scholarly journals Parental Experiences Before and After Dialogical Family Guidance in Families With a Child With Neurodevelopmental Disorders

2021 ◽  
Author(s):  
Diana Cavonius-Rintahaka ◽  
Mervi Roos ◽  
Christopher Gillberg ◽  
Eva Billstedt ◽  
Anna Liisa Aho
Keyword(s):  
Family Support ◽  
Neurodevelopmental Disorders ◽  
Daily Life ◽  
Intervention Group ◽  
Family Health ◽  
Family Intervention ◽  
Group I ◽  
Group Ii ◽  
The Relationship ◽  
Family Functionality

Abstract Background: Previous studies have highlighted the need to offer targeted effective interventions to strengthen the wellbeing of all family members in families with children with neurodevelopmental disorders (NDD). Interventions for this target group requires development and research. The purpose of this study was to test a new family intervention (Dialogical Family Guidance / DFG).Method: Fifty families of children with NDD took part in this study. Families were randomized into two groups. Families in Intervention group I were delivered DFG immediately, and families in Intervention group II were delivered DFG after three months. Family functionality, health and support (FAFHES) and DFG intervention parent questionnaires were used to collect data at baseline, and after three and six months. Thirty-four families completed the whole protocol.Results: Intervention group I experienced better family health and family support after DFG compared to baseline, and the experience of increased support remained at the three month follow-up. Intervention group II also experienced better family support after three months compared to baseline, although they were still waiting for DFG to initiate. Intervention group II continued to increase the experience of support throughout DFG. The positive changes were statistically significant concerning the experience of social support.Managing as a parent in daily life and the relationship between parents were associated with family functionality and family health. Most parents` reported that DFG had helped them manage better with their child with NDD, and that they would recommend DFG to other families.Conclusion: The study findings suggest that the DFG intervention may strengthen parent experiences of family support. Managing as a parent in daily life and the relationship between parents was associated with family functionality and family health. DFG parent questionnaire inform that practical guidance, psychoeducation, dialogue with the staff and positive feedback for own parenthood are strengthening factors. Delivering DFG as a family intervention implemented by healthcare staff can be recommended as an additional type of support for families with a child with NDD.Trial registration: ClinicalTrials.gov NCT04892992 (retrospective registered)

scholarly journals Randomized Clinical Trial Comparing Dialogical Family Guidance with Ordinary Clinical Treatment for Families with a Child with Neurodevelopmental Disorders

2021 ◽  
Author(s):  
Diana Cavonius-Rintahaka ◽  
Mervi Roos ◽  
Christopher Gillberg ◽  
Eva Billstedt ◽  
Anna Liisa Aho
Keyword(s):  
Social Support ◽  
Family Functioning ◽  
Neurodevelopmental Disorders ◽  
Daily Life ◽  
Intervention Group ◽  
Family Health ◽  
Clinical Treatment ◽  
Control Group ◽  
Analytical Strategy ◽  
Targeted Interventions

Abstract Objectives Previous studies have highlighted the need to offer targeted interventions to strengthen the wellbeing of family members in families with children with neurodevelopmental disorders (NDD). Interventions for this target group require research and development. The purpose of this study was to test a new family intervention: Dialogical Family Guidance (DFG). Methods Families of children with NDD were randomized into an intervention group that was delivered DFG and a comparison group provided with ordinary clinical treatment. The Family Functioning, Family Health and Social Support (FAFHES) and the DFG instrument were used to collect data at baseline and after 3 months. Repeated measure analysis of variance (ANOVA) was used as an analytical strategy. Results There was a significant within-subjects effect of time on family health and social support, indicating that family health and social support increased in both groups over time. There was also a significant between-subjects effect of group and interaction between time and group on social support, indicating that social support increased more in the intervention group than in the control group. Managing in daily life and the relationship between parents were associated with family functioning and family health. Conclusion DFG can strengthen parental experiences of social support. Managing in daily life, relationship between parents, practical guidance, psychoeducation, dialogue, and receiving positive feedback on parenting were strengthening factors during DFG. However, the results of this study must be considered as only preliminary, as they relate only to parental perceptions of the intervention effects. Trial registration ClinicalTrials.gov NCT04892992 (retrospectively registered).

scholarly journals The relationship of the prolonged PR interval with the long-term survival in patients with heart failure undergoing cardiac resynchronization therapy

2020 ◽  
Vol 25 (1) ◽  
pp. 33-38
Author(s):  
A. M. Soldatova ◽  
V. A. Kuznetsov ◽  
T. P. Gizatulina ◽  
L. M. Malishevsky ◽  
S. M. Dyachkov
Keyword(s):  
Cardiac Resynchronization ◽  
Rank Test ◽  
Term Survival ◽  
Log Rank Test ◽  
Group I ◽  
Pr Interval ◽  
Qrs Duration ◽  
Group Ii ◽  
The Relationship

Aim. To assess the relationship between the prolonged PR interval (≥200 ms) and the long-term survival of patients undergoing cardiac resynchronization therapy (CRT).Material and methods. A total of 85 patients (mean age — 55,1Ѓ}9,9 years; men — 81,2%) with NYHA class II-IV heart failure (HF) were examined. The mean follow-up was 34,0Ѓ}21,2 months. Patients with PR<200 ms (n=52) made up group I, with PR≥200 ms (n=33) — group II. Then the patients were divided into subgroups depending on the QRS duration: ≥150 ms (n=33 in group I and n=14 in group II, respectively) <150 ms (n=19 in group I and n=19 in group II, respectively).Results. In patients of group II, a history of myocardial infarction (MI) was more often registered (p=0,005), left ventricular ejection fraction (LVEF) was lower (p=0,032). In a multivariate analysis, MI (OR 3,217; CI 95% 1,188-8,712; p=0,022) and LVEF value (OR 0,869; CI 95% 0,780-0,968; p=0,011) had a significant relationship with the PR interval prolongation (≥200 ms). The survival of patients of group I was 59,6%, group II — 18,2% (Log-rank test p<0,001). According to Cox regression model, the initial left ventricle end-systolic volume (OR 1,012; 95% CI 1,006-1,017; p<0,001), inferior wall MI (OR 1,690; 95% CI 1,131-2,527; p=0,011) and PR interval ≥200 ms (OR 2,179; 95% CI 1,213–3,915; p=0,009) were associated with long-term mortality. In patients with PR≥200 ms, survival rate was low, regardless of the QRS duration (21,4% in patients with QRS≥150 ms, 15,8% in patients with QRS<150 ms; Log-rank test p=0,698) In patients with PR<200 ms, the survival rate of patients with QRS≥150 ms was 72,7%, and for patients with QRS<150 ms — 36,8% (Log-rank test p=0,031).Conclusion. In HF patients, PR interval prolongation (≥200 ms) is associated with long-term mortality increase. The highest survival rates were observed in patients with PR<200 ms and QRS≥150 ms. In patients with QRS≥150 ms, the presence of PR≥200 ms should be considered as an additional criterion for CRT.

Changes in Teat Morphology (Doka Phenomenon) and Estrus Prediction in Riverine Buffaloes (Bubalus bubalis)

2019 ◽  
Author(s):  
S K Joshi ◽  
T K Mohanty ◽  
A Kumaresan ◽  
M Bhakat ◽  
S Sathapathy
Keyword(s):  
Morphological Changes ◽  
Bubalus Bubalis ◽  
North India ◽  
Research Centre ◽  
Murrah Buffaloes ◽  
Group I ◽  
Before And After ◽  
Group Ii ◽  
The Difference ◽  
The Relationship

The objective of the study was to characterize the term Doka and to capture morphological changes in teat to find out the relationship between Doka and onset of estrus in Murrah buffaloes (Bubalus bubalis). The Murrah buffaloes maintained at of Livestock Research Centre (LRC), ICAR-NDRI, Karnal were classified into two groups based on the lactation number for the study of Doka characteristics. In group I, twenty animals up to 3rd lactation were incorporated, whereas thirty animals from 4th to 5th lactation were included in group II. The period when buffaloes showed teat engorgement was called as Doka period, is the local term used by the farmers in North India that can be taken as a visual sign for prediction of estrus. The length and diameter of teats, before and after milking were measured, for both the groups during morning and evening milking and subsequently analyzed. The present study confirmed that the teat diameter (mm) before milking during Doka was significantly (plessthan0.05) higher as compared to pre Doka period in both the groups (group-I - 37.01 ±2.13 vs 28.42 ±1.64, group-II - 53.49 ±2.82 vs 41.096±2.16). The teat diameter (mm) during Doka period after milking was significantly (plessthan0.05) more in both the groups (group-I - 26.65 ±1.26 vs 24.44 ±1.16, group-II - 39.27 ±2.41 vs 35.31 ±2.17) as compared to pre Doka period. So, it can be concluded that the changes in teat diameter can safely be considered as a sign of Doka and the forthcoming heat in Murrah buffaloes. However, the difference in teat length between different stages of Doka was found to be non significant.

Active and inactive renin in primary and secondary adrenal insufficiency and during ACTH infusion

1983 ◽  
Vol 102 (2) ◽  
pp. 265-270
Author(s):  
Lutz Belkien ◽  
Petra Exner ◽  
Wolfgang Oelkers
Keyword(s):  
Plasma Renin ◽  
Renal Secretion ◽  
Young Males ◽  
Active Renin ◽  
Group I ◽  
Inactive Renin ◽  
Group Ii ◽  
Peripheral Activation ◽  
The Relationship ◽  
Stimulation Of

Abstract. Prolonged low-dose ACTH infusion leads to a transient stimulation of plasma renin activity (PRA) and angiotensin II. In part 1 of the present study (infusion of 10 IU of ACTH per day for 38 h into 6 normal young males), it was shown that the concentration of active renin (aPRC) increases in parallel to PRA. Thus, the rise in PRA is either due to net active renin secretion by the kidney or to increased conversion of inactive into active renin. Since the plasma concentration of inactive renin (iPRC) tended to rise rather than to fall during ACTH infusion, peripheral activation of inactive renin is probably not the cause of the rise in aPRC. Part 2 of the study consisted in the measurement of plasma ACTH, cortisol, PRA, aPRC and iPRC in 10 patients (group I) with primary adrenocortical insufficiency (8 Addisonians, 2 adrenalectomized Cushing's) and in 9 patients with hypopituitarism (group II) after short-term withdrawal of hydrocortisone substition therapy. ACTH was 1770 ± 390 pg/ml in the former and 20 ± 4 pg/ml in the latter group. PRA and aPRC were higher and the ratio iPRC:aPRC lower in group I than in group II. This might indicate stimulation of active renin formation by ACTH. However, it is unlikely that the higher aPRC levels in group I are due to increased peripheral activation of inactive renin, since the relationship between aPRC and the ratio iPRC:aPRC fell on the same curve in both groups. ACTH or an ACTH-dependent mechanism raises aPRC, probably by stimulating its renal secretion rather than by peripheral activation of inactive renin.

scholarly journals Effectiveness of the Elderly Caring Model as an Intervention to Prevent the Neglect of the Elderly in the Family

2019 ◽  
Vol 7 (14) ◽  
pp. 2365-2370
Author(s):  
Ezalina Ezalina ◽  
Rizanda Machmud ◽  
Nusyrwan Effendi ◽  
Yantri Maputra
Keyword(s):  
Older People ◽  
Family Support ◽  
Social Relations ◽  
Intervention Group ◽  
Family Health ◽  
The Elderly ◽  
Control Group ◽  
P Value ◽  
Social Activities ◽  
The Family

BACKGROUND: The increasing number of older people is racing against diseases and problems that accompany the elderly, so it is very important to check the care of the elderly. Family concern as a caregiver is needed in carrying out care for the elderly to ensure that the elderly are not neglected. AIM: The study aims to determine the effectiveness of the elderly caring model as an intervention to prevent the neglect of the elderly in the family. MATERIAL AND METHODS: The quasi-experimental design with the pre-control group non-equivalent test post-test was the provision of training in the elderly caring model by comparing 2 groups namely the intervention group using the module and control group without using the module. The sample is a family that has an elderly (age ≥ 60 years) who are the main caregivers of the elderly with a total of 50 people each for each group taken by multistage cluster sampling. Data collection through questionnaires to determine the variables of family older people about family support, family health assignments, social relations, and elderly social activities and preventive behavior of elderly neglect. Data analysis used the independent sample t-test and general linear model report measure (GLM-RM) test for repeated measurements. RESULTS: The results showed that there was an influence of the caring elderly model on increasing family support in the elderly, increasing family health duties on the elderly towards increasing social relations and social activities in the elderly and neglecting the neglect behaviour of the elderly in the family (p-value = 0,000). Improve the behaviour of preventing neglect of the elderly in the family compared to groups that do not use modules where the value of p = 0,000. CONCLUSION: It can be concluded that the elderly caring model effectively prevents my employees from neglecting the elderly in the family.

scholarly journals The Relationship Between Dental Caries and YKL-40 Levels in Saliva

2020 ◽  
Author(s):  
Gülsüm Duruk ◽  
Esra Laloglu
Keyword(s):  
Dental Caries ◽  
Group Iii ◽  
Group I ◽  
Pufa Index ◽  
Icdas Ii ◽  
Significant Difference ◽  
Group Ii ◽  
And Gender ◽  
Post Hoc ◽  
The Relationship

Abstract Objective : YKL-40, a new biomarker of localized inflammation, is secreted by macrophages and regulates inflammation and immune responses. The aim of this study was to investigate YKL-40 levels in saliva and compare the level of this mediator in healthy and unhealthy oral cavity. Methods: 85 children (46 girls, 39 boys), aged 6-15 (mean±SD: 9.15±2.16) were included in this study. The children were divided into three groups: Group-I (control, n=25, DMFT/dmft=0), Group-II (n=30, exist of localized dental caries) and Group-III (n=30, exist of localized advanced dental caries). Gingival index (GI), plaque index (PI), DMFT/dmft, DMFS/dmfs, and the number of advanced dental caries according to the ICDAS II and PUFA/pufa index were recorded. Saliva was collected and YKL-40 concentrations were measured. One-way ANOVA with Tukey post hoc, Kruskal-Wallis, multiple regression analysis, and Sperman’s correlation tests were used for statistical analysis. Results: The highest level of YKL-40 was obtained in group III , followed by groups II and I , respectively (p<0.01). In Group II, DMFT/dmft scores and the number of caries (DT/dt) were higher than in group III (p<0.01). In group III, there was a statistically significant correlation between YKL-40 levels in saliva and the number of advanced dental caries. In addition, there was no statistically significant difference in terms of age and gender (p>0.05). Conclusion: Advanced dental caries, rather than DMFT/dmft score, may play an important role in the increasing levels of YKL-40 in saliva.

scholarly journals Study on the relationship between menopausal age, body mass index and total number of teeth

2021 ◽  
Vol 67 (1) ◽  
pp. 29-34
Author(s):  
Ioana Madalina Lescai ◽  
◽  
Laurenta Lelia Mihai ◽  
Monica Mihaela Cirstoiu ◽  
◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
The Body ◽  
Entire Group ◽  
Number Of Teeth ◽  
Group I ◽  
Average Body Mass ◽  
Group Ii ◽  
The Relationship ◽  
Average Body

Objectives. The objective of this study is to assess the state of oral health, from the perspective of the number of teeth present, according to the body mass index as a representative element of health. Materials and methods. This study consists of 180 patients from a private dental practice. All 180 patient records were reviewed for an assessment of the number of teeth present and the body mass index at menopausal age. The cohort of patients was divided into two groups, a group of women aged 40 to 54.9 years and the second group, which included women aged 55 and over. The 2 groups were divided based on premenopausal (group I) and postmenopausal (group II) age. Results. The average number of present teeth (based on radiographs) for the entire population of 180 patients is 22.02 teeth. In group I, for the 109 women in the premenopausal group, the average number of teeth is 23.94. The total number of teeth for the 71 women in the postmenopausal group is 19.07. The average BMI for the entire group of patients is 27.24 kg/m2, with a lower value in group I, 26.25 kg/m2, compared to group II, 28.78 kg/m2. Discussions. The average number of teeth in the premenopausal group is higher than in the postmenopausal group. The average body mass index places the whole series of patients in the overweight category. Conclusions. This study shows that the relationship between BMI and the number of lost teeth is positive and proportional, BMI increases with increasing number of teeth lost at premenopausal age.

Out Come of Expectant Management and Induction of Labour with Premature Rupture of Membrane in Term Pregnancy

2020 ◽  
Vol 11 (1) ◽  
pp. 59-65
Author(s):  
Fazle Noor E Tawhida ◽  
Tabassum Ghani ◽  
Noorjahan ◽  
Shamima Akhter ◽  
Mst Noorjahan Begum
Keyword(s):  
Intervention Group ◽  
Expectant Management ◽  
Neonatal Infection ◽  
Labour Pain ◽  
Time Interval ◽  
Medical College ◽  
Group I ◽  
Oxytocin Infusion ◽  
The Mean ◽  
Group Ii

Introduction: Overall, at least 50% of mothers with PROM near term deliver within 48 hours. The latency period is in general inversely related to the gestational age at the time of PROM. At term, labor is desirable since infections become more likely with more prolong intervals between rupture and delivery. Neonatal complications and perinatal mortality and morbidity also associated with PROM. Material and methods: This randomized clinical trial study was carried out in the Department of Obstetrics and Gynecology Sir Salimuilah Medical College and Mitford Hospital Dhaka, during the period of January 2008 to September 2008. A total of 100 patients with term pregnancy had single fetus and cephalic presentation with PROM were enrolled in this study. After taking informed consent she was randomized in one of the two either groups according to the results of lottery. Fifty in Group I- Termination of the pregnancy (intervention group) by induction of labour and another 50 were in Group II- Expectant management for spontaneous delivery (expectant group). Randomization was 1:1 for intervention and expectant management. Proper history including demographic, past obstetric and medical history was taken, maternal temperature and Fetal heart rate was recorded. Antibiotics were given to all PROM women. The women of intervention group were induced by following ways -Women with riped cervix with oxytocin infusion and with unripe cervix, first underwent ripening by misoprostol followed by oxytocin infusion. Data was collected by standard questionnaire; results were compiled and relevant statistical calculation was done using computer-based software (SPSS). Results: The mean age was 20-24 years were predominant in both groups. Low income patients were more common in both groups. Primigravida were predominant in both groups. The mean gestation age was almost similar in both groups, no significant (p>0.05) difference was found between two groups. Majority (80%) patients had time interval 1 to 12 hours between rupture membrane and onset of labour pain in group I. On the other hand 80% patients in group II had 12 to 24 hours time interval for onset of labour pain after rupture membrane.Normal vaginal delivery was higher in group I, whereas caesarean section (LSCS) was higher group II. No statistically significant (p>0.05) difference was found between two groups.Duration of time interval between on set of labour pain to delivery was <12 hours in group I 88.0% patients and 96.0% in group II respectively. No statistically significant (p>0.05) difference was found between two groups.Hundred percent cases was live birth in both groups. Neonatal infection and death were significantly (p<0.05) higher in group II. Puerperal sepsis was significantly (p<0.05) higher in group II.The mean duration of hospital stay was 4.1±2.2 and 5.1±3.7 days in group I and group II respectively but this was not significant (p>0.05). Conclusion: In the present study there was no statistical difference in the mode of delivery and time interval between onset of labour pain and delivery in two groups though maternal complications, neonatal infection and perinatal death was higher where expectant management was followed. Anwer Khan Modern Medical College Journal Vol. 11, No. 1: Jan 2020, P 59-65

scholarly journals Universal iron supplementation: a simple and effective strategy to reduce anaemia among low-income, postpartum women

2011 ◽  
Vol 15 (3) ◽  
pp. 546-553 ◽  
Author(s):  
Amal K Mitra ◽  
Amal J Khoury
Keyword(s):  
Low Income ◽  
Intervention Group ◽  
Study Groups ◽  
Outcome Variable ◽  
Categorical Variables ◽  
Postpartum Women ◽  
Continuous Variables ◽  
High Risk Women ◽  
Group I ◽  
Group Ii

AbstractObjectiveTo reduce prevalence of anaemia in low-income postpartum women.DesignA randomised, non-blind clinical trial was conducted among 959 low-income, postpartum women in eleven clinics in Mississippi. The clinics were randomised to one of three treatment groups: (i) selective anaemia screening of high-risk women as recommended currently (control); (ii) universal anaemia screening and treatment of anaemic women (group I); and (iii) universal Fe supplementation of 65 mg/d for two months to all low-income women (group II). All study participants within each clinic received the same treatment. Women were followed up at 6 months after delivery. Hb was measured at baseline and at follow-up. The primary outcome variable was the proportion of women with anaemia after treatment.SettingEleven health clinics in Mississippi.SubjectsLow-income, postpartum women.ResultsBaseline characteristics of the three study groups were compared using one-way ANOVA and an appropriate post hoc test for continuous variables and the χ2 test for categorical variables. Fifty-two per cent of postpartum women were anaemic (Hb < 12·0 g/dl) and the rate decreased to 33 % at 6 months after the intervention. Group II women, who received universal Fe supplementation, improved their Hb status significantly (P < 0·001) at 6 months postpartum compared with the other groups. Prevalence of anaemia was also significantly lower among group II women (22·5 %) compared with controls (34 %) and group I women (43 %; P < 0·001).ConclusionsA universal Fe supplementation strategy was effective in reducing the prevalence of anaemia among low-income postpartum women.

scholarly journals Cytoplasmic Incompatibility and Sperm Cyst Infection in Different Drosophila-Wolbachia Associations

Genetics ◽  
2003 ◽  
Vol 164 (2) ◽  
pp. 545-552 ◽  
Author(s):  
Zoe Veneti ◽  
Michael E Clark ◽  
Sofia Zabalou ◽  
Timothy L Karr ◽  
Charalambos Savakis ◽  
...  
Keyword(s):  
Cytoplasmic Incompatibility ◽  
Nematode Species ◽  
Wolbachia Infection ◽  
Host Interactions ◽  
Group I ◽  
Early Embryos ◽  
Wide Range ◽  
Group Ii ◽  
Female Germline ◽  
The Relationship

AbstractWolbachia are a group of maternally transmitted obligatory intracellular α-proteobacteria that infect a wide range of arthropod and nematode species. Wolbachia infection in Drosophila in most cases is associated with the induction of cytoplasmic incompatibility (CI), manifested as embryonic lethality of offspring in a cross between infected males and uninfected females. While the molecular basis of CI is still unknown, it has been suggested that two bacterial functions are involved: mod (for modification) modifies the sperm during spermatogenesis and resc (for rescue) acts in the female germline and/or in early embryos, neutralizing the modification. There is considerable variation in the level of incompatibility in different Wolbachia/host interactions. We examine the relationship between the levels of CI in a number of naturally infected and transinfected Drosophila hosts and the percentage of Wolbachia-infected sperm cysts. Our results indicate the presence of two main groups of Drosophila-Wolbachia associations: group I, which exhibits a positive correlation between CI levels and the percentage of infected sperm cysts (mod+ phenotype), and group II, which does not express CI (mod– phenotype) irrespective of the infection status of the sperm cysts. Group II can be further divided into two subgroups: The first one contains associations with high numbers of heavily Wolbachia-infected sperm cysts while in the second one, Wolbachia is rarely detected in sperm cysts, being mostly present in somatic cells. We conclude that there are three requirements for the expression of CI in a host-Wolbachia association: (a) Wolbachia has to be able to modify sperm (mod+ genotype), (b) Wolbachia has to infect sperm cysts, and (c) Wolbachia has to be harbored by a permissive host.

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