scholarly journals Use of prostaglandin synthetic analogue E1 for uterus cervix preparation and labor induction

2003 ◽  
Vol 2 (3) ◽  
pp. 75-80
Author(s):  
I. D. Yevtushenko ◽  
A. Sh. Makhmutkhodzhayev ◽  
T. V. Ivanova ◽  
O. V. Parshina ◽  
I. A. Ryzhova ◽  
...  

A clinical prospective examination of 90 women with complete pregnancy and indications for labor induction because of unsatisfactory maturity of uterus cervix has been made. The aim was to create a comparative analysis of efficiency of intravaginal introduction of prostaglandin synthetic analogue E1 misoprostol («Sytotec») and intracervical introduction of prostaglandin E2 dinoprostone («Prepidil» gel) for uterus cervix preparation and labor induction at complete pregnancy. Misoprostol in a dose of 25 mkg has been introduced to pregnant women of the 1 group (n=44), every 4 hours not more than 3 times. In case of discharge of waters or labor activity the second introduction has not been done. Dinoprostone has been introduced intracervically in a single dose to pregnant women of the 2 group (n=46). The use of misoprostol has been accompanied by spontaneous beginning of labor activity by 2 times more often than the use of dinoprostone. The quantity of vaginal births within 12 and 24 hours of observation has been surely greater and the duration of time between the beginning of introduction and labor has been surely smaller in the group of women received misoprostol as compared to the one received dinoprostone. It has not been revealed any differences between examined groups by the frequency of uterus hyperstimulation symptom development, labor duration, frequency of abdominal and vaginal labor, as well as perinatal outcomes.

Author(s):  
Jorge Duro Gómez ◽  
Marta Porras Lucena ◽  
Vendrell Aranda Celia María

Objectives: To compare the effectiveness (hours until delivery) and safety (rate of vaginal deliveries and caesarean sections, use of oxytocin and perinatal outcomes) of dinoprostone and Cook's balloon as a method of labor induction in pregnant women with fetuses with an estimated weight below the 10th percentile and normal Doppler. Methods: retrospective cohort review of pregnant women with small for gestational age fetuses and induced with both methods in Reina Sofía Hospital, Cordoba, Spain from 2014 to 2018. The main outcome was time until delivery. Descriptive characteristics, obstetric and perinatal outcomes were analyzed. 322 pregnant women were induced: 204 women were induced with Cook's balloon (CB) and 118 with dinoprostone (DIN). RESULTS: Dinoprostone decreases the time until delivery (28.86 vs. 24.32 hours with CB and DIN, respectively, p<0.0001) and the use of oxytocin (79.7% vs 54.2% in CB and DIN group; p<0,01), as compared to Cook's balloon. No differences were observed in the rate of caesarean sections and vaginal deliveries, as well as in perinatal results. Conclusion: DIN reduces the time to delivery compared to CB with a lower need for oxytocin. Moreover, without worse perinatal outcomes.


GYNECOLOGY ◽  
2018 ◽  
Vol 20 (4) ◽  
pp. 19-25
Author(s):  
N A Kurmacheva ◽  
I E Rogozhina ◽  
Yu V Chernenkov ◽  
O S Panina

The goal is to justify the principles of prevention and correction of micronutrient deficiency in mother and child on the basis of a comparative analysis of the health status of pregnant women and newborns in different conditions of provision with vitamins and minerals. Materials and methods. A comparative analysis of the clinical and biochemical results of a survey of 376 mothers and their children in the period of newborns. The study of the content of the main micronutrients in the blood and breast milk, ioduria in mothers, comparison obstetric and perinatal outcomes depending on the availability of women with vitamins and microelements during pregnancy. Results. Data on high frequency of polyhypovitaminosis (72.6%), hypo-microelementosis (19.4-45.2%), iodine deficiency in pregnant women, low concentration vitamins A, B1, B2, C, b-carotenoids, iodine, iron, zinc, selenium in breast milk in lactating, not receiving vitamin-mineral preparations. It is proved that the intake of women from the early stages of pregnancy is a balanced vitamin-mineral complex Elevat® Pronatal and potassium iodide at a dose of 250 mcg/day normalizes their micronutrient supply and significantly reduces the incidence of complications pregnancy, delivery in mothers, diseases and pathological conditions in newborns (in 1.3-3 times, p


2020 ◽  
Author(s):  
Pengming Sun ◽  
Hangjing Gao ◽  
Xiqi Huang ◽  
Huanrui Zheng ◽  
Hongning Cai ◽  
...  

2019 ◽  
Vol 15 (2) ◽  
pp. 143-149 ◽  
Author(s):  
Harpriya Kaur ◽  
Delf Schmidt-Grimminger ◽  
Baojiang Chen ◽  
K.M. Monirul Islam ◽  
Steven W. Remmenga ◽  
...  

Background: Pregnancy may increase the risk of Human Papillomavirus (HPV) infection because of pregnancy induced immune suppression. The objective of this study was to use a large population-based dataset to estimate the prevalence of HPV infection and its association with adverse outcomes among pregnant women. Methods: We analyzed Pregnancy Risk Monitoring System data from 2004-2011 (N=26,085) to estimate the self-reported HPV infection. Survey logistic procedures were used to examine the relationship between HPV infection and adverse perinatal outcomes. Results: Approximately 1.4% of women were estimated to have HPV infection during their pregnancy. The prevalence of adverse outcomes in this sample was preterm birth (8.4%), preeclampsia (7.5%), low birth weight (6.3%) and premature rupture of membranes (2.8%). Compared to women without HPV infection, HPV infection positive women were much more likely to have had other infections such as chlamydia (9.23% vs. 2.12%, p-value <.0001), Group B Strep (21.7% vs. 10.04%, p-value <.0001), and herpes (7.17% vs. 1.07%, p-value <.0001). After adjusting for other risk factors including other infections, HPV infection was significantly associated with low birth weight (OR: 1.94, 95% CI: 1.14-3.30). Conclusion: The study indicated a potential association between HPV infection and low birth weight. Because pregnant women with HPV infection are at higher risk of other infections, future research may focus on the roles of co-infection in the development of adverse perinatal effects.


2015 ◽  
Vol 40 (2) ◽  
pp. 52-57 ◽  
Author(s):  
M Sharmeen ◽  
PA Shamsunnahar ◽  
TR Laita ◽  
SB Chowdhury

Objectives: Thyroid disorders are among the common endocrine problems in pregnant women. It is now well established that not only overt but subclinical thyroid dysfunction also has adverse effects on maternal and fetal outcome. There are few data from Bangladesh about the prevalence of thyroid dysfunction in pregnancy. With this background, this study aims to find out thyroid dysfunction (both overt and subclinical hypothyroidism) in pregnancy and its impact on obstetrical outcome.Methods: We studied the evaluation of 50 admitted pregnancies corresponding to 29 women with subclinical hypothyroidism and rest 21 was overt hypothyroidism. Detailed history and examination were performed. Apart from routine obstetrical investigations, Thyroid Stimulating Hormone (TSH) estimation was done. Their obstetrical and perinatal outcomes were noted.Results: Overt hypothyroidism was significantly (p<0.05) higher in 25 to 44 years age group. However two and three abortions were significantly (p<0.05) higher in overt hypothyroidism patients. In sub clinical hypothyroidism 86.2% conceived firstly within 2 years and 66.7% in overt hypothyroidism patients conceived firstly in between 3 to 5 years after marriage. Overt hypothyroids were prone to have pregnancy-induced hypertension 42.9%, intrauterine growth restriction (P=0.001) and gestational diabetes (38.1%) as compared to subclinical cases. Neonatal complications were significantly more in overt hypothyroidism group. Mean TSH level was significantly (p<0.05) higher in overt hypothyroidism patients but mean FT4 level was almost similar in both groups. Majority of the patient underwent caesarean section in both groups due to associated medical and obstetrical complications. None of the babies showed hypothyroidism by cord blood tests. In this analysis our results showed that overt hypothyroidism among Bangladeshi pregnant women are associated with more maternal complication & adverse parental outcome than subclinical hypothyroidism. The adequate treatment of hypothyroidism during gestation minimizes risks and generally, makes it possible for pregnancies to be carried to term without complications. Significant adverse effects on maternal and fetal outcome were seen emphasizing the importance of routine antenatal thyroid screening.Bangladesh Med Res Counc Bull 2014; 40 (2): 52-57


Viruses ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 853
Author(s):  
Sara Cruz Melguizo ◽  
María Luisa de la Cruz Conty ◽  
Paola Carmona Payán ◽  
Alejandra Abascal-Saiz ◽  
Pilar Pintando Recarte ◽  
...  

Pregnant women who are infected with SARS-CoV-2 are at an increased risk of adverse perinatal outcomes. With this study, we aimed to better understand the relationship between maternal infection and perinatal outcomes, especially preterm births, and the underlying medical and interventionist factors. This was a prospective observational study carried out in 78 centers (Spanish Obstetric Emergency Group) with a cohort of 1347 SARS-CoV-2 PCR-positive pregnant women registered consecutively between 26 February and 5 November 2020, and a concurrent sample of PCR-negative mothers. The patients’ information was collected from their medical records, and the association of SARS-CoV-2 and perinatal outcomes was evaluated by univariable and multivariate analyses. The data from 1347 SARS-CoV-2-positive pregnancies were compared with those from 1607 SARS-CoV-2-negative pregnancies. Differences were observed between both groups in premature rupture of membranes (15.5% vs. 11.1%, p < 0.001); venous thrombotic events (1.5% vs. 0.2%, p < 0.001); and severe pre-eclampsia incidence (40.6 vs. 15.6%, p = 0.001), which could have been overestimated in the infected cohort due to the shared analytical signs between this hypertensive disorder and COVID-19. In addition, more preterm deliveries were observed in infected patients (11.1% vs. 5.8%, p < 0.001) mainly due to an increase in iatrogenic preterm births. The prematurity in SARS-CoV-2-affected pregnancies results from a predisposition to end the pregnancy because of maternal disease (pneumonia and pre-eclampsia, with or without COVID-19 symptoms).


2020 ◽  
pp. 105477382098491
Author(s):  
Hülya Türkmen ◽  
Serap Çetinkaya ◽  
Hafize Kiliç ◽  
Emine Apay ◽  
Devrim Karamüftüoğlu ◽  
...  

This randomized controlled experimental study was conducted with an intervention group ( n = 61) and a control group ( n = 63) consisting of primipara pregnant women. The pregnant women in the intervention group were asked to focus their attention on Maryam’s flower opening its leaf buds and imagine the labor’s progress during the course of their labor. The VAS was administered to each group at specific times (at 4–5 cm, 6–7 cm, 8–9 cm cervical dilatation) to determine their level of labor pain. A statistically significant difference was found between the groups’ mean pain scores at 4–5 cm, 6–7 cm, and 8–9 cm cervical dilatation ( p < .05). The labor duration of the pregnant women in the intervention group was significantly shorter than that of the pregnant women in the control group ( p = .017). The physical comfort level of the intervention group was significantly higher than that of the control group at 8–9 cm cervical dilatation ( p = .039).


2021 ◽  
pp. 1-11
Author(s):  
Velichka Traneva ◽  
Stoyan Tranev

Analysis of variance (ANOVA) is an important method in data analysis, which was developed by Fisher. There are situations when there is impreciseness in data In order to analyze such data, the aim of this paper is to introduce for the first time an intuitionistic fuzzy two-factor ANOVA (2-D IFANOVA) without replication as an extension of the classical ANOVA and the one-way IFANOVA for a case where the data are intuitionistic fuzzy rather than real numbers. The proposed approach employs the apparatus of intuitionistic fuzzy sets (IFSs) and index matrices (IMs). The paper also analyzes a unique set of data on daily ticket sales for a year in a multiplex of Cinema City Bulgaria, part of Cineworld PLC Group, applying the two-factor ANOVA and the proposed 2-D IFANOVA to study the influence of “ season ” and “ ticket price ” factors. A comparative analysis of the results, obtained after the application of ANOVA and 2-D IFANOVA over the real data set, is also presented.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Shigeki Koshida ◽  
Shinsuke Tokoro ◽  
Daisuke Katsura ◽  
Shunichiro Tsuji ◽  
Takashi Murakami ◽  
...  

AbstractMaternal perception of decreased fetal movement is associated with adverse perinatal outcomes. Although there have been several studies on interventions related to the fetal movements count, most focused on adverse perinatal outcomes, and little is known about the impact of the fetal movement count on maternal behavior after the perception of decreased fetal movement. We investigated the impact of the daily fetal movement count on maternal behavior after the perception of decreased fetal movement and on the stillbirth rate in this prospective population-based study. Pregnant women in Shiga prefecture of Japan were asked to count the time of 10 fetal movements from 34 weeks of gestation. We analyzed 101 stillbirths after the intervention compared to 121 stillbirths before the intervention. In multivariable analysis, maternal delayed visit to a health care provider after the perception of decreased fetal movement significantly reduced after the intervention (aOR 0.31, 95% CI 0.11–0.83). Our regional stillbirth rates in the pre-intervention and post-intervention periods were 3.06 and 2.70 per 1000 births, respectively. Informing pregnant women about the fetal movement count was associated with a reduction in delayed maternal reaction after the perception of decreased fetal movement, which might reduce stillbirths.


2021 ◽  
pp. 016344372110227
Author(s):  
Yingzi Wang ◽  
Thoralf Klein

This paper examines the changes and continuities in TV representations of Chinese Communist Party’s revolutionary history and interprets them within the broader context of China’s political, economic and cultural transformations since the 1990s. Drawing on a comparative analysis of three state-sponsored TV dramas produced between the late 1990s and mid-2010s, it traces how the state-sanctioned revolutionary narratives have changed over time in response to the Party’s propaganda imperatives on the one hand, and to the market-oriented production environment on the other. The paper argues that while recent TV productions in the new century have made increasing concessions to audience taste by adopting visually stimulating depictions and introducing fictional characters as points of identification for the audience, the revolutionary narratives were still aligned with the Party’s propaganda agenda at different times. This shows the ongoing competition between ideological and commercial interests in Chinese TV production during the era of market reforms.


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