scholarly journals IN VIVO STUDY OF PHENOLIC COMPOUNDS ROLE ON ANTIHYPERCHOLESTEROL ACTIVITY OF VIRGIN COCONUT OIL

2010 ◽  
Vol 8 (1) ◽  
pp. 119-123
Author(s):  
Tri Joko Raharjo ◽  
Ariyani Setyo Widhiyati ◽  
Endah Mulya Asih ◽  
Sumiaty Sumiaty ◽  
Raden Tambunan ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Blood Serum ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Serum Cholesterol Level ◽  
Coconut Oil ◽  
Serum Total Cholesterol ◽  
Virgin Coconut Oil

The role of phenolic compounds on antihypercholeserol activity of Virgin Coconut Oil (VCO) has been investigated. The in vivo studies ware carried out by treatment of two groups of Wistar white mouse (Ratus norvegicus) using high phenolic VCO and low phenolic VCO respectively, followed by analysis of lipid profile in blood and liver serum of the mouse. In addition a group of hypercholesterol mouse was treated with low phenolic VCO and the blood serum lipid profile was compared with untreated hypercholesterol mouse. The results show that phenolic compound play an important role on antihypercholesterol of VCO. Group of mouse treated with high phenolic VCO have better lipid profile (blood serum: total cholesterol: 70 mg/dL, triglyceride: 76 mg/dL, HDL: 20 mg/dL, LDL: 35 mg/dL; liver serum: total cholesterol:7 mg/dL, triglyceride: 19 mg/dL) compared with the group treated with low phenolic VCO (blood serum: total cholesterol: 82 mg/dL, triglyceride: 100 mg/dL, HDL: 21 mg/dL, LDL: 41 mg/dL; liver serum: total cholesterol: 9 mg/dL, triglyceride: 34 mg/dL). Hypercholesterol mouse tests shown that low phenolic VCO treatment result in decreasing of blood serum cholesterol level by 52.10% which was not significantly different compared to untreated mouses (decreasing of blood serum cholesterol level by 48.61%).   Keywords: antihypercholesterol, phenolic compound, VCO, in vivo

scholarly journals LIPID PROFILE IN COPD PATIENTS

2021 ◽  
Vol 5 (11) ◽  
Author(s):  
Ramavatar Bairwa ◽  
Pratibha Pareek
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Serum Cholesterol Level ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Serum Concentrations ◽  
Sectional Study ◽  
Cross Sectional ◽  
Copd Patients

Background: The COPD patients are expected to have a deranged lipid profile for various reasons like smoking, aging, and using such drugs as steroids. Aims of study to estimate the lipid profile level in COPD patients. Methods: This cross-sectional study was conducted on 50 COPD patients and including 50 control were enrolled in the study. Results: The lipid profile in COPD patients, unpaired t test was performed and it was observed that COPD patients showed significantly higher serum levels of TC, TG, LDL and serum concentrations of HDL were also decreased significantly compared to controls. Conclusion: COPD patients showed significantly higher serum cholesterol level in COPD patients as compared to controls. Keywords: Total cholesterol, TG, COPD.

scholarly journals PENGARUH DIET EMULSI VIRGIN COCONUT OIL (VCO) TERHADAP PROFIL LIPID TIKUS PUTIH (Rattus norvegicus)

2020 ◽  
Vol 17 (1) ◽  
pp. 18
Author(s):  
FETI FATIMAH ◽  
BARLINA RINDENGAN
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Rattus Norvegicus ◽  
Ldl Cholesterol ◽  
Coconut Oil ◽  
Hdl Cholesterol ◽  
Virgin Coconut Oil ◽  
Group I ◽  
Study Results ◽  
Pap Method

<p>ABSTRAK</p><p>Virgin Coconut Oil (VCO) merupakan salah satu produk panganfungsional yang populer di masyarakat. Cita rasa VCO dapat diperkayadalam bentuk emulsi mengandung sari buah nenas. Penelitian inidilakukan untuk mengetahui pengaruh diet emulsi VCO terhadap profillipid tikus (Rattus norvegicus) yang sebelumnya diinduksi hiperlipidemiadengan lemak babi 180g/100g ransum dan kuning telur bebek dengandosis 4 ml/hari. Penelitian dilakukan bulan Januari sampai Desember 2009di Laboratorium Balai Penelitian Tanaman Kelapa dan Palma Lain(BALITKA), Laboratorium FMIPA Universitas Sam Ratulangi Manado,Laboratorium UPHP (Unit Penelitian Hewan Percobaan) UniversitasGadjah Mada Yogyakarta serta Laboratorium PAU IPB Bogor. Delapanbelas tikus dibagi secara acak ke dalam 3 kelompok (6 tikus perkelompok). Kelompok I adalah kelompok kontrol yang diberi akuades,kelompok II diberi diet emulsi VCO, dan kelompok III diberi diet VCOmurni. Kandungan kolesterol total, HDL, LDL, dan triasilgliserol diukursetelah akhir perlakuan dengan metode enzimatik. Kadar kolesterol totaldiukur menggunakan metode CHOD-PAP, kadar kolesterol LDLmenggunakan metode PVS, kadar kolesterol HDL menggunakan metodeCHOD-PAP dan kadar triasil gliserol menggunakan metode GPO-PAP.Hasil penelitian menunjukkan bahwa konsumsi 0,945ml/hari VCO dan3,78ml/hari emulsi VCO selama 7 hari dapat menurunkan kadar kolesteroltotal, kadar kolesterol LDL, serta meningkatkan kadar kolesterol HDLdarah tikus Wistar secara signifikan (=0,05), sedangkan penurunan kadartriasilgliserol hanya ditunjukkan oleh konsumsi emulsi VCO (=0,05).Dengan demikian, emulsi VCO yang diperkaya dengan sari buah nenasberperan lebih baik dari VCO murni dalam menurunkan kolesterol padahewan uji tikus.</p><p>Kata kunci: Virgin coconut oil (VCO), emulsi VCO, profil lemak</p><p>ABSTRACT</p><p>Effect of Virgin Coconut Oil (VCO) Emulsion Diet onLipid Profile of White Rats (Rattus norvegicus)</p><p>Virgin Coconut Oil (VCO) is a functional food product that ispopular in the society. VCO-emulsion is a VCO emulsified with pineapplejuice. This study was conducted to find out the effect of VCO-emulsiondiet on lipid profile of mouse (Rattus norvegicus) strain wistar which wasalready treated by inducting hyperlipidemia using lard (180g/100g) andyolk (4ml/days). This research was conducted from January to December2009 at the Laboratory of Coconut and Other Palm Trees ResearchInstitute (BALITKA), the Laboratory of FMIPA Sam Ratulangi UniversityManado, the Laboratory of Experiment Animal Research Unit GadjahMada University Yogyakarta, and the Laboratory of PAU IPB Bogor.Eighteen mice were randomly divided into 3 groups. Group I was thecontrol group treated with aquadest only, group II was treated with VCO-emulsion diet, and group III was treated with pure VCO diet. The contentof total cholesterol, HDL, LDL, and triacylglicerol were measured at theend of the treatment using enzymatic method. In this study, there weresome methods used for measurements: CHOD-PAP method for level oftotal cholesterol, PVS method for level of LDL cholesterol, CHOD-PAPmethod for level of HDL cholesterol, and GPO-PAP method for measuringlevel of triacylglicerol. The study results showed that diet of 0.945ml/daysof VCO and 3.78ml/days of VCO emulsion for 7 days significantlydecreased the level of total cholesterol and the level of LDL cholesterol,and increased the level of HDL cholesterol in the blood of Wistar mouse(α=0.05). Whereas it was shown that only by diet of VCO emulsion(α=0.05) decreased the level of triacylglicerol. Thus, VCO emulsionsignificantly lowered cholesterol in the experimental mouse better thanpure VCO diet only.</p><p>Key words : Virgin coconut oil(VCO) , VCO emulsion, lipid profile</p>

scholarly journals Clinical Investigations of the Effect of Citrus unshiu Peel Pellet on Obesity and Lipid Profile

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Seongil Kang ◽  
Sangyeol Song ◽  
Joosang Lee ◽  
Hyekyung Chang ◽  
Sanghun Lee
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Weight Control ◽  
Large Scale ◽  
Total Cholesterol Level ◽  
Experimental Studies ◽  
Density Lipoprotein ◽  
Citrus Unshiu ◽  
The Impact

Objectives. Several experimental studies have reported antiobesity and lipid-improving effects of Citrus unshiu. However, clinical studies on its effects are lacking. This study was designed to evaluate the impact of Citrus unshiu peel pellet (CUPP) on obesity and lipid profile. Methods. For 118 patients with body mass index (BMI) > 23 who took Citrus unshiu peel pellet (CUPP) for 4 weeks in a Public Health Center, laboratory and biometric readings before and after CUPP administration were analyzed. Results. Mean age of these subjects was 53.8±10.6 years (range: 18-75 years). There were 88 (74.6%) females in the study sample (n = 118). A significant (p < 0.01) decrease in BMI from 27.47±2.24 to 27.27±2.22 was observed in all subjects after CUPP treatment and 65.3% (N = 77) of them lost 1.03±0.83 kg of weight after 4 weeks of treatment. Total cholesterol level was significantly (p < 0.01) decreased from 204.0±37.4 mg/dL to 193.5±36.5 mg/dL. Significant (p < 0.05) decreases in levels of low-density lipoprotein, cholesterol, and triglyceride were also observed. Conclusions. These results suggest that CUPP in practice could help weight control and improve total cholesterol level. Findings of this study provide clinical foundation for future large-scale trials to establish clinical benefits of CUPP.

scholarly journals BODY SCRUB VIRGIN COCONUT OIL, COFFEE GROUNDS AND CARBON ACTIVE COCONUT SHELL AS A MOISTURIZER AND SKIN BRIGHTENING

2021 ◽  
Vol 17 (1) ◽  
pp. 62-67
Author(s):  
Putri Desi Eka ◽  
Djamil Ratna ◽  
Faizatun Faizatun
Keyword(s):  
Fatty Acids ◽  
Activated Carbon ◽  
Coffea Arabica ◽  
Coconut Oil ◽  
Virgin Coconut Oil ◽  
Medium Chain ◽  
Medium Chain Fatty Acids ◽  
Coffee Grounds ◽  
Black Color

Relevance. Virgin Coconut Oil (VCO) contains a lot of medium chain fatty acids, combined with coffee grounds (Coffea Arabica Linn.) and activated carbon (Activated carbon coconut Nucifera L) into a preparation that can moisturize and brighten the skin. Objective. The purpose of this study was to make cosmetic cleansing preparations containing three natural ingredients. Methods. This study evaluates the organoleptic body scrub preparations, homogeneity, dispensability, and pH. The ingredients were tested using in-vivo and clinical irritation along with the effectiveness of the preparation (moisture and brightness). Results. Organoleptic testing and homogeneity were confirmed to have dark black color, the distinctive smell of coffee, homogeneity, spreadability in the range of 4 cm, and the pH was at a safe pH for the skin so that irritation results also did not show edema and erythema both in-vivo divided into 3 groups (n = 3) and clinically (n = 30). In addition, this body scrub provides moisture and brightness to the skin for 2 months of use, p <0.05. Conclusions. VCO body scrub preparations, coffee grounds, and activated carbon are preparations that have the potential to be cosmetic cleansers.

Relationship between serum total cholesterol level and nutritional status in Japanese young female

1999 ◽  
Vol 19 (8) ◽  
pp. 1145-1152 ◽  
Author(s):  
Kazue Itoh ◽  
Katsumi Imai ◽  
Takashi Masuda ◽  
Shimako Abe ◽  
Hitomi Nakao ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
Young Female ◽  
Serum Total Cholesterol ◽  
Serum Total Cholesterol Level

Virgin coconut oil complements with its polyphenol components mitigate sodium fluoride toxicity in vitro and in vivo

2021 ◽  
pp. 1-7
Author(s):  
Soorya Parathodi Illam ◽  
Sruthi Panniyan Kandiyil ◽  
Arunaksharan Narayanankutty ◽  
Soumya Valappan Veetil ◽  
Thekkekara Devassy Babu ◽  
...  
Keyword(s):  
Sodium Fluoride ◽  
Coconut Oil ◽  
Fluoride Toxicity ◽  
Virgin Coconut Oil ◽  
Toxicity In Vitro

THE EFFECT OF DIETARY OILS AND FATTY ACIDS ON CHOLESTEROL METABOLISM IN THE RAT

1958 ◽  
Vol 36 (1) ◽  
pp. 433-438 ◽  
Author(s):  
J. D. Wood ◽  
B. B. Migicovsky
Keyword(s):  
Fatty Acids ◽  
Total Cholesterol ◽  
Lauric Acid ◽  
Opposite Effect ◽  
Cholesterol Metabolism ◽  
Coconut Oil ◽  
Liver Cholesterol ◽  
Dietary Oils ◽  
Liver Homogenates

Rats were fed diets containing 20% oils and 9% fatty acids and the effect of these compounds on cholesterol metabolism was studied. Unsaturated oils and fatty acids increased total cholesterol in the liver and stimulated the incorporation of C14-acetate into cholesterol both in vivo and in liver homogenates. Saturated material such as coconut oil and lauric acid had the opposite effect with respect to amount of liver cholesterol and to in vivo incorporation. The saturated material had no significant effect on synthesis in homogenates. The effect of oils in the diet was rapid, the stimulating effect of rapeseed oils being observed after the rats had been placed on the diet for as short a period as 3 days.

scholarly journals Efek ekstrak daun sirsak (Annona muricata Linn) terhadap profil lipid tikus putih jantan (Rattus Norvegicus)

2014 ◽  
Vol 3 (1) ◽  
pp. 7-12 ◽  
Author(s):  
Indrawati Wurdianing ◽  
SA Nugraheni ◽  
Zen Rahfiludin
Keyword(s):  
Treatment Group ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Ldl Cholesterol ◽  
Total Cholesterol Level ◽  
Wilcoxon Test ◽  
Control Group ◽  
Annona Muricata ◽  
The Mean

Background: Lipid profile effects is a risk factor for Coronary Heart Disease. Soursop leaves (Annona muricata L) isa traditional medicine plant containing metabolic compounds that contribute to the improvement of the lipid profile.Objective: To determine the effects of soursop leaves extract on lipid profile (total cholesterol, LDL cholesterol, HDLcholesterol and triglyceride).Methods: An experimental study using randomized pre-posttest with control group design. Sample consisted of 28 maleWistar rats, were divided into four groups. The control group (K) was only given High Fat High Cholesterol (HFHC)diet and treatment groups (P1, P2, P3) were given a HFHC diet plus Annona muricata L extract with doses of 100, 200and 300 mg/kgBB per day for 28 days respectively. Data were analyzed by Wilcoxon test, Kruskal-Wallis and MannWhitney.Results: The mean total cholesterol level significantly decreased in the treatment group P1 (p = 0.028) from 60.7 mg/dl(47.6-75.3) to 45.5 mg/dl (38.4-62.4). Mean HDL cholesterol level significantly increased in the treatment group P2(p=0.043) from 26.0 mg/dl (19.7-35.3) to 27.9 mg/dl (18.8-38.0). The mean levels of LDL cholesterol and triglyceridedecreased but not significantly.Conclusion: The administration of Annona muricata L extract can decrease total cholesterol and increase HDLcholesterol significantly.

Sign in / Sign up

Export Citation Format

Share Document