scholarly journals THE ANALYSIS OF a-CRYSTALLINE PROTEIN IN WHITE AND BRUNESCENT CATARACT

Author(s):  
MUHAMMAD HIDAYAT ◽  
ELLYZA NASRUL ◽  
TJAHJONO GONDHOWIHARJO ◽  
ANDANI EKA PUTRA

Objectives: The objectives of the study were to determine the difference of concentration and expression of α-crystalline protein in white and brunescent cataract lenses. Methods: The design of this study is cross-sectional comparative. The subject was cataract patients who underwent cataract surgery in Puskesmas Pariaman, West Sumatra, Indonesia. Lens examination was carried out at the Microbiology Laboratory of FK Unand from July 2019 to February 2020. The samples consisted of 36 subjects who met the inclusion criteria. ELISA examination was used to determine the concentration of α-crystalline protein and Western Blot examination was performed to see the expression of the α-crystalline protein in all subjects. Results: The difference in the concentration of α-crystalline protein in white cataract and brunescent cataract was not statistically significant, with p=0.129 (p>0.05). The result of Western blot examination was normal expression of α-crystalline protein in white cataract and under expression of α-crystalline protein in brunescent cataracts. Conclusion: The expression of α-crystalline protein appeared to be different between white and brunescent cataract lenses. In brunescent cataract, under expression of α-crystalline proteins was related to the decrease of chaperone activity. This change occurred allegedly because of photochemical reaction that happened inside the lens.

2017 ◽  
Vol 13 (2) ◽  
pp. 125
Author(s):  
Firdinia Gafuri Dohamid ◽  
M. Darwin Prenggono ◽  
Dona Marisa

Abstract: Breast cancer is the most common malignancies among woman in Indonesian. One of breast cancer treatment is chemotherapy which resist cancer’s cells to grow. But chemotherapy also cause DNA damage that interfere lymphocyte proliferation. Depletion on lymphocyte counts will increased patient’s susceptibility to opportunistic infection. The aim of this research was to knowing the difference of lymphocyte counts because of chemotherapy on breast cancer patients in general hospital Ulin Banjarmasin. This research was an observational analytic with cross sectional approach. The sampling technique was non-probability sampling followed by consecutive sampling. Total samples were 61 patients that match with inclusion criteria. Paired T-test was used to analyze the hypothesis with the result of pvalue=0.000 (ρ<0.05), that means there’s a significant decrease in the number of lymphocyte counts after receiving chemotherapy in general hospital Ulin Banjarmasin, January 2014 to December 2015 period. Keywords: chemotherapy, lymphocyte, breast cancer


2020 ◽  
Vol 8 (2) ◽  
pp. 36-41
Author(s):  
Fachreza Aryo Damara

Background: Health prevention and promotion are both important in making better public health. In order to actualize both aspects, Posyandu cadre play major role. Cadre have bigger chance and impact to educate the people who are living around them. However, doing a direct education has become more difficult since physical contacts were minimalized during this COVID-19 outbreak. Therefore, an effective tele-education is needed as an effort to prevent COVID-19 transmission. The study aims to evaluate the effect of tele-education through Youtube and Whatsapp to enhance people's understanding on COVID-19 transmission prevention Method: The study was a cross-sectional study with observational descriptive-analytical methods and quantitatively approach. Subject of the study was Posyandu cadre in Burangrang Village, Lengkong District, Bandung with the subject total was 19. Results: After given a tele-education, there was an increase in total score means between pretest and posttest with p=0.000 (p<0.001). Moreover, there were increases in both social media’s impression and engagement on educational video which was uploaded on Youtube. Discussion: In doing tele education to Posyandu cadre, video as a media to deliver the content was more preferred. Sharing the knowledge through video along with evaluating participants' understanding of the given topics could enhance cadre knowledge about handwashing as a prevention in the middle of COVID-19 outbreak. Conclusion: Tele education using video could enhance cadre’s understanding about handwashing. The media that has been used was able to deliver the content based on impression and engagement evaluations.


2016 ◽  
Vol 13 (1) ◽  
pp. 27
Author(s):  
Rachmawati Widyaningrum ◽  
Detty Siti Nurdiati ◽  
Indria Laksmi Gamayanti

Background: Preparing quality human resource for the future, children are being the most attention of the growth and development optimally. Critical aged of them is 0-2 years old. Pregnancy and giving birth on adolescence are still being the factors. Knowledge and feeding practice are also factors being the basic need for children development optimally.Objective: To know the difference between knowledge, feeding practice, and children development aged 6-24 months on adolescent and adult mother in Kasihan Primary Health Care, Bantul district, Yogyakarta.Method: This research was observational with a cross-sectional design. It held on July -September 2015 in work area of Kasihan subdistrict, Bantul district, Yogyakarta. Population defined as mother aged 15-40 years that lives in Kasihan subdistrict. The sample was taken using nonprobability consecutive technique sampling. It was got 66 children aged 6-24 months old with no having congenital defects, no following special development stimulation program,  and being able and want to follow this research as inclusion criteria. In this research, a mother was measured of knowledge level and feeding practice to her child, even though the child was measured off his/her development using BSID III. Data were analyzed using Chi-Square.Results: Adolescent mothers had a significantly larger proportion of children experiencing developmental disorders and feeding practices are less good compared with adult mothers.Conclusion: Adult mother has better knowledge and feeding practice than adolescent mothers. Adult mother also has a child with better developmental status than adolescent mothers.


Jurnal Medali ◽  
2021 ◽  
Vol 3 (1) ◽  
pp. 20
Author(s):  
Adam Reza Pahlevi ◽  
Erdianto Setya Wardhana ◽  
Erna Dwi Agustin

Background: An electronic medical record is a medical system that can be used to store information about the track of a patient`s health. The completeness format of Electronic Medical Record used the format of Electronic Medical Record Guidance from Health Ministry Year 2015. The safety of electronic medical records has 6 aspects as follows privacy, integrity, authenticity, availability, access, control, non-rapadiatum.Method: This research aimed to know the description of the completeness format and the safety of The Electronic Medical Record at RSIGM Sultan Agung Semarang. This research used descriptive observational using a cross-sectional method. The subject of this study was Electronic Medical Records in March 2020. The samples were selected according to the inclusion criteria obtained from RSIGM Sultan Agung SemarangResult: The result of this research was used to know the description of the completeness of Electronic Medical Record Format and the safety of Electronic Medical Record at RSIGM Sultan Agung Semarang.Conclusion: The conclusion of this research showed Electronic Medical Record had been applied at RSIGM Sultan Agung Semarang but there are still lack in the informed consent form and the informed refusal, the safety of the electronic medical record was still lack in the electronic signature format.


2021 ◽  
Vol 6 (2) ◽  
pp. 128
Author(s):  
Fillah Fithra Dieny ◽  
Firdananda Fikri Jauharany ◽  
A. Fahmy Arif Tsani ◽  
Choirun Nissa

The COVID-19 pandemic impacts lifestyle changes, one of which is the eating behavior of people. The research aims to examine changes in eating behavior before and during the COVID-19 pandemic among adolescents and adult groups in Indonesia. A cross-sectional study on 563 subjects, with the subject's inclusion criteria, namely living in Indonesia, aged 12-55 years, willing to participate in the research by filling in informed consent and filling out a questionnaire via an online google form. The data obtained were grouped based on variables before and after the pandemic, then tested the normality of the data. Bivariate analysis used the Wilcoxon text because the data were not normally distributed. As a result, there was an increase in the subject's breakfast habits and frequency of eating. Subjects experienced changes in eating habits, namely an increase in the frequency, variety, and portion of consumption of animal protein, vegetable protein, vegetables, and fruit between before and during the COVID-19 pandemic (p <0,001). In addition, the habit of consuming fluids, supplements, and spices also experienced a significant increase, while the pattern of snacking decreased between before and during the pandemic (p <0,001). In conclusion, there were differences in eating behavior: breakfast habits, dietary variations, consumption of animal and vegetable protein, vegetables, fruits, fluids, supplements, spices, and snacking patterns outside the home between before and during the pandemic in the subject


e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Mutiara Aprilia Senolinggi ◽  
Maya Mewengkang ◽  
John Wantania

Abstract: This stuady aimed to investigate the relationship between age of menarche to menopause in women of District Kakas of North Sulawesi in year 2014. This was a cross sectional analytic approach. Samples were taken by using purposive sampling method, in which only the samples that met the inclusion criteria that can be the subject of this study. The results showed that the value of Sig. is 0043 with a value of α = 0.05 so it could be concluded that the Sig. <0.05, then Ho is rejected and Ha accepted. It is claimed that there is a relationship between age of menarche to menopause. Correlation value (R) is 0.274 can be interpreted that the relationship between age of menarche to menopause age in the weak category because the value of the correlation <0.5. Regression models obtained Y = 58.364 to 0.879 x (y = age of menopause, x = age of menarche). Conclusion: There was a relationship between the ages of menarche to the age of menopause in women. The earlier menarche occurs, the slower the menopause arises. Conversely, the slower the menarche occurs sooner menopause arises.Keywords: age, menarche, menopauseAbstrak: Penelitian ini bertujuan untuk mengetahui hubungan antara usia menarche dengan usia menopause pada wanita di Kecamatan Kakas Sulawesi Utara tahun 2014. Penelitian ini bersifat analitik dengan pendekatan cross sectional. Sampel diambil menggunakan metode purposive sampling, dimana hanya sampel yang memenuhi kriteria inklusi yang dapat menjadi subyek penelitian ini. Hasil penelitian menunjukkan bahwa nilai Sig. adalah 0.043 dengan nilai α = 0,05 sehingga dapat disimpulkan bahwa Sig. < 0,05 maka Ho ditolak dan Ha diterima. Hal ini menyatakan bahwa ada hubungan antara usia menarche dengan usia menopause. Nilai korelasi (R) adalah 0,274 dapat diinterpretasikan bahwa hubungan antara usia menarche dengan usia menopause ada di kategori lemah karena nilai korelasi < 0,5. Model regresi yang diperoleh Y = 58,364 – 0,879 X (y = usia menopause, x = usia menarche)Simpulan: Terdapat hubungan antara usia menarche dengan usia menopause pada wanita. Makin dini menarche terjadi, makin lambat menopause timbul dan sebaliknya.Kata kunci : usia, menarche, menopause


2019 ◽  
Vol 2 (1) ◽  
pp. 10-15
Author(s):  
Dyhan Purna Setia ◽  
Ferdinal Ferry ◽  
Dovy Djanas

Objective : To find the difference in mean hemostatic factors in severe preeclampsia and eclampsia.Method : The study was analytic descriptive using a cross sectional study design by looking at the subject's Medical Record according to the time and place of research. The sample is the entire medical record of pregnant women who suffer from preeclampsia and eclampsia in the obstetric and gynecology departments of Dr. M. Djamil Padang Hospital in the period 15 January 2016 to 31 December 2017. The assessment was in the form of assessed platelet levels, PT, APTT and D-Dimer. Samples were taken from populations that met the inclusion criteria and did not have exclusion criteria. Sampling using consecutive sampling techniques taken from the Medical Record Dr. M.Djamil Padang. Statistical analysis to assess significance using the T-Test.Result : The severity the condition of pregnancy the lower the platelet mean and PT. Significant differences were obtained between platelets in PEB and eclampsia (p> 0.05). The mean PT, APTT and D-Dimer showed no significant differences in pregnancy conditions. Statistical test with T-Test did not show significant differences in mean PT, APTT, and D-dimer between eclampsia and PEB (p> 0.05).Conclusion : There were significant differences in mean in platelets, whereas in PT, APTT, and D-dimers in PEB and eclampsia there were no significant differences.Keywords: Pregnancy, severe preeclampsia, eclampsia, platelets, PT, APTT, D-Dimer.


2021 ◽  
Vol 53 (3) ◽  
pp. 138-142
Author(s):  
Hadi Susiarno ◽  
Ryandra Prakasa ◽  
Budi Handono

Urinary incontinence (UI) is a commonly overlooked problem in women, particularly women of post-menopausal age. Despite the medical, social, and hygiene burdens conferred by UI to its sufferers, past studies have shown that only a few among women afflicted with UI sought treatment. This may be due to various reasons: lack of knowledge and awareness of UI or a wrong belief of UI as a natural part of aging. This study aimed to investigate the association between knowledge and severity of UI and reasons for not seeking treatment among post-menopausal women in Bandung, Indonesia. This was an analytic cross-sectional study conducted at the Geriatric and Gynecology Clinic, Dr. Hasan Sadikin General Hospital, in September 2013. Ninety-one women who met the inclusion criteria were interviewed to assess their knowledge of UI. The severity of UI was assessed using Urinary Distress Inventory 6 (UDI-6). Data were analyzed using the chi-square test. Sixty-five respondents (70.7%) had poor knowledge of UI. Knowledge of UI was not associated with awareness of UI as a medical condition (p=0.633). The difference in UI severity was associated with the perception of UI as a normal part of aging (p=0.008). Post-menopausal women are poorly informed regarding urinary incontinence. However, knowledge alone might not be adequate to encourage women to seek treatment. Further studies are needed to investigate women’s reasons for not seeking treatment for UI.


2017 ◽  
Vol 6 (2) ◽  
Author(s):  
Sri Surini Pudjiastuti ◽  
Agus Setyo Nugroho ◽  
Luluk Fuadah

Abstract : AMPnoPRO, AMPPRO, Transfemoral Prosthesis, Mobility Level. Transfemoral amputation is the amputation of the limbs that is performed between the hips and knees This amputation is a state that affects the patient's unthinking life. The loss of the limb causes disruption of lower limb function, thus indirectly disturbing its mobility. The purpose of this study was to determine the effect of Prosthesis on the level of mobility ability of transfemoral amputation patient. The Amputee Mobility Predictor (AMP) study on improving mobility of transfemoral prosthesis users using one-pretest and post-test group design studies, one group pretest-postes design including preexperiments. This study used a cross-sectional approach. In this design is done pretes to know the condition of the beginning of the subject before being treated so that researchers can know the condition of the subject studied before or after being treated which results can be compared or seen changes. Nine Subjects aged between 17-27 years, Using unilateral transfemoral prosthesis, muscle strength stump≥4, Normal joint motion scope. From wilcoxon statistic test obtained t = -2.687 with p = 0.007, because p <0,05, it can be concluded "there is influence of transfemoral prosthesis to the level of mobility ability in transfemoral amputation patient". The prosthesis has a higher level of mobility than the mobility level with other tools. The difference in functional level of other mobility aids (ABM) is level k-2 whereas the level of prosthesis is k-3 level.


2017 ◽  
Vol 4 (1) ◽  
pp. 44
Author(s):  
Nashriatul Mawaddah ◽  
Kusuma Arbianti ◽  
Niluh Ringga W

Background: Normal children had sensing capabilities to do oral health assessments. The inability to hear that was suffered by the deaf children caused obstacles to do oral health assessments. The dental and periodontal conditions were important for healthy life in general. The objective of this research was to know the difference Community Index Periodontal Treatment Needs (CPITN) between normal children in SD N 1 Tegaldowo Sragen with deaf children in SLB-B YPSLB Gemolong. Method: This research used observational method with Cross Sectional strategy. The subject of this research consist of 31 deaf children dan 83 normal children. Periodontal conditions from the two groups were measured by WHO probe. After the measurement, the CPITN index would be determined by looking at the highest score. The research was analyzed by using statistic non-parametric test from Mann-Whitney. Results: The result was 0.0003 (p<0.05), revealing there was a significant difference of CPITN index from normal children and deaf children. Conclusion: In conclusion, the highest periodontal status from normal children was gingival bleeding that meant they need to be given a conseling and demonstation about oral helath. The highest score from deaf children revealed the presence of subgingival and supragingival calculus that meant they needed to be given a counseling and demonstration including scaling treatment.


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