scholarly journals REVIEW OF POTENTIAL PLANTS IN INDONESIA AS AN ANTIDIABETIC WITH HYPOGLYCEMIC ACTIVITIES

2021 ◽  
Vol 3 (2) ◽  
pp. 57
Author(s):  
Mutiarani Dasha Hanggaresty ◽  
Ni Kadek Warditiani

Background: Diabetes mellitus which is characterized by hyperglycemia is a metabolic disease due to insulin action, defects in insulin secretion, or both. Various studies have shown that herbs that have a hypoglycemic effect can be used in the treatment of diabetes mellitus. Generally, herbs can slow down the complications of diabetes mellitus and improve metabolism. The ability of plants to restore the function of pancreatic tissue to increase insulin production or make it easier for insulin to process glucose is related to the effects of hypoglycemia. Objective: Comparing plants that have a hypoglycemic activity that can be used in the treatment of diabetes mellitus in Indonesia. Methods: studying literature from various databases, websites, national journals, and relevant international journals to identify plants that have hypoglycemic activity. Results: The mechanism A. sativum as a hypoglycemic involves different fiber viscosities; A. vera involved as a hypoglycemic by protecting pancreatic? cells; Asiatic acid in C. asiatica increasing glycolysis by restoring the activity of key enzymes; G. max inhibiting ?-amylase and the stigmasterol increasing the absorption of blood glucose and reducing insulin resistance; P. macrocarpa exert their antidiabetic action via ?-glucosidase modulation, an extra distinctive pancreatic mechanism; S. arvensis has the potential to inhibit ?-amylase enzymes. Conclusions: This review article has presented 6 detailed comparisons of plants that have a hypoglycemic activity that can be used in the treatment of diabetes mellitus in Indonesia and we believe can be useful for students, researchers, or practitioners. Keywords: Diabetes mellitus, hypoglycemia, Indonesian plants

Author(s):  
Deepa Rajendiran ◽  
Subbulakshmi Packirisamy ◽  
Krishnamoorthy Gunasekaran

 Diabetes mellitus is a chronic metabolic disease. Oxidative stress plays a major part in the pathogenesis of diabetes. Supplementation with antioxidants and the medicinal plants which possess antioxidants activity have been reported their hypoglycemic activity. The antioxidants are used to treat and reduce the complication of diabetes mellitus. The diet supplementations of antioxidants vitamins are beneficial in the treatment of diabetes. This review article was summarizing the role of antioxidants in diabetes mellitus.


Author(s):  
Akshay S Jadhav ◽  
Pallavi S Kale ◽  
Vaishnavi N Pankade ◽  
Snehal A Kardule ◽  
Shubhangi B Hase ◽  
...  

Now days lot of diabetic medicine are available in market having chemical substance. They have lots of side effect but now days lot of anti diabetic medicines are available but sometimes they does not show effect on same patient. Their bodies does not stimulate B-pancreatic cells in bodies which are insulin production. To overcome this problems by using anti diabetic herbal formulation. It is effective, safe to use It maintain blood sugar level , Regulate the blood flow, It has anti diabetic , antioxidant , anticancer, anti microbial and antiinflammatory properties without any side effect.


Author(s):  
Chresni F. Wijaya

Objective: To find out whether diabetes mellitus and/or hypertension is associated with endometrial cancer and could increase the staging of the cancer. Method: This was an analytic retrospective descriptive study with cross sectional design. Data were taken from the medical record of patients diagnosed as having endometrial cancer in Obstetrics and Gynecology Department of Dr. Hasan Sadikin Hospital from 1st January 2007 - 31st December 2011 and analyzed descriptively. Result: There were 125 cases of endometrial cancer. Prevalence was 2.56 %. The incidence increased in age > 40 y/o (92 %) and had diabetes mellitus and/or hypertension (66.4 %). Conclusion: Diabetes mellitus and/or hypertension were associated with risk factors of endometrial cancer but not proven to increase the staging of the cancer. [Indones J Obstet Gynecol 2012; 36-3: 140-3] Keywords: diabetes mellitus, endometrial cancer, hypertension


Author(s):  
Vaishnavi Joshi ◽  
Rajendra Huparikar

Diabetes Mellitus refers to a group of common metabolic disorders that share the phenotype of hyperglycemias. Depending upon factors contributing to hyperglycemia include reduced insulin secretion, glucose utilization and increased glucose production. Diabetes mellitus is now become most common among all diseases in the present era. In India, this is increasing rapidly and seems that India is going to be capital of Diabetes Mellitus in next coming years. According to Ayurvedic texts, Acharya Charaka has explained about Prameha which can be com- pared with Diabetes Mellitus. The main symptom of Prameha is ‘Prabhuta Aavila Mutrata. Tridosha dushti in Prameha progressively leads to affect Rasa, Meda, Shukra, Ambu, Lasika, Majja and Oja. All these affected Dosha and Dushya influence Basti and manifest the symptom like ‘Prabhuta Avila Mutrata’. Virechana was giv- en in this case because Acharya Charak has mentioned dushti of Kapha, Pitta and Vata is present in Prameha. Phalashruti of Virechana says that there is elimination of Dosha in the sequence of Vit (mala), Pitta, Kapha, Anil. Hence role of Virechana is important in the Chikitsa of Prameha. Keywords: Diabetes Mellitus, Prameha, Samshodhan, Virechan.


2020 ◽  
Vol 1 (2) ◽  
pp. 28-31
Author(s):  
Rachmat Hidayat ◽  
Lusia Hayati ◽  
Nita Parisa

Diabetes Mellitus (DM) is a degenerative disease that continues to increase in numberin Indonesia and is a disease that is spread throughout the world due to unbalancednutritional conditions. Treatment of diabetes mellitus is a chronic and lifelongtreatment. Treatment of diabetes mellitus, such as the use of insulin and oralantihyperglycemia drugs, is relatively expensive, is used for a long time and can causeunwanted side effects. There are many plants that have potential as antihyperglycemiadrugs. One of the active compounds that act as antihyperglycemia isflavonoids.Flavonoids derived from various types of plants studied are thought to actas antihyperglycemic agents. Flavonoids are known to have the ability to scavenge freeradicals or act as natural antioxidants. The antioxidant activity of flavonoids is relatedto phenolic –OH groups which can capture or neutralize free radicals (such as ROS orRNS). Flavonoids can play a role in pancreatic tissue damage caused by DNA alkylationdue to alloxan induction as a result of improving the morphology of the rat pancreas(Prameswari and Widjanarko, 2014).


2017 ◽  
Vol 5 (1) ◽  
pp. 37
Author(s):  
Meta Adiwinata Atmaja ◽  
Noor Diani ◽  
Devi Rahmayanti

ABSTRAKDiabetes mellitus merupakan penyakit yang tidak bisa disembuhkan tapi bisa di dikendalikan dengan penggunaan insulin namun, dalam memberikan pengobatan injeksi insulin yang benar adalah benar dosis, benar cara, benar waktu dan benar lokasi. Penelitian ini bertujuan untuk menilai penggunaan injeksi insulin pen pada penderita diabetes mellitus di RSUD Ulin Banjarmasin. Penelitian ini menggunakan metode deskriptif untuk mendeskripsikan peristiwa-peristiwa penting yang terjadi. Responden berjumlah 30 orang. Teknik pengambilan sampel menggunakan accedental sampling. Waktu penelitian bulan Desember 2016-Januari 2017. Instrumen yang digunakan berupa kuesioner demografi dan format penilaian untuk mengevaluasi cara penggunaan injeksi insulin pen. Hasil penelitian menunjukan data 20 (66,7%) responden sudah tepat dan benar dalam menggunakan injeksi insulin pen dan 10 (33,3%) responden yang belum tepat dan benar dalam menggunakan injeksi insulin pen. Perlu dilakukan program untuk mengevaluasi tentang cara penggunaan injeksi  insuin  pen  sehingga  mampu  mengoptimalkan  penerapan  penggunaan injeksi insulin pen yang baik dan tepat.Kata-kata kunci: diabetes mellitus, evaluasi insulin, insulin.ABSTRACTDiabetes mellitus is one of a disease that can not be cured but can be control with insulin treatment. However, in providing treatment of insulin injections also with right dose, right lane, right time and right location. This study aims to Assessed the use of insulin pen injection on diabetes mellitus patients in hospital Ulin Banjarmasin. This study was used a descriptive method to described the important events that occurred. Respondents were 30 people. The sampling technique used accidental sampling. Study scheduled in December 2016-January 2017. The instruments used were a questionnaire on demographic and format of assessment to evaluate how to use insulin pen injection. The results showed the data of 20 (66.7%) of respondents were corrected and in the proper used of insulin injection pen and 10 (33.3%) of respondents were not precised and corrected in using insulin pen injection. It should be carried out to evaluate the program on how to use Insulin pen injection so as to optimised the use of the application insulin injection pen that is good and right. Keywords : diabetes mellitus, evaluation of insulin, insulin.


2020 ◽  
Vol 1 (2) ◽  
pp. 32-35
Author(s):  
Mustofa

Diabetes mellitus is a metabolic disease characterized by an increase in blood sugardue to defects in insulin secretion, insulin sensitivity, or both. The number ofpeople with diabetes mellitus in Indonesia has increased every year. The numberof people with diabetes is 6.9% in 2013 to 10.9% in 2018. Various therapies have beencarried out for the treatment of Diabetes Mellitus, one of which is herbal therapy.Gynura Procumbens is a plant that is widely used as a treatment for diabetes mellitus,kidney, rash and fever, and hypertension. The flavonoid content in GynuraProcumben replaces the decrease in blood sugar. This review article attempts toexplain the role of Gynura Procumbens as an antidiabetic therapy in previous studies.The method used in this article is through searching articles through the NCBIdatabase and Google Scholar. The results of an article search found that GynuraProcumben has antidiabetic potential which can reduce blood sugar in patients withDiabetes Mellitus


Diabetes mellitus (DM) affects a high proportion of the Brazilian population. Various organs are affected, including oral tissues. Thus, the objective of this article is to review the relationship between DM and oral health, highlighting the importance of the dentist's performance in affected patients. The method used was a literature review using the following databases: LILACS, BBO, SCIELO and Google Scholar, using the keywords: diabetes mellitus, diabetes mellitus and dentistry, dentist and diabetic patients. The method used was a literature review using the following databases: LILACS, BBO, SCIELO and Google Scholar, using the keywords: diabetes mellitus, diabetes mellitus and dentistry, dentist and diabetic patients. As a result, it showed the consensus among studies on the finding that patients with DM have oral problems, gingival and periodontal disease, abnormalities in the composition of saliva, among others. Regarding caries in diabetics, there is no unanimity, some studies confirm the increase in caries in this group, in others this relationship is not significant. The study shows that dental control is paramount in the treatment and prevention of DM. Oral health education can minimize the risks caused by this pathology. The well-prepared dentist can contribute to the prevention and early diagnosis of diabetes complications, an essential factor for a good treatment of the disease and a better quality of life for these individuals.


2017 ◽  
Vol 4 (3) ◽  
pp. 66
Author(s):  
Milena Borges De Castro ◽  
Vitoria Aguiar De Faria ◽  
Edilberto Vanconcelos Pereira Júnior ◽  
Izabela Aguiar De Faria ◽  
Iago Assunção Pereira ◽  
...  

Introdução: A retinopatia diabética é uma severa complicação recorrente do diabetes 1 e 2, afastá-la exige um acompanhamento médico enérgico e uma atenção principalmente para o controle de seus fatores de risco. Objetivo: Identificar fatores de risco para retinopatia diabética a partir de publicações recentes em base de dados diversas.  Metodologia: Pesquisa retrospectiva, não-sistemática das bases de dados Lilacs, SciELO e Pubmed empregando os termos “retinopatia diabética”, “diabetes mellitus”, “fatores de risco”, “nefropatia diabética”, “glaucoma”, “catarata”, “miopia”, “controle glicêmico”, “hipertensão”, “dislipidemia”, “obesidade”, “gestação” e seus equivalentes em língua inglesa. Resultados: Os principais fatores de risco elegidos foram divididos em seções didáticas e explanados para melhor elucidação do tema. Conclusão: Fatores de risco para retinopatia diabética há algumas décadas são discutidos e avaliados em diversas pesquisas por diferentes regiões e mostram resultados confluentes em todo mundo.   Palavras-chave: Diabetes Mellitus, Retinopatia diabética, Fatores de risco. ABSTRACT Introduction: Diabetic retinopathy is a severe recurrent complication of diabetes 1 and 2, moving it away requires vigorous medical monitoring and attention primarily to control of its risk factors. Objective: To identify risk factors for diabetic retinopathy from recent publications in a variety of databases. Methods: Non-systematic search of Lilacs, SciELO and Pubmed databases using the terms "diabetic retinopathy", "diabetes mellitus", "risk factors", "diabetic nephropathy", "glaucoma", "cataract", "myopia", "Glycemic control", "hypertension", "dyslipidemia", "obesity", "gestation" And their equivalents in English. Results: The main risk factors chosen were divided into didactic sections and explanations to better elucidate the theme. Conclusion: Risk factors for diabetic retinopathy for some decades are discussed and evaluated in several researches by different regions and show confluent results worldwide. Keywords: Diabetes Mellitus, Diabetic retinopathy, Risk factors.


Sign in / Sign up

Export Citation Format

Share Document