scholarly journals Influence of the Indicators of Carbohydrate Metabolism on the Elemental Status

2021 ◽  
Author(s):  
Olga Marshinskaia ◽  
Tatiana Kazakova ◽  
Svetlana Notova ◽  
Maksim Molchanov
Keyword(s):  
Diabetes Mellitus ◽  
Trace Elements ◽  
Toxic Elements ◽  
Normal Values ◽  
Chemical Elements ◽  
Serum Parameters ◽  
Glucose Levels ◽  
Icp Ms ◽  
Elemental Status ◽  
Elevated Glucose

This study examined the elemental status of the hair and blood biochemistry of young men in the Orenburg region (n=38) with different glucose levels. Estimation of the element status was carried out through the study of the chemical composition of the hair by ICP-AES and ICP-MS. It was found that the studied serum parameters (Ca, Mg, Fe, P cholesterol, thyroxine, TSH and testosterone) were within normal values, and no statistically significant differences were obtained when comparing the groups. The concentration of chemical elements in the hair of the men in each group was in the range of physiologically acceptable values for this region. In the group with elevated glucose levels, there was a tendency for the men to have lower values of Ca and Mg, and higher levels of K, Na, P and a number of toxic elements (Al, Cd, Sn, Hg, Pb). Keywords: elemental status, trace elements, diabetes mellitus, metabolism

scholarly journals The potential of trace elements mapping in child’s natal tooth by laser ablation-ICPMS method

2021 ◽  
Author(s):  
Aneta Olszewska ◽  
Anetta Hanć
Keyword(s):  
Trace Elements ◽  
Spatial Distribution ◽  
Quantitative Assessment ◽  
Toxic Elements ◽  
Tooth Enamel ◽  
Perinatal Period ◽  
Potentially Toxic Elements ◽  
Metal Exposure ◽  
Icp Ms ◽  
Distribution Of Trace Elements

Abstract Purpose Tooth enamel might provide past chronological metabolic, nutritional status and trace metal exposure during development. Thus, the trace elements distribution embedded in tooth tissues represents an archive of the environmental conditions. The choice of biomarker is estimated as critical to the measurement of metal exposure. Natal teeth are defined as teeth being present at birth. Methods LA-ICP-MS provides a quantitative assessment of spatial distribution of trace elements in a natal tooth. The objective of the current study was to compare concentrations of building and other elements in a rare but reliable and valid biomarker - natal tooth. Results It have been reported presence of potentially toxic elements: Pb, Cu, Mn, Cd, Ni distributed in prenatally and perinatally formed enamel and dentine. Conclusions Analyses of deciduous enamel can provide answers into individuals’ earliest development, including critical pre- and perinatal period.

scholarly journals Modestly Elevated Glucose Levels During Pregnancy Are Associated With a Higher Risk of Future Diabetes Among Women Without Gestational Diabetes Mellitus

Diabetes Care ◽  
2008 ◽  
Vol 31 (5) ◽  
pp. 1037-1039 ◽  
Author(s):  
D. B. Carr ◽  
K. M. Newton ◽  
K. M. Utzschneider ◽  
J. Tong ◽  
F. Gerchman ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Glucose Levels ◽  
Elevated Glucose ◽  
Future Diabetes

scholarly journals Ecological and physiological assessment of the elemental status in the adult population of the Republic of Bashkortostan

2019 ◽  
Vol 95 (6) ◽  
pp. 533-538 ◽  
Author(s):  
A. V. Skalny ◽  
Elena S. Berezkina ◽  
V. A. Demidov ◽  
A. R. Grabeklis ◽  
M. G. Skalnaya
Keyword(s):  
Chemical Elements ◽  
Adult Population ◽  
The Body ◽  
Republic Of Bashkortostan ◽  
Icp Ms ◽  
Physiological Assessment ◽  
Elemental Status ◽  
The Russian Federation ◽  
The Republic ◽  
The Impact

The study of elemental status was carried out as a result of a multielement analysis of hair by ICP-MS within the framework of the Federal Program "National System of chemical and biological security of the Russian Federation, 2009-2014". This parameter is an index of the impact of the environment on the body. A total of 1,138 adult residents of the Republic of Bashkortostan (624 women and 514 men aged of25-50 years) were examined. The features of the element status of the adult population of the Republic were shown. The obtained data can be used as reference values of chemical elements in the hair of the adult population of the Republic of Bashkortostan.

scholarly journals Influence of the concentrations of essential and toxic elements in the blood serum on the indicators of sperm quality in Arabian purebred stallions

2022 ◽  
Vol 42 ◽  
pp. 01019
Author(s):  
V. V. Kalashnikov ◽  
A. M. Zaitsev ◽  
M. M. Atroschenko ◽  
O. A. Zavyalov ◽  
A. N. Frolov ◽  
...  
Keyword(s):  
Trace Elements ◽  
Reproductive Health ◽  
Blood Serum ◽  
Toxic Elements ◽  
Chemical Elements ◽  
Sperm Quality ◽  
Optimal Range ◽  
Essential And Toxic Elements ◽  
The Relationship ◽  
Qualitative Characteristics

Analysis of trace elements in blood serum can be an important tool for monitoring micronutrient supply in stallions in order to maintain reproductive health. In this regard, the purpose of this study was to determine the relationship between the concentrations of macro- and microelements in the blood serum of stud stallions with the qualitative characteristics of fresh sperm and sperm after cryopreservation and thawing. The studies were carried out on purebred Arabian stallions (n=50). As a biomaterial for studies, we used blood serum, fresh and thawed sperm after cryopreservation. The elemental composition of seminal plasma was determined by 25 chemical elements Co, Cr, Cu, Fe, I, Mn, Se, Zn Ca, K, Mg, P, B, Li, Si, V Na, Ni, Sn, Hg, Sr, Al, As, Cd, Pb) by ICP-DRC-MS methods. It was found that the concentrations of Mg and Co in the blood serum positively correlate with the qualitative characteristics of the sperm of Arabian purebred stallions. Wherein, the optimal range of concentrations of Mg in the blood serum, typical for stallions with relatively high indicators of sperm quality, is 22.64 to 27.05 μg/g; Co – 0.001 to 0.0015 μg/g.

Abstract 15820: Differential Myocardial Gene Expression of Glucose Transporters in Heart Transplant Recipients With and Without Diabetes Mellitus

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Marc Vanderheyden ◽  
Leen Delrue ◽  
Sofie Verstreken ◽  
Riet Dierckx ◽  
Ward Heggermont ◽  
...  
Keyword(s):  
Gene Expression ◽  
Diabetes Mellitus ◽  
Experimental Data ◽  
Heart Transplant ◽  
Glucose Transporters ◽  
Myocardial Glucose Uptake ◽  
Glucose Levels ◽  
Elevated Glucose ◽  
The Impact ◽  
Hba1c Levels

Introduction: The Sodium Glucose cotransporter (SGLT) and glucose transporters(GLUTs) play a crucial role in cellular glucose transport. Although experimental data have shown differential regulation of GLUT4 and SGLT in diabetic cardiomyopathy, the impact of diabetes mellitus (DM) upon myocardial glucose transporters in humans remains undetermined. Aim: To better understand the impact of elevated glucose levels upon myocardial expression of glucose transporters, the endomyocardial gene expression of GLUT1, GLUT4 and SGLT1 was investigated in heart transplant(HTx) recipients, with and without DM, who received a heart from a DM- donor. Methods: At baseline(BL), immediately after HTx and 12 ± 2 months(FU) later, serial endomyocardial biopsies were procured in 26 Htx pts, free of clinical or histological rejection, at time of routine surveillance biopsy. Patients were categorized in DM+ (n = 13pts) and DM- (n = 13 pts), according to the presence of diabetes mellitus (DM) at FU. Results: Despite similar hemodynamics and HbA1c levels at BL, DM+ pts had higher HbA1c levels (46,00 ± 13,79 vs 38,33 ± 4,88; p < 0,05) at FU. No differences were noted in BL GLUT1, GLUT4 and SGLT gene expression between both groups. In DM- pts SGLT1(0,081 ± 0,080 vs 0,188 ± 0,108; p = 0,0036) , GLUT4(0,076 ± 0,068 vs 0,137 ± 0,065; p = 0,0011 )and GLUT1(0,020 ± 0,021 vs 0,022 ± 0,009; p = 0,043) increased significantly at FU whereas no change was observed in DM+ pts. Conclusion: Similar to experimental data, differential endomyocardial regulation in SGLT1 and GLUT4 was noted between DM+ and DM-pts with a blunted upregulation of glucose transporters at 1 year in DM+ HTx pts. These observations are in line with experimental data and suggest that myocardial glucose uptake is differentially regulated in DM+ HTx pts.

scholarly journals Bedrock and soil geochemistry influence the content of chemical elements in wild edible mushrooms (Morchella group) from South Italy (Sicily)

2019 ◽  
Vol 54 (1) ◽  
Author(s):  
Maria Grazia Alaimo ◽  
Alessandro Saitta ◽  
Elia Ambrosio
Keyword(s):  
Trace Elements ◽  
Chemical Elements ◽  
Fungal Species ◽  
Edible Mushrooms ◽  
Soil Geochemistry ◽  
Wild Edible Mushrooms ◽  
High Concentration ◽  
Minor And Trace Elements ◽  
South Italy ◽  
Icp Ms

Chemical elements in the samples of wild edible mushrooms of the <em>Morchella</em> group collected from different unpolluted Sicilian sites was analyzed by the ICP-MS (method) to detect the content of their minerals and determine whether soil geology and geochemistry can influence the chemical composition in fungi. Results showed that the mushroom samples mainly contained a high concentration of K and P and a wide variety of minor and trace elements (V, Mo, Pb, Ce, Cs, Zr), including heavy metals. Statistical analysis showed that the mushrooms differed in their content of minor and trace elements based on the geological/geographic site of origin. Comparison with other studies showed differences in the content detected in the Sicilian morels with those collected from other geographical sites. Conversely, different fungal species collected from similar geological sites in Sicily showed different patterns of accumulation of the elements confirming that bioconcentration in fungi is species- and site-dependent.

scholarly journals ASSESSMENT OF TRACE ELEMENTS BIOAVAILABILITY – INGESTION OF TOXIC ELEMENTS FROM THE ATTIC DUST COLLECTED FROM THE VICINITY OF THE FERRO-NICKEL SMELTER PLANT

2017 ◽  
Vol 36 (2) ◽  
Author(s):  
Katerina Bačeva Andonovska ◽  
Trajče Stafilov ◽  
Irina Karadjova
Keyword(s):  
Trace Elements ◽  
Toxic Elements ◽  
Chemical Elements ◽  
Atomic Emission ◽  
High Reactivity ◽  
Emission Spectrometry ◽  
Inductively Coupled ◽  
Carbonate Buffer ◽  
Nickel Smelter ◽  
Attic Dust

The purpose of this study was to establish total and bioavailable contents of chemical elements in attic dust and their distribution in the area of the town of Kavadarci, Republic of Macedonia, and in this way to evaluate the exposure of population to toxic metals in areas with high industrial influences from the ferro-nickel smelter plant. The attic dust is derived predominantly from external sources such as aerosol deposits and soil dusting, and less from household activities. From that reason attic dust could be accepted as a tracer of historical aerosol pollution. All attic dust samples were analyzed for total and bioavailable element contents and their distribution in studied area. Several extraction agents recognized as representative for elements bioa-vailability assessment were applied to attic dust samples under investigations – phosphate buffer solutions that simulate human blood, for the simulation of lung inhalation carbonate buffer was used and 0.1 mol l–1 HCl solution to simulate stomach ingestion. A total of 18 elements (Ag, Al, As, B, Ba, Ca, Cd, Co, Cr, Cu, Fe K, Mg, Mn, Ni, Pb, Sr and Zn) were determined by atomic emission spectrometry with inductively coupled plas-ma (AES-ICP). The obtained results showed relatively high proportion of toxic elements bioavailability in the attic dusts samples from sites close to the metallurgical activities (Cr, Cu, Mn, Ni, Pb and Zn), most probably due to the small size and high reactivity of the particles of attic dust. As might be expected the highest leacha-ble amounts of toxic elements were found for Ni, Co, Cr and Pb from attic dust in the extraction solution of HCl (0.1 mol l–1 HCl) compared with the other 3 extraction media. Discussion on trace elements mobility and bioavailability related to environmental pollution and effects on human health are presented.

scholarly journals Hygienic assessment of the trace elements content in crop production in an industrially developed region

2020 ◽  
Vol 99 (9) ◽  
pp. 918-924
Author(s):  
Rustem A. Daukaev ◽  
Tatyana K. Larionova ◽  
Ahat B. Bakirov ◽  
Evgeny G. Stepanov ◽  
Anna S. Fazlieva ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Trace Elements ◽  
Chemical Composition ◽  
Crop Production ◽  
Toxic Elements ◽  
Chemical Elements ◽  
Vegetable Crops ◽  
Degree Of Contamination ◽  
Safety Control ◽  
The Republic

Introduction. Agricultural crops grown on garden plots are mainly used for personal consumption, are not subject to safety control, and therefore, the chemical composition of the produced crop products may significantly affect the accumulation or deficiency of chemical elements in the human body. Material and methods. To assess the chemical composition of the main products of plant origin produced in the regions of the Republic of Bashkortostan with different economic specialization, the content of 9 trace elements in carrots, table beets and potatoes was determined by atomic absorption spectrometry (n = 353). Using the total coefficient of anthropogenic load (Ka.n. = ∑Ci/PDUi), the territory of the Republic was ranked according to the degree of contamination of vegetable crops with toxic elements (lead, cadmium). The influence of trace elements contained in crop products on the health of the region’s population was studied using the risk assessment method. Results. Vegetables with a high content of cadmium (10.8% of the analyzed samples) occupy the largest share in the total volume of crop production that does not meet hygiene standards. When ranking the territory of the Republic on the basis of health risk assessment and the degree of contamination of vegetable crops with toxic elements, territories with a developed mining and petrochemical industry were found to be most unfavorable zones. Conclusion. The content of chemical elements in vegetable crops produced on household plots varies in a wide range, depending on the type of plant products and the place of growth. The lack of standards for the permissible content of certain trace elements in food raw materials and food products, which are priority pollutants in a number of regions, and safety control of products produced in private farms increase the risk of consumption of contaminated products by the population.

scholarly journals Additional resource for diabetes diagnostics in animals and humans

2021 ◽  
Vol 11 (40) ◽  
pp. 200-201
Author(s):  
Vladimir Vitalyevich Drozdov
Keyword(s):  
Diabetes Mellitus ◽  
Normal Values ◽  
Domestic Animals ◽  
Peganum Harmala ◽  
Study Results ◽  
Similar Disease ◽  
Elevated Glucose ◽  
Practical Development ◽  
Laboratory Variables ◽  
Latent Diabetes Mellitus

Veterinary doctors often observe cases of unexplained elevated glucose and ketones in urine of domestic animals without any other signs of diabetes. We studies these effects from the standpoint of the phenomenon of interdependent conditions in animals and humans, described by T.V.Novosadyuk in 2000. She was the first to provide a theoretical and practical foundation for clinical cases of simultaneously developing similar diseases in domestic animals and their owners. During the last 5 years we studied health of humans in families where domestic animals are affected by the laboratory abnormalities described above. In vast majority of cases it has been found out that animal owners have diabetes mellitus of variable severity. At the same time there were no disorders of carbohydrate metabolism in animal owners in 11 cases. We recommended members of these families to undergo a specialized examination. In all of these cases latent diabetes mellitus was found in humans who had especially close relationships with animals. These findings led to initiation of treatment in humans. At the same time animals were treated with a collar with a linen sack attached containing Peganum Harmala 30 globules. Repeated laboratory tests were performed after one month of such treatment. Normalization of laboratory variables was observed in all of the cases. Based on the study results we developed an algorhythm of activities that helps to diagnose early and latent forms of diabetes mellitus in domestic animals and their owners. This algorhythm includes: - test for glucose and/or ketones in animal urine after correction of feeding and care defects. - blood and urine glucose tests in family members of animal owners. In cases of deviations from normal values we recommended them to consult appropriate specialists and begin treatment immediately. - animals are given collars with Peganum Harmala 30 globules in a linen sack attached. - granules are removed when laboratory values normalize in animals. Control urinalysis is performed every three months durign a year. This approach is especially useful in latent early forms of diabetes mellitus when abnormal findings in animals or their owners enable us to suspect a similar disease in another. In such a way, the suggested algorithm is effective for organization of preclinical diagnostics in both domestic animals and their owners. In the future it is possible to enrich not only veterinary but also medical practice with new options for effective patient aid by practical development of the use of animal and human interdependent conditions.

scholarly journals Trace Element Content of Polyfloral Honey and Beeswax from the Vicinity of Non-Ferrous Metal Plant

2019 ◽  
Vol 76 (2) ◽  
pp. 125
Author(s):  
Bogdan NIKOLOV ◽  
Irena GOLUBINOVA ◽  
Plamen MARINOV-SERAFIMOV ◽  
Slaveya PETROVA
Keyword(s):  
Heavy Metals ◽  
Trace Elements ◽  
Trace Element ◽  
Toxic Elements ◽  
Ferrous Metal ◽  
Trace Element Content ◽  
Element Content ◽  
Trophic Chain ◽  
Important Place ◽  
Icp Ms

Bees and their products occupy an important place in the trophic chain “toxicant-soil-plant-bee-bee product-man”, so it has been suggested that bees and bee products should be considered as not a costly method for monitoring of the environmental pollution. Aim of the present study was to analyse trace element content of polyfloral honey and beeswax, produced in three beehives, situated in the vicinity of non-ferrous metal plant and to assess the hazardous risk at consummation. For the purposes of the study, three beehives in this area have been chosen, as follows: BH1 – located at distance of 3.8 km from the smelter, SW; BH2 – at 4 km distance, NE; BH3 – at 4.6 km distance, SE. Content of Al, Cr, Co, Cu, Fe, Mn, Ni, Pb, Sr and Zn was determined by ICP-MS. Data revealed approximately low content of heavy metals and toxic elements. Beeswax samples were found to contain significantly more Cr, Cu, Fe, Pb and Zn, in comparison with the honey samples (p<0.05). On the basis of the trace elements content in bee products, the hazardous risk at consummation could be arranged in the following descending order: BH2 > BH1 > BH3.

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