scholarly journals Untreated Inactive Pulmonary Tuberculosis: Risk of Reactivation

1962 ◽  
Vol 77 (6) ◽  
pp. 461 ◽  
Author(s):  
George W. Comstock
Keyword(s):  
Pulmonary Tuberculosis ◽  
Tuberculosis Risk

scholarly journals A CROSS SECTIONAL STUDY ON KNOWLEDGE OF TUBERCULOISIS AMONG RURAL AND URBAN POPULATION OF UDAIPUR DISTRICT, RAJASTHAN

2020 ◽  
pp. 1-2
Author(s):  
Ganesh Salvi ◽  
Rakhi Luthra
Keyword(s):  
Risk Factors ◽  
Pulmonary Tuberculosis ◽  
Urban Population ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Duration Of Treatment ◽  
Cross Sectional ◽  
Rural And Urban ◽  
Tuberculosis Risk

AIM: To assess the knowledge regarding Tuberculosis cause, spread, types and duration of treatment among rural and urban population of Udaipur, Rajasthan. Methodology: A cross sectional study was conducted during January to March 2020 in OPD’s of PHC and UHC of Udaipur city. Total of 216 participants were included. Results: Our study showed that 30.09% were believed that Tb spread form Air, 42.22% were aware about Pulmonary tuberculosis and 53.24% were know that treatment of Tb lasts for 6 months. Conclusion: There is a need to aware people more about Tuberculosis risk factors, symptoms and treatment.

scholarly journals Faktor Risiko Tuberculosis Paru di Kabupaten Rejang Lebong

2007 ◽  
Vol 2 (3) ◽  
pp. 112
Author(s):  
Demsa Simbolon
Keyword(s):  
Risk Factor ◽  
Pulmonary Tuberculosis ◽  
Case Control Study ◽  
Smoking Behavior ◽  
Dominant Factor ◽  
Exclusion Criteria ◽  
Housing Environment ◽  
Source Of Infection ◽  
Control Study ◽  
Tuberculosis Risk

Di Kabupaten Rejang Lebong, sejak tahun 1995 telah dilaksanakan kegiatan pemberantasan TB Paru dengan strategi DOTS, tetapi penderita baru tetap di temukan dan memperlihatkan trend yang meningkat dari tahun ke tahun. Penelitian ini bertujuan untuk mengetahui faktor risiko yang berhubungan dengan kejadian TB paru BTA (+) di Kabupaten Rejang Lebong. Desain penelitian yang digunakan aalah disain kasus kontrol. Kelompok kasus adalah penderita TB Paru BTA (+) berumur ³15 tahun yang berobat pada Oktober 2005 sampai Mei 2006. Kontrol adalah tetangga kasus yang tidak mempunyai tanda-tanda gejala klinis TB paru dengan golongan umur ³15 tahun. Jumlah sampel sebanyak 50 kasus dan 50 kontrol dengan teknik stratified Random Sampling. Analisis data menggunakan metode regresi logistik ganda. Hasil penelitian menemukan bahwa faktor risiko kejadian TB Paru jika tidak pernah di imunisasi BCG (OR=2,855, P=0,048), ada sumber kontak (OR=2,263, P=0,046), luas ventilasi rumah kurang dari 10% luas lantai (OR=4,907, P=0,004), tidak ada cahaya matahari masuk ke rumah (OR=5,008, P=0,006), interaksi antara perilaku merokok dengan penghuni rumah padat serta keeratan kontak (OR=14,576, P=0,017). Faktor yang paling dominan adalah interaksi perilaku merokok dan penghuni rumah yang padat. Probabilitas seseorang mengalami TB paru denganfaktor risiko adalah 98%.Kata kunci: TBC, faktor risiko, sumber penular, lingkunganAbstractSince 1995, eradication program of Pulmonary Tuberculosis with strategy of DOTS have been executed in Rejang Lebong District, but new patient remain to occur and showing tendency of increasing from year to year. The objective of this study is to know risk factor related to occurence of Pulmonary Tuberculosis BTA (+) in Rejang Lebong District. This research use case control study with comparison 1:1. Case is patient of Pulmonary Tuberculosis BTA (+) residing in working areas of Puskesmas Curup, Perumnas and Puskesmas Kampung Delima age >15 year, who seek medical treatment within October 2005 to May 2006, with exclusion criteria of not being relapsing TB patient. Control is neighbor of case who don’t have symptom of clinical Pulmonary Tuberculosis of the same age with cases. Research was conducted in May-July 2006 with 50 cases and 50 controls. Data analysis used in this study is multivariate logistic regression. The study has found that risk factor related to occurrence of Pulmonary Tuberculosis is not BCG immunized (OR=2.855, p=0.048), source of infection (OR=2.263, p=0.046), ventilation less than 10% of wide floor (OR=4.907, p=0.004), no sunlight into the house (OR=5.008, p=0.006), interaction between smoking behavior with house density, and closeness of contact (OR=14.576, P=0.017). The most dominant factor is interaction between smoking behavior with house density.Keywords : Pulmonary tuberculosis, risk factors, source of infection, housing environment

scholarly journals Associations of genetic variants of miRNA coding regions with pulmonary tuberculosis risk in China

2021 ◽  
pp. 1-19
Author(s):  
Mingwu Zhang ◽  
Zhengwei Liu ◽  
Yelei Zhu ◽  
Songhua Chen ◽  
Bin Chen ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Genetic Variants ◽  
Coding Regions ◽  
Tuberculosis Risk

scholarly journals Faktor Risiko Tuberkulosis Paru pada Masyarakat di Wilayah Kerja Puskesmas Bambu Apus Kota Tangerang Selatan

2019 ◽  
Vol 3 (2) ◽  
pp. 112-117
Author(s):  
Rony Darmawansyah Alnur ◽  
Rismawati Pangestika
Keyword(s):  
Risk Factors ◽  
Pulmonary Tuberculosis ◽  
Health Center ◽  
Chi Square ◽  
Bivariate Data ◽  
Work Area ◽  
Chi Square Test ◽  
And Control ◽  
Control Study ◽  
Tuberculosis Risk

ABSTRACT Pulmonary tuberculosis is a contagious disease that is still a problem in the world of health until now. Pulmonary tuberculosis attacks the lungs caused by Mycrobacterium tuberculosis. Indonesia is included in a country with a high burden of tuberculosis, ranking 4th as a contributor to tuberculosis after India, China and South Africa.This study aims to determine internal risk factors that can cause pulmonary tuberculosis in the Dhuafa population. This type of research is analytical with a case control Study. The sample study was divided into case and control samples totaling 30 people with pulmonary tuberculosis and 30 people non-pulmonary tuberculosis. Univariate data were analyzed descriptively and bivariate data were analyzed by Chi-Square test with a 95% confidence level. The results of this studied showed that the risk factors that was the caused of the incidence of pulmonary tuberculosis in the work area of ​​Bambu Apus Health Center were a household contact with patient pulmonary tuberculosis. (OR: 3.5; 95% CI: 1.112-11,017; p = 0.028) and habit of smoking family at home (OR: 4,333; 95% CI: 1,203-15,605; p = 0,020). The education level and occupancy density were variables that have no relationship with the incidence of pulmonary tuberculosis in the work area of ​​Bambu Apus Health Center. Keywords: Pulmonary Tuberculosis, Risk Factors, Dhuafa

scholarly journals A reappraised meta-analysis of the genetic association between vitamin D receptor BsmI (rs1544410) polymorphism and pulmonary tuberculosis risk

2017 ◽  
Vol 37 (3) ◽  
Author(s):  
Mohammed Y. Areeshi ◽  
Raju K. Mandal ◽  
Sajad A. Dar ◽  
Abdulrahman M. Alshahrani ◽  
Aqeel Ahmad ◽  
...  
Keyword(s):  
Vitamin D ◽  
Pulmonary Tuberculosis ◽  
Vitamin D Receptor ◽  
Meta Analysis ◽  
Genetic Models ◽  
Wild Type ◽  
Vdr Gene ◽  
Bsmi Polymorphism ◽  
Increased Risk ◽  
Tuberculosis Risk

BsmI (rs1544410) polymorphism located in intron 8 at the 3′-end of the vitamin D receptor (VDR) gene is known to be involved in the regulation of mRNA stability. Many studies evaluated the possible correlation between VDR BsmI polymorphism and the risk of pulmonary tuberculosis (PTB), and reported conflicting results. In the present study, an updated meta-analysis was performed to evaluate the above-said association. PubMed, Embase, and Google Scholar web-databases were searched for the relevant studies and a meta-analysis was performed by calculating pooled odds ratios (ORs) and 95% confidence intervals (95% CIs) for all the genetic models. A total of 19 studies comprising 3644 controls and 2635 cases were included in the present study. Overall no association of PTB in allelic contrast (b compared with B: P=0.285; OR =0.909, 95% CI =0.762–1.083), homozygous (bb compared with BB: P=0.881; OR =0.975, 95% CI =0.700–1.359), heterozygous (bB compared with BB: P=0.834; OR =1.017, 95% CI =0.872–1.185), dominant (bb compared with BB + Bb: P=0.451; OR =0.954, 95% CI =0.843–1.079) and recessive (bb + Bb compared with BB: P=0.983; OR =1.002, 95% CI =0.868–1.156) genetic models in comparison with wild-type allele and genotype BB were observed. However, variant allele (b compared with B: P=0.001; OR =2.289, 95% CI =1.661–3.154) showed increased risk of PTB in Asians. In conclusion, VDR BsmI polymorphism is not a risk factor for PTB in overall population. However, this polymorphism may be interrelated to an increased risk of PTB amongst Asians.

scholarly journals Associations of genetic variants at TAP1 and TAP2 with pulmonary tuberculosis risk among the Chinese population

2021 ◽  
Vol 149 ◽  
Author(s):  
Mingwu Zhang ◽  
Xiaomeng Wang ◽  
Yelei Zhu ◽  
Songhua Chen ◽  
Bin Chen ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Antigen Processing ◽  
Haplotype Analysis ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Genetic Predictor ◽  
Common Infectious Disease ◽  
Spss Software ◽  
Control Study ◽  
Tuberculosis Risk

Abstract Tuberculosis (TB) is a common infectious disease, and the present study aims to explore the associations of single nucleotide polymorphisms (SNPs) at rs1135216 and rs1057141 of transporter-associated antigen processing (TAP1) and rs2228396 of TAP2 with pulmonary tuberculosis (PTB) risk. A case–control study including 168 smear-positive PTB cases and 251 controls was conducted. Genotyping of the SNPs at rs1135216, rs1057141 and rs2228396 was performed, and their associations with PTB risk were analysed with SPSS software version 19.0. After conducting stratification for age, a significant association was detected for rs1057141 with increased PTB risk (OR = 0.17, 95% CI 0.04–0.79) among those aged ≥60 years. For those aged <60 years, a marginally significant association was detected between rs1135216 TC/CC and PTB risk (OR = 1.97, 95% CI 0.93–4.19). Haplotype analysis revealed that the haplotype AT at rs1135216 and rs2228396, as well as AAT at rs1057141, rs1135216 and rs2228396, was associated with increased PTB risk, and the ORs were 2.83 (95% CI 1.30–6.14) and 2.89 (95% CI 1.34–6.27), respectively. Rs1057141 is a genetic predictor of reduced PTB risk for those aged ≥60 years, while rs1135216 might be a potential genetic predictor for those aged <60 years. Haplotype AT at rs1135216 and rs2228396, as well as AAT at rs1057141, rs1135216 and rs2228396, is a genetic marker that may predict PTB risk.

scholarly journals Extrapulmonary tuberculosis: risk factors

2021 ◽  
Vol 18 (4) ◽  
pp. 48-54
Author(s):  
M. A. Yudenko ◽  
I. V. Buinevich ◽  
D. Y. Rusanau ◽  
S. V. Goponiako
Keyword(s):  
Risk Factors ◽  
Retrospective Study ◽  
Pulmonary Tuberculosis ◽  
Older Persons ◽  
Extrapulmonary Tuberculosis ◽  
Significant Risk ◽  
High Index ◽  
Clinical Risk Factors ◽  
High Index Of Suspicion ◽  
Tuberculosis Risk

Objective. To identify the main demographic and clinical risk factors for the development of extrapulmonary tuberculosis (EPTB).Materials and methods. A retrospective study of tuberculosis cases registered from 2016 to 2020 in the Gomel region was conducted (330 patients with EPTB and 2,505 patients with pulmonary tuberculosis). The odds ratios were calculated to assess the risk factors for the development of EPTB.Results. The prevalence of EPTB was studied over the course of five years. The most significant risk factors for the development of tuberculosis in extrapulmonary localizations have been identified.Conclusion. The risk factors for the development of EPTB are age (EPTB often develops in children and older persons), females, and in those who have had an episode of tuberculosis previously. Awareness of the predisposing factors may help physicians maintain a high index of suspicion regarding the development of EPTB.

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