scholarly journals Child-resistant features of pharmaceutical packaging in the egyptian and global market; a comparative study

2020 ◽  
Author(s):  
Mai Ahmed S. Hussein ◽  
◽  
Mohamed Attia ◽  
Noha Mohamed ◽  
◽  
...  
Keyword(s):  
Young Child ◽  
Comparative Study ◽  
Chronic Diseases ◽  
Child Behavior ◽  
Pharmaceutical Products ◽  
Global Market ◽  
Potential User ◽  
Children Under Five ◽  
Under Five ◽  
Children Under 5

Child-Resistant packaging is substantial requirement especially when it is related to pharmaceuticals. Children under five years old are the most groups in risk of drug poisoning, as a result of their constant passion and attracting their attention to medicines, especially the distinctive color and small size. Due to the presence of medicines for adults, especially chronic diseases that require the presence of the drug always at home with exciting properties for the passion of a young child who is affected by colors and the small size which they can insert easily into their mouths. The child-resistant features attached to packages may present a problem (e.g., how to open the package) to its potential user (child or adult). Many of these features are used with the primary packaging and less for the secondary ones. Are these features efficient with available cost or not. Evaluation of each one might be varied according to package structure, level and child behavior. Therefore, the importance of adding some features in the pharmaceutical packaging Child-Resistant, in order to achieve the safety of children with a targeted age (children under 5 years old). By adding these special properties to the pharmaceutical packaging it will affect the design of the pharmaceutical packaging. Finally, this paper aimed to review and evaluate the child resistant features & securing methods that are used with pharmaceutical products in the Egyptian market, with which are available globally, then make a comparison between them by description and analysis.

scholarly journals Correlation between Nutritional Status and Pneumonia among 6-59 Months Years Old in Tangerang, Banten

2020 ◽  
Author(s):  
Zico Permadi ◽  
◽  
Maria Ekawati ◽  
Citra Ayu Aprilia ◽  
◽  
...  
Keyword(s):  
Nutritional Status ◽  
Community Health Center ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Children Under Five ◽  
Under Five ◽  
Independent Variable ◽  
Weight For Age ◽  
Children Under 5

ABSTRACT Background: Pneumonia is still causing the most deaths among children in developing countries. This disesase often occurs in children under 5 years of age. Nutritional status is a factor that is closely related to infectious diseases such as pneumonia. This study aimed to examine the correlation between nutritional status and pneumonia among 6-59 months years old in Tangerang, Banten. Subject and Methods: A cross-sectional study was conducted at Pakuhaji Community Health Center, Tangerang, Banten, from January to February 2018. A total of 29 children under five were enrolled in this study. The dependent variable was pneumonia. The independent variable was nutritional status. The data were collected from direct measurement of the children under five and questtioner. The data were analyzed by Chi-square. Results: As many as 16 children under five (55.17%) had pneumonia, 7 children under five (24.13%) were malnutrition, 3 children under five (10.34%) were short, and 5 children under five (7.24%) were thin. Nutritional status based on weight for age and weight for height had differences in nutritional status with the incidence of pneumonia among children under five, and they were statistically significant (p< 0.001). Conclusion: Nutritional status is associate with the incidence of pneumonia among 6-59 months years old (children under five) in Tangerang, Banten. Keywords: pneumonia incidence rate, pneumonia, nutritional status, chidren under five Correspondence: Citra Ayu Aprilia. Faculty of Medicine, Universitas Pembangunan Nasional Veteran Jakarta. Email: [email protected]. Mobile: +628122090545. DOI: https://doi.org/10.26911/the7thicph.03.13

scholarly journals Comorbidities and Factors Associated with Mortality among Children under Five Years Admitted with Severe Acute Malnutrition in the Nutritional Unit of Jinja Regional Referral Hospital, Eastern Uganda

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Desire Banga ◽  
Melvis Baren ◽  
Namale Vivian Ssonko ◽  
Franck Katembo Sikakulya ◽  
Yves Tibamwenda ◽  
...  
Keyword(s):  
Severe Acute Malnutrition ◽  
Referral Hospital ◽  
Acute Malnutrition ◽  
Health Concern ◽  
Regional Referral Hospital ◽  
Children Under Five ◽  
Under Five ◽  
Factors Associated ◽  
Eastern Uganda ◽  
Children Under 5

Background. Mortality among children with severe acute malnutrition remains an immense health concern in the hospitals in developing countries, but its attributes are not completely assessed in various hospital settings. The aim of this study was to determine the proportion of mortality, the comorbidities, and factors associated with in-hospital mortality among children under five years of age admitted with severe acute malnutrition at Jinja Regional Referral Hospital, Eastern Uganda. Methods. This was a hospital-based analytical and descriptive prospective cohort study conducted in the nutritional unit of Jinja Regional Referral Hospital. A total of 338 children and their caretakers who met the criteria were consecutively enrolled into the study. Descriptive statistics were used to each of the independent factors, and comorbidities were subjected to chi-squared test followed by logistic regression analysis to assess its association incidence of mortality among children. All independent variables with p values ≤ 0.05 were entered into a multivariate model for factors and comorbidities independently. Factors and comorbidities with p values ≤ 0.05 were considered as associates of mortality among children. Results. Of the 338 children under 5 years of age enrolled, 49 (14.5%) died, although the majority of children were diagnosed with dehydration, 128 (37.9%); pneumonia, 127(37.6%); and malaria, 87(25.7%). Anemia ( aRR = 2.9 , 95% CI: 1.23-6.62, p = 0.01 ), bacteremia ( aRR = 10.0 , 95% CI: 3.62-29.01, p = 0.01 ), HIV ( aRR = 4.8 , 95% CI: 1.42-16.30, p < 0.01 ), TB ( aRR = 4.3 , 95% CI: 1.28-14.49, p < 0.02 ), and shock ( aRR = 60.9 , 95% CI: 9.05-410.28, p < 0.01 ) were the comorbidities significantly associated with a likelihood of mortality. Conclusions. The mortality among children under 5 years of age admitted with severe acute malnutrition is still high (14.5% versus 5%). The comorbidities are significantly associated with mortality. The clinicians are recommended to follow-up closely patients with severe acute malnutrition and to focus on the critical comorbidities identified.

scholarly journals Asymptomatic Intestinal Parasitic Infestations among Children Under Five Years in Selected Communities in the Ho Municipality, Ghana

2020 ◽  
Vol 30 (6) ◽  
Author(s):  
G.E. Kpene ◽  
S.Y. Lokpo ◽  
J.G. Deku ◽  
E. Agboli ◽  
P.K. Owiafe
Keyword(s):  
Risk Factors ◽  
Rural Communities ◽  
Intestinal Parasites ◽  
P Value ◽  
Binary Logistic Regression Analysis ◽  
Children Under Five ◽  
Under Five ◽  
Factors Associated ◽  
Asymptomatic Children ◽  
Children Under 5

BACKGROUND፡ The study investigated intestinal parasitic infestations (IPIs) and possible risk factors associated with asymptomatic children under five (5) years in five (5) selected communities in the Ho Municipality.METHODS: The study design was cross- sectional, with a simple random sampling technique involving 150 asymptomatic children under 5 years from 5 selected communities (Klave, Hoe, Freetown, Dave and Godokpe) in the Ho Municipality. A questionnaire was used to obtain socio-demographics and other relevant parameters. Direct wet preparation, formol-ether concentration and Modified ZN staining techniques were used for the identification of intestinal parasites from participants’ stool samples. The Fisher’s exact test and binary logistic regression analysis were used to determine the difference in IPIs proportions and assess the risk factors associated with IPIs respectively.RESULTS: The overall IPIs cases was 14% (21/150). Cryptosporidium spp was most predominant [5.3% (8/150)], followed by Entamoeba spp [3.3% (5/150)], Cyclospora cayetenensis [2.7% (4/150)], Ascaris lumbricoides [1.3% (2/150)], Giardia lamblia [0.7% (1/150)] and Strongyloides stercoralis [0.7% (1/150)]. Children in rural communities (23.4%) recorded significantly higher case rate compared to those in urban communities (9.8%0), (p=0.04). Lower educational attainment of mother [OR=0.55, 95% CI (0.37 – 0.83), p-value = 0.015] andresidence in rural communities [OR = 0.53, 95% CI (0.33 –0.88)], p-value = 0.025] were significantly associated with IPIs.CONCLUSION: Asymptomatic IPIs are quite prevalent among children under 5 years in the Ho Municipality. The study thus recommends active sensitization programs for parents/guardians on preventive measures and school health programs should be instituted in rural communities.

scholarly journals Enrichment of Biscuits with Andaliman and Fermented Buffalo Milk Biscuits for the Intervention of Malnutrition in Children Under Five

2021 ◽  
Vol 9 (E) ◽  
pp. 670-674
Author(s):  
Diana Sembiring ◽  
Evawany Y. Aritonang ◽  
Amir Purba ◽  
Rahayu Lubis
Keyword(s):  
Buffalo Milk ◽  
Effective Intervention ◽  
Expert Teachers ◽  
Nutritional Content ◽  
Ministry Of Health ◽  
Children Under Five ◽  
Under Five ◽  
Children Under 5

BACKGROUND: Nutritional problems in children under 5 in Indonesia are very large and need effective intervention. Local ingredient is potential to create enrichment biscuits. AIM: This study aims to produce biscuits enriched with Andaliman (Zanthoxylum acanthopodium) and fermented buffalo milk and to perform organoleptic tests on the taste, color, aroma, and texture of the biscuits. METHODS: Three types of biscuits were made, namely, biscuits without Andaliman and fermented buffalo milk, biscuits with 2 g of Andaliman and 200 g of fermented buffalo milk, and biscuits with 3 g of Andaliman and 200 g of fermented buffalo milk. The all three biscuits were then tested organoleptically in the form of preferences by a panel of expert teachers to see choices for taste, color, aroma, and texture. The biscuits are then tested in a laboratory to assess their nutritional content. RESULTS: Biscuits with 2 g of Andaliman and 200 g of fermented buffalo milk had the greatest preference. Statistically, the three groups of biscuits differed in taste, aroma, and texture (p < 0.05). The nutritional content of biscuits is above the standards set by the Ministry of Health. CONCLUSION: Biscuits containing 2 g of Andaliman and 200 g of fermented buffalo milk have the potential to be produced as one of the intervention methods for under 5-year-old children malnutrition in Indonesia.

scholarly journals Prevalence of pneumonia and risk factors of pneumonia mortality among children under five years.

2018 ◽  
Vol 2 (2) ◽  
Author(s):  
Francis Adjei Osei ◽  
Kofi Akohene Mensah ◽  
Daniel Ansong ◽  
Peter Agyei-Baffour ◽  
Sandra Kwarteng Owusu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Mortality Rate ◽  
Associated Factors ◽  
Maternal Education ◽  
Sub Saharan Africa ◽  
Primary Data ◽  
Categorical Variables ◽  
Children Under Five ◽  
Under Five ◽  
Children Under 5

BackgroundPneumonia remains the foremost cause of death in children under 5 years of age especially in sub-Saharan Africa killing nearly 1 million annually.Aim Identify pneumonia prevalence, mortality rate and associated factors among children under five admitted to Komfo Anokye Teaching Hospital (KATH) in Ghana.MethodsUsing a prospective cross-sectional study method, a consecutive sample of 157 children under 5 admitted to the KATH for pneumonia from June to August 2016 was selected. A structured questionnaire was used to collect primary data from their caregivers and secondary data from the patient record using a structured data extraction form. Continuous and categorical variables were described and chi-square test employed to determine the associated factors of pneumonia mortality. Multivariate logistics regression model was used to test for the strength of the association to unearth the risk factors of pneumonia mortality.Results The study found a prevalence of pneumonia of 18.40% with a mortality rate of 12.74%. Pneumonia mortality was found to be associated with maternal education (p<0.001), occupation (p=0.01), income (p=0.02), pneumonia severity (p<0.001) and number of rooms occupied by a household (p=0.01). In multivariate regression, severe pneumonia increased the odds of pneumonia mortality (OR=18.23, 95% CI= 4.37-76.10, p<0.001). However, maternal education showed reduced likelihood of pneumonia mortality (OR=0.59, 95% CI= 0.36-0.97, p=0.039). ConclusionPneumonia places a high burden on the health of children under five years admitted to KATH. Health workers need to sensitize caregivers on the signs and symptoms of pneumonia to aid early detection and reporting which could reduce mortality.

scholarly journals PO 8444 CHARACTERISATION OF PATHOGENS CAUSING DIARRHOEA IN CHILDREN UNDER FIVE IN LAMBARÉNÉ, GABON

2019 ◽  
Vol 4 (Suppl 3) ◽  
pp. A38.1-A38
Author(s):  
Gédéon P Manouana ◽  
Gedeon Bingoulou Matsougou ◽  
Natalie Byrne ◽  
Philipp Hofmann ◽  
mirabeau Mbong Ngwese ◽  
...  
Keyword(s):  
Giardia Lamblia ◽  
Study Participant ◽  
Control Measures ◽  
Effective Control ◽  
Cross Sectional ◽  
National Immunisation Programme ◽  
Children Under Five ◽  
Cyclospora Cayetanensis ◽  
Under Five ◽  
Children Under 5

BackgroundDiarrhoeal disease remains the second leading cause of death in children under five years, being associated with about 525,000 deaths every year. The most common pathogens worldwide are Shigella spp/EIEC, rotavirus, adenovirus 40/41, ST-ETEC and Cryptosporidium spp. Public health interventions rely on estimates of pathogen-specific burden for prioritisation. Sadly, comprehensive data on the aetiology of diarrhoea in children is lacking for Gabon. This study aimed to identify the spectrum of pathogens found in Lambaréné, Gabon and provide baseline data on their prevalence, needed for implementation of effective control measures.MethodsA cross-sectional study was conducted at Albert Schweitzer and Georges Rawiri Regional hospitals in Lambaréné from February 2017 to February 2018. A consecutive sample of children under 5 year old with diarrhoea or a history of diarrhoea within the previous three days were prospectively studied. A single stool sample was collected from each study participant and processed using commercial rapid immunoassays to detect antigens of rotavirus, adenovirus, and Cryptosporidium spp. Multiplex PCR was used for Cryptosporidium spp., Giardia lamblia and Cyclospora cayetanensis detection, and characterisation of E. coli strains.ResultsOut of 188 participants who provided stool samples, one or more pathogens could be detected in 34.6% of the cases. The most prevalent parasites were Giardia lamblia (14.9%), Cryptosporidium spp. (11.7%), and Cyclospora cayetanensis (2.7%). Enteric viruses also were identified in these children: 10.6% and 1.6% of rotavirus and adenovirus, respectively. Multiple pathogens were detected in 5.3% of samples.ConclusionThis analysis of the causes of diarrhoea in children under 5 years of age in our setting showed three main pathogens: Giardia lamblia, Cryptosporidium spp. and rotavirus. Our study confirms major agents of acute diarrhoeal diseases in children, highlights research needs (Cryptosporidium) and supports the introduction of new tools such as the implementation of the rotavirus vaccine in the national immunisation programme.

scholarly journals Studi Kasus Ibu Melakukan Kunjungan Ulang Pada Balita Pneumonia Di Wilayah Kerja Puskesmas Landasan Ulin Kalimantan Selatan

2019 ◽  
Vol 9 (3) ◽  
pp. 145
Author(s):  
Eka Handayani ◽  
Septi Anggraeni
Keyword(s):  
One Health ◽  
Respiratory Infections ◽  
Developed Countries ◽  
Acute Respiratory Infections ◽  
Children Under Five ◽  
Under Five ◽  
The World ◽  
Repeat Visits ◽  
Repeated Visit ◽  
Children Under 5

Acute respiratory infections affect many children, both in developing countries and in developed countries. acute respiratory infections that affect death and often affect children under 5 years of age, namely pneumonia. Pneumonia is the main killer of toddlers in the world with a higher prevalence compared to AIDS, malaria and measles. Every year, it is estimated that more than 2 million children under five die from Pneumonia (1 toddler / 20 seconds) from 9 million total deaths of children under five in the world. In Indonesia, pneumonia is still a big problem considering the mortality rate from this disease is still high.. Knowing the mother's case studies do repeat visits in infants pneumonia in health center Landasan Ulin. A qualitative study through interviews and documentation to one health worker. Not all mothers bring their babies repeated visit only 30% of mothers who commit repeated visit of all children under five suffering from pneumonia. Mother toddler who do repeat visits by 35% means that more mothers who do not do repeat visits by 65% this is because there are several reasons mothers do not bring toddlers pneumonia to re-visit them her son had recovered and did not cough again, there also reasoned mothers are busy.  

scholarly journals The prevalence and socio-demographic risk factors of coexistence of stunting, wasting and underweight among children under five years in Bangladesh

2021 ◽  
Author(s):  
Mohammad Rocky Khan Chowdhury ◽  
Md Shafiur Rahman ◽  
Baki Billah ◽  
Russell Kabir ◽  
Nirmala K. P. Perera ◽  
...  
Keyword(s):  
Risk Factors ◽  
Negative Binomial ◽  
Negative Binomial Regression ◽  
Educational Status ◽  
Chi Square ◽  
Children Under Five ◽  
Household Level ◽  
Under Five ◽  
Childhood Malnutrition ◽  
Children Under 5

Abstract Background Childhood malnutrition in all its forms is a significant public health challenge for developing countries like Bangladesh. There is a gap in knowledge of the coexistence of various forms of malnutrition among children under five years (under-5) in Bangladesh. This study aims (i) describe prevalence and risk factors for the coexistence of stunting, wasting and underweight among children under-5 in Bangladesh. Methods This study included 6,610 and 7,357 under-5 children from Bangladesh Demographic Health Surveys (BDHS) 2014 and 2017/18 respectively. Associations between coexistence stunting, wasting and underweight and socio-demographic factors were assessed by the Chi-square test and negative binomial regression. Results The prevalence of coexistence of stunting, wasting and underweight gradually declined from 5.2% in 2014 to 2.7% in 2017/18. Children of uneducated mothers ((Adjused incidence rate ratio (aIRR) 5.0, 95% CI 2.3, 11.0)); with low birth weights (aIRR 2.7, 95% CI 1.4, 5.1); children of age group 36–47 months (aIRR 2.5, 95% CI 1.5, 4.1); and children of underweight mothers (aIRR 1.9, 95% CI 1.4, 2.7) were the most important risk factors. However, maternal educational status was not associated with coexistence of stunting, wasting and underweight among children under-5 in 2014 whereas in 2017/18 it was the most influential risk factor. Moreover, watching television less than once a week increased the risk of coexistence of stunting, wasting and underweight by 54% (aIRR 1.54, 95% CI 1.0, 2.4). Conclusions one out of thirty-five under-5 children were identified to have coexistence of stunting, wasting and underweight in Bangladesh. The burden of malnutrition was disproportionate among uneducated mother, underweight mother, low birth weight and socio-economically poorest household. Our study indicates that there is a need for multi-level interventions from household level to societal level to reduce consequences of childhood malnutrition.

scholarly journals Holistic-comprehensive approaches to improve nutritional status of children under five years

2021 ◽  
Vol 10 (2) ◽  
Author(s):  
Febri Endra Budi Setyawan ◽  
Retno Lestari
Keyword(s):  
Socioeconomic Status ◽  
Environmental Factors ◽  
Nutritional Status ◽  
Correlation Coefficients ◽  
Partial Least Square ◽  
Equation Modeling ◽  
Children Under Five ◽  
Under Five ◽  
Nutritional Status Of Children ◽  
Children Under 5

Background: Malnutrition has been identified as the leading cause of illness and death in almost half of children under 5 years. Hence, to prevent the impact of malnutrition on physical and psychological development, family physicians need to explore new approaches in the health care delivery models that go beyond the scope of practice. A holistic-comprehensive approach will help the physicians develop a more thorough assessment of nutritional status. This study aims to determine factors associated with the nutritional status of children under five years using holistic-comprehensive approaches.Design and Methods: A case–control design was implemented, with emphasis on the identification of cases and control groups; 48 children confirmed malnutrition cases and 48 control without malnutrition were recruited from a Community Integrated Health Center in East Java, Indonesia. The characteristics of agent, host and environment between groups were compared and analyzed using correlation coefficients, odds ratio, logistic regression analysis, and Structural Equation Modeling-Partial Least Square (SEM-PLS).Results: The SEM-PLS results showed that environmental factors have a greater influence on nutritional status (t-value >1.96), compared to the host factors. Furthermore, environmental factors having significant associations with nutritional status were poor socioeconomic status, low maternal educational level and not having exclusive breastfeeding. Also, the results of correlation coefficients and OR showed that birth weight (p=0.000, OR=33) and socioeconomic status (p=0.000, OR=22.3) had strong correlations with nutritional status. Conclusion: Holistic-comprehensive approaches can be used as new ways to determine factors that may be associated with nutritional status of children under 5 years of age.

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