Effect of selenium supplementation on glutathione peroxidase (GPX), cholesterol, thyroxin (T4) and other blood biochemicals in local Aseel

2016 ◽  
Author(s):  
Waseem Muhammad Zia ◽  
Anjum Khalique ◽  
Saima Naveed ◽  
Jibran Hussain ◽  
Imran Muhammad
Keyword(s):  
Glutathione Peroxidase ◽  
Sodium Selenite ◽  
Control Diet ◽  
Superior Performance ◽  
Control Treatment ◽  
Control Group ◽  
Treatment Groups ◽  
Blood Biochemical ◽  
Group A ◽  
The Impact

The aim of study was to determine the impact of different selenium sources on blood biochemical picture of Aseel. Three-weeks-old 240 Aseel chickens (120 and 120) from Lakha, Mushki, Peshaweri and Mianwali varieties were randomly distributed into four groups; 60 birds/variety (30 and 30). The birds of each group of either sex were further subdivided into A, B (experimental) and C (control) treatment groups with 10 birds each. Group A and B were fed the diet containing 0.3 mg/kg Se-enriched yeast and sodium selenite, respectively, while group C was fed diet without selenium (control diet). Birds were maintained individually in cages from 4 to 21 weeks. In blood serum, glutathione peroxidase (GPx) levels increased (P£0.05) while, total cholesterol and thyroxin (T4) levels decreased (P£0.05) in Se-yeast supplemented group than sodium selenite supplemented or control group. The study concluded that Se-enriched yeast gave the superior performance to improve blood biochemical profile of Aseel.

Exploring the effect of selenium forms on final body weight, slaughtercharacteristics and tissue selenium concentration in Aseel cockerels

2016 ◽  
Author(s):  
Waseem Muhammad Zia ◽  
Anjum Khalique ◽  
Saima Naveed ◽  
Jibran Hussain ◽  
Imran Muhammad ◽  
...  
Keyword(s):  
Body Weight ◽  
Sodium Selenite ◽  
Control Diet ◽  
Selenium Concentration ◽  
Control Group ◽  
Final Body Weight ◽  
Treatment Groups ◽  
Group A ◽  
Tissue Selenium ◽  
Group B

A study to investigate the influence of selenium on final body weight and slaughter traits of Aseel was conducted. Three-weeks-old 120 cockerels from Lakha, Mushki, Peshaweri and Mianwali varieties of Aseel were randomly selected and distributed into four groups, 30 cockerels each, subdivided into 3 treatment groups A, B (experimental groups), and C (control group) with 10 cockerels in each treatment. Birds were assigned three experimental diets. The diet for the birds of group A incorporated 0.3 mg/kg Se-enriched yeast and group B included 0.3 mg/kg sodium selenite, while C was fed the diet without Se (control diet). Final body weight, dressed weight, dressing%, eviscerated weight, eviscerated%; chest, thigh and giblets weight; selenium content in chest and thigh in Se-yeast fed birds were significantly increased than those got sodium selenite or control diet. The study concluded that Se-enriched yeast is more effective in improving body weight and slaughtering characteristics of Aseel.

Studies on growth pattern of different body measurements in indigenousAseel chicken fed with selenium supplemented diets

2016 ◽  
Author(s):  
Waseem Muhammad Zia ◽  
Anjum Khalique ◽  
Saima Naveed ◽  
Jibran Hussain
Keyword(s):  
Growth Pattern ◽  
Sodium Selenite ◽  
Control Diet ◽  
Body Measurements ◽  
Treatment Groups ◽  
Group A

The experiment to test the selenium impact on body measurements of Lakha, Mushki, Peshaweri and Mianwali varieties of Aseel was conducted. A total of 240 three-weeks-aged birds were selected and divided into four groups, 60 birds per variety (30 + 30 ). These birds were subdivided into three treatment groups A, B, and C with 10 birds from each sex. Birds of group A were fed the diet supplemented with 0.3 mg/kg Se-yeast, B with 0.3 mg/kg sodium selenite and C with No selenium. Improved body measurements in the birds fed Se-yeast included diet were recorded compared to those received sodium selenite incorporated or control diet. Interaction of varieties and selenium sources presented increased breast width, keel length, wing spread, shank length, shank circumference, drumstick length and drumstick circumference in the birds of Lakha got Se-yeast supplemented diet. The study concluded that Se-yeast was more effective in enhancing body measurements of Aseel.

scholarly journals Effect of feed grade acidifiers on total tract mineral retention, intestinal pH and phytate utilization by broiler finisher chickens

2020 ◽  
Vol 44 (1) ◽  
pp. 282-289
Author(s):  
C. U. Idachaba ◽  
I. Abdullahi ◽  
D. A. Kurtong
Keyword(s):  
Broiler Chickens ◽  
Control Diet ◽  
Nutrient Utilization ◽  
Control Treatment ◽  
Control Group ◽  
Available Phosphorus ◽  
Treatment Groups ◽  
Randomized Design ◽  
Mineral Utilization ◽  
Completely Randomized Design

Mineral chelators such as organic acids have been reported to compete favourably with phytate by forming soluble complexes with feed minerals. Effect of feed grade acidifiers on total tract mineral retention and intestinal pH of broiler finisher chickens was investigated. A total of 300-broiler finisher chickens were assigned to four treatment groups. Each treatment was replicated thrice with twenty chickens per replicate in a completely randomized design. The control treatment (T1 ) was fed the control diet adequate in available phosphorus at 0.5% while other treatments (T2 -T4 ) were fed sub-optimal available phosphorus diets at 0.4%. Three blends of acidifiers; Fysal®, Orgacid® and Acidomix® were supplemented in the diets of chickens in treatments 2, 3 and 4 at 0.1% (1kg per ton/feed). Chickens fed diet supplemented  with Fysal® showed the best (P<0.05) results in total tract mineral retention 56.5+/-5.75 compared to the control and other treatments. The poor mineral retention i.e. 35 and 46% for calcium and phosphorus respectively by chickens fed the control diet was attributed to the insoluble phytate-mineral complex that limits mineral bioavailability. Intestinal segments of chickens fed acidified diets showed significant reduction (P<0.05) in pH in the range of 5.26-7.16 across duodenum to ileum compared to the control group 6.83-8.76. It is concluded that feed acidification at 0.1% improves mineral utilization in broiler chickens as it competes favourably with phytate in the lumen of the gut leading to better nutrient utilization.

Egg quality, geometry and hatching traits of indigenous Aseel as influenced by organic and inorganic selenium supplementation

2016 ◽  
Author(s):  
Waseem Muhammad Zia ◽  
Anjum Khalique ◽  
Saima Naveed ◽  
Jibran Hussain
Keyword(s):  
Sodium Selenite ◽  
Shell Thickness ◽  
Egg Quality ◽  
Shape Index ◽  
Selenium Supplementation ◽  
Egg Weight ◽  
Treatment Groups ◽  
Inorganic Selenium ◽  
Group A ◽  
The Impact

This study was conducted to evaluate the impact of selenium sources on egg and hatching traits of native Aseel chicken. Selenium-treated 21-weeks-aged 84 pullets and 12 cockerels from Lakha, Mushki, Peshaweri and Mianwali varieties (21 pullets and 3 cockerels per variety) were divided into three treatment groups A, B and C (7 pullets and 1 cockerel per group). Group A and B were experimental and C was control. Ration for group A was included 0.3 mg/kg Se-yeast, B was included 0.3 mg/kg sodium selenite and C with No selenium. Se-yeast supplementation presented increased egg weight, shell thickness, yolk index, Haugh units; enhanced egg length, breadth, volume, shape index and surface area; decreased dead germ%, dead in shell%, clear egg% and enhanced hatchability%, the hatch of fertile% and chick weight. Present study concluded that Se-yeast is a superior supplement in improving egg quality, geometry and hatching features of indigenous Aseel varieties.

scholarly journals Effects of Dietary Selenium Sources on Physiological Status of Laying Hens and Production of Selenium-Enriched Eggs

2021 ◽  
Vol 8 ◽  
Author(s):  
Kai Qiu ◽  
Jun-Jie Zheng ◽  
Uchechukwu Edna Obianwuna ◽  
Jing Wang ◽  
Hai-Jun Zhang ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Sodium Selenite ◽  
Laying Hens ◽  
Egg Quality ◽  
Control Diet ◽  
Intestinal Morphology ◽  
Control Group ◽  
Physiological Status ◽  
Treatment Groups ◽  
Organic Source

Developing new sources of organic selenium (Se) has potential benefits for animal production and human nutrition via animal-based foods enriched with Se. The objective of this study was to evaluate the effects of Se-enriched insect protein (SEIP) in comparison with other sources, such as sodium selenite (SS) and selenium-enriched yeast (SEY), on performance, egg quality, selenium concentration in eggs, serum biochemical indices, immune capacity, and intestinal morphology of laying hens. Four hundred and fifty 24-week-old Hy-Line Brown laying hens with 94.0 ± 1.5% laying rate were randomly allocated to five groups with six replicates of 15 hens each. The control diet was prepared without adding exogenous selenium (calculated basal Se content of 0.08 mg/kg). The normal group was fed basal diets supplemented with 0.3 mg/kg of Se provided by sodium selenite. Three treatment groups (SS, SEY, and SEIP, respectively) were fed basal diets supplemented with 2 mg/kg of Se provided by sodium selenite, Se-enriched yeast, and SEIP, respectively. The feeding trial lasted for 12 weeks. Results revealed that dietary supplementation of 2 mg/kg of Se increased egg weight, decreased feed conversion ratio, and enhanced the antioxidant capacity of eggs in laying hens relative to the control group, whereas no significant differences were observed among SS, SEY, and SEIP treatment groups for the same. The organic source of Se provided by SEY or SEIP showed higher bio efficiency, as indicated by higher selenium content in eggs of SEY and SEIP compared with SS, although higher content was observed in SEY compared with SEIP. Also, the organic Se source significantly improved antioxidant capacity and immune functions of laying hens than the inorganic Se source. Diets supplemented with SEIP and SS significantly improved jejunal morphology of the laying hens compared with SEY, whereas SEIP was more effective than SEY to improve the oviduct health of laying hens. The results of this work evidently points the additive effect and nontoxicity of SEIP. Thus, SEIP could be used as another organic source of Se in the diet of laying hens and production of selenium-enriched eggs for humans.

Mechanism Involved in Fortification by Berberine in CDDP-Induced Nephrotoxicity

2020 ◽  
Vol 13 (4) ◽  
pp. 342-352 ◽  
Author(s):  
Vipin K. Verma ◽  
Salma Malik ◽  
Ekta Mutneja ◽  
Anil K. Sahu ◽  
Kumari Rupashi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Renal Tissue ◽  
Isoquinoline Alkaloid ◽  
Experimental Models ◽  
Beclin 1 ◽  
Control Treatment ◽  
Control Group ◽  
Treatment Groups ◽  
Single Intraperitoneal Injection ◽  
Male Wistar Rats

Background: The activation of Nrf2/HO-1 pathway has been shown to protect against cisplatin- induced nephrotoxicity by reducing oxidative stress. Berberine (Ber), an isoquinoline alkaloid, has demonstrated antioxidant, anti-inflammatory and anti-apoptotic activities in various experimental models. Aim: To check the effect of Ber on cisplatin-induced nephrotoxicity and to explore the involved mechanism. Methods: Adult male Wistar rats were divided into 6 groups: Normal, cisplatin-control, treatment groups and per se group. Normal saline and Ber (20, 40 and 80 mg/kg; p.o.) was administered to rats for 10 days. A single intraperitoneal injection of cisplatin (8 mg/kg) was injected on 7th day to induced nephrotoxicity. On 10th day, rats were sacrificed, the kidney was removed and stored for the estimation of various parameters. Results: As compared to cisplatin-control group, Ber pretreatment improved renal function system and preserved renal architecture. It also diminished oxidative stress by upregulating the expression of Nrf2/HO-1 proteins. In addition, Ber attenuated the cisplatin mediated inflammation and apoptosis. Furthermore, it also reduced the phosphorylation of p38/JNK and PARP/Beclin-1 expression in the kidney. Conclusion: Ber attenuated renal injury by activating Nrf2/HO-1 and inhibiting JNK/p38MAPKs/ PARP/Beclin-1 expression which prevented oxidative stress, inflammation, apoptosis and autophagy in renal tissue.

Glycine and L-Arginine supplementation ameliorates gastro-duodenal toxicity in a rat model of NSAID (Diclofenac)-gastroenteropathy via inhibition of oxidative stress

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Akinleye Stephen Akinrinde ◽  
Halimot Olawalarami Hameed
Keyword(s):  
Oxidative Stress ◽  
Total Protein ◽  
Therapeutic Index ◽  
Control Treatment ◽  
Control Group ◽  
Protective Effects ◽  
Serum Total Protein ◽  
Significant Amelioration ◽  
Group A ◽  
Group B

Abstract Objectives This study examined the possible protective roles of exogenous glycine (Gly) and L-Arginine (l-Arg) against Diclofenac (DIC)-induced gastro-duodenal damage in rats. Methods Rats were divided into Group A (control), Group B (DIC group) and Groups C–F which were pre-treated for five days with Gly1 (250 mg/kg), Gly2 (500 mg/kg), l-Arg1 (200 mg/kg) and l-Arg2 (400 mg/kg), respectively, before co-treatment with DIC for another three days. Hematological, biochemical and histopathological analyses were then carried out. Results DIC produced significant (p<0.05) reduction in PCV (13.82%), Hb (46.58%), RBC (30.53%), serum total protein (32.72%), albumin (28.44%) and globulin (38.01%) along with significant (p<0.05) elevation of serum MPO activity (83.30%), when compared with control. In addition, DIC increased gastric H2O2 and MDA levels by 33.93 and 48.59%, respectively, while the duodenal levels of the same parameters increased by 19.43 and 85.56%, respectively. Moreover, SOD, GPx and GST activities in the DIC group were significantly (p<0.05) reduced in the stomach (21.12, 24.35 and 51.28%, respectively) and duodenum (30.59, 16.35 and 37.90%, respectively), compared to control. Treatment with Gly and l-Arg resulted in significant amelioration of the DIC-induced alterations although l-Arg produced better amelioration of RBC (29.78%), total protein (10.12%), albumin (9.93%) and MPO (65.01%), compared to the DIC group. The protective effects of both amino acids against oxidative stress parameters and histological lesions were largely similar. Conclusions The data from this study suggest that Gly or l-Arg prevented DIC-induced gastro-duodenal toxicity and might, therefore be useful in improving the therapeutic index of DIC.

scholarly journals Effects of a Trans-Galactooligosaccharide on Minerals Content of Common Carp (Cyprinus carpio L.) Tissues

2021 ◽  
Author(s):  
Ewa Ziółkowska ◽  
Joanna Bogucka ◽  
Jan Mazurkiewicz ◽  
Mateusz Rawski ◽  
Szymon Różański ◽  
...  
Keyword(s):  
Common Carp ◽  
Cyprinus Carpio ◽  
Control Diet ◽  
Colorimetric Method ◽  
Bifidobacterium Bifidum ◽  
Feed Additives ◽  
Control Treatment ◽  
Control Group ◽  
Whole Cells ◽  
Freeze Dried

AbstractCommon carp (Cyprinus carpio L.) is a dominant fish species in aquaculture, and as it is a stomachless species, absorption and digestion of nutrients take place in the intestine. The aim of the study was to evaluate the effects of a prebiotic on the content of selected minerals found in the meat, gills, and skeleton of common carp. The research applied trans-galactooligosaccharide (GOS) prebiotic produced by enzymatic transgalactosylation of milk lactose by whole cells of Bifidobacterium bifidum. The following diets have been applied: control diet without feed additives (C), diet 2 (B1) with 1% of GOS, and diet 3 (B2) with 2% of GOS. In the freeze-dried samples, concentrations of the analyzed metals were determined using atomic absorption spectroscopy (AAS). The content of phosphorus was determined using colorimetric method. The analyses confirmed that the highest level of Mg was detected in the skeleton of fish fed with 1% GOS (2.51 g kg−1) and was significantly higher compared the control treatment (2.11 g kg−1) (P < 0.05). Zn content in fish meat fed with 1% GOS (35.41 mg kg−1) was significantly higher (P < 0.05) than in the control group (24.59 mg kg−1). The tissue that accumulated the greatest amount of Zn was the gills. GOS had a positive effect on Fe accumulation in the meat, gills, and skeleton. It has been concluded that supplementation of feed with 2% GOS significantly influenced the positive correlations between Mg and P in the meat and skeleton, Fe–Ca correlation in gills, and Fe–Zn correlation in the skeleton.

scholarly journals The Influence of the Physiotherapeutic Program on Selected Static and Dynamic Foot Indicators and the Balance of Elderly Women Depending on the Ground Stability

2021 ◽  
Vol 18 (9) ◽  
pp. 4660
Author(s):  
Joanna Matla ◽  
Katarzyna Filar-Mierzwa ◽  
Anna Ścisłowska-Czarnecka ◽  
Agnieszka Jankowicz-Szymańska ◽  
Aneta Bac
Keyword(s):  
Elderly Women ◽  
Statistical Significance ◽  
Exercise Program ◽  
Control Group ◽  
Balance Assessment ◽  
Motor Functions ◽  
Static Test ◽  
Group A ◽  
Group B ◽  
The Impact

Seniors are a constantly growing group of people in many societies. It is necessary to develop physiotherapeutic programs to improve their mobility. The aim of this study was to assess the impact of the physiotherapeutic program conducted unstable ground on selected indicators of motor functions of elderly women. Sixty women (60–80 years) participated in the research. Group A (N = 20) underwent a 12-week physiotherapeutic program on stable ground, group B (N = 20) followed an exercise program on unstable ground, and group C (N = 20) (control group) had no therapeutic intervention. The effects of the therapy were assessed by using a FreeMed platform (foot load analysis) and a Biosway balance system. The results were compared using ANOVA (the one-way analysis), the Kruskal–Wallis test and also the post hoc tests (Tukey’s test and the multiple comparison test). In group A, a statistically significant change was observed in the static test and balance assessment, in group B this was observed in the static and dynamic foot tests and balance assessment, in group C, no statistical significance was achieved. The authors’ physiotherapeutic program had a statistically significant effect on changes in the balance and selected indicators of the motor functions of the examined people. Comparing the results before and after the therapy more improvement changes were noted in women training on an unstable ground compared to women training on a stable ground.

scholarly journals Effects of Different Dietary Levels of Whey Lactose as a Prebiotic Disaccharide on the Productive Performances and Selected Indices of the Caecal Micro-Environment in Broiler Chickens

2017 ◽  
Vol 17 (4) ◽  
pp. 1107-1122 ◽  
Author(s):  
Mohamed Nabil Alloui ◽  
Witold Szczurek
Keyword(s):  
Broiler Chickens ◽  
Volatile Fatty Acids ◽  
Body Weight Gain ◽  
Control Diet ◽  
Coliform Bacteria ◽  
Control Group ◽  
Breast Meat ◽  
Plate Counts ◽  
Acid Producing Bacteria ◽  
The Impact

AbstractThe primary aim of this study was to investigate the impact of three dietary levels of lactose (LAC) originating from conventional dried whey (DW) and the duration of these treatments (from 8 to 21 or to 42 days of age) on growth performance, basic post-slaughter traits and excreta quality of broiler chickens kept in cages. A secondary purpose was to investigate the effect of LAC level on some parameters of the caecal micro-environment and gross morphology in these birds. A total of 560 Ross 308 chickens (sex ratio 1:1) were assigned to 7 dietary combinations with 10 replicate cages of 8 birds per cage. The control group was fed basal diets consisting of maize, wheat and soybean meal. The other 6 groups received the same basal diets with DW added in amounts equivalent to a LAC dietary levels of 1, 2 or 3%. Only continuous feeding (day 8 to 42) with 1% and 2% levels of LAC was found to yield the overall body weight gain (BWG) during the whole 42-day rearing period, which was significantly higher than that on the control diet, with a larger share of breast meat in carcass at a 2% LAC. However, these effects were associated with greater faecal score values indicating more watery excreta compared with the control. Increasing levels of LAC augmented the relative caecal weight and length. A reduction in the caecal pH was confirmed at day 21 for birds fed 1% and 2% of dietary LAC. The lower pH values were correlated to an increased sum of total volatile fatty acids (VFA), causing large increases in the concentration of undissociated forms of individual VFA. The decline in plate counts of coliform bacteria was observed with 2% and 3% LAC, whereas the counts of lactic acid-producing bacteria (LAB) were higher at these two LAC levels. The present findings lead to the conclusion that the dietary level of 2% LAC originated from DW is the most effective in enhancing the productivity of broilers, with moderate occurrence of undesirable side effects.

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