scholarly journals Plasma distribution of non-cholesterol sterols precursors of cholesterol synthesis and phytosterols depend on HDL concentration

2020 ◽  
Author(s):  
Valeria Sutti Nunes ◽  
Eliton Juniro Silva ◽  
Guilherme Silva Ferreira ◽  
Sayonara Ivana Santos Assis ◽  
Vanessa Helena de Souza Zago ◽  
...  

Abstract Background Because several sterols are carried by serum lipoproteins that are pivotal in cholesterol metabolism and atherosclerosis this study aimed at investigating their lipoprotein distribution in individuals differing according to HDL-C plasma levels. Methods Healthy participants were selected with plasma HDL-C concentrations < 40 mg/dL (Low HDL, n = 12), above 40 mg/dL and below 60 mg/dL (Controls, n = 10), or above 60 mg/dL (High HDL, n = 15). Plasma lipoproteins were separated by sequential ultracentrifugation. [27-OHC]), noncholesterol sterols precursors of cholesterol synthesis (NCSPCS: desmosterol and lathosterol) and phytosterols (campesterol and sitosterol) were measured by GC-MS analysis. Diferences between groups were compared by Kruskall-walys and Dunn's post-test with correction by Bonferroni. Results The groups were similar in about BMI, age, gender distribution and blood glucose, total cholesterol and LDL-C. The High HDL group had lower concentrations of triglycerides and VLDL-C compared to others. Percentage distribution of plasma 24-OHC and 27-OHC in lipoproteins did not differ among investigated groups, but plasma concentration of 24-OHC was lower in High HDL than in Low HDL (27- OHC significance difference was borderline). NCSPCS and phytosterols predominate in LDL, which carries approximately 50% of these molecules. Approximately 30% of desmosterol and lathosterol are present in HDL, the High HDL group carrying higher percent of both sterols than the Low HDL and Control groups. Less than 20% of NCSPCS are transported in VLDL. Concentration of plasma campesterol and sitosterol did not differ among groups. However, LDL sitosterol percent distribution is lower in High HDL than in Low HDL and Controls. Campesterol and sitosterol percent distributions are higher in High HDL than in the Low HDL group. Conclusions Elevated NCSPCS in the High HDL group suggests HDL facilitates the export of these sterols from cells but not the export of the cholesterol metabolite 24-OHC which is lower in the High HDL than in the Low HDL group. Percent campesterol and sitosterol elevated in HDL suggests phytosterols absorbed in the enterocytes are incorporated mostly into the nascent HDL.

Author(s):  
Hasanul Arifin Zul And Masitowarni Siregar

This thesis is focused on the investigation of the effect of applying animal cartoon pictures on students’ achievement in writing narrative text. This study aims to find whether applying animal cartoon pictures significantly affect the students’ writing achievement or not. The data in this study were obtained by administering a written test. The population was the 2015/2016 first year (grade XI) of SMA Swasta Nusantara Lubuk Pakam and 66 students were taken as the sample by using random sampling. The sample was divided into two groups, experimental and control groups. The experimental group was taught by applying animal cartoon pictures while the control group without animal cartoon pictures (x = lecturing). The data were taken the scores from the pre-test and post-test to both experimental and control groups. These data were analyzed by using t-test. The result of computing the t-test obviously showed that t-observed is higher than t-table (5.21 >1,67) with the degree of freedom 64 (df =N-2) at the level significance 0,05 one tail test. It showed that the application of animal cartoon pictures significantly affected the students of SMA Swasta Nusantara Lubuk Pakam achievement in writing narrative text.


2021 ◽  
Vol 5 (2) ◽  
pp. 773
Author(s):  
Lia Ardiana Safitri

This study was conducted with the aim of knowing the significant role of WhatsApp in teaching vocabulary, especially staff learning achievement which was limited to vocabulary achievement as measured by a vocabulary test at Umbul Ponggok Klaten. Participants in this study amounted to 30 people consisting of 15 men and 15 women. All participants will learn English as a foreign language using WhatsApp to learn new vocabulary items via their mobile, tablet or laptop. Participants' English level will be measured. Random sampling procedure was carried out. To carry out the research, a true experimental design was used. The participants were assigned to two experimental and control groups. The assessment instrument in this study used a pre-test and post-test. The results showed that the use of the WhatsApp application in teaching vocabulary to the Umbul Ponggok Klaten staff was able to improve the achievement of new English vocabulary mastery of the Umbul Ponggok Klaten staff which was getting better.


2017 ◽  
Vol 13 (1) ◽  
pp. 39
Author(s):  
Duriye Esra Angın

The purpose of this research is to investigate the effects of Dora the Explorer cartoon on the spatial concept acquisitions and spatial abilities of the preschool children. The study was carried out with 80, 60-71 month old children attending preschools. Post-test only control group model is used in the research in order to identify the existing phenomena in a controlled manner. “The Bracken Basic Concept Scale, Third Edition: Receptive (BBCSIII:R) Form Direction/Position Subscale” and two different “Spatial Ability Games” were used to assess children’s spatial concept acquisitions and spatial abilities. Independent sample t-test was used in order to compare the average of post-test scores of the children in the experimental and control groups. According to the findings, it is found that there is meaningful difference between scores of post-tests of direction/position subscale and spatial ability games score. Comparing the scores of post-test of direction/position subscale and spatial ability games of experimental and control groups, it was found that there was a meaningful differentiation in favor of experimental group.


2018 ◽  
Vol 7 (2) ◽  
pp. 91-100
Author(s):  
Islam Namazian Doost ◽  
Soheila Tahmasbi

This study aims to investigate the possible effects of peripheral learning on elementary EFL learners’ grammar improvement: the case of prepositions of time and place. Two elementary classes were selected as experimental and control groups. Before beginning the treatment, a grammar test was administered to both the groups as a pre-test. Then, as treatment, the experimental group was exposed to realia, pictures, posters and texts, while the control group was not. After term-long treatment of 10 weeks, the two groups received the same grammar test as post-test. The results of t-test showed that the experimental group improved their grammar ability, i.e., knowledge of prepositions of time and place more than their friends in the control group. The finding of the study may open an optional path for teachers to include some peripheral materials in their teaching environment to further invest on unconscious learning abilities of the students.   Keywords: Peripheral learning, reposition of time, prepositions of place, grammar.


2019 ◽  
Vol 2 (2) ◽  
pp. 269
Author(s):  
Yoga Pratama

The objectives of this study were to find out whether or not there was significant improvement in writing and speaking achievements of the eighth grade students of SMPN1 Jarai after they were taught by using Sociogram, to find out whether or not there was significant improvement in each aspect of writing and speaking achievements of the eighth grade students of SMPN1 Jarai after they were taught by using Sociogram, to find out whether or not there was significant difference in writing and speaking achievements between the eighth grade students of SMP 1 Jarai who were taught by using Sociogram and those who were not, and to find out the perception of the eighth grade students of SMPN 1 Jarai after they were taught by using Socoiogram. In this paper, an experimental research method with pre and post test control group design was used with 70 students as the sample divided into two groups, experimental and control group. However, only the students of the experimental group were taught by using Sociogram. The obtained data were analyzed by using t-test. The students were given questionnaire to know their perceptions. The result showed that there was a significant difference in both students? writing and speaking achievements after they were tought by using Sociogram. Furthermore, it was found that there was a significant difference in students? writing and speaking achievement between the experimental and control groups. In conclusion, Sociogram improves the students? writing and speaking achievements.


2021 ◽  
Vol 1 (2) ◽  
pp. 55-67
Author(s):  
Werna Nontji ◽  
Dwi Kartika Sari ◽  
Sitti Maria Ulfa ◽  
Syafruddin Syarif ◽  
Inez Vravty Lestari ◽  
...  

Background: Educating mothers during their postpartum period could potentially help them to overcome some important phases after giving birth. The process of education is evaluated based on the mothers’ knowledge about their independent self-care. Independency is an activity that is started individually and is done based on self-capability. The independency in the postpartum care is not only important to decrease the mother’s mortality and morbidity rate, but it is also crucial to strengthen and improve the post-partum mother’s healthy behavior during the perineal care. Providing education using Android-based application called BUBI Care could be potential to facilitate a more dynamic transfer of knowledge to the postpartum mothers.Aims: To analyze the knowledge, skills, and independence of primipara postpartum mothers in independent perineal care before and after accessing BUBI Care app. Research Method: employing quasi experimental research with pre-test and post-test design with control group design. The sample for this research were 19 pregnant mothers TM III (pregnancy age of ? 38 weeks) on each group. The treatment group was educated using BUBI Care Android app that was conducted at one of Public Health Center. The control group was educated without BUBI Care that was conducted at a Midwife Practice Clinic. The research was conducted on September to October 2020. Study Result: According to the Wilcoxon test, there was a difference in the pre-test knowledge of the treatment and control groups with the similar median of 53 and p-value of 0.666, the treatment group showed their scores improved to 80 on the post-test while the control group stayed at 53 with the p-value of 0.000. It means that BUBI Care app education influences the post-test. On the other hand, the perineal care skill saw a difference between the intervention and control groups. The intervention group had a mean of 70.05 and 56.68 for the control group with the p-value of 0.002 which means that there was an influence from the BUBI Care app education. Additionally, Mann Whitney test showed that the intervention group had a mean score of 78.95, but the control group only had 49.26, the total difference between the two are 29.69 with the p-value of 0.000. It can be concluded that there is a significance in difference in the independency rate from the provision of BUBI Care Android app education.Conclusion:  there is a significance effect on the intervention group in terms of Android based usage.


2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Salmauwati Salmauwati ◽  
Muhamad Agus Wibowo ◽  
Dedeh Kurniasih

ABSTRACTThis study was initiated by the students’ low learning outcomes on Chemistry subject and the teachers’ preference in using lecture method in teaching learning process.This study aimed at 1) finding out the differences of students’ learning outcomes between the use of flash media-assisted practical method and lecture method on hydrocarbon class at grade XI MIA of SMA Muhammadiyah I Pontianak. Using quasi experimental design and Control Group Posttes Design, this study employed the students of grade XI MIA 2 as the samples of experiment group, andthe students of grade XI MIA 2 as the samples of control group. The data collection techniques used were measurement and observation. While the instruments employed were observation sheet and essay. TheU-Mann Whitneytest revealed that the post test score of 0,0140< 0,05 Ho was rejected, while the Ha one was accepted. It means that there was correlation of students’ learning outcomes between the experiment and the control groups. In addition, the effect size result was 1,086 > 0,8 and considered high which indicated the positive effect of flash media-assisted practical method in enhancing students’ learning achievement.Keywords: flash, learning outcomes, hydrocarbon, practical method


Author(s):  
Rafi’ah Nur ◽  
Rifka Annisa

Vocabulary is the basic aspect of language. The ability to master vocabulary holds an important part in learning a language, including English. That becomes one of the researcher's considerations to conduct this research when observing at one of Indonesia's high schools since the students show difficulties in vocabulary mastery. Modifying the teaching media can become a problem solving for students' lack of vocabulary mastery. In this case, using Rosetta Stone CALL software is suggested to overcome the problem. The research's objective was to determine whether or not the use of Rosetta Stone CALL software can improve the tenth-grade students' vocabulary mastery. The researcher applied a quasi-experimental method, with two group pre-test and post-test design. The research sample was forty students from two classes taken from the population of the 10th-grade students of SMA Negeri 2 Barru. The data analysis result showed that the pre-test's mean score in the experimental class was 2.21, and the post-test was 3.04. It proves that the tenth-grade students' vocabulary mastery improved using Rosetta Stone CALL Software. After analyzing the data using SPSS version 21, the probability value in the post-test was 0.01, and the significance value was 0.05. It means that the probability value (0.01) was lower than the significance value (0.05). It was indicated that H0 was rejected and H1 was accepted. It revealed that the vocabulary mastery of the tenth-grade students of SMA Negeri 2 Barru for the experimental and control groups was significantly different.


2019 ◽  
Vol 3 (2) ◽  
pp. 66
Author(s):  
Yova Tri Yolanda ◽  
Muhana Sofiati Utami

Purpose of this research is to validated the module Client Facilitating Training to increase social worker knowledge about stress  and skill for facilitating client. Training included psychoeducation about stress and management stress, basic of client facilitating method and communication skill in facilitating process. Subjects of this research are 12 social worker and divided to experiment and control group. This research using quasi experiment with non control group design with pretest and post test sample. Data collected by management stres questionnaire, facilitating scale and field data collected by observer and supervisor. Results indicated that there is a significant differences between experiment and control groups in stress and management stress (Z=-3,017; p<0,05) with large effect size of 0,87 and Facilitatting skill (Z= -1,354; p<0,05) with large effect size of 0,84. Client Facilitating Training is valid to improve social worker knowledge stress  and management stress  and facilitating skill.


2018 ◽  
Vol 4 (1) ◽  
pp. 17-23
Author(s):  
Dewi Rabiola ◽  
Muhammad Andi Setiawan

This study aims to determine whether there is a difference in understanding of Student Polite regarding the provision of Group Guidance Services based on the Dandang Tingang Philosophy. This study used the Pure Experimental Research approach. The design used is the pretest-posttest control group design. Based on the results of research conducted at Palangka Raya Muhammadiyah Middle School with the results of the calculation of paired sample test with t count on the results of the Pre-test the value of t = 1,088 = and t table 2,10 which shows no difference between the control group and the experimental and postal results -test value t = 5.696 = and t table 2.10 price t count = t table so that Ho is rejected, and Ha is accepted it can be said if the experimental group gets better results compared to the control group. In the results of the Pre-test which showed no difference between the experimental and control groups and after being given treatment through group guidance services in the experimental group, the results of the post-test showed there were differences between the control and experimental groups. It can be concluded if the implementation of group guidance services in the experimental class is effective in increasing the understanding of students manners.


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