scholarly journals ANTIBACTERIAL EFFECT OF MAULI BANANA STEM EXTRACT, BASIL LEAF EXTRACT, AND THEIR COMBINATION ON Staphylococcus aureus

2020 ◽  
Vol 5 (2) ◽  
pp. 153
Author(s):  
Almadina Latanza ◽  
Maharani Laillyza Apriasari ◽  
Yusrinie Wasiaturrahmah
Keyword(s):  
Staphylococcus Aureus ◽  
Leaf Extract ◽  
Povidone Iodine ◽  
Antibacterial Effect ◽  
Inhibition Zone ◽  
Diffusion Method ◽  
Group Vi ◽  
Group I ◽  
Stem Extract ◽  
Banana Stem

ABSTRACTIntroduction: Mauli banana stem and basil leaf extracts have an antibacterial effect on Staphylococcus aureus because they contain flavonoid, saponin, alkaloid, tannin, and eugenol. 1% povidone iodine is commonly used as an antiseptic and gargle for recurrent aphthous stomatitis caused by Staphylococcus aureus. Prolonged use of 1% povidone iodine is notable to possess adverse effects. Objective: To prove the antibacterial effect of mauli banana stem extract with 25% concentration, basil leaf extract with 12.5% concentration, and mauli banana stem and basil leaf combination extract with 25%, 50%, and 75% concentration on Staphylococcus aureus and compared to 1% povidone iodine. Methods: This study was applying the true experimental design with post-test only and control group design which consisted of 6 treatments. Group I was given with Mauli banana stem extract with 25% concentration, group II with basil leaf extract with 12.5% concentration, group III, IV, and IV with mauli banana stem and basil leaf combination extract with 25%, 50%, and 70% concentration, respectively. Meanwhile, group VI was given with 1% povidone iodine as a positive control. Each treatment had 4 times repetition. Antibacterial effectivity was assessed from the inhibition zone measurement of Staphylococcus aureus growth using the diffusion method. Results: This study revealed that the mean inhibition zone formed in group I was 6-6.2 mm, group II was 6-6.2 mm, group III was 6-6.9 mm, group IV was 7.6-8 mm, group V was 8-8.5 mm, and group VI was 10.6-11.8 mm. Conclusion: The antibacterial efficacy of mauli banana stem extract at 25% concentration, basil leaf extract at 12.5% concentration, mauli banana and basil leaf combination extract at 25%, 50%, and 75% concentration on Staphylococcus aureus has been proven but not equal to 1% povidone iodine’s efficacy. Keywords: Basil leaf extract, Diffusion method, Inhibition zone, Mauli banana stem extract, Staphylococcus aureus,.

scholarly journals ANTIFUNGAL EFFECT OF MAULI BANANA STEM EXTRACT, BASIL LEAF EXTRACT, AND THEIR COMBINATION ON Candida albicans

2020 ◽  
Vol 5 (2) ◽  
pp. 179
Author(s):  
Hadi Waskito ◽  
Maharani Laillyza Apriasari ◽  
Juliyatin Putri Utami
Keyword(s):  
Candida Albicans ◽  
Leaf Extract ◽  
Oral Candidiasis ◽  
Inhibition Zone ◽  
Chlorhexidine Gluconate ◽  
Diffusion Method ◽  
Antifungal Effect ◽  
Group I ◽  
Stem Extract ◽  
Banana Stem

ABSTRACTBackgrounds: Oral candidiasis is an oral infection caused by abnormal growth of Candida albicans. The use of 0.2% chlorhexidine gluconate as a prophylactic mouthwash is conducted for oral candidiasis therapy. Prolonged use of 0.2% chlorhexidine gluconate is recorded to instigate side effects. Mauli banana stem extract and basil leaf extract demonstrate antifungal properties ascribed to their contents. Objective: To prove that the antifungal effect of 25% concentration of mauli banana stem extract, 12.5% concentration of basil leaf extract, and 25%, 50%, and 75% concentration of mauli banana stem and basil leaf combination extract on Candida albicans are comparable to 0.2% chlorhexidine gluconate. Methods: This study was resolved by applying the true experimental design with post-test only and control group design which consisted of 6 treatments. Group I was given Mauli banana stem extract with 25% concentration, group II was given basil leaf extract with 12.5% concentration, group III, IV, and IV were given the combination of Mauli banana stem and basil leaf extracts with 25%, 50%, and 75% concentrations, respectively. Meanwhile, group VI was given 1% chlorhexidine gluconate as a positive control. Each treatment was served with four times repetition. Antibacterial effectivity was assessed through the inhibition zone measurement of 0.2% chlorhexidine gluconate growth using the diffusion method. Results: This study revealed that the average diameter of inhibition zone formed in group I was 6-6.3 mm, group II was 6-6.2 mm, group III was 6-6.2 mm, group IV was 7-7.2 mm, group V was 10.2-11.4 mm, and group VI was 23.7-24.8 mm. Conclusion: The antifungal effect of mauli banana stem extract at 25% concentration, basil leaf extract at 12.5% concentration, and mauli banana stem and basil leaf combination extract at 25%, 50%, and 75% concentration on Candida albicans has been proven but not equivalent to 0.2% chlorhexidine gluconate.Keywords: Basil leaf extract, Candida albicans,inhibition zone, 0.2% chlorhexidine gluconate, diffusion method, Mauli banana stem extract,.

scholarly journals Fitokimia Dan Aktivitas Antibakteri Dari Daun KAF(Chisocheton sp. (C. DC) HARMS)

Jurnal MIPA ◽  
2019 ◽  
Vol 8 (2) ◽  
pp. 42
Author(s):  
Florentin Natalia Melsadalam ◽  
Dewa Gede Katja ◽  
Meiske S. Sangi
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Secondary Metabolites ◽  
Ethyl Acetate ◽  
Leaf Extract ◽  
Inhibition Zone ◽  
Diffusion Method ◽  
Inhibitory Zone ◽  
Escherichia Coli Bacteria

Telah dilakukan penelitian yang bertujuan untuk mengidentifikasi senyawa metabolit sekunder  dari ekstrak daun kaf menggunakan tiga jenis pelarut yakni n-heksan, etil asetat, dan metanol. Ekstrak yang diperoleh diuji aktivitas antibakterinya dengan metode difusi yang menggunakan bakteri Staphylococcusaureus dan Escherichia coli. Dari hasil pengujian fitokimia, ketiga ekstrak tersebut menunjukan bahwa sampel mengandung senyawa; alkaloid, saponin, steroid, flavonoid dan tanin. Pengujian aktivitas antibakteri  dengan metode difusi menunjukan hasil yang paling tinggi aktivitas antibakteri adalah  estrak etil asetat dengan zona hambat 35,75 mm terhadap bakteri  Staphylococcus aureus, sedangkan pada ekstrak metanol memiliki zona hambat 23,75 mm terhadap bakteri Escherichia coliResearch has been carried out aimed at identifying secondary metabolites of kaf leaf extract using three types of solvents, namely n-hexane, ethyl acetate, and methanol.The obtained extracts were tested for antibacterial activity by diffusion method using Staphylococcus aureus and Escherichia coli bacteria. From the results of phytochemical testing, the three extracts showed that the sample contained compounds; alkaloids, saponins, steroids, flavonoids and tannins. Antibacterial activity testing with diffusion method showed the highest antibacterial activity was estracethyl ethyl acetate with 35.75 mm inhibition zone against Staphylococcus aureus bacteria, whereas methanol had 23.75 mm inhibitory zone against Escherichia coli bacteria

scholarly journals Uji efek antibakteri ekstrak batang akar kuning (Arcangelisia flava Merr.) terhadap bakteri Staphylococcus aureus dan Escherichia coli

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Angga Dehes Kaharap ◽  
Christy Mambo ◽  
Edward Nangoy
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Effect ◽  
Average Diameter ◽  
Inhibition Zone ◽  
Diffusion Method ◽  
Bark Extract ◽  
Root Extract ◽  
Root Bark ◽  
Modified Technique

Abstract: Indonesia has a high diversity of flora and fauna in the world. Many types of plants can be used as a medicinal plant; one of them is yellow root (Arcengelisia flava Merr.) which has been known empirically by the Dayak community in Central Kalimantan as natural herbs to treat jaundice. This study aimed to determine the antibacterial effect of the yellow root bark extract against Staphylococcus aureus and Escherichia coli. This study was conducted in the Laboratory of Pharmacology and the Laboratory of Microbiology Faculty of Medicine University of Sam Ratulangi. This was an experimental laboratory study using the Kirby-Bauer modified technique. Yellow root bark extract was obtained from maceration process using ethanol 96%. The antibacterial effect was tested by using the well diffusion method. The results showed that distilled water, the negative control, did not generate inhibition zone around the wells. Ciprofloxacin, the positive control, had the greatest diameter of inhibitory zone. The average diameter of inhibition zone generated by ciprofloxacin was 39.23 mm against Staphylococcus aureus and 40.95 mm against Escherichia coli. Meanwhile, yellow root extract generated an average diameter inhibition zone of 12.27 mm against Staphylococcus aureus and 14.44 mm against Escherichia coli. Conclusion: Yellow root bark extract potentially had antibacterial effect against Staphylococcus aureus and Escherichia coli. Keywords: antibacterial, yellow root bark, Staphylococcus aureus, Escherichia coli. Abstrak: Indonesia memiliki keberagaman flora dan fauna yang tinggi di dunia. Banyak jenis tanaman yang dapat dijadikan sebagai tanaman obat, salah satunya akar kuning (Arcangelisia flava Merr.) yang telah lama dikenal secara empiris oleh masyarakat dayak di Kalimantan Tengah sebagai tanaman herbal alami untuk mengobati penyakit kuning. Penelitian ini bertujuan untuk mengetahui efek antibakteri dari ekstrak batang akar kuning terhadap bakteri Staphylococcus aureus dan Escherichia coli dan dilakukan di Laboratorium Farmakologi, dan Laboratorium Mikrobiologi Fakultas Kedokteran Universitas Sam Ratulangi. Jenis penelitian ini eksperimental laboratorium dengan metode modifikasi Kirby-Bauer. Uji efek antibakteri menggunakan metode sumuran. Esktrak batang akar kuning diperoleh dari proses maserasi dengan etanol 96%. Hasil penelitian memperlihatkan akuades sebagai kontrol negatif tidak menimbulkan zona hambat di sekitar sumur. Siprofloksasin sebagai kontrol positif memiliki diameter zona hambat yang paling besar. Rerata diameter zona hambat yang dihasilkan oleh siprofloksasin 39,23 mm terhadap Staphylococcus aureus dan 40,95 mm terhadap Escherichia coli. Ekstrak akar kuning menghasilkan rerata diameter zona hambat sebesar 12,27 mm terhadap Staphylococcus aureus dan 14,44 mm terhadap Escherichia coli. Simpulan: Ekstrak batang akar kuning berpotensi memiliki efek antibakteri terhadap bakteri Staphylococcus aureus dan Escherichia coli. Kata kunci: antibakteri, ekstrak akar kuning, staphylococcus aureus, escherichia coli

scholarly journals Uji Aktivitas Antibakteri Ekstrak Etanol Daun Ketapang (Terminalia catappa L.) Warna Hijau dan Warna Merah serta Kombinasinya

2018 ◽  
Vol 1 (2) ◽  
Author(s):  
Munira Munira Munira ◽  
Rasidah Rasidah Rasidah ◽  
Eva Melani Melani ◽  
Noni Zakiah Zakiah ◽  
Muhammad Nasir Nasir
Keyword(s):  
Staphylococcus Aureus ◽  
Leaf Extract ◽  
Ethanol Extract ◽  
Average Diameter ◽  
Inhibition Zone ◽  
Negative Control ◽  
Green Leaf ◽  
Diffusion Method ◽  
Bacteria Growth ◽  
Terminalia Catappa

ABSTRAKDaun ketapang (Terminalia catappa L.) adalah tanaman yang sering dimanfaatkan oleh masyarakat sebagai tanaman obat tradisional. Penelitian ini dilakukan untuk mengetahui pengaruh ekstrak etanol daun ketapang warna hijau, warna merah, kombinasi daun warna hijau dan daun warna merah terhadap pertumbuhan bakteri Staphylococcus aureus. Penelitian ini bersifat eksperimental dengan menggunakan Rancangan Acak Lengkap (RAL) dengan 4 perlakuan yaitu P0 (aquadest sebagai kontrol negatif), P1 (ekstrak etanol daun hijau), P2 (ekstrak etanol daun merah), dan P3 (kombinasi ekstrak etanol daun ketapang berwarna hijau dan merah) dan masing-masing 3 kali ulangan. Uji mikrobiologi menggunakan metode difusi. Berdasarkan hasil uji Anova menunjukkan bahwa ekstrak daun ketapang sangat berpengaruh terhadap pertumbuhan Staphylococcus aureus (P=0,000).Berdasarkan hasil uji lanjut Duncan rata-rata diameter zona hambat yang terbentuk menunjukkan bahwa kombinasi ekstrak daun ketapang warna hijau dan warna merah memiliki zona hambat yang lebih besar (30,92 mm) dan berbeda nyata dengan ekstrak daun ketapang berwarna hijau (21,92 mm), akan tetapi tidak berbeda nyata dengan ekstrak daun ketapang warna merah (26,42 mm).Dari hasil penelitian ini dapat disimpulkan bahwa ekstrak daun ketapang dapat menghambat pertumbuhan bakteri Staphylococcus aureus.Kata kunci: Terminalia catappa L., diameter zona hambat, Staphylococcus aureus Ketapang leaf (Terminalia catappa L.) is a plant that is often used by the community as a traditional medicinal plant. This research was conducted to determine the effect of ethanol extract of green ketapang leaves, red color, combination of green leaf and red leaf color to Staphylococcus aureus bacteria growth. This research was experimental by using Completely Randomized Design (RAL) with 4 treatments which is  P0 (aquadest as negative control), P1 (green leaf ethanol extract), P2 (red leaf ethanol extract), and P3 (combination of green leaf ketapang ethanol extract and red) and each of them repeated 3 times. Microbiology test using diffusion method. Based on the results of Anova test showed that ketapang leaf extract greatly affect the growth of Staphylococcus aureus (P=0.000). Based on the results of further test Duncan average diameter of the inhibition zone that was formed showed that the combination of green leaf and red colored leaf extract has a larger inhibition zone (30.92 mm) and significantly different with green leaf ketapang leaf extract (21.92 mm), but not significantly different with the extract of red leaf ketapang (26.42 mm). From the results of this study can be concluded that ketapang leaf extract can inhibit the growth of Staphylococcus aureus.Keywords: Terminalia catappa L., inhibition zone diameter, Staphylococcus aureus 

scholarly journals Effectiveness of Chinese Leaf Extract and Leaf Plants (Jatropha Multifida L.) As Antibacterial to Bacterial Growth Staphylococcus Aureus In Vitro

2018 ◽  
pp. 29-33
Author(s):  
Dwi Anggita ◽  
Yusriani Yusriani ◽  
Dian Amelia Abdi ◽  
Vivin Desiani
Keyword(s):  
Staphylococcus Aureus ◽  
Leaf Extract ◽  
Average Diameter ◽  
Inhibition Zone ◽  
Positive Control ◽  
Diffusion Method ◽  
Leaf Extracts ◽  
The Difference ◽  
Jatropha Multifida

Jatropha multifida L. contains alkaloids, tannins, flavonoids, saponins and phenolic acids that differ from each part of the plant and the content of these substances is what makes L. multifida Jatropha has a function as an antibacterial so that the leaf extract and the gap of chinese distance ( Jatropha multifida L.) allegedly capable of inhibiting the growth of Staphylococcus aureus bacteria. The aim of this research was to know the effectivity of leaf extract and gum of Jatropha multifida L. to the growth of Staphylococcus aureus bacteria in vitro.Penelitian used true experimental post test design. Using disc diffusion method with concentration 25; 50; 75; and 100% v / v leaf and gum china distance. Positive control was used Clindamycin 5μg drip antibiotic paper disc. The data were analyzed descriptively. The result of the research showed the difference of different inhibition zone between treatments. In chinese leaf extracts showed different mean diameters, at concentrations of 25%, 50%, 75% with inhibit zone formed respectively 0 mm, 9.32 mm, and 17.48 mm and the highest inhibition zone at concentration of 100% with an average diameter of 22.24 mm. In the gap of chinese distance showed a different mean diameter, at concentrations of 25%, 50%, 75% with the inhibit zone formed respectively 16.08 mm, 18.15 mm, and 18.63 mm and the highest inhibition zone at a concentration of 100% with an average diameter of 21.91 mm. Clindamycin positive controls show an average inhibit zone of 23.31 mm. It was concluded that there was an effect of leaf extract and resin of chinese distance plant (Jatropha multifida L.) on growth of Staphylococcus aureus bacteria, and the best concentration was 100% concentration and almost closer to the inhibitory zone of Clindamycin antibiotics as positive control.

scholarly journals POTENSI EKSTRAK DAUN TERATAI (Nymphaea pubescens L.) DALAM MENGHAMBAT Staphylococcus aureus

2017 ◽  
Vol 3 (2) ◽  
pp. 129-141
Author(s):  
Alfia Sabban ◽  
Dominggus Rumahlatu ◽  
Theopilus Watuguly
Keyword(s):  
Staphylococcus Aureus ◽  
Leaf Extract ◽  
Ornamental Plants ◽  
Inhibition Zone ◽  
Positive Control ◽  
Negative Control ◽  
Bacterial Activity ◽  
Diffusion Method ◽  
Lotus Leaf ◽  
X 24

Background: The lotus (Nymphaea pubescens L.) is one of the ornamental plants that many people in demand because it has varieties, shapes, and color of flowers are diverse. The lotus has the potential to be developed as an antibacterial. This study aims to determine the use of lotus leaf extract as anti-bacterial Staphylococcus aureus. Method: This study included the making of extraction using maceration method using ethanol, phytochemical testing of lotus leaf extract and testing of anti bacterial activity was done by diffusion method agar by observing and measuring the inhibition zone diameter formed on Muller Hinton (MHA) media. Then done by giving lotus leaf extract with 3 treatment of concentration that is 5%, 10%, 20%, positive control (ampicillin) and negative control (aquades). With an incubation period of 1 x 24 hours. Result: The result of phytochemical test showed that lotus leaf extract contain alkaloid compound, triterpenoid, steroid, flavonoid, phenolic and saponin. Anti-bacterial activity test results showed that the concentration given was not able to inhibit the growth of test bacteria. Conclusions: Bacteriostatic tests with a 60% extract concentration indicating that at 10-5 to 10-9 dilutions there were no bacterial colonies growing.

scholarly journals IN VITRO ANTIBACTERIAL EFFECT OF AQUEOUS EXTRACT OF SIDDHARTAKA SNANA USED IN TREATMENT OF VICARCHIKA (ECZEMA)

2021 ◽  
pp. 94-98
Author(s):  
E.R.H.S.S. Ediriweera ◽  
A.M.H.Y Perera ◽  
R. Senavirathne ◽  
R. Rajapaksha
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Skin Diseases ◽  
Antibacterial Effect ◽  
Inhibition Zone ◽  
Cyperus Rotundus ◽  
Diffusion Method ◽  
Disc Diffusion ◽  
Disc Diffusion Method

Vicarchika is a type of Kushta Roga (skin disease). It can be correlated with eczema. Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa are some of the bacteria which cause skin diseases. Siddhartaka Snana is a herbal bath that is described in Charaka Samhita as a treatment for Kushta Roga. Siddhartaka Snana is a herbal preparation which consists ten herbs namely; Cyperus rotundus, Catunaregum spinosa, Phyllanthus emblica, Terminalia chebula, Terminalia bellarica, Cassia fistula, Pongamia pinnata, Holarrhena antidysentrica, Alastonia scholaris and Coscinum fenestratum. Antibacterial effect of Siddhartaka Snana against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa that are responsible for skin diseases was studied using disc diffusion method and well diffusion methods. In disc diffusion method, no inhibition zone was observed with any of the tested bacteria. However, an inhibition zone of 9.67mm was observed against Staphylococcus aureus in well diffusion method with Siddhartaka Snana. Minimum Inhibitory Concentration (MIC) of Siddhartaka Snana against Staphylococcus aureus was 0.9225 mg/1ml. Ingredients of Siddhartaka Snana contain tannins, phenols and flavonoids, all of which possess antibacterial properties. Antibacterial effect of Siddhartaka Snana may have been exhibited due to actions of these phytochemicals. It was concluded that Siddhartaka Snana has an antibacterial effect against Staphylococcus aureus.

scholarly journals EFEKTIVITAS EKSTRAK DAUN MENGKUDU (Morinda citrifolia L.) DAN DAUN SIRIH MERAH (Piper crocatum Ruiz & Pav) TERHADAP ZONA HAMBAT PERTUMBUHAN Staphylococcus aureus

2017 ◽  
Vol 10 (01) ◽  
Author(s):  
F.E Afiff ◽  
Susie Amilah
Keyword(s):  
Staphylococcus Aureus ◽  
Growth Inhibition ◽  
Leaf Extract ◽  
Inhibition Zone ◽  
Morinda Citrifolia ◽  
Diffusion Method ◽  
Betel Leaf ◽  
Growth Inhibition Zone ◽  
Large Growth ◽  
Method Paper

Has conducted research on the effectiveness of various concentrations of noni leaf extract (Morinda citrifolia L.) And red betel leaf (Piper crocatum Ruiz & Pav) the growth inhibition zone of staphylococcus aureus. Inhibition test using paper disc diffusion method. Paper discs soaked in noni leaf extract and red betel leaf for 30 minutes and placed on media that has been spread bacteria staphylococcus aureus and then incubated for 24 hours. The results showed that noni leaf extract and red betel leaves with a concentration of 40%, 60% and 80% affecting large growth inhibition zone of Staphylococcus aureus.

Phytochemical analysis, Antimicrobial and Antioxidant assay of Bhut Jolokia pepper

2021 ◽  
pp. 3775-3778
Author(s):  
Dharani Dharan ◽  
K. Venkatesh ◽  
S.S. Meenambiga ◽  
Dhivya Dhanasekar ◽  
P. Arumugam
Keyword(s):  
Staphylococcus Aureus ◽  
Ethanolic Extract ◽  
Inhibition Zone ◽  
Diffusion Method ◽  
Phytochemical Analysis ◽  
Zone Of Inhibition ◽  
Antioxidant Assay ◽  
Dpph Scavenging ◽  
Bhut Jolokia ◽  
Antimicrobial Assay

The presented work represents phytochemical analysis, Antioxidant assay and Antimicrobial activity of Bhut jolokia pepper (Capsicum chinense Jacq) extracted by ethanol as solvent. The ethanolic extract of Bhut jolokia pepper showed the presence of terpenoids, steroids, saponins and flavonoids. Antimicrobial assay was done with varying concentration (250-1000µg/ml) of pepper extract using tetracycline as control by well diffusion method, the extract at 750µg/ml shown best inhibition zone and Staphylococcus aureus showed the highest zone of inhibition at all concentration compared to other bacteria species with maximum zone of inhibition of 27mm. The DPPH scavenging assay for antioxidant activity at 517nm showed positive activity for scavenging, scavenging increased with the concentration of extract. Thus, Bhut jolokia could be effective in treating diseases caused by Staphylococcus aureus from antimicrobial assay result.

scholarly journals Daya Antibakteri Ekstrak Daun Seledri (Apium graveolens L.) terhadap Porphyromonas gingivalis

2019 ◽  
Vol 16 (2) ◽  
pp. 53
Author(s):  
Anisa Luthfiyani ◽  
Peni Pujiastuti ◽  
Melok Aris W.
Keyword(s):  
Porphyromonas Gingivalis ◽  
Leaf Extract ◽  
Antibacterial Effect ◽  
Test Method ◽  
Apium Graveolens ◽  
Diffusion Method ◽  
Antibacterial Test

Background: celery leaves contain antibacterial substances that can be used as medicine. These contents include flavonoids, saponins and tannins. Purpose: the aim of this study was to determine the antibacterial effect of celery leaves (Apium graveolens L.) on the growth of Porphyromonas gingivalis (P. gingivalis). Methods: celery leaves were extracted by maceration method with 96% ethanol. The antibacterial test method against P. gingivalis using the well diffusion method on BHI-A media. The concentrations of celery leaf extract used in this study were 6.25%, 12.5%, 25%, 50% and 100%. Result: The results showed that celery leaves extract (Apium graveolens L.) didn’t have the ability to inhibit the growth of Porphyromonas gingivalis. Conclusion: celery leaves didn’t have antibacterial effect against Porphyromonas gingivalis in 6,25%, 12.5%, 25%, 50% and 100% concentrations.

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