scholarly journals Assessment of the haematological parameters and biochemical indices of albino rats fed with spores of Trichoderma viride

2020 ◽  
Vol 7 (17) ◽  
pp. 319-326
Author(s):  
Esther Aanuoluwa Ekundayo
Keyword(s):  
Alkaline Phosphatase ◽  
Trichoderma Viride ◽  
Alanine Transaminase ◽  
Control Group ◽  
Albino Rats ◽  
Blood Cell Count ◽  
Red Blood Cell Count ◽  
Fungal Phytopathogens ◽  
Haemoglobin Content ◽  
Biochemical Indices

The haematological as well as some enzymes biomarkers of albino rats orogastically dosed with different concentrations of Trichoderma viride as well as T. viride subjected to various treatments were evaluated. Generally, red blood cell count, haemoglobin content and packed cell volume of the control group were significantly higher than that of animals dosed with different concentrations of T. viride. The same trend was observed when T. viride was amended with 1% lactose, sodium nitrate and sodium chloride. There were no significant differences in the alanine aspartate, alkaline phosphatase and alanine transaminase values of animals dosed with lower concentrations of T. viride. This study suggests that lower concentration of T. viride could be used in controlling fungal phytopathogens.

scholarly journals The effect of obesity and Insulin Resistance on Liver Enzymes in Type2 Diabetes Mellitus

2015 ◽  
Vol 12 (3) ◽  
pp. 536-545
Author(s):  
Baghdad Science Journal
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Alkaline Phosphatase ◽  
Negative Correlation ◽  
Liver Enzymes ◽  
Alanine Transaminase ◽  
Obese Group ◽  
Control Group ◽  
Diabetic Patients ◽  
And Control

Diabetes mellitus (DM) has been defined as a clinical syndrome that is characterized by abnormal carbohydrate metabolism. The chronic hyperglycemia of diabetes is associated with long term damage, dysfunction, and failure of different organs, especially the liver .This study was conducted to assess the effect obesity and insulin resistance on liver enzymes in diabetic Iraqi patients.A comparative study of (90) Iraqi adults divided to three subgroup(30) obese ,(30) nonobese diabetic patients and(30)person had used as control. The analysis included Liver enzyme ALP,ALT,AST,GGT ,Fasting Plasma Glucose (FBG) , Lipid Profile , Hemoglobin A1C , insulin and homeostasis model assessment of insulin resistance (HOMA IR) were measured. Subjects were excluded from this study if they had liver disease, alcohol intake, medications for lowering lipid, insulin treatment, pregnant women and women taking contraceptive pills . The study shows significantly higher of liver enzymes level ( gamma glutamyl transpeptidase (GGT), alkaline phosphatase, Aspartate Amino Transferase , Alanine Transaminase) in obese diabetic patients compared with non-obese diabetic patients and control subject and HOMA IR showed significantly higher in obese diabetic patients compared with non-obese with diabetic patients and control (P < 0.05). The lipids level showed significantly higher in obese diabetic patients compared with non-obese diabetic patients and control.The HbA1c level showed higher significantly in obese diabetic patients compared with control and ther is a posative correlation between insulin and HOMA IR , ALP in obeses diabetic patients while there was negative correlation between ALT and cholesterol in obese group and with HbA1c in control group. The liver enzymes level of(alkaline phosphatase, alanine transaminase, aspartate transaminase gama glutaminase transferase ) is significantly higher in obese diabetic patients than non –obese diabetic patients and control group , also There was posative correlation between ALP and HOMA IR while there was negative correlation between ALT and cholesterol in obese group and with HbA1c in control group .

scholarly journals Antihyperglycemic and Antihyperlipidemic of Karala (Momordica charantia) Fruits in Streptozotocin Induced Diabetic Rats

2012 ◽  
Vol 5 (1) ◽  
pp. 29-37 ◽  
Author(s):  
MA Hossain ◽  
M Mostofa ◽  
D Debnath ◽  
AKMR Alam ◽  
Z Yasmin ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Body Weight ◽  
Total Cholesterol ◽  
Aqueous Extract ◽  
Diabetic Rats ◽  
Momordica Charantia ◽  
The Body ◽  
Control Group ◽  
Albino Rats ◽  
Higher Doses

To investigate the antihyperglycemic and antihyperlipidemic effect of Momordica charantia (Karala), the aqueous extract of the Karala fruit was tested on streptozotocin (STZ)-induced diabetic rats. Thirty six albino rats were used in the experiment, 30 diabetic and the remaining six as negative control (T1). Diabetes was induced by administering (injecting) STZ at dose of 55mg/kg body weight. Thirty diabetic animals were randomly divided into five groups such as diabetic control group (T2) without any application of treatment, and groups T3,T4,T5 and T6 were treated with aqueous extract of Karala fruits daily at the doses of 250,    500 and 750mg/kg and glibenclamide (at a dose of 5mg/kg body weight) respectively. The body weight was taken and blood samples were collected from individual animal to determine glucose levels at 15 day interval up to 90 days. In addition, Asparate  Transaminenase(AST), Alanine Transaminenase(ALT), Alkaline Phosphatase(ALP), Total cholesterol (TCh) and Triglyceride (TGA) were determined at day 15 and at the end of the experiment. All three doses of Karala extracts reduced diabetic induced blood sugar and the reduction is comparable with standard glibenclamide (GLM) dose particularly with higher doses Karala extracts (500 and 750mg). Karala also prevented body weight loss due to induced diabetes as did by GLM treatment.. The treatment also resulted in a significant reduction of Asparate Transaminenase(AST), Alanine Transaminenase(ALT), Alkaline Phosphatase(ALP), Total cholesterol (TCh) and Triglyceride (TGA) activities of treated rats when compared to the STZ induced  diabetic rats. Higher doses of Karala (500 and 750mg/kg) are as effective as standard GLM dose on measured variables. This study demonstrated that Karala has hyperglycemia and antihyperlipidemic effect against STZ induced diabetic rats. These findings open the possibility of using Karala extract to treat diabetic animal and human patients although further research is warranted. DOI: http://dx.doi.org/10.3329/jesnr.v5i1.11550 J. Environ. Sci. & Natural Resources, 5(1): 29 - 37, 2012  

scholarly journals The Reasearch on the Anti-Fatigue Effect of Whey Protein Powder in Basketball Training

2015 ◽  
Vol 9 (1) ◽  
pp. 330-334 ◽  
Author(s):  
Sun Ronghui
Keyword(s):  
Whey Protein ◽  
Cycle Ergometer ◽  
Control Group ◽  
Blood Cell Count ◽  
Hematological Indices ◽  
Fatigue Effect ◽  
High Intensity Training ◽  
Red Blood Cell Count ◽  
Improve Exercise Capacity ◽  
Intensity Training

In order to observe the effects of whey protein powder on hematological indexes of players majoring in physical education in the basketball training, the authors divided the players randomly into a control group and a nutrition group. Athletes complete the 30 minutes quantitative exercise using cycle ergometer respectively before the trial and after one month trial. Then we exsanguinated immediately after exercise, extracted heparin and measured hemoglobin, red blood cell count, hematocrit and mean corpuscular volume and other hematological indices. The results showed that after taking whey protein powder, the HB, RBC, HCT of nutrition group was significantly higher that the control group. This suggests that in high-intensity training, taking whey protein powder can cause changes of HB, RBC and HCT in human body, meanwhile MCV essentially the same. So whey protein powder can improve exercise capacity, and has anti-fatigue effect.

scholarly journals The Influence of High Iodine Intake on Chosen Blood Parameters of Sheep

2014 ◽  
Vol 62 (1) ◽  
pp. 71-79
Author(s):  
Hana Dušová ◽  
Jan Trávníček ◽  
Zdeněk Peksa ◽  
Kristýna Šimák-Líbalová ◽  
Anna Šimková ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Blood Cell ◽  
Alkaline Phosphatase Activity ◽  
Iodine Intake ◽  
Blood Cell Count ◽  
Total Proteins ◽  
High Iodine ◽  
Group A ◽  
Red Blood Cell Count ◽  
Group B

The objective of the study was to evaluate the influence of high iodine intake in ewes on haematological and biochemical parameters of the blood of ewes and their lambs. Twelve pregnant ewes of the Sumava sheep breed and their newborn lambs were included in the experiment. Control group (A) consisted of 6 ewes with 7 lambs and experimental group (B) comprised 6 ewes with 6 lambs. The feed ration was enriched with calcium iodate by addition of 3 and 5 mg/kg in group A and group B, respectively. The studied parameters in ewes and lambs were haematocrit value, red blood cell count and haemoglobin concentration in blood, concentration of urea and total proteins, and alkaline phosphatase activity in blood plasma. No differences were found out in haematocrit value, red blood cell count, concentration of haemoglobin and total proteins between groups of ewes A and B with their lambs. Urea concentration and alkaline phosphatase activity were higher in ewes of group B and their lambs during the entire experimental period. An increase in the values of urea and alkaline phosphatase in the group of ewes and lambs with higher iodine intake indicates a potential risk of high iodine intake associated with changes in the thyroid activity in ewes and their lambs.

scholarly journals Haematological and serum biochemical indices of broiler chickens fed graded levels of inorganic and chelated trace minerals

2020 ◽  
Vol 47 (2) ◽  
pp. 46-50
Author(s):  
A. A. Ayoola ◽  
A. O Fafiolu ◽  
O. O Oluwatosin ◽  
O. A Osinowo ◽  
O. W. Ariyo
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
Broiler Chickens ◽  
Environmental Concern ◽  
Basal Diet ◽  
Serum Biochemistry ◽  
Trace Minerals ◽  
Blood Cell Count ◽  
Red Blood Cell Count ◽  
Biochemical Indices

Poor bioavailability of inorganic trace elements used in broiler nutrition and their subsequent release into the environment via poultry excereta is major cause of biological and environmental concern. Hence, the need to explore the use of Chelated trace minerals in broiler diets. This study was carried out to evaluate the effect of supplemental inorganic and chelated Cu, Zn and Mn on haematology and serum biochemistry of broiler chickens. A 42-day feeding trial was conducted using a total of 300 Arbor acre broiler chickens. The birds were allocated to five dietary groups. Each group had six replicates containing 10 birds. The treatments were control (basal diet), 100% inorganic trace minerals (ITMs) supplemental level (15, 100, 100 mg/kg for Cu, Zn, Mn respectively), 50% ITMs supplemental level (7.5, 50, 50 mg/kg of Cu, Zn, Mn), 50% Chelated trace minerals (CTMs) supplemental level (7.5,50, 50 mg/kg of Cu, Zn, Mn) and 25% CTM supplemental level (3.75, 25, 25 mg/kg of Cu, Zn, Mn, in that order). A lower (p<0.05) white blood cell count (11.07x106/mm3) and an improved (p<0.05) red blood cell count (13x106/mm3) was observed for the group fed 50% CTM supplemental level. The group fed 50% supplemental level of CTM had the highest (p<0.05) total protein (73.2 g/L), albumin (41.20 g/L) and globulin (32 g/L) in serum as compared tothe other groups. The serum Cu, Zn and Mn were significantly higher (p<0.05) for the grou fed 25% supplemental diet of CTM. It can be concluded that trace minerals supplementation increased serum trace minerals of broiler chicken.

EFFECTS OF EARLY FEEDING OF STRAINED MEAT TO PREMATURELY BORN INFANTS

PEDIATRICS ◽  
1952 ◽  
Vol 9 (4) ◽  
pp. 485-491
Author(s):  
M. B. ANDELMAN ◽  
P. S. GERALD ◽  
A. C. RAMBAR ◽  
B. M. KAGAN
Keyword(s):  
Serum Protein ◽  
Red Blood Cell ◽  
Protein Concentration ◽  
Control Group ◽  
Blood Cell Count ◽  
Control Groups ◽  
Red Blood Cell Count ◽  
Experimental Group ◽  
Breast Fed ◽  
Prematurely Born Infants

This study was undertaken to determine the effect on prematurely born infants of the feeding of strained meat. One group of infants received a standard formula; another an identical formula to which strained meat was added, and a third group was breast fed. Meat added to the diet of prematurely born infants weighing between 2000 and 6750 gm. was well accepted. There was no significant difference in the symptoms or signs of illness among the infants of either of the three groups. It was found that a plot of the body weight of such infants against age generally gives a smooth sigmoid curve. The central portion of the "S" forms a remarkably straight line. The linear portion of the curve is located in the interval between 2500 and 4500 gm. body weight. The location is relatively unaffected by either age or birth weight. The slope of this linear portion was taken as the measure of the weight gain. A similar relationship was found for the crown-heel length. These findings are not only of academic interest but are also of practical importance since they provide an unusually good tool for further nutritional and other studies. Growth as measured by rate of change of weight and length did not differ significantly between the experimental group and the control group. The breast-fed group exceeded the experimental and control groups in both weight and length gain. The greater weight gain in the breast-fed group as compared to the experimental group was statistically significant. Minimum values for red blood cell count and hemoglobin were observed at 12 weeks of age. These values rose steadily until about 20 weeks of age, at which time they became relatively stable. There was no significant difference in the hemoglobin concentration or red blood cell count between the three groups at 12 weeks of age. At 20 weeks, however, the meat-fed or experimental group exceeded the control by a significant amount. The mean difference in hemoglobin concentration of the experimental group and that of the control group was 1.0 gm./100 cc. This finding is of interest especially since the experimental and control groups both received more than adequate amounts of iron added to the diet. A gradual rise in serum protein concentration was noted with increasing age. At 12 weeks of age, the serum protein concentration for the breast-fed group was significantly lower than that for the experimental group, the average difference being 0.40 gm./100 cc. The average difference between these two groups at 20 weeks was 0.35 gm./100 cc. but there were too few in the breast-fed group at this time to give the difference statistical significance. The serum protein concentrations in the experimental and the control groups did not differ significantly at either 12 or 20 weeks of age. Analysis of the total volume intake of the formulae showed that intake of the experimental group was reduced in proportion to the greater caloric content of the meat-containing formula. The result was that the daily intake of calories was the same in both the experimental group and the control group. This remarkable reduction in volume of intake by premature infants in the weight groups concerned and the strikingly uniform caloric intake are of interest particularly in view of current thoughts on self selection of diet. No differences were noted in the weight or length gain, hemoglobin, red blood cell count, or serum protein concentration between the experimental group and the control group when the infants reached one year of age.

scholarly journals Digestive Fermentation, Antioxidant Status, and Haemato-Biochemical Indices of Growing Rabbits Fed on Diets Supplemented with Ziziphus spina-christi Leaf

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Suha Hashim Abduljawad
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
Antioxidant Status ◽  
Control Diet ◽  
Organic Matter Content ◽  
Control Group ◽  
Chemical Compositions ◽  
Blood Cell Count ◽  
High Level ◽  
Biochemical Indices

The objective of the study was to assess the effect of diets supplemented with Ziziphus spina-christi leaf on digestive fermentation, antioxidant status, and haemato-biochemical indices of growing rabbits. Ziziphus leaves (ZLs) of Ziziphus spina-christi were collected from Sidr trees scattered throughout the city of Medina, Saudi Arabia. Three formulated diets containing 0, 10, and 20 g Ziziphus spina-christi/Kg diet as supplementation were offered ad libitum. The organic matter content of ZL was higher. Chemical compositions were comparable in all of the contents of the tested diet. Quantities of gas released from the control diet were higher, and then the gases released decreased significantly (P<0.05) with the addition of ZL. The values of NH3-N were taken as the same trend. The addition of a high level of ZL to rabbit diets led to a decrease (P<0.05) in the total count of bacteria as well as the number of E. coli and Clostridium spp. However, the number of Enterococcus bacteria was not affected by supplementation. Haemoglobin parameters of the control group and groups 2 and 3 were compared: white blood cell count and red blood cell count. These observations of total protein and albumin within the range of reference values were reported in healthy rabbits, while glucose significantly decreased with the addition of ZL and AST in the blood increased significantly. The values of TP, albumin, and ALT measurements showed no significant differences among groups fed on test diets. Significant differnces in serum immunoglobulins were observed between the groups, while the high levels of ZL supplement led to a significant (P<0.05) increase in the serum IgA, IgG, and IgM levels. Antioxidants expressed as T-AOC, GSH-Px, T-SOD, and CAT in the blood of animals fed on diets containing high levels of ZL were significantly higher. Higher serum T-AOC, T-SOD, and CAT activities were observed in rabbits supplemented with a high level of ZL compared with the control group (P<0.05). The supplementation of ZL tended to increase serum GSH-Px activity. The addition of ZL to rabbit diets led to an increase in dry matter intake. On the other hand, there was no significant change in the apparent digestion coefficient of DM, OM, CP, and fat. Conclusion. Dried ZL supplementation up to 20 g/Kg diet might improve the bacterial community, antioxidants, biochemical parameters and blood constituents of rabbits, and digestibility.

scholarly journals Effect of different proportions of popped amaranth grain (Amaranthus cruentus) as an iron supplement in piglet diets on selected blood indicators

2015 ◽  
Vol 84 (3) ◽  
pp. 277-287
Author(s):  
Miroslav I. Urosevic ◽  
Isabel Hennig-Pauka ◽  
Alexander Tichy ◽  
Nenad Stojanac ◽  
Radomir Ratajac
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
Red Blood Cell ◽  
Haemoglobin Concentration ◽  
Daily Weight Gain ◽  
Control Group ◽  
Blood Cell Count ◽  
Amaranthus Cruentus ◽  
Amaranth Grain ◽  
Red Blood Cell Count

The aim of our study was to compare the effect of various proportions of popped amaranth grain (Amaranthus cruentus) in piglet diets on selected blood indicators, such as red blood cell count (RBC), haematocrit (HCT), haemoglobin concentration (HB) and mean corpuscular haemoglobin concentration (MCHC), but also growth efficiency (daily weight gain) and tissue morphology of the gastrointestinal tract. Altogether, 122 piglets (12 litters) were divided randomly into four groups (4 × 3 litters). Diet of the piglets in the control group was without popped amaranth grain. Starting from day 5 until day 90 of life, each of the three experimental groups was offered one of the feed mixtures containing different amounts of heat-treated popped amaranth grain: 20% (group A20), 40% (group A40), and 79% (group A79). When comparing the three experimental groups with the control group, in relation to the mean haemoglobin concentration and red blood cell count, higher values were measured in almost all periods of the piglets’ life, except for five-day-old piglets in the experimental groups. Only in 90-day-old piglets, group A79 tended to have a higher body weight compared to the control piglets. In summary, differences in haematologic indices which occurred between groups were inconsistent and of minor practical impact. With regard to the costs of the Amaranthus diet, beneficial effects were not obvious.

scholarly journals Hyperglycaemic Environment: Contribution to the Anaemia Associated with Diabetes Mellitus in Rats Experimentally Induced with Alloxan

Anemia ◽  
2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Oseni Bashiru Shola ◽  
Fakoya Olatunde Olugbenga
Keyword(s):  
Diabetes Mellitus ◽  
Reticulocyte Count ◽  
Test Group ◽  
Diabetic Rats ◽  
Control Group ◽  
Albino Rats ◽  
Plasma Haemoglobin ◽  
Sterile Normal Saline ◽  
Red Blood Cell Count ◽  
Glucose Plasma

Background. Diabetes mellitus characterized by hyperglycaemia presents with various complications amongst which anaemia is common particularly in those with overt nephropathy or renal impairment. The present study has examined the contribution of the hyperglycaemic environment in diabetic rats to the anaemia associated with diabetes mellitus. Method. Sixty male albino rats weighing 175–250 g were selected for this study and divided equally into control and test groups. Hyperglycaemia was induced with 170 kgbwt−1alloxan intraperitoneally in the test group while control group received sterile normal saline. Blood samples obtained from the control and test rats were assayed for packed cell volume (PCV), haemoglobin (Hb), red blood cell count (RBC), reticulocyte count, glucose, plasma haemoglobin, potassium, and bilirubin.Result. Significant reduction (P<0.01) in PCV (24.40±3.87versus40.45±3.93) and haemoglobin (7.81±1.45versus13.39±0.40) with significant increase (P<0.01) in reticulocyte count (12.4±1.87versus3.69±0.47), plasma haemoglobin (67.50±10.85versus34.20±3.83), and potassium (7.04±0.75versus4.52±0.63) was obtained in the test while plasma bilirubin showed nonsignificant increase (0.41±0.04versus0.24±0.06).Conclusion. The increased plasma haemoglobin and potassium levels indicate an intravascular haemolytic event while the nonsignificant increased bilirubin showed extravascular haemolysis. These play contributory roles in the anaemia associated with diabetes mellitus.

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