scholarly journals Association of age at menarche, parity, and hormonal contraceptive use with the histologic type of ovarian cancer

2021 ◽  
Vol 29 (3) ◽  
pp. 118
Author(s):  
Firda Azizah ◽  
Pungky Mulawardhana ◽  
Willy Sandhika

HIGHLIGHT1. Relationship between age at menarche, parity, and contraceptive use with histologic type of ovarian cancer was analyzed. 2. A number of patients with ovarian cancer were analytically observed with retrospective cross-sectional approach and the histologic types of the cancer were determined.3. Age of menarche, parity, and hormonal contraceptive use was found not to have significant correlation with histologic type of ovarian cancer. ABSTRACTObjectives: This study analyze the relationship between age at menarche, parity, and contraceptive use with histologic type of ovarian cancer.Materials and Methods: This study used an observational analytic with a retrospective cross-sectional approach. The research samples were 128 patients with ovarian cancer at RSUD Dr. Saiful Anwar Malang in 2017-2019, all patients underwent primary staging laparotomy. The histologic type of ovarian cancer consist of: serous 45, mucinous 45, endometrioid 10, clear cell 20, and others 4. Data analysis using chi square.Results: The p value for the relationship between the age of menarche and histologic type of ovarian cancer was p = 0.500 (p> 0.05), parity p = 0.313, and contraceptive use p = 0.824. The distribution of clear cell was more common in multiparous, 40% of endometrioid found in nulliparous, serous were more common in women with hormonal contraceptive use >5 years, whereas mucinous were more common in history of use <5 years.Conclusion: There was no significant relationship between the age of menarche, parity, and hormonal contraceptive use on  histologic type of ovarian cancer.

Author(s):  
Rahmi Fitria

Menarche is a sign of the proper functioning of a woman's reproductive organs when having her first menstruation and is common in the age range of 10-16 years. Menarche is influenced by several factors, one of which is nutritional status. According to Noviyanti research (2016) nutrition affects a girl's sexual maturity so that it affects the slowness of menarche. Similarly, research conducted by Munda (2016) that students with overweight nutritional status faster experienced menarche compared to students who have normal nutritional status and underweight. This study aims to find out the relationship of nutritional status to the age of menarche grade VII students in Pesantren Bahrul Ulum. This research method uses descriptive method with cross sectional research design. This research was conducted in SDN 007 Rambah. The sample of this study amounted to 45 respondents. Data collection uses simple correlation and linear regression tests. The results of this study stated that the average nutritional status of grade VII students is 21.60Kg /m2, and the nutritional status of students is at least 16.90 Kg / m2 and the highest nutritional status is 27.60 Kg / m2 with an average age of menarche 12.11 years. The conclusion of this study is that there is no relationship of nutritional status with menarche age in grade VII students in Pesantren Bahrul Ulum with a value of p= 0.036.


2021 ◽  
Vol 2 (1) ◽  
pp. 23-28
Author(s):  
Alexander Petra Sihite ◽  
I Gusti Ngurah Pramesemara ◽  
I Wayan Surudarma

Background: Type 2 diabetes mellitus is a metabolic disease that characterized by high blood sugar levels. This condition is often not noticed immediately and usually patient starting to realize it when complications have been occurred. A long-term complication of type 2 DM that occurred in men is erectile dysfunction (ED). ED is a condition when a person is unable to achieve or maintain an erection for sexual intercourse. One factor that influence the occurrence of ED and its severity in type 2 DM patients is the duration of the disease. Objective: The aim of this study was to determine the relationship of type 2 DM duration and the occurrence of ED. Methods: This study is an observational analytic cross-sectional study conducted at the Puskesmas (Public Health Center) Denpasar Barat I. The research data was obtained through medical record data and fill the International Index of Erectile Function (IIEF-5) questionnaire on 36 type 2 DM patients aged around 40-60 years. The statistical analysis used was Fisher's exact test. Results: The results showed that of the 36 samples, 19 (52.8%) samples had type 2 DM <24 months and 17 (47.2%) samples had type 2 DM >24 months. It was found that 5 (13.9%) samples did not experience ED while the rest experienced ED with different severity. There was a significant relationship between the type 2 DM duration and the occurrence of erectile dysfunction at Puskesmas Denpasar Barat I (p = 0.022). Conclusion: Study has found that type 2 DM patients with the longer duration (>24 months)  have a higher occurrence of ED and tended to be more severe compared to those with shorter duration (<24 months). Further studies should be performed with higher number of patients and more controlled risk factor so it will be more accurate in determining the relationship between the duration of type 2 DM and ED.


2021 ◽  
Author(s):  
Nurul Asikin

The onset of menarche is part of physical and sexual maturity process. Previous studies have shown that the nutritional status of an adolescenst girl have important influence on the menarche age. The study was designed to determine the age of menarche and its relation to nutritional status of adolescent girls in SMP Negeri 10 Bulukumba. This was an analytical survey with a Cross Sectional Study approach. The sample in this study consisted of 74 people (total sampling), namely all students who had experienced menarche. The result of this study indicate that of the 74 respondents studied, there were 48 respondents had a good nutritional status, 43.75% had experienced normal menarche and 56.25% had experienced abnormal menarche. There were 26 respondents had a malnutrition, 15.38% had experienced normal menarche and 84.62% had experienced abnormal menarche. The results of statistical tests showed that there was an association between the nutritional status and the age at menarche of adolescent girls in SMP Negeri 10 Bulukumba (Pv=0,020; OR= 4,28). It is concluded that nutritional status is significantly associated with the age at menarche in adolesence. A good nutritional status in adolescent girls will experience puberty normally, resulting in normal and uninterrupted menstruation.


Neurology ◽  
2017 ◽  
Vol 89 (6) ◽  
pp. 563-569 ◽  
Author(s):  
Annette Langer-Gould ◽  
Jessica B. Smith ◽  
Kerstin Hellwig ◽  
Edlin Gonzales ◽  
Samantha Haraszti ◽  
...  

Objective:To determine whether women who breastfeed their infants longer or have fewer ovulatory years are at lower risk of developing multiple sclerosis (MS).Methods:We recruited women with newly diagnosed MS or its precursor, clinically isolated syndrome (CIS) (n = 397), and matched controls (n = 433) into the MS Sunshine Study from the membership of Kaiser Permanente Southern California. A structured in-person questionnaire was administered to collect the behavioral (pregnancies, breastfeeding, hormonal contraceptive use) and biological (age at menarche and menopause, amenorrhea) factors to make up ovulatory years.Results:Among women who had live births, a cumulative duration of breastfeeding for ≥15 months was associated with a reduced risk of MS/CIS (adjusted odds ratio [OR] 0.47, 95% confidence interval [CI] 0.28–0.77; p = 0.003 compared to 0–4 months of breastfeeding). Being ≥15 years of age at menarche was also associated with a lower risk of MS/CIS (adjusted OR 0.56, 95% CI 0.33–0.96; p = 0.035). Total ovulatory years and the remaining factors that determine it, including gravidity, parity, episodes of amenorrhea, and hormonal contraceptive use, as well as age at first birth, showed no significant association with the risk of MS/CIS.Conclusions:Mothers who breastfeed longer may be at lower subsequent risk of developing multiple sclerosis. This is consistent with the other known maternal health benefits of breastfeeding and with our previous observation that women with MS who breastfeed exclusively are at lower risk of postpartum relapses.


Author(s):  
Noor Dharmarha ◽  
Anuradha Konda

Background: Present study highlights that the worldwide trend of declining age at menarche is also seen in urban Indian girls. The aim of the study was to evaluate the age of menarche and to find out the factors associated with the timing of menarche.Methods: The study was an observational cross sectional study. 258 healthy, menstruating, adolescent girls aged 10-16 years, were selected by simple random sampling. Pre-designed structured questionnaires were distributed after taking informed consent. Anthropometric measurements were taken using standard techniques. The average age of menarche was calculated. The association of the age at menarche with the proposed factors was analyzed using chi square test and Pearson’s correlation coefficient. “P value” less than 0.05 was considered as significant.Results: The mean age at menarche was found to be 12.23±1.09 years. The study found a strong association between the respondent’s age at menarche and her sister’s age at menarche (p=0.002). The study also found a strong association between age at menarche and the socioeconomic status (p=0.021). This study however found no association of menarcheal age with factors like birth weight, type of diet, frequency of milk intake, body mass index, waist hip ratio, amount of exercise, unstable environment at home and psychosocial stress.Conclusions: The worldwide trend of declining age at menarche is also seen in urban Indian girls. This trend underlines the importance of investigating the factors associated with it and studying the future implications of a lower age at menarche.


Author(s):  
Rakhee Ambade ◽  
Mohan Sagdeo

Background: Population studies on characteristics of menstrual cycles are scarce. Knowledge on this variability is necessary for patient education and to guide clinical evaluation.Methods: A cross sectional study was conducted and 622 school girls were selected randomly. A pretested questionnaire was used to gather data.Results: Mean age of participants was 16.9 ± 1 years. About 92.2% had attained menarche. Probit analysis of the status-quo data yielded median age at menarche of 14.8 (13.9-15.3) years and by recall method to be 15.8 ± 1 years. The mean age at menarche was, significantly, 0.3 years younger for urban females compared with rural ones. Cycle length between 21-35 days was observed in 70.3% of the girls. Mean duration of flow was 4 ± 1.3 days. Menstrual cycles were irregular in 42.8% of the subjects. Overall prevalence of dysmenorrhoea was 72%. and of PMS was 75.4%.Conclusions: Age of menarche was found to be significantly delayed. Considerable number of students complained of dysmenorrhoea and premenstrual symptoms.


2021 ◽  
Vol 1 (2) ◽  
pp. 19-25
Author(s):  
Khadijah Banjar ◽  
Sharafaldeen Bin Nafisah

Background Patient satisfaction with an ED visit is often overlooked during the ongoing COVID-19 pandemic, and requires further examination. Aim We aim to investigate, on a national scale, patients’ satisfaction during their ED encounter, and to explore the determinants of such satisfaction. Methods This is a cross-sectional analysis conducted between January and February 2021 throughout Saudi Arabia. Result The total number of patients was 508. The median satisfaction score for the clarity of information provided in the ED was 40 (SD=4.94), while satisfaction with the relationship with staff and ED routine revealed a median score of 39.9 (SD=5.08). We noted several determinants of ED satisfaction, including age, marital status, educational status, clarity of the treatment plan, improvement of their condition while in the ED, verbal and/or written discharge instructions, as well as a follow-up call two days after discharge. Conclusion Patient satisfaction is an integral part of the patient-centred approach in the ED, and should be continuously evaluated.  


2020 ◽  
Vol 10 (2) ◽  
pp. 101-110
Author(s):  
Yusri Kartika ◽  
Sudarto Ronoatmodjo

Abstract Background: Prevalence of obesity in adult females in Indonesia is 32,9% in 2013. Hormonal contraceptives (pills, injections and implants) are widely used by reproductive-age women in Indonesia, and the prevalence is 45%. Objective: The aim of this study is to identify whether reproductive-age women who use hormonal contraceptives are at risk of developing obesity compared to WUS who do not use hormonal contraceptives. Method: The design of this study is a cross sectional study using secondary data (5th Indonesia Family Life Survey, and the sample is reproductive-age women (15-49 years old) consisting of 6045 respondents. The variables of this study are obesity, hormonal contraceptive use, age, education, occupation, and duration of contraceptive use. Data were analysed by using Cox Regression. Result: The results of bivariate analysis showed that hormonal contaceptive use, age, education, occupation, and duration of contraceptive use were associated with obesity among reproductive-age womenand statistically significant (P-Value <0,05). Multivariate analysis showed that hormonal contraceptive use did not increase the risk of obesity among reproductive-age women in Indonesia (PR 0.939; CI 95% 0.869 - 1.013). Conclusion: The use of hormonal contraception did not increase the risk of obesity among reproductive-age women. Key words: Hormonal Contraception; Obesity; Reproductive Age-Women Abstrak Latar belakang : Prevalensi obesitas pada perempuan dewasa di Indonesia sebesar 32,9 persen pada tahun 2013. Kontrasepsi hormonal (pil, suntikan dan implan) merupakan jenis kontrasepsi yang paling banyak digunakan oleh wanita usia subur (WUS) di Indonesia, dengan prevalensi sebesar 45%. Tujuan : untuk mengetahui apakah wanita usia subur (WUS) yang menggunakan kontrasepsi hormonal berisiko mengalami obesitas dibandingkan WUS yang tidak menggunakan kontrasepsi hormonal.  Metode : Desain penelitian ini adalah studi cross- sectional dengan menggunakan data sekunder IFLS 5 tahun 2014. Sampel adalah WUS (15-49 tahun) sebanyak 6.045 responden. Variabel dalam penilitian ini adalah obesitas pada WUS, penggunaan kontrasepsi hormonal, umur, pendidikan, pekerjaan, serta lama penggunaan kontrasepsi. Analisis data yang digunakan adalah Cox Regression. Hasil : Hasil analisis bivariat menunjukkan bahwa variabel penggunaan kontrasepsi hormonal, umur, pendidikan dan status pekerjaan, serta  lama penggunaan kontrasepsi berhubungan dengan obesitas pada WUS (p-value <0,05). Analisis multivariat menunjukkan bahwa penggunaan kontrasepsi hormonal tidak meningkatkan risiko obesitas secara bermakna pada WUS di Indonesia (PR 0,939; CI 95% 0,869 – 1,013). Kesimpulan: Penggunaan kontrasepsi hormonal tidak meningkatkan risiko WUS untuk mengalami obesitas.   Kata kunci: Kontrasepsi Hormonal; Obesitas; Wanita Usia Subur


2021 ◽  
Vol 14 (1) ◽  
pp. 63-67
Author(s):  
Nur Zuwariah ◽  
Rizki Amalia ◽  
Syafaatul Ainiyah

One of the most dangerous diseases for Indonesian women is cervical cancer. Hormonal contraceptive use is one of the risk factors for cervical cancer, especially in prolonged use for more than five years. This study evaluates the correlation between hormonal contraceptive use with cervical cancer incidence in Surabaya Wisnuwardhana Cancer Foundation. In this research, the authors used the analytical design with the cross-sectional approach. There were 30 respondents selected with the purposive sampling technique. The independent variable was hormonal contraceptive use, and the dependent variable was cervical cancer incidence. The instruments utilized questionnaires and medical records. Data analysis applied the Rank-spearman test with the significance level of α = 0.05. The results showed that most of the respondents (63,3%) used hormonal contraception. Almost half of them (46.7%) are categorized in class 2 of pap smear classification (mild infection). Hormonal contraceptive use correlated with cervical cancer incidence (p=0.005). The prolonged hormonal contraceptive use, the greater cervical cancer incidence in women.  


2020 ◽  
Vol 11 (2) ◽  
pp. 155-165
Author(s):  
Magdalena Agu Yosali ◽  
Nurlita Bintari

Breast cancer is a cancer that occurs most often among women, which affects the 1,5 million women every year and cause the death toll due to cancer is found among women.In 2015, 570.000 women dying of breast cancer, which is about 15 % of cancer death among women.The incident breast cancer relating to the risk of breast cancer, the main risk factors associated with the incident breast cancer is the state of hormonal and genetic. Family history hormonal factors can be influenced by some one is the age of menarche To know relations age menarche with the occurrence of breast cancer in women age 25-55 years in women in Yayasan Kanker Payudara Indonesia ( YKPI ) in 2019. This is the kind of research quantitative research with a design research analytic used the cross sectional performed at Yayasan Kanker Payudara Indonesia (YKPI) Jakarta in 2019 , respondents were 30 .Uses the technique total sampling .An instrument used is the questionnaire and a observation and analysis techniques using spearman.The results of the analysis of 30 the smallest number of respondents there are 22 ( 100 % ) a woman whose period menarche at the age of ≤ 12 years the proportion who experienced breast cancer , from 30 the smallest number of respondents there are 20 ( 100 % ) a woman whose period menarche ≤ 12 year have been of breast cancer 8 ( 80 % ) a woman whose period menarche > 12 year have been of breast cancer , 2 ( 20% ) a woman whose period menarche & gt; 12 years they had experienced no cancer of the breast , sehigga ho refused to play host to which would mean there are even closer ties between the between the ages of menarche with an instance of cancer of the breast . P value = 0,007 .The value of persons of very = 0,800 As for advice for the research can be used as evalusi in providing information about breast cancer.


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