scholarly journals Current regulations for Herbal Medicines in India

2021 ◽  
Vol 9 (2) ◽  
pp. 30-34
Author(s):  
Saloni Singh ◽  
Vikesh Kumar Shukla
Keyword(s):  
Side Effects ◽  
Herbal Medicines ◽  
Herbal Products ◽  
Herbal Plants

India is a major source of herbal plants and medicines. There are substantial numbers of plants and herbs which are used as medicines and people prefer them due to fewer side effects. In India, herbal medicines are regulated by AYUSH, CDSCO (Central Drugs Standard Control Organization), AND D&C Act 1940 & 1945(amendment). About 8000 herbal medicines have been organized in AYUSH systems in INDIA. This article is about how herbal products are regulated in India.

Medicinal Plants and Natural Products, More Effective and Safer Pharmacological Treatment for the Management of Obesity

2021 ◽  
Vol 22 ◽  
Author(s):  
Harsha Negi ◽  
Meenakshi Gupta ◽  
Ramanpreet Walia ◽  
Moayad Khataibeh ◽  
Maryam Sarwat
Keyword(s):  
Natural Products ◽  
Weight Gain ◽  
Side Effects ◽  
Medicinal Plants ◽  
Mechanism Of Action ◽  
Pancreatic Lipase ◽  
Herbal Products ◽  
Prevalence Of Obesity ◽  
Herbal Plants ◽  
New Compounds

: Obesity is a major lifestyle disorder and it is correlated with several ailments. The prevalence of obesity has elevated over the years and it has become a global health problem. The drugs presently used for managing obesity have several side-effects associated with them such as diarrhoea, leakage of oily stools, etc. On the contrary, herbal plants and natural products are considered safe for use because they have lesser side effects. New compounds isolated from medicinal plants are screened and identified to determine their effectiveness and potential in preventing abnormal weight gain. In this review, the medicinal plants and natural materials were surveyed across the literature to cover those that have potential for managing and controlling weight gain, and their mechanism of action, active component, and experimental methodologies are also included. These herbal products can be developed as formulations for therapeutic use in obesity. The herbal plants mentioned in the review are classified based on their mechanism of action: inhibition of pancreatic lipase and appetite suppression activities. The ability to inhibit pancreatic lipase enzyme has been used to determine the effectiveness of herbal products for the prevention of abnormal weight gain because of its action on dietary fat and suppression of appetite. This review is an attempt to summarize the herbal plants and natural products that can be used to develop formulations effective in controlling weight gain and obesity.

scholarly journals Some Thoughts on the Safety Issues Relating to Chinese Herbal Products

2005 ◽  
Vol 1 (2) ◽  
pp. 462-469
Author(s):  
Dan Bensky ◽  
Erich Stöger
Keyword(s):  
Health Care ◽  
Side Effects ◽  
Herbal Medicines ◽  
Developed Countries ◽  
Patient Encounter ◽  
Herbal Products ◽  
Safety And Efficacy ◽  
Medical Practitioners ◽  
Safety Issues ◽  
Chinese Herbal

As Chinese medicine becomes more and more integrated into the fabric of health care in economically developed countries, it runs into a variety of problems. These relate to education, licensing, and communications. In this article, we would like to focus on one important aspect—what does it mean to prescribe Chinese herbal medicines (CHM) responsibly at the present time? This issue confronts all Chinese herbalists (CH) in almost every patient encounter, and involves two major points that medical practitioners of all persuasions have to be cognizant of and which could be approached in a number of ways: safety and efficacy. How do we prescribe in a way that promotes the health of the patient without doing harm? We need to remember that all medicines, herbal or otherwise, have potential side effects and risks to patients, and that we need to take appropriate measures.

The Mechanistic Approach to Tackle Obesity Using Traditional Herbal Plants

2021 ◽  
pp. 104-123
Author(s):  
Saniyah Saleem Khan
Keyword(s):  
Side Effects ◽  
Herbal Medicines ◽  
World Health ◽  
Mechanistic Approach ◽  
Life Threatening ◽  
Herbal Plants ◽  
Treatment Of Obesity ◽  
Health Organization ◽  
Surgical Treatments ◽  
Global Health Problem

Obesity is a medical metabolic condition where a person accumulates excess body fat that might affect their health. Obesity is a prevalent global health problem linked with other life-threatening chronic diseases like cardiovascular, certain types of cancer, diabetes, renal, cerebrovascular, bone, and muscle-related diseases. According to the World Health Organization (WHO), obesity is the fifth foremost cause of global deaths. Many allopathic drugs and surgical treatments for managing obesity are available in the market. However, these conventional methods have adverse side effects and chances of recurrence. For more than 2,000 years, herbal medicines have been used for the treatment of many diseases efficiently. This chapter addresses the current progress in the effectiveness of several herbal medications used for the treatment of obesity without causing side effects. The possible effects and mechanisms of using these herbaceous plants in the treatment of obese and overweight humans and animals are covered extensively.

scholarly journals Herbal pharmacovigilance in Nepal: challenges and recommendations

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 111 ◽  
Author(s):  
Sunil Shrestha ◽  
Krisha Danekhu ◽  
Binaya Sapkota ◽  
Nisha Jha ◽  
Bhuvan KC
Keyword(s):  
Side Effects ◽  
Adverse Effects ◽  
Focal Point ◽  
Herbal Medicines ◽  
World Health ◽  
Self Medication ◽  
Herbal Products ◽  
Health Authorities ◽  
Pharmacovigilance Center ◽  
Health Organization

Traditional herbal medicine is widely used globally. Despite its extensive use, there are no proper regulations on standardization and use of herbal medicinal products. Nepal has a rich biodiversity and demography comprising of different socio-ethnic groups. Herbal medicines are utilized prominently in Nepalese communities. These herbal products may cause side effects and adverse effects, such as nephrotoxicity, neurotoxicity with the heavy metal toxicity associated with their powdered dosage forms. The side effects of using herbal products have been documented, such as bleeding with use of Ginkgo biloba and increase in blood pressure with use of Ephedra. Regulation of herbal products is essential to promote their optimal and rational use. Standard tools are available for assessing adverse effects of herbal products from health authorities, like the World Health Organization. In Nepal, self-medication practice using traditional herbal medicines is common and includes the concomitant use of allopathic. There is no focal point to address the regulatory issues on herbal products currently in Nepal. The Department of Drug Administration in Nepal is nominated as a national pharmacovigilance center and there are no reports on adverse events from the use of herbal medicines so far. However, not having any reports does not ensure the absolute safety and effectiveness of herbal products, so vigilance is warranted. Herbal pharmacovigilance is needed for Nepal to ensure safe and effective use of herbal medicines as the current pharmacovigilance ecosystem does not capture those cases. In the Nepalese context, the absence of reporting mechanisms may have underreported adverse cases of herbal products. The present opinion article aims to discuss the use of herbal products in Nepal, the challenges associated with the adverse reaction due to herbal medicines, and recommendations to overcome these challenges

Herbal Drugs as Immune Booster against Viral Infections

2021 ◽  
Vol 17 ◽  
Author(s):  
Gyanendra Mohapatra ◽  
Biswa Mohan Sahoo ◽  
Bimalendu Chowdhury ◽  
J. Sruti ◽  
Rabi Narayan Rana ◽  
...  
Keyword(s):  
Immune System ◽  
Side Effects ◽  
Viral Infections ◽  
Curcuma Longa ◽  
Herbal Medicines ◽  
Passive Immunization ◽  
Ocimum Sanctum ◽  
Herbal Drugs ◽  
Herbal Plants ◽  
Immune Booster

: The immune system involves both active and passive immunization. The antibodies are devloped against the antigens during active immunization and are permanently stored. But, in case of passive immunization, the antibodies are exposed to the same antigens in every person who are already infected. In order to enhance the immune systems i.e. innate and adaptive immune responses, herbal plants are used as immune booster. Some of the herbal plants have been proved clinically to enhance the immunity that include Morniga oleifera (Drumstick), Azadirachta indica (Neem), Ocimum sanctum (Tulsi), Withania somnifera (Aswagandha), Zingiber officinale (Ginger), Allium sativum (Garlic), Curcuma longa (Turmeric), Emblica officinalis (Amla) etc. Compared to synthetic drugs, the herbal drugs have fewer or less side effects and stimulate the immune system to defend against various foreign pathogens. Even though, herbal medicines are usually considered as safe and effective therapy, but it is clinically proved that if a drug is effective, it would have some side effects. But, sometimes the antioxidant property of herbal medicines is helpful to reduce the toxicities produced by any toxic substances or any drugs. This review aims to encourage the study of various herbal constituents and their role in the treatment of different types of viral infections.

scholarly journals A Review on unexplored Plants for Recurrent Aphthous Stomatitis

2020 ◽  
Vol 13 (3) ◽  
pp. 253-260
Author(s):  
K. Anand Babu ◽  
R. Ram Narayanan
Keyword(s):  
Clinical Trials ◽  
Gastric Ulcer ◽  
Side Effects ◽  
Animal Models ◽  
Herbal Medicines ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Pathological Conditions ◽  
Mouth Ulcer ◽  
Herbal Plants

Recurrent Aphthous Stomatitis (RAS) is one of the most common pathological conditions with ulcers in the oral mucosa. Various conventional medicines are available in the market for RAS but due to a range of factors people are getting affected by RAS gradually. More over conventional medicines are all having the side effects so the alternative system for the treatment of RAS came in to the market. Although herbal medicines are widely used in India and other countries and multiple studies are conducted in this regard, but still many of the herbal plants are not utilized though they are having traditional claim. Aim of this is review is suggesting the herbal plants which are claimed for the treatment of mouth ulcer but scientifically validated for gastric ulcer by using animal models should also be validated for mouth ulcer by clinical trials and also which are used traditionally but not yet concentrated can be evaluated and used for the treatment of RAS.

Herba Reudeuep With Modification of Heating In Virgin Cocanut Oil

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Wahyuzan Wahyuzan ◽  
Lukmanul Hakim ◽  
Rahmat Afrizal ◽  
Asmeri Lamona ◽  
Khairuni Khairuni ◽  
...  
Keyword(s):  
Modern Medicine ◽  
Heating Time ◽  
Agricultural Product ◽  
Average Yield ◽  
Herbal Products ◽  
The Public ◽  
Randomized Design ◽  
Herbal Plants ◽  
Medicinal Properties ◽  
Completely Randomized Design

Traditional medicine in Indonesia has been known by the public before formal health services using modern medicine. Indonesia has many type of herbal plants which have medicinal properties including dadap (Erythrina orientalis). This study aims to utilized dadap herbal liniment by modifying heating in Vigin Cocanut Oil. The study conducted in the laboratory of Agricultural Product Processing using a Factorial Completely Randomized Design (CRD). The first factor is the addition of 250 ml (M1), 375 ml (m2), and 400 ml (M3) Virgin Cocanut Oil treatment. The second factor is the heating tim of 5 minutes (L1), 10 minutes (L2), and 15 minutes (L3). Observation variable consisted of yield, Specific gravity, and organoleptic test of aroma and colored. The result showed an average yield of 87.70-91.88%. The highest yield was found in the treatment of adding 400 ml Virgin Cocanut Oil and 15 minutes of heating time. The highest type of weight was found in the treatment of addition of 325 ml Virgin Cocanut Oil and 5 minutes heating time. Based on the organoleptic scent test, the everage penalist gives a like answer. Organoleptic colors of reudeuep herbal products is according to SNI number 06-23-2006.

Mikroalgák mint természetes hatóanyagforrások

2018 ◽  
Vol 159 (18) ◽  
pp. 703-708
Author(s):  
Gábor Vasas
Keyword(s):  
Mass Production ◽  
Higher Plants ◽  
Herbal Medicines ◽  
Point Of View ◽  
Historical Background ◽  
Herbal Products ◽  
Chlorella Sp ◽  
Economic Significance ◽  
Preclinical And Clinical Studies ◽  
Microalgal Species

Abstract: More than 90% of herbal products and herbal medicines have been derived from higher plants recently, but due to independent circumstances, several photosynthetic microalgal species are in focus in this point of view. In the last 50 years, many carbohydrate-, peptide-, terpenoid-, alkaloid- and phenol-type components were described from algae because of the developing structural determination and analytical methods, algae mass production and also artificial algae technologies. At the same time, based partly on traditional causes and partly on the clinical and preclinical data of today, some dried products of algae are directly used as food supplements. Hereinafter, the historical background, economic significance and metabolic background of the mostly used microalgal species will be reviewed. The diverse metabolite production of these organisms will be demonstrated by some molecules with special bioactivity. Several preclinical and clinical studies will be described relating to the microalgal species Spirulina sp., Chlorella sp., Haematococcus sp. and Dunaliella sp. Orv Hetil. 2018; 159(18): 703–708.

Herbal Products for Common Auto-Inflammatory Disorders - Novel Approaches

2018 ◽  
Vol 21 (3) ◽  
pp. 161-174 ◽  
Author(s):  
Shanoo Suroowan ◽  
Fawzi Mahomoodally
Keyword(s):  
Adverse Effects ◽  
Chronic Conditions ◽  
Herbal Medicines ◽  
Review Article ◽  
Herbal Products ◽  
Inflammatory Disorders ◽  
Treatment Regimens ◽  
Synthetic Agents ◽  
Unique Approach ◽  
Novel Approaches

Background: Common auto-inflammatory disorders (CAIDs) constitute a wide array of ailments ranging from acute allergies to chronic conditions. Globally, CAIDs remain one of the leading causes of disability and morbidity. Despite playing a leading therapeutic role, the vast profusion of anti-inflammatory synthetic agents have not been able to fully resolve a panoply of CAIDs. Additionally, contemporary synthetic therapy approaches remain bounded by a wide array of limitations essentially being adverse effects and unaffordable costs. In this advent, the use of herbal products provides an interesting avenue to explore in view of developing such treatment regimens. Objective: This review article endeavors to highlight potential herbal products and isolated phytochemicals which can be of benefit in the prophylaxis, management, and treatment alongside avoiding the relapse of CAIDs. Conclusion: This review article has highlighted that herbals, herbal products, and isolated metabolites hold a huge potential in the prophylaxis, management, and treatment of CAIDs. Herbals can act on various targets involved in the pathogenesis of inflammatory disorders. In addition, novel approaches for the management of CAIDs are numerous. Indeed, nanoparticles loaded with phytochemicals have been developed to specifically target the colon for IBD treatment. In silico approaches using herbals also offer unlimited avenues to decipher new pharmacophores. Investigating the potential of polyherbal formulations is another unique approach which can be investigated. Given the inefficacy of conventional medicines, the concomitant use of conventional and herbal medicines can also be explored.

Ginger and Heart Health: From Mechanisms to Therapeutics

2020 ◽  
Vol 13 ◽  
Author(s):  
Sajad Fakhri ◽  
Jayanta Kumar Patra ◽  
Swagat Kumar Das ◽  
Gitishree Das ◽  
Mohammad Bagher Majnooni ◽  
...  
Keyword(s):  
Side Effects ◽  
Molecular Mechanisms ◽  
Biological Activities ◽  
Health Benefits ◽  
Herbal Medicines ◽  
Cardiovascular Complications ◽  
National Database ◽  
Heart Health ◽  
Natural Entities ◽  
Cardioprotective Effects

Background: As a major cause of morbidity and mortality, cardiovascular diseases (CVDs) are globally increasing. In spite of recent development in the management of cardiovascular complications, CVDs have remained a medical challenge. Numerous conventional drugs are used to play cardioprotective roles; however, they are associated with several side effects. Considering the rich phytochemistry and fewer side effects of herbal medicines, they have gained particular attention to develop novel herbal drugs with cardioprotective potentials. Amongst natural entities, ginger is an extensively used and well-known functional food and condiment, possessing plentiful bioactivities, like antiinflammatory, antioxidant, and antimicrobial properties in several disorders management. Objective: The current review deliberated phytochemical properties as well as the ginger/ginger constituents' biological activities and health benefits in several diseases, with particular attention to cardiovascular complications. Methods: A comprehensive research was conducted using multiple databases, including Scopus, PubMed, Medline, Web of Science, national database (Irandoc and SID), and related articles in terms of the health benefits and cardioprotective effects of ginger/ginger constituents. These data were collected from inception until August 2019. Results: In recent years, several herbal medicines were used to develop new drugs with more potency and also minor side effects. Amongst natural entities, ginger is an extensively used traditional medicine in several diseases. The crude extract, along with related pungent active constituents, is mostly attributed to heart health. The cardioprotective effects of ginger are contributed to its cardiotonic, antihypertensive, anti-hyperlipidemia, and anti-platelet effects. The signaling pathways and molecular mechanisms of ginger regarding its cardioprotective effects are also clarified. Conclusion: This study revealed the biological activities, health benefits, and cardioprotective properties of ginger/ginger constituents along with related mechanisms of action, which gave new insights to show new avenue in the treatment of CVDs.

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