scholarly journals PERBEDAAN PROFIL LIPID DAN KADAR ASAM URAT PADA PASIEN DIABETES MELITUS TIPE II DENGAN DAN TANPA HIPERTENSI

2017 ◽  
Vol 4 (3) ◽  
pp. 189
Author(s):  
Filliana Savitri ◽  
Intani Kurnia Savitri ◽  
Pugud Samodro ◽  
Lantip Rujito
Keyword(s):  
Uric Acid ◽  
Total Cholesterol ◽  
Average Rate ◽  
Hdl Cholesterol ◽  
Cross Sectional ◽  
Hospital District ◽  
Cross Sectional Design ◽  
Total Test ◽  
Diabetes Melitus

Diabetes Mellitus type 2 is the 7th world of death problem with the 95% proportion rate. Hypertension has also a correlation with this condition. The mortality of cardiovascular is 2-3 times over from diabetics with hypertension than diabetics with normotension which caused by lipid and aciduric disturbations. This study was conducted using cross-sectional design. Twenty-five sample of diabetics normotension and 25 sample of diabetics patient along with hypertension in Ajibarang Hospital District Banyumas and comply with inclusion-exclusion criteria were taken suing consecutive sampling. Data from the cholesterol and triglyceride total test were collected and analyzed with Mann-Whitney test. Additionally, HDL cholesterol and LDL was analyzed using T-Test.  This Study showed that average total cholesterol from diabetics along with hypertension patients was in a range of 185.16 ± 36.59 and Diabetics patient without hypertension was 196.76 ± 44.62 (p = 0,503). Besides, the average rate of triglyceride level on diabetics patient with hypertension was 181.76 ±72.68 and diabetics patient along without hypertension was 180.28 ± 125.75 (p=0,367). The average rate of HDL cholesterol level on diabetics patient with hypertension was 39.12 ± 11.07 and diabetics patient along without hypertension was 42.37 ± 14.98  (p = 0,387). In addition, Average rate of LDL level on diabetics patient with hypertension was 112.57 ± 24.77 and diabetics patient along without hypertension was 118.33 ± 37.41 (p = 0,524). The average rate of uric acid on diabetics patient with hypertension was  6,120 ± 1,45 and diabetics patient along without hypertension was 5,768 ± 2,45 (p=0,200).  As a conclusion, there is no difference with total cholesterol, triglyceride, HDL, LDL cholesterol, and uric acid significant from diabetics patient with or without hypertension in Ajibarang Hospital District Banyumas in 2016.

scholarly journals Hubungan Antara Tekanan Darah Sistolik Dengan Kadar Hdl Kolesterol Pada Pasien Diabetes Melitus Tipe 2 Di Klinik Arafah Lampung Tengah

2021 ◽  
Vol 1 (4) ◽  
pp. 307-314
Author(s):  
Toni Prasetia ◽  
Firhat Esfandiari ◽  
Sandhy Arya Pratama ◽  
Ikbal Zaenur Ridwan
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Systolic Blood Pressure ◽  
Hdl Cholesterol ◽  
Cross Sectional ◽  
Cholesterol Levels ◽  
Diabetes Melitus

ABSTRACT: RELATIONSHIP BETWEEN SYSTOLIC BLOOD PRESSURE AND HDL CHOLESTEROL LEVELS IN TYPE 2 DIABETES MELLITUS PATIENTS IN ARAFAH CLINIC, CENTRAL LAMPUNG Background: Hypertension is a major risk factor for type 2 Diabetes Mellitus, hypertension can make cells insensitive to insulin, so blood sugar levels can also be disrupted. Dyslipidemia causes constriction in blood vessels or atherosclerosis which can aggravate hypertension or diabetes mellitus. Meanwhile, the function of HDL in transporting bad cholesterol also causes blood vessels to dilate due to increased NO production. Objective: To find out the relationship between systolic blood pressure and HDL cholesterol levels in type 2 diabetes mellitus patients at the Arafah Clinic, Central Lampung, 2020. Method: This type of research used in this research is descriptive-analytic with cross-sectional design. The sampling technique was total sampling. Respondents in this study were patients with Type 2 Diabetes Mellitus at the Arafah Clinic in Central Lampung in 2020 Results: Based on the results of the chi-square statistical test, it was found that there was no relationship with the results of p = 0.898 (p> 0.05). Conclusion: There is no correlation between systolic blood pressure and HDL cholesterol levels in type 2 diabetes mellitus patients at the Arafah Clinic, Central Lampung in 2020. Keywords: Diabetes Mellitus type 2, Systolic Blood Pressure, HDL   INTISARI: HUBUNGAN TEKANAN DARAH SISTOLIK DENGAN KADAR KOLESTEROL HDL PADA PASIEN DIABETES MELLITUS TIPE 2 DI KLINIK ARAFAH LAMPUNG TENGAH Latar Belakang: Hipertensi merupakan faktor risiko utama untuk terjadinya Diabetes Melitus tipe 2, hipertensi dapat membuat sel tidak sensitif terhadap insulin, maka kadar gula di dalam darah juga dapat mengalami gangguan. Dislipidimia menyebabkan terjadinya penyempitan dalam pembuluh darah atau aterosklerosis yang dapat memperberat kondisi hipertensi ataupun diabetes mellitus. Sedangkan fungsi HDL mengangkut kolesterol jahat juga menyebabkan pembuluh darah bisa berdilatasi karena produksi NO yang meningkat.Tujuan: Untuk mengetahui Hubungan Antara Tekanan Darah Sistolik dengan Kadar HDL Kolesterol pada pasien Diabetes Melitus tipe 2 di Klinik Arafah Lampung Tengah Tahun 2020.Metode: Jenis penelitian yang digunakan dalam penelitian ini adalah deskriptif analitik dengan desain cross sectional. Teknik pengambilan sampel berupa total sampling. Responden dalam penelitian ini adalah pasien Diabetes Melitus tipe 2 di Klinik Arafah Lampung Tengah.Hasil: Berdasarkan hasil uji statistic chi-square didapatkan tidak terdapat hubungan dengan hasil p=0,898 (p>0,05).Kesimpulan: Tidak terdapat Hubungan Antara Tekanan Darah Sistolik dengan Kadar HDL Kolesterol pada pasien Diabetes Melitus tipe 2 di Klinik Arafah Lampung Tengah tahun 2020. Kata Kunci     : Diabetes Melitus tipe 2, Tekanan Darah Sistolik, HDL

scholarly journals The Correlation between Fat Consumption and Atherogenic Index on Type 2 Diabetes Melitus Patients in dr. Soebandi Hospital

2018 ◽  
Vol 4 (1) ◽  
pp. 7
Author(s):  
Mega Ratnasari ◽  
Ali Santosa ◽  
Dwita Aryadina Rahmawati
Keyword(s):  
Type 2 Diabetes ◽  
Atherogenic Index ◽  
Cross Sectional ◽  
Carbohydrate Consumption ◽  
Fat Consumption ◽  
Spearman Correlation Test ◽  
Cross Sectional Design ◽  
Dm Type 2 ◽  
Diabetes Melitus

One of the risk factor that can be changed in type 2 diabetes melitus is food consumption. Fat is one of the macronutrients that have significant influence in consumption. Unhealthy diet can be a trigger to macrovascular complication that is coronary heart disease (CHD) which started with atherosclerosis. Atherogenic index is a good predictor for CHD. This study aims to determine the correlation between fat consumption with atherogenic index in DMT 2 patients at RSD dr. Soebandi. This is an analitic observational study with cross sectional design, using 74 type 2 diabetes melitus patients from Internal Poly at RSD dr. Soebandi who met inclusion and exclusion criteria. Fat consumption were obtained with 24-hours food recall interview and atherogenic index were obtained from TG and HDL levels in medical record. The average of fat consumption is 34,01% and as much 33 subjects (44,6%) have high risk of CHD (AI>0,21). Spearman correlation test between fat consumption with atherogenic index is p=0,025 which mean there is significant correlation between fat consumption and atherogenic index in type 2 diabetes melitus patients at RSD dr. Soebandi Keywords: DM Type 2, fat consumption, carbohydrate consumption, atherogenic index               

scholarly journals Faktor yang Berhubungan dengan Deformitas Kaki pada Penyandang Diabetes Melitus Tipe 2

2021 ◽  
Vol 4 (2) ◽  
pp. 654-662
Author(s):  
Desi Susanti ◽  
Dita Amita
Keyword(s):  
Diabetes Mellitus ◽  
Analytic Method ◽  
Foot Deformity ◽  
Cross Sectional ◽  
Factors Associated ◽  
Type 2 Dm ◽  
Cross Sectional Design ◽  
And Gender ◽  
Diabetes Melitus

This study aims to explain the factors associated with foot deformity in people with type 2 diabetes. This study used a descriptive-analytic method with a cross-sectional design. The results showed that the aspects related to the incidence of foot deformity were education (P=0.022; OR=4.57), body mass index (BMI) (P=0.035; OR=0.23), and knowledge (P=0.001). ; OR = 9.17), while the factors of age (P = 0.22) and gender (P = 0.712) were not associated with the incidence of foot deformity. In conclusion, the knowledge factor is a factor that can influence nine times more strongly the incidence of foot deformity in people with type 2 DM compared to other factors.   Keywords: Foot Deformity, Diabetes Mellitus

scholarly journals Hubungan Antara Tekanan Darah Sistolik dengan Kadar Kolesterol Total pada Pasien Diabetes Melitus Tipe 2 di Klinik Arafah Lampung Tengah

2021 ◽  
Vol 3 (4) ◽  
pp. 562-569
Author(s):  
Firhat Esfandiari ◽  
Tusy Triwahyuni ◽  
Resti Arania ◽  
Najmi Bias Aysa
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Systolic Blood Pressure ◽  
Total Cholesterol ◽  
Cross Sectional ◽  
Cholesterol Levels ◽  
Diabetes Melitus

ABSTRACT: RELATIONSHIP BETWEEN SYSTOLIC BLOOD PRESSURE AND TOTAL CHOLESTEROL LEVEL IN TYPE 2 DIABETES MELLITUS PATIENTS IN ARAFAH CLINIC, CENTRAL LAMPUNG Background: Diabetes mellitus type 2 is a disease characterized by hyperglycemia, with the underlying cause being an increase in insulin resistance and or an increase in pancreatic beta cell dysfunction (Decroli, 2019). Diabetes mellitus, hypertension and increased cholesterol levels are conditions that are often found to be interrelated. Hypertension and increased cholesterol levels can be comorbid conditions that accompany DM (Noviyanti et al., 2015). Objective: This study aimed to determine the correlation between systolic blood pressure levels and total cholesterol levels in patients with type 2 diabetes mellitus at the Arafah Clinic, Central Lampung. Method: The type of research used in this research is descriptive analytic with aapproach Cross Sectional. As well as samples taken from Arafah Clinic patients diagnosed with type 2 diabetes, as many as 46 patients. Results: Based on the results of thetest, it was fisher exact found that there was no correlation with the p value = 0.735 (p> 0.05). Conclusion: H0 is received, which means there is no significant correlation between systolic blood pressure and total cholesterol levels in type 2 DM patients at the Arafah Clinic, Central Lampung. Keywords: Systolic Blood Pressure, Total Cholesterol Levels, Type 2 Diabetes Mellitus  INTISARI: HUBUNGAN ANTARA TEKANAN DARAH SISTOLIK DENGAN KADAR KOLESTEROL TOTAL PADA PASIEN DIABETES MELITUS TIPE 2 DI KLINIK ARAFAH LAMPUNG TENGAH Latar Belakang: Diabetes Melitus tipe 2 merupakan suatu penyakit dengan karakteristik hiperglikemia, dengan penyebab yang mendasarinya adalah peningkatan resistensi insulin dan atau peningkatan disfungsi sel beta pankreas (Decroli, 2019). Diabetes melitus, hipertensi dan peningkatan kadar kolesterol merupakan keadaan yang sering dijumpai saling berkaitan. Hipertensi dan peningkatan kadar kolesterol bisa menjadi kondisi komorbiditas yang menyertai DM (Noviyanti et al., 2015).Tujuan: Penelitian ini ditujukkan untuk mengetahui hubungn antara kadar tekanan darah sistolik dengan kadar kolesterol total pada pasien diabetes melitus tipe 2 di Klinik Arafah Lampung Tengah.Metodologi: Jenis penelitian yang digunakan pada penelitian ini adalah deskriptif analitik dengan pendekatan Cross Sectional. Serta sampel diambil dari pasien Klinik Arafah yang terdiagnosa DM tipe 2 yaitu sebanyak 46 pasien.Hasil: Berdasarkan dari hasil uji fisher exact didapatkan tidak adanya hubungan dengan nilai p =0,735 (p>0,05).Kesimpulan: Didapatkan H0 yang diterima yang berarti tidak ada hubungan yang signifikan antara tekanan darah sistolik dengan kadar koletesterol total pada pasien DM tipe 2 di Klinik Arafah Lampung Tengah. Kata Kunci:Tekanan Darah Sistolik, Kadar Kolesterol Total, Diabetes Melitus tipe  

THE RELATIONSHIP OF NUTRITIONAL STATUS TO URIC ACID LEVEL IN COMMUNITY OF PONDOK PESANTREN AL-HIDAYAH, NGAWI

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Marselli Widya Lestari ◽  
Tri Wahyuni Bintarti
Keyword(s):  
Uric Acid ◽  
Nutritional Status ◽  
Gouty Arthritis ◽  
Extracellular Fluid ◽  
Boarding School ◽  
Clinical Syndrome ◽  
Bivariate Analysis ◽  
Cross Sectional ◽  
Knowledge And Attitude ◽  
Cross Sectional Design

Gout or Gouty Arthritis is a degenerative disease. Gouty arthritis is a clinical syndrome that is caused by deposition of purine crystals in the tissues, due to levels of uric acid (hyperuricemia) in the extracellular fluid that passes through saturation. The etiology of gout arthritis included age, sex, history of medication, obesity, consumption of purine and alcohol. Aging is an important risk factor for men and women. This study uses an analytical-descriptive approach with cross-sectional design. This study was conducted to obtain a relationship between nutritional status and uric acid levels in the community in the area of ​​Al-Hidayah Islamic Boarding School, Ngawi. This research was conducted in Majasem Village, Kendal District, Ngawi Regency, starting from 7 June - 31 August 2018. The results showed that there was a relationship between nutritional status and uric acid levels in the community in the area of ​​Al-Hidayah Islamic Boarding School, Ngawi (p=0,008). Suggestions for further research are bivariate analysis based on gender, knowledge and attitude to response to diet so that other factors that influence can be seen clearly

Relative risk of cardiovascular disease is higher in women with type 2 diabetes, but not in those with prediabetes, as compared with men

2020 ◽  
Author(s):  
Elena Succurro ◽  
Teresa Vanessa Fiorentino ◽  
Sofia Miceli ◽  
Maria Perticone ◽  
Angela Sciacqua ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Longitudinal Study ◽  
Relative Risk ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Adverse Outcomes ◽  
Cross Sectional ◽  
Normal Glucose

<b>Objective</b>: Most, but not all studies suggested that women with type 2 diabetes have higher relative risk (RR) for cardiovascular disease (CVD) than men. More uncertainty exists on whether the RR for CVD is higher in prediabetic women compared to men. <p><b>Research Design and Methods</b>: In a cross-sectional study, in 3540 normal glucose tolerant (NGT), prediabetic, and diabetic adults, we compared the RR for prevalent non-fatal CVD between men and women. In a longitudinal study including 1658 NGT, prediabetic, and diabetic adults, we compared the RR for incident major adverse outcomes, including all-cause death, coronary heart disease, and cerebrovascular disease events after 5.6 years follow-up. </p> <p><b>Results:</b> Women with prediabetes and diabetes exhibited greater relative differences in BMI, waist circumference, blood pressure, total, LDL and HDL cholesterol, triglycerides, fasting glucose, hsCRP, and white blood cell count than men with prediabetes and diabetes when compared with their NGT counterparts. We found a higher RR for prevalent CVD in diabetic women (RR 9.29; 95% CI 4.73-18.25; <i>P</i><0.0001) than in men (RR 4.56; 95% CI 3.07-6.77; <i>P</i><0.0001), but no difference in RR for CVD was observed comparing prediabetic women and men. In the longitudinal study, we found that diabetic, but not prediabetic women have higher RR (RR 5.25; 95% CI 3.22-8.56; <i>P</i><0.0001) of incident major adverse outcomes than their male counterparts (RR 2.72; 95% CI 1.81-4.08; <i>P</i><0.0001).</p> <p><b>Conclusions:</b> This study suggests that diabetic, but not prediabetic, women have higher RR for prevalent and incident major adverse outcomes than men. </p>

Effects of diacerein intake on cardiometabolic profiles in type 2 diabetics: a systematic review and meta-analysis of clinical trials.

2020 ◽  
Vol 27 ◽  
Author(s):  
Peyman Nowrouzi-Sohrabi ◽  
Reza Tabrizi ◽  
Mohammad Jalali ◽  
Navid Jamali ◽  
Shahla Rezaei ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Body Weight ◽  
Total Cholesterol ◽  
Ldl Cholesterol ◽  
Meta Analysis ◽  
Hdl Cholesterol ◽  
Cochrane Central Register ◽  
Statistical Heterogeneity

Introduction: A systematic review and meta-analysis of clinical trials was undertaken to evaluate the effect of diacerein intake on cardiometabolic profiles in patients with type 2 diabetes mellitus (T2DM). Methods: Electronic databases such as PubMed, EMBASE, Scopus, Web of Science, Google Scholar, and Cochrane Central Register of Controlled Trials were searched from inception to 31 July 2019. Statistical heterogeneity was evaluated using Cochran’s Q test and I-square (I2 ) statistic. Data were pooled using random-effect models and weighted mean difference (WMD). Results: From 1,733 citations, seven clinical trials were eligible for inclusion and meta-analysis. A significant reduction in hemoglobin A1c (HbA1c) (WMD -0.73; 95%CI -1.25 to -0.21; P= 0.006; I2 = 72.2%) and body mass index (BMI) (WMD -0.55; 95%CI -1.03 to -0.07; P= 0.026; I2 = 9.5%) were identified. However, no significant effect of diacerein intake was identified on fasting blood sugar (FBS) (WMD - 9.00; 95%CI -22.57 to 4.57; P= 0.194; I2 = 60.5%), homeostatic model assessment for insulin resistance (HOMA-IR) (WMD 0.39; 95%CI 0.95 to 1.73; P= 0.569; I2 = 2.2%), body weight (WMD -0.54; 95%CI -1.10 to 0.02; P= 0.059), triglycerides (WMD -0.56; 95%CI -24.16 to 23.03; P= 0.963; I2 = 0.0%), total-cholesterol (WMD -0.21; 95%CI -12.19 to 11.78; P= 0.973; I2 = 0.0%), HDL-cholesterol (WMD -0.96; 95%CI -2.85 to 0.93; P= 0.321; I2 = 0.0%), and LDL-cholesterol levels (WMD -0.09; 95%CI -8.43 to 8.25; P= 0.983; I2 = 37.8%). Conclusion: Diacerein intake may reduce HbA1c and BMI; however, no evidence of effect was observed for FBS, HOMA-IR, body weight, triglycerides, total-cholesterol, HDL-cholesterol or LDL-cholesterol.

scholarly journals Normal Non-HDL Cholesterol, Low Total Cholesterol, and HDL Cholesterol Levels in Sickle Cell Disease Patients in the Steady State: A Case-Control Study of Tema Metropolis

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Richard K. D. Ephraim ◽  
Patrick Adu ◽  
Edem Ake ◽  
Hope Agbodzakey ◽  
Prince Adoba ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Steady State ◽  
Sickle Cell Disease ◽  
Total Cholesterol ◽  
Sickle Cell ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Lipoprotein Cholesterol ◽  
Cell Disease ◽  
Cross Sectional

Background.Abnormal lipid homeostasis in sickle cell disease (SCD) is characterized by defects in plasma and erythrocyte lipids and may increase the risk of cardiovascular disease. This study assessed the lipid profile and non-HDL cholesterol level of SCD patients.Methods.A hospital-based cross-sectional study was conducted in 50 SCD patients, in the steady state, aged 8–28 years, attending the SCD clinic, and 50 healthy volunteers between the ages of 8–38 years. Serum lipids were determined by enzymatic methods and non-HDL cholesterol calculated by this formula: non-HDL-C = TC-HDL-C.Results.Total cholesterol (TC) (p=0.001) and high-density lipoprotein cholesterol (HDL-C) (p<0.0001) were significantly decreased in cases compared to controls. The levels of non-HDL-C, low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) were similar among the participants. The levels of decrease in TC and HDL were associated with whether a patient was SCD-SS or SCD-SC. Systolic blood pressure and diastolic blood pressure were each significantly associated with increased VLDL [SBP,p=0.01, OR: 0.74 (CI: 0.6–0.93); DBP,p=0.023, OR: 1.45 (CI: 1.05–2.0)].Conclusion.Dyslipidemia is common among participants in this study. It was more pronounced in the SCD-SS than in SCD-SC. This dyslipidemia was associated with high VLDL as well as increased SBP and DBP.

scholarly journals HUBUNGAN KUALITAS TIDUR DENGAN KADAR GLUKOSA DARAH PUASA PADA PASIEN DIABETES MELLITUS TIPE II DI PUSKESMAS KASSI-KASSI KOTA MAKASSAR

2020 ◽  
Vol 15 (1) ◽  
pp. 46-50
Author(s):  
Muhammad Basri ◽  
Baharuddin K ◽  
Sitti Rahmatia
Keyword(s):  
Diabetes Mellitus ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Purposive Sampling ◽  
Dm Type 2 ◽  
Diabetes Melitus

Diabetes Melitus (DM) merupakan salah satu kelompok penyakit metabolik dan kronis dengan karakteristik hiperglikemia yang terjadi karena kelainan sekresi insulin, kerja insulin atau keduaduanya yang membutuhkan perawatan medis dan pendidikan pengelolaan mandiri untuk mencegah komplikasi akut jangka panjang (Nian, 2017). Tujuan penelitian ini adalah Mendeskripsikan hubungan kualitas tidur dengan kadar glukosa darah Puasa pada pasien DM tipe II di PKM Kassi-Kassikota Makassar. Manfaat : Meningkatkan pengetahuan pada Penderita DM Tipe II yang mengalami gangguan Kwalitas dan Pola Tidur shari-hari Meningkatkan pengetahuan pada Penderita DM Tipe II yang mengalami gangguan Kwalitas dan Pola Tidur shari-hari Metode : Pada penelitian ini menggunakan desain cross sectional, jenis penelitian ini menggunakan metode analitik yaitu metode penelitian yang dilakukan dengan tujuan untuk mengetahui hubungan antara Kualitas tidur dengan kadar glukosa darah puasa pada pasien DM Tipe II. Sampel menggunakan purposive sampling dengan menggunakan rumus Slovin dengan jumlah sampel  55  orang  yaitu  seluruh pasien DM tipe 2 yang menjalani rawat jalan di PKM Kassi-Kassi Kota Makassar. Hasil Uji Statistik Chi Square diperoleh p value 0,000 < 0,05.sehingga peneliti berasumsi bahwa  ada hubungan antara kualitas tidur dengan kadar glukosa darah pada pasien DM Type 2 di Puskesmas Kassi-Kassi Makassar.  Kesimpulan yaitu terdapat hubungan kualitas tidur dengan kadar glukosa darah pada pasien diabetes melitus tipe 2 di Puskesmas Kassi-Kassi Makassar. Saran dapat dijadikan sebagai salah satu acuhan bagi pasien diabetes melitus tipe 2 untuk meningkatkan kualitas tidur dan menjaga kadar glukosa darah puasa

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