scholarly journals Evaluation of the influence of individualized protective ventilation on the lung mechanical properties

2021 ◽  
Vol 17 (6) ◽  
pp. 58-63
Author(s):  
T.S. Kuzmenko ◽  
S.I. Vorotyntsev

The work is devoted to the study of the influence of individualized protective ventilation support on pulmonary mecha-nics. The study included 47 patients who underwent open abdominal surgery under general anesthesia. All patients had a moderate to high risk of developing postoperative pulmonary complications by the ARISCAT scale. Intraoperatively, the impact of individualized protective ventilation on respiratory mechanics, namely Ppeak, Pplat, Pdrive, dynamic pulmonary compliance was assessed. Individualized protective respiratory support was ventilation with a tidal volume of 7 ml/kg of ideal body weight, with the selection of the optimal level of positive pressure at the end of exhalation (PEEP), focusing on dynamic pulmonary compliance and performing recruiting maneuver, and then in the case of a decrease in dynamic pulmonary compliance by more than 20 %, followed by re-selection of PEEP. The studied parameters were recorded before and after the recruiting maneuver, as well as on the 30th, 60th, 90th, 120th, 150th, 180th minutes after the recruiting maneuver, depending on the duration of the operation. The use of alveolar straightening techniques led to an improvement in pulmonary mechanics, namely, an increase in dynamic pulmonary compliance by 16 % and a decrease in Pdrive by 17 %. The intraoperative level of PEEP averaged 4 [4; 5] cm of water. No cases of hypoxemia or recurrence of recruiting maneuver were reported. The obtained results indicate that chosen technique of recruiting maneuver is effective and safe, and its use allows reducing the negative impact of mechanical ventilation. The study did not find a statistically significant correlation between the level of PEEP and the value of dynamic pulmonary compliance. Such data prove the need for individual selection of ventilation parameters according to the characteristics of the mechanical properties of each patient.

2021 ◽  
Vol 13 (10) ◽  
pp. 5494
Author(s):  
Lucie Kucíková ◽  
Michal Šejnoha ◽  
Tomáš Janda ◽  
Jan Sýkora ◽  
Pavel Padevět ◽  
...  

Heating wood to high temperature changes either temporarily or permanently its physical properties. This issue is addressed in the present contribution by examining the effect of high temperature on residual mechanical properties of spruce wood, grounding on the results of full-scale fire tests performed on GLT beams. Given these tests, a computational model was developed to provide through-thickness temperature profiles allowing for the estimation of a charring depth on the one hand and on the other hand assigning a particular temperature to each specimen used subsequently in small-scale tensile tests. The measured Young’s moduli and tensile strengths were accompanied by the results from three-point bending test carried out on two groups of beams exposed to fire of a variable duration and differing in the width of the cross-section, b=100 mm (Group 1) and b=160 mm (Group 2). As expected, increasing the fire duration and reducing the initial beam cross-section reduces the residual bending strength. A negative impact of high temperature on residual strength has also been observed from simple tensile tests, although limited to a very narrow layer adjacent to the charring front not even exceeding a typically adopted value of the zero-strength layer d0=7 mm. On the contrary, the impact on stiffness is relatively mild supporting the thermal recovery property of wood.


2015 ◽  
Vol 57 (4) ◽  
pp. 224-232
Author(s):  
Jarosław Siwiński ◽  
Katarzyna Kubiak ◽  
Miłosz Tkaczyk ◽  
Anna Mazur ◽  
Ryszard Rekucki

Abstract The study was conducted to perform a comparative analysis of the mechanical properties of wood samples derived from oaks in the Krotoszyn Plateau, which depend on the health state of the trees. Strength parameters of oak wood were calculated for selected diseased and healthy trees (according to the Roloff classification). The study was conducted by a modified method described in the standard Polish Norm PN EN 408+ A1: 2012. For testing, prior selection of wood samples showed that more wood samples of diseased trees compared with those of healthy oaks did not fulfil the Polish standard requirements. According to the method used, the average results of strength tests of timber structures from healthy oaks exhibited higher strength parameters than those of the diseased trees.


Nafta-Gaz ◽  
2021 ◽  
Vol 77 (3) ◽  
pp. 208-214
Author(s):  
Michał Pajda ◽  
◽  
Wojciech Mazela ◽  

The aim of the work was to present the issue of eco-efficiency, based on the PN-EN ISO 14045:2012 standard in relation to the production of fatty acid methyl esters (FAME). The ecoefficiency analysis takes into account economic and environmental aspects in the improvement of products and processes / technologies. Eco-efficiency considers the product and technology throughout the life cycle, from the construction phase, through use to decommissioning. The impact on the natural environment is assessed on the basis of: consumption of energy, materials, dust and gas emissions, waste and sewage. Total costs include: production costs, raw material costs, costs during the use phase including maintenance, repair and operating costs, product disposal or recycling. The eco-efficiency analysis is helpful in making decisions regarding the selection of a new product or designing a new technology, and enables the selection of the variant that is the most economical and has the least possible impact on the natural environment. These issues are particularly important in the case of biofuels. The rapid growth of their production and the European Union’s policy, which aims to increase the share of energy from renewable sources, cause concerns of many experts regarding the threats related to the production of biofuels, both for the environment and food security. In particular, efforts are made to minimize the amount of waste and residues by implementing the idea of a circular economy. This approach promotes the development of new technologies that are more environmentally friendly. Due to the regulations set out in the RED and RED II Directives, there is a chance that the biofuels will have a less negative impact on the environment. This results from the obligation to certify compliance with the sustainability criteria, which is carried out by voluntary systems recognized by the European Commission, such as the KZR INiG System.


Author(s):  
Faiz Fakhri Isjwara

The principle of the organization of prisons (Lembaga Pemasyarakatan/ LAPAS) must prioritize a humane approach so that prisoners and prisoners receive their rights. If the implementation is good, the objective of LAPAS is to carry out social reintegration, namely the restoration of the unity of life, life and livelihood of prisoners and correctional students both prisoners as individuals, social beings and God's creatures with society can be achieved. However, this organization faces obstacles, namely the problem of overcapacity. This can have implications for suboptimal and can even lead to failure to function as a correctional institution. The problem of over capacity will also have an impact on the health conditions of prisoners. Sleep conditions, eating patterns, health services that are less than the maximum due to over capacity will certainly have a negative impact on the nutritional status of prisoners. This study aims to determine the impact of Overcapacity Impacts on the Nutritional Status Level of Prisoners in Class II A Penitentiary, Sidoarjo. This type of research is a quantitative correlational analytic survey with a cross-sectional design. The number of samples was 91 inmates. The sampling technique is by random sampling. Data is collected by weighing body weight and height and comparing with ideal body weight. The results showed that the more overcapacity, the nutritional status of prisoners decreased. Room conditions can affect the provision of an unbalanced diet. Thus, that this causes the prisoners to experience malnutrition.


2019 ◽  
Vol 20 ◽  
pp. 187-195 ◽  
Author(s):  
Rita Remeikienė ◽  
Ligita Gasparėnienė

Our article concentrates to the main aim – to assess the impact of emigration on an origin economy. This topic was chosen because the theoretical research has disclosed that the positive impact of emigration usually manifests through monetary transfers to a native country while the negative impact mainly emerges as a reduction in the labour force, which, in its turn, causes deterioration of a country’s demographic and economic situation. It has been found that the growing flows of emigration significantly reduce Lithuanian population and cause “brain drain”. High emigration rates also have a negative impact on Lithuanian national economy, in particular, its unemployment rate (the opposite effect). To reduce the rates of emigration from the country, Lithuania must develop and improve such ALPM’s elements as combination of work and dual vocational training, targeted selection of the industries for arrangement of an apprenticeship, manual training, dual vocational training and workplace training, segmentation of the unemployed by the indications of employment impediment, individual work with the unemployed to restore their basic skills (motivation, practice, health improvement), vocational guidance of young people (students) and early involvement of students into the labour market by combining studies and work.


Paradigm ◽  
2017 ◽  
Vol 21 (1) ◽  
pp. 75-90
Author(s):  
Shivendra Singh ◽  
Atul Dhyani

Family is one entity that has complex variables underplaying the consumption decisions, and marketers must understand how couples behave in concert to resolve conflict across major decisions. In this study, the family aspects are investigated to shed more light on spouse attitude towards family decision-making for selection of car and school/college for their ward and assess the impact of attitudinal factor on decision satisfaction. The drop-off/pick-up method was used to collect the data from Northern India. The result reveals that spousal attitude is formed by marital power, assertiveness, subtle manipulation, love, bargaining and being submissive. Results of multiple regression analysis show that subtle manipulation is most and marital power has a negative impact on spouses’ decision satisfaction. Thus, when targeting a family for a significant trades assay, the salesperson should focus on both husband and wife and stimulate a conversation between them to appeal to their conjoint kinship.


Author(s):  
Katrina Knight ◽  
Pamela Moalli ◽  
Stacy Palcsey ◽  
William Barone ◽  
Steven D. Abramowitch

Pelvic organ prolapse (POP) is a common disorder with a profoundly negative impact on the physical and psychological health of women worldwide; however, the exact etiology is currently unknown. Parity, defined as the number of births, is commonly identified as one of the leading risk factors for the development of POP. The objective of this study was to examine the impact of parity on the uniaxial mechanical properties of the sheep vagina along the longitudinal direction. The findings of this study revealed that parity negatively impacts the tangent modulus (54% decrease), tensile strength (54% decrease), and strain-energy density (47% decrease) of the vagina in the ewe (female sheep). Based on similar findings in primate, these data suggest that the ewe may serve as a cheaper alternative for studying the pathogenesis of POP moving forward.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Jitendra Yadav ◽  
Madhvendra Misra ◽  
Nripendra P. Rana ◽  
Kuldeep Singh

PurposeThe paper aims to explore the influence of cybersecurity on the semantic orientation of the sports consumers. Focusing on both sport and esports, this study finds the social media factors contributing in the sentiment formation and commenting behavior on Twitter and proposes a scheme for attitude modulation through identification of highly engaged nano-influencers.Design/methodology/approachExperimental design was used as the research methodology. Data mining from Twitter using RStudio software was conducted using the keyword “cybersecurity” during the time of pandemic. Final corpus of 31,891 tweets were considered for the study. Initial sentiment analysis has been conducted to explore the consumer's emotional inclination towards cybersecurity. Further through generalized equation modeling the impact of social media attributes over the consumer's posting behavior has been analyzed.FindingsThe research findings reveal that users are inherently positive towards cybersecurity adoption in sports and the factors such as number of tweets, number of positive words contained in these tweets and the authenticity of the information source boost the pre-established tweeting behavior. However, the influx of information from non-organizational sources such as trending topics and discussions have negative impact over the users.Originality/valueThis study is first to explore the role of nano-influencers as communication moderators over digital social platforms. This study offers a new understanding of key contributing attributes of sentiments formation over social media and offers a scheme of selection of nano-influencers to modulate the pre-established sentiments of the users. Finally, the current study offers valuable insights into social media engagements and selection of nano-influencers for practicing marketing managers.


ESMO Open ◽  
2020 ◽  
Vol 4 (Suppl 2) ◽  
pp. e000765 ◽  
Author(s):  
Giuseppe Banna ◽  
Alessandra Curioni-Fontecedro ◽  
Alex Friedlaender ◽  
Alfredo Addeo

New cases of the novel coronavirus, also known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continue to rise worldwide. A few reports have showed that mortality due to SARS-CoV-2 is higher in elderly patients and other active comorbidities including cancer. To date, no effective treatment has been identified and management for critically ill patients relies on management in intensive care units. Patients with lung cancer are at risk of pulmonary complications from COVID-19. Furthermore, the use of chemotherapy might have a negative impact in patient’s outcome. Therefore, the risk/benefit ratio of systemic anticancer treatment (SACT) has to be considered. For each patient, several factors including age and comorbidities, as well as the number of hospital visits for treatment, can influence this risk. Each hospital around the world has issued some internal policy guidelines for oncologists, aiming to limit risks during this difficult time. We hereby propose a tool to support oncologists and physicians in treatment decision for patients with lung cancer. There are several variables to consider, including the extent of the epidemic, the local healthcare structure capacity, the risk of infection to the individual, the status of cancer, patients’ comorbidities, age and details of the treatment. Given this heterogeneity, we have based our suggestions bearing in mind some general factors There is not easy, universal solution to oncological care during this crisis and, to complicate matters, the duration of this pandemic is hard to predict. It is important to weigh the impact of each of our decisions in these trying times rather than rely on routine automatisms.


2020 ◽  
Vol 5 (1) ◽  
pp. 22-30
Author(s):  
Charles A. Oyelami ◽  
Tesleem O. Kolawole ◽  
Gabriel S. Ojo

Cemeteries have been identified as a possible source of groundwater and environmental pollution. This may be due to wrong siting of cemeteries, poor soil selection and very thin vadose zone. Over the years, most communities around Osun State experience a number of communicable diseases like dysentery, diarrhea and typhoid, especially after episodes of flash floods. Therefore, this study was carried out to audit the impact of burial practices on the immediate environment viz-a-viz their interaction with both surface and groundwater which forms the main source of potable water for the communities. Method of approach include; assessing possible water contamination, studying the vadose hydrological characteristics as well as studying the geotechnical properties of soils within the vadose zone. Water samples from the vicinity of both cemeteries shows probable contamination with an average pH of 6.19 for Ede and 6.57 for Iragbiji, EC with an average 480μS for Ede and 1210μS for Iragbiji. Biological constituents found within the area include; enterobacteriaceae (salmonella spp., serratia spp., proteus spp., shigella spp.), suggesting likely contamination of both surface and groundwater around the vicinity of the cemeteries. Most cations and anions analysed for (Mg2+, NO3-, SO42-, and PO43-) comply with the WHO standards based on their maximum permissible limits (MPL). Geotechnical investigations revealed that soils within the study areas are largely unsuitable for a standard cemetery due to their high moisture content, poor grading characteristics, low compaction value, poor hydraulic characteristics and shallow water level. The study concluded that cemeteries from both towns have a negative impact on their immediate environment due to poor selection of soil materials (porous and permeable sandy soil) as reflected in the quality of surface and groundwater.


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