ASSOCIATION OF BLOOD GROUPS OF THE AB0 SYSTEM WITH HEPATITIS C VIRUS INFECTION

Hepatitis C is a viral liver disease caused by HCV. Worldwide, 71 million people suffer from chronic hepatitis C infection. There is a discussion in the literature sources about the association of blood groups of the AB0 system with viral hepatitis; however, the data obtained in different populations of high rank is controversial. The aim of the study was to investigate possible associations of blood groups of the AB0 system with hepatitis C in the Odessa region. The case-control study was conducted in 2017–2019 at the blood transfusion station of SE «Odessa Railway». The control group consisted of 18 963 healthy individuals, the experimental group consisted of 520 people from the donors examined, in which blood antibodies to HCV were detected. Determination of blood groups was performed according to the standard method, serological studies – ELISA on ELISA analyzer III. The analysis using the χ2 criterion showed that the frequencies of blood groups in the control and experimental groups differed significantly (p ≤ 0.005). To determine the effects of each blood group, relative risk frequencies for each blood group were calculated. People with the AB blood group had the lowest risk of infection (OR = 0.60), with a slightly weaker negative association observed among people with blood group 0 (OR = 0.86). Individuals with blood groups A and B had a positive association; the rate of infection of persons with blood group B was the highest (OR = 1.23). The findings complement a diverse picture of such associations in different populations. The variation in associations in different populations may be due to both statistical causes and genetic diversity of human and HCV populations, as well as the interaction between human immunity-related genetic systems. The existence of associations between the AB0 system and susceptibility/immunity to hepatitis C may be an additional indicator of the assessment of risk groups, which is functional for certain populations in certain sanitary and epidemiological conditions.

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Blood Groups of Recipients of COVID-19 Convalescent plasma

American Journal of Clinical Pathology ◽

10.1093/ajcp/aqab191.279 ◽

2021 ◽

Vol 156 (Supplement_1) ◽

pp. S131-S131

Author(s):

J M Petersen ◽

D Jhala

Keyword(s):

Blood Group ◽

Asian American ◽

Medical Center ◽

Blood Groups ◽

Control Population ◽

Control Group ◽

Plasma Therapy ◽

Unrelated Control ◽

Significant Difference ◽

Group B

Abstract Introduction/Objective COVID -19 Convalescent plasma therapy (CCP) is under an FDA Emergency Use Authorization to treat hospitalized patients with COVID-19. However, being ill enough to require hospitalization for COVID-19 is a negative outcome. There is also contradictory literature on whether ABO blood group is associated with worse outcomes with COVID-19 disease. Therefore, we share a regional Veterans Administration Medical Center (VAMC) experience comparing the blood groups of patients intended to receive CCP to a control group of patients positive for SARS-CoV-2. Methods/Case Report A retrospective review of all patients who had CCP ordered in the year 2020 was performed to identify the blood group of these patients, which was compared to a control population of positive patients early in the pandemic (March 17th, 2020 to May 20th, 2020). Results (if a Case Study enter NA) A total of 15 patients had CCP ordered as part of their care with an age range of 56-85 (average 69.7) years of age, entirely male composition, and a racial breakdown of 13 African Americans (86.7%), 1 Caucasian American (6.7%), and 1 Asian American (6.7%). The blood group distribution amongst these 15 patients for CCP was 1 AB+ (6.7%), 5 A+ (33.3%), 4 B+ (26.7%), and 5 O+ (33.3%). The unrelated control population consisted of 81 SARS-CoV-2 positive patients whose blood groups were distributed as 3 group AB (3.7%), 21 group A (25.9%), 15 group B (18.5%), and 42 group O (51.8%). A Chi squared test did not show a statistically significant difference between the two groups in ABO composition. Conclusion The ABO proportions of patients for whom CCP was ordered compared to the control group was not statistically significant. This provides support to the literature arguing that ABO may not be related to worse outcomes such as hospitalization or need for CCP transfusion.

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Hepatitis C infection in risk groups

Bosnian Journal of Basic Medical Sciences ◽

10.17305/bjbms.2006.3111 ◽

2006 ◽

Vol 6 (4) ◽

pp. 13-17 ◽

Cited By ~ 9

Author(s):

Sead Ahmetagić ◽

Kasim Muminhodžić ◽

Elmir Čičkušić ◽

Vildana Stojić ◽

Jasminka Petrović ◽

...

Keyword(s):

Health Care ◽

Hepatitis C ◽

Health Care Workers ◽

Drug Users ◽

Risk Groups ◽

Hcv Infection ◽

Intravenous Drug ◽

Control Group ◽

Hepatitis C Infection ◽

Care Workers

Hepatitis C infection is important global health problem with wide spectrum of health, social and economic consequences. The goal of this research was to estimate prevalence of hepatitis C virus infection in risk groups, and to determine association hepatitis C virus (HCV) infection and risk factors. Research included 4627 subjects divided in two groups. Test group included 2627 subjects divided in 4 subgroups with risk for HCV infection: those who received blood transfusion without screening on HCV (it was introduced in 1995) (700); intravenous drug users (60); patients on hemodialysis (168) and health care workers (1699). Control group included 2000 healthy volunteer blood donors. In all subjects anti-HCV antibodies were tested with third generation ELISA test. Positive serum samples were tested for presence of HCVRNA, using reaction of reverse transcription and polymerase chain reaction. In all anti-HCV positive subjects further epidemiological and clinical workup was performed. Prevalence of HCV infection in risk groups was: 4.6% in subjects who have received blood transfusions without HCV blood screening, 35% in intravenous drug users, 58.9% in patients on chronic dialysis, and 0.4% in health care workers. In control group prevalence was low (0.2%). In the group of 158 anti-HCV positive subjects, 73.4% had HCVRNA. The largest number of subjects with HCV infection was in the age group of 30-49 years (45.8%). This study showed that multiple blood transfusions before introducing the blood screening for HCV, longer duration of intravenous drug abuse, longer duration of hemodialysis treatment, larger number of accidental injuries in health care workers are independent and statistically significant risk factors for those groups examined. Results of this study confirm that general screening for HCV infection is recommended in risk groups for HCV infection in order to identify to prevent and to treat it.

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Haemorrhagic stroke in Saudi adult male population and the ABO blood group distribution: a comparative analysis

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20201433 ◽

2020 ◽

Vol 7 (4) ◽

pp. 1287

Author(s):

Mohammad P. Farshori ◽

Yasir G. Alrashdan ◽

Mohammed S. Alshammari

Keyword(s):

Blood Group ◽

Adult Male ◽

Diabetes Type 2 ◽

Fold Increase ◽

Haemorrhagic Stroke ◽

Blood Groups ◽

Control Group ◽

Stroke Patients ◽

Male Population ◽

Group B

Background: Globally stroke is leading cause of death and disability. According to WHO every year 15 million people get stroke and one third of these subjects die and about 5 million become permanently disabled. In SA smoking, diabetes, and hypertension are highly prevalent and since these factors are among ten major risk factors for stroke it puts Saudi population at higher risk of stroke. In current study we studied prevalence of hemorrhagic (HS) stroke and analyzed if there is any correlation between incidences of HS and ABO blood groups in Saudi population.Methods: Blood groups and other relevant data were collected for 2304 stroke patients registered at King Khaled hospital between 1/1/2008 to 1/6/2018. Statistical analysis was performed using Z calculator.Results: We saw 5.4-fold increase in prevalence of diabetes type 2 and 8.7 fold increase in prevalence of hypertension among HS patients as compared to control subjects. Prevalence of smoking was higher in both control and HS patients. 21.7% of stroke patients were HS patients. Distribution of A blood group was significantly higher in male HS patients. AB blood group showed statistically significant reduction in HS patients as compared to control group. Results were statistically significant at (p˂0.01). However, blood group B and O showed no significant differences between two groups.Conclusions: Results of our studies show a correlation between ABO and the incidences of hemorrhagic stroke in Saudi adult male population. Larger studies are needed to confirm these results.

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Is There a Relation between ABO Blood Groups and Clinical Outcome in Patients with Pemphigoid? A Case-Control Study

Dermatology Research and Practice ◽

10.1155/2016/3916750 ◽

2016 ◽

Vol 2016 ◽

pp. 1-5 ◽

Cited By ~ 2

Author(s):

Sedigheh Bakhtiari ◽

Parviz Toosi ◽

Somayyeh Azimi ◽

Nafiseh Esmaili ◽

Ali Montazami ◽

...

Keyword(s):

Blood Group ◽

Case Control Study ◽

Case Control ◽

Blood Groups ◽

Control Group ◽

Abo Blood Groups ◽

Chi Square ◽

Chi Square Test ◽

Group B ◽

Control Study

Background.Relationship between blood groups and dermatologic diseases remains controversial and was not yet fully elucidated nor explained clearly. The aim of this study was to examine if any relation exists between different types of pemphigoid diseases and ABO blood group.Methods.In this case-control study, 159 pemphigoid patients and 152 healthy matched-controls were evaluated. All blood group (including Rh status) data for the study was obtained from the hospital medical records. Statistical comparisons were completed with chi-square test and logistic regression.Results.Blood group “O” was found in 32.9% of patients and 38.2% of control group. Blood group “A” was found among 30.8% of patients and 34.2% of control group, while group “B” was reported in 27.4% of cases and 21.1% of controls and “AB” was identified among 8.9% of patients and 6.6% of control group. 84.9% of patients were Rh positive, while in the control group 86.2% of patients were Rh positive. No significant differences were found regarding ABO blood groups (P=0.46) or Rh (P=0.76) between pemphigoid patients and control group. Also, older females had the higher risk of developing bullous pemphigoid.Conclusion.We found no relationship between ABO blood groups and pemphigoid disease.

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Distribution of ABO and Rh blood groups in Nepalese medical students: a report

Eastern Mediterranean Health Journal ◽

10.26719/2000.6.1.156 ◽

2000 ◽

Vol 6 (1) ◽

pp. 156-158

Author(s):

T. Pramanik ◽

S. Pramanik

Keyword(s):

Medical Students ◽

Blood Group ◽

Blood Groups ◽

Blood Group A ◽

Group A ◽

Group B ◽

Group Distribution

The frequencies of ABO and rhesus blood groups vary from one population to another. We studied blood group distribution in 120 Nepalese students; 34% were blood group A, 29% group B, 4% group AB and 32.5% group O. The frequency of Rh-negative blood was 3.33% and Rh-positive 96.66%

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DISTRIBUTION OF ABO AND RH (D) BLOOD GROUPS AMONG BLOOD DONORS IN DISTRICT MARDAN, PAKISTAN

Journal of Saidu Medical College, Swat ◽

10.52206/jsmc.2013.3.2.318-322 ◽

1969 ◽

Vol 3 (2) ◽

pp. 318-322

Author(s):

MUHAMMAD KHALID ◽

NAILA ASLAM ◽

MUHAMMAD SIYAR ◽

RASHID AHMAD

Keyword(s):

Blood Group ◽

Blood Donors ◽

Local Community ◽

Healthy Adult ◽

Blood Groups ◽

Abo Blood Groups ◽

Cross Sectional ◽

Group B ◽

Abo Blood Grouping ◽

Blood Grouping

OBJECTIVE: To find out the distribution of ABO and Rh (D) blood groups among blood donors in districtMardan and to help transfusion services in the area.STUDY DESIGN: Cross sectional descriptive study.MATERIALS AND METHODS: The study was conducted in DHQ Hospital Mardan from 1st January2012 to 31st December 2012. A total of 2893 healthy adult, blood donors (both volunteer and directed) fromdistrict Mardan were included. Two ml of blood anti-coagulated with EDTA was taken and both ABO andRh (D) blood groups were determined using commercially available anti-sera of Biolaboratories. Thedistribution ofABO and Rh blood groups in the local community were then calculated.RESULTS: Among ABO blood groups “ B” (27.97%) was the most prevalent, followed by “0” (27.93%),“ A” (24.75%) and “ AB” (19.36%). Group Rh positive (94.30%) was more prevalent than Rh negative(5.70%). Similarly 0+ve (26.65%) was most frequent followed by B+ve (26.17%), A+ve (23.16%), AB+ve(18.32%), B've(1.80%),Ave(l.59%),O ve( 1.28%) and ABve( 1.04%).CONCLUSION: Blood group 'B' was most frequent among the ABO blood groups and Rh (D) positiveamong Rh blood groups while0+vewas the most frequent blood group in the study population.KEYWORDS: ABO Blood grouping, Rh (D) blood grouping, Mardan.

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Distribution Of Phenotypic And Genotypic Abo And Rhesus Blood Groups Among Bangladeshi Population

Ibrahim Medical College Journal ◽

10.3329/imcj.v5i2.10101 ◽

1970 ◽

Vol 5 (2) ◽

pp. 59-62

Author(s):

Tashmim Farhana Dipta ◽

Md Roushan Iqbal ◽

Ahmed Zahid Hossain ◽

Md Tahminur Rahman ◽

Subhagata Chowdhury

Keyword(s):

Blood Group ◽

Blood Donors ◽

Allelic Frequency ◽

Blood Groups ◽

Weinberg Equilibrium ◽

Changing Trend ◽

Hardy Weinberg Equilibrium ◽

Bangladeshi Population ◽

Group B ◽

Positive Groups

The present study is a retrospective analysis of allelic frequency of ABO and Rhesus (D) blood groups of donors attending the Deaprtment of Transfusion Medicine of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka. BIRDEM IS a 625 bed hospital, where patients and blood donors come from all parts of Bangladesh. A total of 1, 28,506 blood donors of both genders were included in the study over fourteen years from June 1995 to June 2009 for analysis. Blood group was determined by performing the both tube and slide method blood grouping method. The distribution of blood groups in our population was B>O>A>AB in Rh positive groups donors and O>B>A>AB among Rh negative donors. Blood group B was more common among the males (37.42%) while O was predominant among female donors (33.83 %). On the other hand, blood group O negative was predominant in both genders (36.88%). In this study, Hardy- Weinberg equilibrium law was used to calculate the allelic frequency for ABO/ Rh system. Homozygous allelic frequency for Rh negative population was only 0.0007. Although phenotypically B group was dominant and AB was rare in our population, but according to Hardy- Weinberg equilibrium law the estimated allelic frequency of A (0.3694) and O (0.3040) showed higher frequency than B type (0.2300) in Bangladeshi population in both homozygous and heterozygous state. So, with increasing population of Bangladesh, this changing trend in estimated blood group in ABO system may play an important role in our genetic pattern. DOI: http://dx.doi.org/10.3329/imcj.v5i2.10101 IMCJ 2011; 5(2): 59-62

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The association between blood groups and maxillofacial deformities

Indian Journal of Plastic Surgery ◽

10.1055/s-0039-1699254 ◽

2008 ◽

Vol 41 (02) ◽

pp. 138-140

Author(s):

Rasoul Gheisari ◽

Mehdi Ghoreishian ◽

Movahedian Bijan ◽

Roozbehi Amrolah

Keyword(s):

Blood Group ◽

Blood Groups ◽

Iranian Population ◽

The Other ◽

Chi Square ◽

Genetic Characteristics ◽

Blood Group A ◽

Group A ◽

Group B ◽

Group Distribution

ABSTRACT Background: Blood group is a genetic characteristic which is associated with some diseases and deformities. Multifactorial characteristics of facial development make it difficult to predict a genetic pattern in a specific maxillofacial deformity, but epidemiological evaluations can reveal relationships between such deformities and some genetic characteristics or accompanied diseases, and this will help to recognise and treat them. The aim of this study is evaluation of the relationship between blood groups and maxillofacial deformities. Materials and Methods: In this study, blood groups of 190 patients with maxillofacial deformities who had had orthognathic surgery in Alzahra hospital, Isfahan, were compared with the general Iranian population. Results: Among 190 patients, 93 cases (49%) were men and 97 cases (51%) were women. Fifteen cases (8%) were < 20 years old, 130 cases (68%) were 20-30 years old, and the others (45 cases, 24%) were > 30 years old. The blood group distribution in our samples was as follows: blood group O = 76 cases (40%), blood group A = 58 cases (30%), blood group B = 41 cases (22%), and blood group AB = 15 cases (8%). Among these patients, 31 cases (16%) had maxillary deformities and 27 cases (14%) suffered from mandibular deformities while the other 132 cases (70%) had bimaxillary problems. The Chi-square test showed statistically significant differences between the blood group distribution of the patients of this study and the normal Iranian population ( P < 0.001). Conclusion: It was shown that among different blood groups; those with blood group B have a greater likelihood of association with maxillofacial deformities. On the other hand, the probability of the association of such deformities was the least with blood group A.

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Comparison of ABO and Rh-D Blood Group Systems between the Garo Tribal People of Mymensingh and General People of Dhaka City

Journal of Enam Medical College ◽

10.3329/jemc.v1i1.11137 ◽

2012 ◽

Vol 1 (1) ◽

pp. 31-35 ◽

Cited By ~ 1

Author(s):

Rayhana Sultana ◽

Zaida Rahman ◽

Dipok Kumar Sannyal ◽

Mohammad Abdullah Al Masud ◽

Golam Morshed Molla ◽

...

Keyword(s):

Distribution Pattern ◽

Blood Group ◽

Large Scale ◽

Blood Groups ◽

Dhaka City ◽

Chi Square ◽

Tribal People ◽

Medical College ◽

Garo People ◽

Group B

Background: The distribution pattern of ABO and Rh-D blood group in our country including the tribal people is not fully established as elaborated and large scale studies have not been carried out on it. Therefore this study was designed to observe the distribution pattern of ABO and Rh-D blood groups among the Garo tribes of Mymensingh and general people of Dhaka city. Objectives: To determine and to compare the distribution pattern of ABO and Rh-D blood groups among the Garo tribal people of Mymensingh and general people of Dhaka city and to compare this distribution between this two groups. Materials and Methods: This observational study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2008 to June 2009. After proper ethical consideration total 900 Garo people of Mymensingh and 784 general people of Dhaka city were included in this study. The Garo localities and the general people of Dhaka city were selected by systematic random sampling. ABO and Rh-D blood groups were determined by the antigen antibody agglutination test of slide method. Chi square statistical analyses were done to compare the results of ABO blood group systems between the Garo people and general people of Dhaka city. Results: This study revealed that there are significant variations in the distribution of ABO and Rh-D blood groups between the Garo tribal people of Mymensingh and the general people of Dhaka city. In this study it was observed that blood group A was apparently predominant in Garo population, while blood group B was predominant in general population (p<0.001), blood group AB and O were almost similar in both groups. Rh typing of the participants reveals that majorities of both groups were Rh positive. Rh negative persons are rare in both populations, but it is extremely rare in the Garo population (0.9%). Conclusion: From the findings of the present study it can be concluded that distribution of ABO and Rh-D blood groups varies between the Garo tribal people and the general people of Dhaka city. DOI: http://dx.doi.org/10.3329/jemc.v1i1.11137J Enam Med Col 2011; 1(1): 31-35

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