of which, 755 patients treated with combined ginko-damole and nitroglycerin were included in the observation group and 752 patients treated with sodium nitroprusside were included in the control group. The curative effect of the observation group was significantly better than that of the control group (RR: 1.115 [1.077, 1.155], p<0.05). DBPs of the observation and control groups were both lower after treatment, and no significant difference was observed between the observation and control groups (MD: −1.072 [−2.578, 0.434], p>0.05). SBPs in the observation group were significantly lower than those in the control group (MD: −2.842 [−5.222, −0.462], p<0.05). The probability of adverse response in both groups did not differ significantly (RR: 0.752 [0.412, 1.374], p>0.05). Conclusion. Compared with sodium nitroprusside, the combined ginkgo-damole and nitroglycerin could better control blood pressure in patients with hypertensive cerebropathy and showed enhanced clinical effects and improved safety. However, due to poor quality of the included studies, results of the present meta-analysis should be confirmed by more stringent RCTs.

Effect of biochemical profiles and reproductive performance during internal parasites in Goat and Sheep

2017 ◽  
Vol 2 (01) ◽  
pp. 103-109
Author(s):  
Dinesh Mahto
Keyword(s):  
Control Group ◽  
Control Groups ◽  
Treatment Groups ◽  
Group I ◽  
Internal Parasites ◽  
Mineral Mixture ◽  
Biochemical Profiles ◽  
Group Ii ◽  
Minimum Interval ◽  
And Control

Gastrointestinal parasitic infected ewes and does were kept almost parasite free for about 3 months using Albendazole alone or supplemented with mineral mixture. The Hb (g/dl) level ranged from 8.83±0.08 to 8.96±0.03 in ewes and does was 8.78±0.02 to 8.95±0.24 before treatment. The level of Hb increased significantly (P less than 0.01) in both the treatment groups after treatment on day 20.The Serum level of Ca, P, Cu and Zn in ewes and does increased significantly after treatment on day 20 in both the treatment groups as comparison to control group. Although they did not vary significantly among themselves except the level of Cu which was significantly (P less than 0.01) higher in group II than the group I in ewes and does. The level of Zn was higher in group I than group II in does. The minimum interval from treatment to onset of estrus were recorded in group II , 41 days in ewes and 43 days in does which was followed by group I 44 days in ewes and 46 days in does and control group 55 days in ewes and 52 days in does. The average required number of services per conception in does were 1.33, 1.00 and 2.00 for I, II and control groups, respectively. The corresponding values in ewes were 1.67, 1.17 and 2.17, respectively. The pregnancy rates in the three groups were 66.66, 83.33 and 33.33%, respectively in case of does. The corresponding values in ewes were 50.00, 66.66 and 33.36%, respectively.

Efficacy of Imagery and Meditation Techniques in Treating Psoriasis

1989 ◽  
Vol 8 (1) ◽  
pp. 25-38 ◽  
Author(s):  
Louise Gaston ◽  
Jean-Charles Crombez ◽  
Jacques Joly ◽  
Sheilagh Hodgins ◽  
Marc Dumont
Keyword(s):  
Time Series ◽  
Multivariate Regression ◽  
Multivariate Regression Analysis ◽  
Control Group ◽  
Control Groups ◽  
Treatment Groups ◽  
Series Design ◽  
Significant Difference ◽  
The Mean ◽  
And Control

Using a dismantled time-series design, eighteen subjects were randomly assigned to three groups: meditation ( N = 5); meditation and imagery ( N = 4); waiting list ( N = 5). Treatment lasted twelve weeks, while pre- and post-baseline periods were of four weeks. An assessment control group control was also used during baseline periods ( N = 4). The severity of psoriasis symptoms was reliably rated by dermatologists. While controlling for extraneous factors influencing psoriasis symptoms, a time-series multivariate regression analysis revealed a significant difference between the mean psoriasis ratings of treatment and control groups after treatment (partial r = .30, p < .01). No additional impact was associated with the use of the imagery technique (partial r = − .06, p > .05). Four subjects in the treatment groups, two in each condition, succeeded in clinically improving their psoriasis symptoms, and none deteriorated. The practice of mediation may be clinically effective for some patients in reducing their psoriasis symptoms.

Comparison of Students Taught Basketball Skills Using Mastery and Nonmastery Learning Methods

1992 ◽  
Vol 11 (3) ◽  
pp. 235-247 ◽  
Author(s):  
Connie L. Blakemore ◽  
H. Gill Hilton ◽  
Joyce M. Harrison ◽  
Tracy L. Pellett ◽  
James Gresh
Keyword(s):  
Instructional Strategy ◽  
Mastery Learning ◽  
Control Group ◽  
Psychomotor Skills ◽  
Control Groups ◽  
Treatment Groups ◽  
Competitive Game ◽  
Game Situation ◽  
Significant Difference ◽  
And Control

Mastery learning is an instructional strategy that embraces the philosophy that almost any student can learn what is being taught given sufficient time and help. Through Bloom’s group-based, teacher-paced model, 71 seventh-grade boys were taught basketball skills. Students in two treatment groups (mastery and nonmastery) and a control group were compared on the performance of psychomotor skills in isolation and in a competitive game situation before, midway through, and following their training. Students in the mastery group were not taught new skills until 80% had mastered the present skills. The mastery group performed significantly better on isolated skills than did the nonmastery and control groups. There was no significant difference between groups in the performance of skills in a competitive game situation.

scholarly journals Pengaruh Do’a terhadap Tekanan Darah pada Pasien Gagal Ginjal Kronis (GGK) Pre-Hemodialysis

2018 ◽  
Vol 2 (1) ◽  
pp. 343-355
Author(s):  
Hilda Nur Afriani ◽  
Rohman Azzam ◽  
Busrja M.Nur
Keyword(s):  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Reduce Blood Pressure ◽  
T Test ◽  
Control Group ◽  
Test Results ◽  
Hospital Data ◽  
Control Groups ◽  
Before And After ◽  
And Control

Objective of this study was to determine the effect of prayer on pre-hemodialysis blood pressure of CRF patients in the hemodialysis room of the Jakarta Islamic Hospital. Data collection was done through purposive sampling. This study examined 32 respondents. The results of the study indicated there was a decrease in blood pressure in the intervention and control groups before and after giving prayers on systolic and diastolic blood pressure. The results of the paired t-test before and after being given prayers in the intervention and control groups produced a sig value of <0.05 in systolic and diastolic blood pressure, which means that there were differences before and after giving prayers. The unpaired t-test results in the intervention and control groups of systolic blood pressure produced a sig value> 0.05, which means that there was no difference between the intervention and control group. On the contrary, diastolic blood pressure produced a sig value <0.05, which means that there were differences between the intervention and control group. Finally, it can be concluded that the provision of a prayer intervention in pre-hemodialysis was effectively proven to reduce blood pressure. Keywords : chronic kidney disease, blood pressure, prayer.

296 EFFECT OF GnRH AND ESTRADIOL BENZOATE INJECTION ON SUPEROVULATORY RESPONSE IN EARLY POSTPARTUM SUCKLING JAPANESE BLACK COWS

2009 ◽  
Vol 21 (1) ◽  
pp. 245
Author(s):  
K. Oshima ◽  
Y. Ochiai ◽  
T. Kojima ◽  
N. Yamamoto
Keyword(s):  
Embryo Quality ◽  
Estradiol Benzoate ◽  
Control Group ◽  
Control Groups ◽  
Treatment Groups ◽  
Early Postpartum ◽  
Uterine Flushing ◽  
Days Open ◽  
And Control ◽  
Estrous Behavior

The objective of this study was to investigate the effect of GnRH and EB injection on the SOV response in early postpartum suckling Japanese Black cows. Forty-eight cows were included in this study. All cows received a controlled internal-drug-releasing device containing 1.9 g progesterone (CIDR; Easi-Breed; InterAg, Hamilton, New Zealand) at 40 days postpartum, and were subsequently superstimulated with a total dose of 20 armour units FSH (Antrin 40; Kawasaki-Mitaka, Kanagawa, Japan) twice daily, with gradually decreasing doses from day 45 till day 47. CIDR was withdrawn with 0.75 mg of cloprostenol (Estrumate; Nagase Medicals, Itami, Japan) injection at day 47. After FSH treatment, the cows were assigned to 3 groups: (1) 100 μg GnRH (Conceral; Nagase Medicals) injection at day 49 (GnRH, n = 19), (2) 2 mg EB (Kawasaki-Mitaka) injection at day 48 (EB, n = 15), and (3) control (n = 14). AI was carried out twice based on the estrous behavior of the cows, which was examined several times daily. Embryos were nonsurgically collected 7 to 8 days after estrus. The ovaries were examined by ultrasonography, and the number of CL and unovulated follicles (UF) were counted. After uterine flushing, the cows were re-employed for reproductive purposes. The intervals to first estrus after flushing and days open were examined. Blood samples were collected temporally, and concentrations of progesterone (P4) and estradiol (E2) were measured. The ovaries were examined by ultrasonography and the number of CL, small follicles (<5 mm in diameter), medium follicles (between 5 and 10 mm in diameter), and large follicles (>10 mm in diameter) were counted temporally. Data were analyzed by GLM and Dunnett’s T3 test. There were no significant differences between both treatment groups and the control group in the number of CL (15.2 ± 6.8, 18.9 ± 9.4, and 14.9 ± 8.9 in the GnRH, EB, and control groups, respectively; mean ± SD), UF (5.3 ± 3.2, 4.7 ± 3.2, and 7.2 ± 9.5, respectively), recovered ova or embryos (11.4 ± 8.1, 11.1 ± 8.9, and 11.1 ± 9.1, respectively), transferable embryos (6.8 ± 5.3, 7.5 ± 7.6, 7.2 ± 6.7, respectively), and freezable embryos (6.3 ± 5.6, 6.6 ± 7.9, and 5.7 ± 6.1, respectively). Furthermore, there were no significant differences in the intervals to first estrus after flushing and days open (12.7 ± 13.6 and 90.0 ± 23.1 in the GnRH, 8.6 ± 5.3 and 79.1 ± 20.1 in the EB, and 9.4 ± 6.0 and 88.5 ± 33.8 in the control groups, respectively). Changes in the P4 level were similar among the 3 groups. The E2 level of the EB group at 15 h after EB injection was significantly higher (P < 0.05) than that in the other groups (19.0 ± 15.7, 49.4 ± 22.8, and 8.0 ± 5.7 pg mL–1 in the GnRH, EB, and control groups, respectively). The number of small follicles in the control group (17.0 ± 12.2) was significantly greater (P < 0.05) than that in the GnRH group (7.4 ± 7.2) at the first AI. These results suggest that EB and GnRH injection after SOV treatment in early postpartum Japanese Black cows does not affect the SOV response or embryo quality.

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