scholarly journals The Investment Attractiveness of Regions as One of Entrepreneurship Development Factors

2020 ◽  
Vol 13 (2) ◽  
pp. 170-183
Author(s):  
Izabella Sikorska-Wolak ◽  
Jan Zawadka ◽  
Krystyna Krzyżanowska
Keyword(s):  
Survival Rate ◽  
Considerable Influence ◽  
Enterprise Development ◽  
Entrepreneurship Development ◽  
The Subject ◽  
Using Data ◽  
One Year ◽  
The One ◽  
Desk Research ◽  
Market Economics

SummarySubject and purpose of work: The subject of the paper is entrepreneurship development and its determinants, with particular attention to the investment attractiveness of Polish provinces. The purpose of the paper is to identify the level of entrepreneurship development (between 2009 and 2017) and investment attractiveness (between 2009 and 2016) of individual provinces, and to define the correlation between the two features.Materials and methods: The authors of this paper analysed the literature on the subject and performed desk research using data from reports and studies published by GUS (Statistics Poland), PAPR (Polish Agency for Enterprise Development) and IBnGR (Gdańsk Institute for Market Economics).Results: In 2017, the number of SMEs* in Poland increased by over 24% in relation to 2009. The results showed a significant inversely proportional correlation between the number of enterprises per 1000 inhabitants and the one-year survival rate for the enterprises. The investment attractiveness of provinces was diverse. The level of investment attractiveness exerted a considerable influence on enterprise development in individual provinces.Conclusions: The results of the study showed that both the investment attractiveness and entrepreneurship are diverse in individual regions. A significant correlation was found between these two phenomena. Some exceptions to the rule were identified, which can be explained by divergence.

Renal Transplantation—A Tale of Two Cities

1980 ◽  
Vol 25 (4) ◽  
pp. 269-274
Author(s):  
R. F. M. Wood ◽  
P. R. F. Bell ◽  
J. Walls ◽  
J. R. Nash ◽  
D. S. MacPherson ◽  
...  
Keyword(s):  
Renal Transplantation ◽  
Survival Rate ◽  
Graft Survival ◽  
Initial Experience ◽  
Tissue Typing ◽  
Two Cities ◽  
Transplant Team ◽  
The Difference ◽  
One Year ◽  
The One

In 1974 three members of the transplant team from the Western Infirmary in Glasgow moved to the new medical school in Leicester. The initial experience with 33 patients transplanted in Glasgow was published in 1972 and this paper compares the results of that series with the first 21 patients grafted in Leicester. Despite improvements in tissue typing, better quality donor kidneys and fewer complications, there has been a failure to improve on the levels of graft survival. The overall one year graft survival rate in the Glasgow series was 79 per cent compared to 52 per cent in Leicester. In these two series the difference in results appears to be explained by blood transfusion. All the Glasgow patients had been poly-transfused but of the Leicester patients the 10 transfused pre-transplant had a one year graft survival of 90 per cent while in the 11 non-transfused patients the one year graft survival was only 18 per cent.

Gemcitabine, oxaliplatin and weekly high-dose 5-FU as a 24-hr-infusion in chemonaive patients with advanced or metastatic carcinoma of the gallbladder: Preliminary results of a multicenter phase II-study

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 4129-4129 ◽  
Author(s):  
A. D. Wagner ◽  
P. Buechner-Steudel ◽  
H. Schmalenberg ◽  
M. Moehler ◽  
O. Kuss ◽  
...  
Keyword(s):  
Survival Rate ◽  
Median Survival ◽  
Phase Ii ◽  
Tumor Response ◽  
Phase Ii Study ◽  
Metastatic Carcinoma ◽  
Phase Iii ◽  
Carcinoma Of The Gallbladder ◽  
One Year ◽  
The One

4129 Background: Combinations of gemcitabine (GEM)/5-FU, GEM/oxaliplatin (LOHP) or 5-FU/LOHP work synergistically in pancreatic and/or colorectal malignancies, and have non-overlapping safety profiles. This phase II-study was designed to evaluate the efficacy and safety of the triple combination GEM/LOHP/5-FU in patients (pts) with advanced or metastatic carcinoma of the gallbladder. Methods: One-stage, multicentre phase II study. Eligibility criteria: chemonaive pts with histologically proven advanced, recurrent or metastatic gallbladder carcinoma (ECOG 0–1; expected survival >3 months; measurable disease; adequate renal, hepatic and bone marrow function). According to the results of our previous phase I-study (Proc ASCO 2003, # 1298), pts were treated with GEM 900mg/m2 as a 30-min infusion, followed by LOHP 65 mg/m2 (2-hr infusion) after a 30 min rest and 5-FU 1500 mg/m2 (24-hr-infusion) on d 1, 8, every 3 weeks. Planned sample size: 35 response evaluable patients. The primary endpoint was tumor response, secondary endpoints were toxicity, median survival, the one-year-survival rate, clinical benefit and quality of life. Results: At time of abstract submission, median follow-up of 35 enrolled pts is 9.8 months. Pt. characteristics: m/f: 11/24, median age 61 (range 42–81), ECOG 0/1: 24/11 (69/31%) pts, locally advanced/metastatic disease 1/32 (3/91%) pts. Analysis of tumor response is still pending. Grade III/IV (NCI-CTC) toxicities occurred in 36/3% of 191 cycles and were: leucopenia 3/1%, neutropenia 4/1%, thrombocytopenia 4/1%, anemia 2/0%, nausea 1/0%, sensory neuropathy 4/0%, asthenia 1/0%, elevated bilirubin 2/0%, AP 4/0%, or elevated SGOT/SGPT 1/0%, edema 1/0%, infection 1/0%, dyspnoe 1/1%. Median survival of all pts is 9.9 months (95% CI: 7.5–11.5), the one-year-survival-rate is 30 % (95% CI: 16–47). Conclusions: GEM/LOHP/5-FU combination therapy is tolerated well in patients with gallbladder cancer. The promising survival data has to be confirmed in a phase III study. (Supported by grants from Eli Lilly and Company, Indianapolis, IN, USA and Sanofi-Synthelabo, Paris, France). [Table: see text]

scholarly journals Explainable models for forecasting the emergence of political instability

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0254350
Author(s):  
Emma Baillie ◽  
Piers D. L. Howe ◽  
Andrew Perfors ◽  
Tim Miller ◽  
Yoshihisa Kashima ◽  
...  
Keyword(s):  
Predictive Power ◽  
Task Force ◽  
Political Instability ◽  
Lasso Regression ◽  
Macroeconomic Factors ◽  
Policy Makers ◽  
Public Data ◽  
Using Data ◽  
One Year ◽  
The One

Building on previous research on the use of macroeconomic factors for conflict prediction and using data on political instability provided by the Political Instability Task Force, this article proposes two minimal forecasting models of political instability optimised to have the greatest possible predictive power for one-year and two-year event horizons, while still making predictions that are fully explainable. Both models employ logistic regression and use just three predictors: polity code (a measure of government type), infant mortality, and years of stability (i.e., years since the last instability event). These models make predictions for 176 countries on a country-year basis and achieve AUPRC’s of 0.108 and 0.115 for the one-year and two-year models respectively. They use public data with ongoing availability so are readily reproducible. They use Monte Carlo simulations to construct confidence intervals for their predictions and are validated by testing their predictions for a set of reference years separate from the set of reference years used to train them. This validation shows that the models are not overfitted but suggests that some of the previous models in the literature may have been. The models developed in this article are able to explain their predictions by showing, for a given prediction, which predictors were the most influential and by using counterfactuals to show how the predictions would have been altered had these predictors taken different values. These models are compared to models created by lasso regression and it is shown that they have at least as good predictive power but that their predictions can be more readily explained. Because policy makers are more likely to be influenced by models whose predictions can explained, the more interpretable a model is the more likely it is to influence policy.

scholarly journals Analysis of Risk Factors for Carbapenem-Resistant Klebsiella pneumoniae Infection and Its Effect on the Outcome of Early Infection After Kidney Transplantation

2021 ◽  
Vol 11 ◽  
Author(s):  
Fei Zhang ◽  
Jinbiao Zhong ◽  
Handong Ding ◽  
Jiashan Pan ◽  
Jing Yang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Survival Rate ◽  
Klebsiella Pneumoniae ◽  
Postoperative Mortality ◽  
Effective Prevention ◽  
Carbapenem Resistant ◽  
Kaplan Meier ◽  
Total Prevalence ◽  
One Year ◽  
The One

BackgroundInfections remain a major cause of morbidity and mortality in kidney transplant (KT) recipients. This study was performed to identify the overall prevalence of early infections, prevalence of carbapenem-resistant Klebsiella pneumoniae (CRKP) infection after KT, one-year postoperative mortality in patients with early infections and risk factors for CRKP infections.MethodsWe conducted a retrospective study of all patients who received KT in our hospital between January 2017 and December 2019. We evaluated the demographic, clinical, infection characteristics and the one-year postoperative outcomes.ResultsAmong the 419 patients who received KT between January 2017 and December 2019, 150 patients had at least one infection within 90 days after KT. The total prevalence of early infections was 36.1% (150/415), the prevalence of early CRKP infections was 10.4% (43/415), and the one-year postoperative mortality was 15.3% (23/150) in patients with early infections. The risk factors independently related to one-year postoperative mortality were mechanical ventilation (MV) > 48 h (Odds ratio (OR)= 13.879, 95%Confidence interval (CI): 2.265~85.035; P=0.004) and CRKP infection (OR=6.751, 95% CI: 1.051~43.369; P =0.044). MV> 48 h was independently related to CRKP infection (OR=3.719, 95% CI: 1.024~13.504; P=0.046). Kaplan-Meier survival curves showed that the one-year survival rate of patients infected with CRKP in the early postoperative stage was significantly lower than that of uninfected patients.ConclusionsIn general, the prevalence of early infections after KT is high, and CRKP infection is closely correlated with poor prognosis. The effective prevention and treatment of CRKP infection is an important way to improve the one-year survival rate after KT.

scholarly journals Establishment of white poplar clonal plantations by stools

Topola ◽  
2021 ◽  
pp. 11-20
Author(s):  
Branislav Kovačević ◽  
Duško Bastajić ◽  
Slađana Dabić ◽  
Zoran Novčić ◽  
Zoran Galić ◽  
...  
Keyword(s):  
Survival Rate ◽  
Deep Level ◽  
Underground Water ◽  
High Survival ◽  
White Poplar ◽  
Rooted Cuttings ◽  
Clonal Plantation ◽  
Poplar Plantations ◽  
One Year ◽  
The One

The results of white poplar clonal plantation establishment by stools are presented. The trials were established at three sites, characterized by favorable water regime for growth and development of poplars. Also, the effect of different factors on survival rate, diameter at breast height and plants' height was analyzed. Results suggest that similar high survival rate (90-100%) was achieved by planting of stools on depth of 2.5 m (deep planting), as it was achieved by planting of rooted cuttings at the depth of 0.8 m, which is a comon practise in the establishment of white poplar plantations. The survival rate of planted stools did not decrease signifficantly between the end of the first and second growing season. Selected clones achieved survival rate of Villafranca clone with both methods of planting. Two-year old rootless shoots (2/0 type of plantings) achieved higher survival rate than the one-year old ones (1/0 type) and two-year old rooted cuttings (2/2 type). Survival rate of one-year old rootless shoots (1/0 type) planted at the depth of 0.8 m was not significantly lower than of those planted at the depth of 2.5 m, but it was notably lower than survival rate of rooted cuttings (1/1 type). Establishment of white poplar clones by stools could significantly improve white poplar wood production, considering the benefits of plants production in stool beds. The potential for improvement of the establishment of white poplar plantations on sandy soils with relatively deep level of underground water, and the potential for successful planting of difficult-to-root white poplar genotypes, should be the subject of further studies.

A multicenter phase II study of S-1 plus ramucirumab as first-line treatment in elderly patients with advanced/recurrent gastric cancer (KSCC1701).

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 4043-4043
Author(s):  
Hiroo Katsuya ◽  
Koichi Suyama ◽  
Kazuma Kobayashi ◽  
Naoki Izawa ◽  
Yoshikazu Uenosono ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Survival Rate ◽  
Elderly Patients ◽  
Line Treatment ◽  
Efficacy And Safety ◽  
First Line ◽  
Recurrent Gastric Cancer ◽  
One Year ◽  
The One ◽  
First Line Treatment

4043 Background: Elderly patients are often intolerable in the combination with cytotoxic agents. Therapy with S-1 alone is a key option for initial chemotherapy for Japanese elderly patients with unresectable gastric cancer in clinical practice. However, there are some cases in which the antitumor effects with S-1 alone are insufficient. We aimed to investigate the efficacy and safety of S-1 plus ramucirumab therapy to elderly patients with advanced/recurrent gastric cancer. Methods: Patients aged 70 years and older with previously untreated unresectable or recurrent gastric cancer patients were included in Japan. They received S-1 therapy (40-60 mg twice daily for 28 days, every 6 weeks) plus ramucirumab therapy (8 mg/kg, every 2 weeks) until disease progression. The primary endpoint was the one-year survival rate and null hypothesis of one-year survival was set as 40%, which is the lower bound of the 95% confidence interval in previously reported studies on S-1 therapy. The secondary endpoints included progression-free survival (PFS), overall survival (OS), response rate (RR), and safety. Results: Between September 2017 and November 2019, 48 patients were enrolled in this study. The characteristics of patients were male/female: 34/14, median age: 77.5 years (range: 71-87), and PS (0/1): 20/28. The one-year survival rate was 65.2% (95% confidence interval 49.8-78.6%), which means this trial met the primary endpoint. The median OS and PFS were 16.4 months (95%CI:12.0–20.7) and 5.8 months (95%CI:4.0–7.2), respectively. The best RR (CR+PR) was 60.9%. The frequent grade 3 or grade 4 adverse events were neutropenia (27.7%), anorexia (23.4%), anemia (19.1%), hypertension (14.9%), leucopenia (12.8%) and hypoalbuminemia (12.8%). Conclusions: Based on the observed efficacy and safety, S-1 plus ramucirumab is an appropriate first-line treatment for elderly patients with advanced/recurrent gastric cancer. Clinical trial information: UMIN000028309.

scholarly journals Sinkronisasi Ekonomi Pancasila Dan Ekonomi Islam

2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Muhammad Ali Akbar ◽  
Moh. Idil Ghufron
Keyword(s):  
Social Justice ◽  
Content Analysis ◽  
Social Equality ◽  
Library Research ◽  
Data Content ◽  
The Subject ◽  
Using Data ◽  
The One ◽  
Holy Book

AbstractThis study discusses the concept of Pancasila economics and Islamiceconomics which have basic and not conflicting similarities. Both of theseeconomic concepts share the goal of realizing social justice for allIndonesian people and social equality in prosperity and prosperity asstated in the five precepts of the Pancasila, as well as imbued with the firstprinciple of the One Godhead Pancasila as its basis.In this study also explained that between the Pancasila economicconcepts and Islamic economics are two economic concepts whose basicprinciples, characteristics and systems are in accordance with theteachings in the Qur'an which is the holy book of Muslims. So that this canstrengthen the confidence of the Indonesian people to not hesitate toimplement the Pancasila economy which is the noble heritage of thefounding fathers of the nation.The method used in this study is library research, which refers to primalmaterials from two components which are the subject of discussion,namely the study of Pancasila economics and Islamic economics. Andadded with other books relating to the problems studied. While the writingmethod used is descriptive analytical, namely by collecting actualinformation in detail and thoroughly from the data obtained, to thendescribe the exact problem under study, then analyze it directly to becompiled as needed in this study by using data content analysis analysis.Kata Kunci: Ekonomi, Pancasila, Islam, Al-Qur‟an, Keadilan,Kesejahteraan.

scholarly journals An Analysis of Grammatical Errors Committed by the Tenth Grade Students of SMA Negeri 1 Baturiti in Writing Recount Text in Academic Year 2014/2015

2018 ◽  
Vol 23 (2) ◽  
pp. 47
Author(s):  
L A Purnayatri ◽  
I Ketut Seken ◽  
L D.S. Adnyani
Keyword(s):  
Document Analysis ◽  
Analysis Theory ◽  
Grammatical Errors ◽  
Interview Guide ◽  
Combination Of Theories ◽  
Tenth Grade ◽  
The Subject ◽  
Using Data ◽  
The One ◽  
Academic Year

The present study aimed at 1) finding the types of grammatical errors committed by the tenth grade students of SMA Negeri 1 Baturiti in writing recount text in academic year 2014/2015; and 2) finding the sources of the errors committed by the tenth grade students of SMA Negeri 1 Baturiti in writing recount text in academic year 2014/2015. This study was designed as descriptive-qualitative study. The methods used to collectdata were document analysis and interview. The instruments used were project and interview guide. The data in this study were analyzed by using data analysis theory proposed by Miles and Hubarman. The types of grammatical errors used in this study were based on the surface strategy taxonomy proposed by Dulayat alwhile the sources of the errors were based on the combination of theories proposed by Richards and Brown. Model of error analysis used in this study was the one proposed by Gass and Selinker. The result of the study showed that the subject committed 167 errors in their writing, namely misformation (29.94%), addition (27.54%), omission (24.55%), and misordering (17.96%).

scholarly journals Influencers as Support for Public Relations Campaigns

2019 ◽  
Vol 31 (1) ◽  
pp. 131-150
Author(s):  
Dariusz Tworzydło ◽  
Norbert Życzyński ◽  
Marek Wajda
Keyword(s):  
Public Relations ◽  
Research Method ◽  
Qualitative Method ◽  
Direct Impact ◽  
Target Groups ◽  
The Public ◽  
The Subject ◽  
Promotional Campaign ◽  
The One ◽  
Desk Research

Summary The article is a collection of analyses carried out on the basis of literature on the subject and data collected with the utilization of desk research method. It also presents conclusions from surveys conducted by means of a qualitative method — IDI technique — during the Congress of Public Relations Professionals, which took place in April 2018 in Rzeszów. In the group of respondents there were representatives of public relations branch who cooperate with influencers and on top of that have rich experience in the area of PR activities conducted by means of the Internet. The goal of this article is assessment of the relationships occurring in the context of cooperation of PR specialists with influencers, as well as identifying the prospects for changes and potential trends in this area. Among the key conclusions drawn in course of the conducted research we find the one which suggests that using influencers for communication and promotion-related activities is recognized as both a chance and threat for the public relations industry. However, the aspect of threats is particularly important, as it has a direct impact on the emerging and persisting image crises. Due to the fact that influencers enjoy a lot of freedom in their activity in combination with the faith of their clients in their professional approach, there is a risk of emergence of actions which will not just fail to satisfy the assumptions of a promotional campaign, but may also directly hit the image of a given entity. Experts predict that using influencers for promotion will also in the nearest time be a growing trend, which will take hold among solutions used in communication with target groups.

scholarly journals Y-shaped Ventriculo-peritoneal Shunt for Adult Complicated Hydrocephalus: Report of 28 Illustrative Cases

2020 ◽  
Author(s):  
Xiaohui Ren ◽  
Chuanwei Yang ◽  
Xiangrong Li ◽  
Yonggang Wang ◽  
Song Lin
Keyword(s):  
Survival Rate ◽  
Cox Regression ◽  
Tumor Resection ◽  
Long Term Outcome ◽  
Frontal Horn ◽  
First Choice ◽  
Multiloculated Hydrocephalus ◽  
One Year ◽  
The One ◽  
Ventriculo Peritoneal Shunt

Abstract ObjectiveTo investigate the effectiveness of Y-shaped ventriculo-peritoneal shunt (VPS) (one abdominal tip connected with double or triple ventricular tips by one or two Y-shaped connectors) in the treatment of adult complicated hydrocephalus, we analyzed the long-term outcome and reported some illustrative cases.MethodsAmong 1,100 VPS surgeries between 2012 and 2017 in neurosurgery of Beijing Tiantan Hospital, twenty-eight (2.5%) adult patients with multiloculated hydrocephalus treated with Y-shaped shunt were analyzed.ResultsNineteen patients underwent Y-shaped VPS (bilateral frontal horn shunt) before or without tumor resection/stereotactic biopsy, 7 patients underwent Y-shaped VPS after tumor resection (5 bilateral and 2 triple shunts), and the other 2 patients underwent sequential bilateral VPS (unilateral VPS with additional contralateral ventricular tip by Y-shaped connector 6 months later). The one-year and two-year hydrocephalus-free survival rate for was both 88.7%. The one-year and two-year overall survival rate was both 66.7%. Cox regression confirmed that the OS is correlated with tumor grades. ConclusionsY-shaped VPS strategy is an easy and reliable option for multiloculated hydrocephalus, which can be used as the first choice for some indications.

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