scholarly journals Analysis of regulatory-ethical framework of clinical trials

2013 ◽  
Vol 141 (9-10) ◽  
pp. 659-666 ◽  
Author(s):  
Andrijana Milosevic-Georgiev ◽  
Dusanka Krajnovic ◽  
Srdjan Milovanovic ◽  
Svetlana Ignjatovic ◽  
Dusan Djuric ◽  
...  

Introduction. Every clinical trial has to meet all ethical criteria in addition to the scientific ones. The basic ethical principles in the clinical trials are the following: nonmaleficence, beneficence, respect for autonomy and the principle of justice. Objective. The aim of the study was to analyze clinical cases with the outcomes leading to the changes in regulatory?ethical framework related to the clinical trials, as well as the outcomes of key clinical trials that influenced the introduction of the ethical principles into clinical trials. Methods. This was a descriptive research (methods of analysis and documentation; desk analysis of the secondary data). Results. By analyzing the cases from the secondary sources as well as clinical and ethical outcomes, it may be noticed that the codes, declarations and regulations have been often preceded by certain events that caused their adoption. Moral concern and public awareness of the ethical issues have initiated not only the development of numerous guidelines, codes, and declarations, but also their incorporation into the legislative acts. Conclusion. It is desirable that ethical instruments become legally binding documents, because only in this way will be possible to control all phases of the clinical trials and prevent abuse of the respondents.

2020 ◽  
Vol 26 (5) ◽  
pp. 2867-2891 ◽  
Author(s):  
Dylan Cawthorne ◽  
Aimee Robbins-van Wynsberghe

Abstract The use of drones in public healthcare is suggested as a means to improve efficiency under constrained resources and personnel. This paper begins by framing drones in healthcare as a social experiment where ethical guidelines are needed to protect those impacted while fully realizing the benefits the technology offers. Then we propose an ethical framework to facilitate the design, development, implementation, and assessment of drones used in public healthcare. Given the healthcare context, we structure the framework according to the four bioethics principles: beneficence, non-maleficence, autonomy, and justice, plus a fifth principle from artificial intelligence ethics: explicability. These principles are abstract which makes operationalization a challenge; therefore, we suggest an approach of translation according to a values hierarchy whereby the top-level ethical principles are translated into relevant human values within the domain. The resulting framework is an applied ethics tool that facilitates awareness of relevant ethical issues during the design, development, implementation, and assessment of drones in public healthcare.


2020 ◽  
Vol 3 (2) ◽  
pp. 34-47
Author(s):  
Ananya Mukherjee ◽  
Md. Faisal ◽  
Milton Kumar Saha

Measuring urban resilience is one of the important processes toward understanding the potential current and future risks of cities, assessing the challenges of urbanization and to guide the development of urban areas. The research was conducted in a slum named Bangabandhu Colony under Barishal City Corporation (BCC). The purpose of the research was to measure the urban disaster resilience and to find out a better way of future urban disaster resilience in this area. Climate Disaster Resilience Index (CDRI) was used to measure climate-related disaster resilience by considering five dimensions: physical, social, institutional, economic and natural which shows resilience level ranging from 1-5 where 1 representing very poor and 5 best. A semi-structured questionnaire was used for collecting the primary data and the secondary data was collected from secondary sources. Results revealed that the resilience level of physical, social, institutional, economic, and natural dimensions was 2.76, 2.79, 2.29, 2.53, 2.59 respectively, which indicates a medium resilience level of all dimensions. Finally, the research depicted that, the resilience level of the area will increase through hand to hand working of people with government and non-government officials, conducting public awareness programs, campaigns, seminars and discussions. The findings of the research can be used by researchers and development workers for enhancing disaster resilience of other areas under Barishal City Corporation as well as other city areas of Bangladesh.


2018 ◽  
Vol 38 (05) ◽  
pp. 505-514 ◽  
Author(s):  
Xiaowei Su ◽  
Zachary Simmons

AbstractRecent advances in the genetics of neurologic diseases coupled with improvements in sensitivity and specificity are making genetic testing an increasingly important part of diagnosis and management for neurologists. However, the complex nature of genetic testing, the nuances of multiple result types, and the short- and long-term consequences of genetic diagnoses raise important ethical issues for the clinician. Neurologists must balance the ethical principles of beneficence and nonmaleficence, on the one hand, with patient autonomy on the other hand, when ordering such tests by facilitating shared decision making, carrying out their fiduciary responsibilities to patients, and ensuring that patients have adequate counseling to make informed decisions. This review summarizes ethical issues related to genetic testing for neurologic diseases, with a focus on clinical practice. Informed consent for genetic testing of patients and asymptomatic at-risk family members is discussed. The roles and responsibilities of physicians as genetic counselors are reviewed, including the framing of incidental findings and variants of unknown significance that impact individuals' decisions about whether to pursue genetic testing and what results they wish to know. Disclosure and its consequences for the patient are placed within an ethical framework to permit a better understanding of why genetic testing is different from most other diagnostic testing ordered by physicians. The review ends with clinical vignettes that attempt to place ethical principles into familiar clinical settings involving physicians, patients and their families.


Author(s):  
Jaana Leikas ◽  
Raija Koivisto ◽  
Nadezhda Gotcheva

To gain the potential benefit of autonomous intelligent systems, their design and development need to be aligned with fundamental values and ethical principles. We need new design approaches, methodologies and processes to deploy ethical thought and action in the contexts of autonomous intelligent systems. To open this discussion, this article presents a review of ethical principles in the context of artificial intelligence design, and introduces an ethical framework for designing autonomous intelligent systems. The framework is based on an iterative, multidisciplinary perspective yet a systematic discussion during an Autonomous Intelligent Systems (AIS) design process, and on relevant ethical principles for the concept design of autonomous systems. We propose using scenarios as a tool to capture the essential user’s or stakeholder’s specific qualitative information, which is needed for a systematic analysis of ethical issues in the specific design case.


Author(s):  
Sağbetullah Meriç

Ethics refers to the norms and collectively formed criteria created by a group of people for specific purposes. Ethics is the set of principles that guide a person or group's behaviour, setting the standards of good or bad, right, or wrong. In this section, the issue of ethics in the tourism sector is examined. Secondary sources were used while preparing the chapter. First of all, the place and importance of the tourism sector today and the tourism sector's ethical problems have been stated. The ethical principles determined by the World Tourism Organization were examined by saying that all stakeholders in the tourism sector should adopt and share ethical principles. By stating the problems caused by ethical violations, suggestions for solutions are presented. The necessity of eliminating ethical issues was expressed with the recommendations that set the groundwork for future research in this field. Finally, the general scope and results of the chapter are presented and discussed.


2016 ◽  
Vol 4 (2) ◽  
pp. 34 ◽  
Author(s):  
Nuruddeen Abba Abdullahi

The Nigerian banking reform precipitated the adoption of Islamic banking and finance in 2009 as additional door to banking mechanism in the country. However, the implementation of the Islamic banking or non-interest banking has generated a lot of debate, specifically because its foundations are based on Islamic religion. This paper briefly reviews the concept, the challenges and prospects of Islamic banking in Nigeria. The paper relies on the secondary sources by reviewing and analysing various works on the subject. A reflection on the size of its population and the developmental opportunities indicates that Nigeria has the prospect of becoming the hub centre of Islamic finance in Africa. Yet there are numerous challenges to the development of the Islamic banking system in the country, including misrepresentation of the system, lack of linkages and investment institutions, lack of adequate knowledge, as well as shroud business ethos and corruption, which is endemic in the country. The paper recommends the need for greater public awareness about Islamic banking and creation of enabling environment (i.e. the legal, accounting and taxation systems) for the working of Islamic financial system.   


2019 ◽  
Vol 118 (11) ◽  
pp. 603-618
Author(s):  
ZawZawMyint ◽  
Sandeep Poddar ◽  
Abhijit Ghosh ◽  
Amiya Bhaumik

In banking industries, employees are entrusted with different roles and responsibilities, and training enables them to carry out these roles and responsibilities efficiently by let them to learn new things. Moreover, it will prepare them to take up higher responsibilities in the future. Therefore, this study focuses to analyze the employee perceptions on effectiveness of Training Programs in Myanmar Citizens Bank (MCB).  By using the descriptive research method, primary data are collected from the responsible persons and employees of MCB in head office, branches. Secondary data are gathered and scrutinized from relevant text books, records and annual reports from MCB. The research revealed that there are four kinds of training programs in MCB. Moreover, this paper revealed that MCB successfully delivered its training programs in year 2015 to 2018 and the trainees have positive perceptions on effectiveness of training programs in MCB. Based on these results, this paper pointed out the important facts that can give improvement actions for effective and efficient training programs in Myanmar Citizen Banks.


2016 ◽  
Vol 3 (01) ◽  
Author(s):  
Rakesh Rangwani

Despite substantial improvements over the past 23 years in many key areas of sustainable development, the world is not on track to achieve the goals as aspired to in Agenda 21, adopted in Rio de Janeiro in 1992, and reiterated in subsequent world conferences, such as the World Summit on Sustainable Development held in Johannesburg in 2002. While there have been some achievements in implementing Agenda 21, including the implementation of the chapters on “Science for Sustainable Development” and on “Promoting Education, Public Awareness and Training”, for which UNESCO was designated as the lead agency, much still remains to be done. This decade had seen the idea of a “green economy” float out of its specialist moorings in environmental economics and into the mainstream of policy discourse. It is found increasingly in the words of heads of state and finance ministers, in the text of G20 communiqués, and discussed in the context of sustainable development and poverty eradication. The research paper focused to establish a relationship between sustainable development and green economics. The research paper is descriptive and analytical in nature. The data collected from secondary sources such as report from niti aayog, IMF indicators, RBI reports, newspapers, journals. The research design was adopted to have greater accuracy and in depth analysis of the research study. The statistical tools for the analysis are also being used.


Author(s):  
Saikat Gochhait

Businesses work in a wide social environment in which they have a responsibility to a range of stakeholders including the community. The term Corporate Social Responsibility (CSR) refers to the responsibility that modern business organizations have to creating a healthy and prosperous society. Ethical practices in refractory marketing help marketers distinguish between right and wrong behavior. Adherence to ethics is essential in industrial markets as mutual trust among buyers and sellers is the key to long-term success. Marketing has evolved from a production-centric approach to a societal marketing approach that lays greater emphasis on the ethical issues in marketing. With the advent of globalization, corporations continue to evolve, grow in power, and influence the process of consolidation. Corporations are in positions of power that allow them to do greater damage to others when they act unethically or socially in an irresponsible manner. The rights theory encompasses a variety of ethical philosophies holding that certain human rights are fundamental and must be respected by other humans. The economic theories of the firm cannot be segregated of ethical considerations as they have crucial impact on how the firm concentrates on economic power, formulate the rules of law. Profit maximisation has always been the driving force and an undercurrent behind the development of corporate. But profit is not made in vacuum, it always has an associated cost, some of which is always externalized (Rhee, 2008). Corporate law has an ethical foundation and the debate on values necessarily revolves round the activities of the firm. This research paper on the basis of secondary sources of data collected from reports, research papers and Internet, focuses on corporate social responsibility (CSR) of TATA Group with reference to Tata Krosaki Refractories Ltd, Bajoria Group with reference to IFGL Refractories Ltd (Odisha), OCL Refractories Ltd, Sarvesh Refractories, and Manishree Refractories (Odisha). The study intends to understand the scope of corporate social responsibility and get an insight in CSR and ethical practices in the light of the case study of the refractory industries in Odisha.


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