scholarly journals Considering Sex and Gender in Epidemiology: a Challenge Beyond Terminology – Methodological Research

Author(s):  
Helene Colineaux ◽  
Alexandra Soulier ◽  
Benoit Lepage ◽  
Michelle Kelly-Irving

Abstract BackgroundEpidemiologists need tools to measure effects of gender, a complex concept originating in the humanities and social sciences which is not easily operationalized in the discipline. MethodsWe conducted a conceptual analysis and applied causal and mediation analysis methodology to standard questions in order to propose a methodologically appropriate strategy for measuring sex and gender effects in health.ResultsWe define gender as a set of norms prescribed to individuals according to their attributed-at-birth sex. Gender pressure creates a systemic gap, at population level, in behaviors, activities, experiences, etc. between men and women. A pragmatic individual measure of gender would correspond to the level at which an individual complies with a set of elements constituting femininity or masculinity in a given population, place and time. However, defining and measuring gender is not sufficient to isolate the effects of sex and gender on a health outcome. We should also think in terms of pathways to define appropriate analysis strategies. Gender could also be examined as a mechanism rather than through its realization in the individual, by considering it as an interaction between sex and environment. ConclusionsBoth analytical strategies have limitations relative to the impossibility of reducing a complex concept to a single or a few measures, and of capturing the entire effect of the phenomenon. However, these strategies could lead to more accurate and rigorous analyses of the mechanisms underlying health differences between men and women, and ultimately limit the sex and/or gender bias encountered in epidemiological and clinical research studies.

2020 ◽  
Vol 4 ◽  
pp. 247028972098001
Author(s):  
Rebecca Leeds ◽  
Ari Shechter ◽  
Carmela Alcantara ◽  
Brooke Aggarwal ◽  
John Usseglio ◽  
...  

Sex differences in cardiovascular disease (CVD) mortality have been attributed to differences in pathophysiology between men and women and to disparities in CVD management that disproportionately affect women compared to men. Similarly, there has been investigation of differences in the prevalence and presentation of insomnia attributable to sex. Few studies have examined how sex and insomnia interact to influence CVD outcomes, however. In this review, we summarize the literature on sex-specific differences in the prevalence and presentation of insomnia as well as existing research regarding the relationship between insomnia and CVD outcomes as it pertains to sex. Research to date indicate that women are more likely to have insomnia than men, and there appear to be differential associations in the relation between insomnia and CVD by sex. We posit potential mechanisms of the relationship between sex, insomnia and CVD, discuss gaps in the existing literature, and provide commentary on future research needed in this area. Unraveling the complex relations between sex, insomnia, and CVD may help to explain sex-specific differences in CVD, and identify sex-specific strategies for promotion of cardiovascular health. Throughout this review, terms “men” and “women” are used as they are in the source literature, which does not differentiate between sex and gender. The implications of this are also discussed.


2007 ◽  
Vol 12 (1) ◽  
pp. 75-89 ◽  
Author(s):  
Stephen Whittle ◽  
Lewis Turner

Gender transformations are normatively understood as somatic, based on surgical reassignment, where the sexed body is aligned with the gender identity of the individual through genital surgery – hence the common lexicon ‘sex change surgery’. We suggest that the UK Gender Recognition Act 2004 challenges what constitutes a ‘sex change’ through the Act's definitions and also the conditions within which legal ‘recognition’ is permitted. The sex/gender distinction, (where sex normatively refers to the sexed body, and gender, to social identity) is demobilised both literally and legally. This paper discusses the history of medico-socio-legal definitions of sex have been developed through decision making processes when courts have been faced with people with gender variance and, in particular, the implications of the Gender Recognition Act for our contemporary legal understanding of sex. We ask, and attempt to answer, has ‘sex’ changed?


2016 ◽  
Vol 3 (1) ◽  
pp. 56-79
Author(s):  
Samantha Sommer Miller ◽  
Glenn Miles ◽  
James Havey

Research on prostitution and trafficking has largely focused on the exploitation of girls and young women. This research comes out of the “Listening to the Demand” two-part study by an independent research team on the sex industry in Phnom Penh, Cambodia. “Listening to the Demand” is a series of research exploring often over-looked populations in the anti-trafficking conversation, including men and transgender people. The first of the studies was completed in 2013 and focuses on men who purchased sex with female sex workers. Interviews of 50 Cambodian and 50 foreign heterosexual and bisexual males explored the respondents’ views and use of prostituted women in Southeast Asia’s sex industry. The second part of the research was completed in 2014 and focuses on men who purchase sex with men. In this second part of the project, 51 Cambodian and 23 foreign men who have sex with men were interviewed about their views of prostitution, the individual sex worker, and their experiences of Cambodia’s sex industry. Due to its comparative nature, the research seeks to deliver information on the differences in culture between the foreign and Cambodian men who seek to pay for sexual services. Results point to the need for proper sex and gender education as well as different approaches when planning projects to reach out to men purchasing sex. In gaining a deeper knowledge of the beliefs and behaviours among the demand population, the findings suggest more holistic approaches are needed to combat the exploitation of sexual services in Cambodia.



2021 ◽  
Vol 11 (1) ◽  
Author(s):  
José Hernández-Orallo ◽  
Bao Sheng Loe ◽  
Lucy Cheke ◽  
Fernando Martínez-Plumed ◽  
Seán Ó hÉigeartaigh

AbstractSuccess in all sorts of situations is the most classical interpretation of general intelligence. Under limited resources, however, the capability of an agent must necessarily be limited too, and generality needs to be understood as comprehensive performance up to a level of difficulty. The degree of generality then refers to the way an agent’s capability is distributed as a function of task difficulty. This dissects the notion of general intelligence into two non-populational measures, generality and capability, which we apply to individuals and groups of humans, other animals and AI systems, on several cognitive and perceptual tests. Our results indicate that generality and capability can decouple at the individual level: very specialised agents can show high capability and vice versa. The metrics also decouple at the population level, and we rarely see diminishing returns in generality for those groups of high capability. We relate the individual measure of generality to traditional notions of general intelligence and cognitive efficiency in humans, collectives, non-human animals and machines. The choice of the difficulty function now plays a prominent role in this new conception of generality, which brings a quantitative tool for shedding light on long-standing questions about the evolution of general intelligence and the evaluation of progress in Artificial General Intelligence.


2018 ◽  
Vol 28 (11) ◽  
pp. 1769-1787 ◽  
Author(s):  
Ann Kristin Bjørnnes ◽  
Monica Parry ◽  
Marit Leegaard ◽  
Ana Patricia Ayala ◽  
Erica Lenton ◽  
...  

Symptom recognition and self-management is instrumental in reducing the number of deaths related to coronary artery disease (CAD) in women. The purpose of this study was to synthesize qualitative research evidence on the self-management of cardiac pain and associated symptoms in women. Seven databases were systematically searched, and the concepts of the Individual and Family Self-Management Theory were used as the framework for data extraction and analysis. Search strategies yielded 22,402 citations, from which 35 qualitative studies were included in a final meta-summary, comprising data from 769 participants, including 437 (57%) women. The available literature focused cardiac pain self-management from a binary sex and gender perspective. Ethnicity was indicated in 19 (54%) studies. Results support individualized intervention strategies that promote goal setting and action planning, management of physical and emotional responses, and social facilitation provided through social support.


Author(s):  
Shana D Stites ◽  
Hannah Cao ◽  
Kristin Harkins ◽  
Jason D Flatt

Abstract Objective Differences between men and women are common in published research on aging and Alzheimer’s disease and Alzheimer’s disease and related dementias (AD/ADRD). What do these differences mean? To answer this, rigorous measurement is needed. We investigated current methods for measuring sex/gender in aging and AD/ADRD cohort studies. Method An online survey was sent to NIA-funded Alzheimer’s Disease Research Centers (ADRCs) (n=38) and investigator-initiated cohort studies (n=38) to assess practices around enrollment of men and women and measurement of sex and gender. Results The response rate was 65.8% (n=50). All enrolled men and all but two investigator-initiated studies enrolled women. Most cohorts (43/50) had no documented definitions for categories of “men” or “women”. Over 85% of cohorts relied solely on self-report questions to capture sex/gender data (n=43/50). Issues with administration were also identified (n=7). Discussion Our findings identify gaps in current approaches used to measure sex and gender in aging and AD/ADRD research. We discuss opportunities to bridge these gaps and advance measurement of sex and gender in aging and AD/ADRD research. Changes are needed to ensure inclusion and representation of sociocultural diversity in research samples, and consistency in data collection in aging and AD/ADRD research.


Author(s):  
Chris Gilleard ◽  
Paul Higgs

This chapter begins by considering the distinction between sex and gender. The latter constitutes the source of the social division between men and women considered as social beings. It serves as both a reflection of division and inequality and a source of difference and identity. The chapter then explores the framing of this division in terms of patriarchy and the inequalities that are organised by and structured within the relations of work and of social reproduction. It focuses next upon the consequences of such a division, first in terms of both financial assets and resources and then in terms of social relational capital, drawing upon Putnam’s distinction between bridging and bonding capital. It then considers other sources of difference that become more salient in later life, in terms of health illness and longevity. The chapter ends with the role of gender in representing later life, and the role of later life in representing gender. It concludes by distinguishing between gender as a structure shaping third age culture, and gender as a constituent in the social imaginary of the fourth age.


ESC CardioMed ◽  
2018 ◽  
pp. 2827-2830
Author(s):  
Eva Prescott

There are well-described differences between men and women in epidemiology, pathophysiology, presentation, and outcome of heart disease. Although risk factors responsible for cardiovascular disease are similar in men and women their relative importance differs. Puzzlingly, women have more angina yet less obstructive coronary artery disease. Also, when they suffer myocardial infarction, women more often present with myocardial infarction with non-obstructed coronary arteries (MINOCA) and takotsubo cardiomyopathy. Women have less systolic heart failure than men but more heart failure with preserved ejection fraction, a condition yet to find evidence-based treatment. Atrial fibrillation is also less common in women than men of similar age, but women with atrial fibrillation have higher risk of stroke than their male counterparts.


2020 ◽  
Vol 28 (12) ◽  
pp. 656-661
Author(s):  
R. Bolijn ◽  
I. Schalkers ◽  
H. L. Tan ◽  
A. E. Kunst ◽  
I. G. M. van Valkengoed

Abstract Background Recently, cardiovascular disease (CVD) research has focused on sex- and gender-related cardiovascular risk factors, in addition to conventional risk factors. This raises the question which factors are perceived by the target group (patients with CVD) as priorities for further research. Methods We carried out a survey to study priority setting for more research into conventional and sex- and gender-related risk factors according to 980 men and women with CVD or those at increased risk of CVD in the Netherlands. Data on conventional and sex- and gender-related risk factors were descriptively analysed, stratified by gender group. Results The most frequently prioritised conventional factors according to men were heritability, overweight and unhealthy diet, while women most frequently listed stress, heritability and hypertension. The most frequently prioritised sex- and gender-related risk factors were depression or depressive feelings, migraine and having many caretaking responsibilities (men), and pregnancy complications, contraceptive pill use and early age at menopause (women). New research on sex- and gender-related risk factors was perceived roughly as relevant as that on conventional factors by men (mean 7.4 and 8.3 on a 1–10 scale, respectively) and women (8.2 and 8.6, respectively). Ethnic and gender minority groups placed more emphasis on risk factors related to sociocultural aspects (gender) than the majority group. Conclusion Men and women with CVD or those at increased risk of CVD perceived new research on conventional and sex- and gender-related risk factors as a priority. These findings may guide researchers and funders in further prioritising new CVD research.


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