scholarly journals Cancer incidence and mortality in the Bucaramanga metropolitan area, 2003-2007

2012 ◽  
pp. 290-297 ◽  
Author(s):  
Claudia Janeth Uribe ◽  
Sonia Osma ◽  
Victor Herrera

Introduction: Cancer is an important cause of morbidity and mortality worldwide. Population-based cancer registries (PB­CRs) make possible to estimate the burden of this condition. Objetive: To estimate cancer incidence and mortality rates in the Bucaramanga Metropolitan Area (BMA) during 2003-2007. Methods: Incident cases of invasive cancer diagnosed during 2003-2007 were identified from the Bucaramanga Metropolitan Area PBCR (BMA-PBCR). Population counts and mortality were obtained from the Colombian National Administrative De­partment of Statistics (NADS). We estimated total and cancer-specific crude incidence and mortality rates by age group and sex, as well as age-standardized (Segi’s world population) incidence (ASIR[W]) and mortality (ASMR[W]) rates. Statistical analyses were conducted using CanReg4 and Stata/IC 10.1. Results: We identified 8,225 new cases of cancer excluding non-melanoma skin cancer (54.3% among women). Of all cases, 6,943 (84.4%) were verified by microscopy and 669 (8.1%) were detected only by death certificate. ASIR(W) for all invasive cancers was 162.8 per 100,000 women and 177.6 per 100,000 men. Breast, cervix, colorectal, stomach and thyroid were the most common types of cancer in women. In men, the corresponding malignancies were prostate, stomach, colorectal, lung and lymphoma. ASMR(W) was 84.5 per 100,000 person-years in women and 106.2 per 100,000 person-years in men. Breast and stomach cancer ranked first as causes of death in those groups, respectively. Conclusion: Overall, mortality rates in our region are higher than national estimates possibly due to limited effectiveness of secondary prevention strategies. Our work emphasizes the importance of maintaining high-quality, nationwide PBCRs.

Author(s):  
Stephanie C Melkonian ◽  
Hannah K Weir ◽  
Melissa A Jim ◽  
Bailey Preikschat ◽  
Donald Haverkamp ◽  
...  

Abstract Cancer incidence varies among American Indian and Alaska Native (AI/AN) populations, as well as between AI/AN and White populations. This study examined trends for cancers with elevated incidence among AI/AN compared with non-Hispanic White populations and estimated potentially avoidable incident cases among AI/AN populations. Incident cases diagnosed during 2012–2016 were identified from population-based cancer registries and linked with the Indian Health Service patient registration databases to improve racial classification of AI/AN populations. Age-adjusted rates (per 100,000) and trends were calculated for cancers with elevated incidence among AI/AN compared with non-Hispanic White populations (rate ratio >1.0), by region. Trends were estimated using joinpoint regression analyses. Expected cancers were estimated by applying age-specific cancer incidence rates among non-Hispanic White populations to population estimates for AI/AN populations. Excess cancer cases among AI/AN populations were defined as observed minus expected cases. Liver, stomach, kidney, lung, colorectal and female breast cancers had higher incidence rate among AI/AN populations across most regions. Between 2012 and 2016, nearly 5,200 excess cancers were diagnosed among AI/AN populations, with the largest number of excess cancers (1,925) occurring in the Southern Plains region. Culturally informed efforts may reduce cancer disparities associated with these and other cancers among AI/AN populations.


2019 ◽  
Vol 105 (2) ◽  
pp. 121-137 ◽  
Author(s):  
Carlotta Buzzoni ◽  
Emanuele Crocetti ◽  
Stefano Guzzinati ◽  
Luigino Dal Maso ◽  
Silvia Francisci ◽  
...  

Objective: To evaluate short-term (2003–2014) cancer incidence and mortality trends in Italy. Methods: Italian Cancer Registries data, available in the AIRTUM database, from 17 out of 20 regions were used. The number of incident cases and deaths were estimated for those registries and those years with incomplete information. Age-standardized rates, overall and stratified by geographic area, region, sex, cancer site, and major age group, were computed. Time trends were expressed as annual percent change of rates. Results: In Italy, among males, incidence rates for all cancers showed during 2003–2014, a significant decrease (−0.9%/year), with stronger reductions in the northwest (−1.3%/year) and northeast (−2.0%/year since 2006) than in central (−0.7%/year) and southern (−0.4%/year) areas. Among females, a weak but significant overall reduction was detected (−0.1%/year), with a stronger decrease in the northwest (−0.5%/year). Incidence increased among women in the south (0.3%/year) of Italy. Mortality decreased in both sexes (−1.0%/year among males and −0.5%/year among females), but not in the south, where rates had a stable tendency. Conclusions: Incidence among males decreased, supported by trends for prostate, lung, colorectal, and urinary bladder cancers; among females the. The overall cancer incidence trend was stable, or even decreasing, in the northern and central areas and increasing in the southern areas, due to lung, thyroid, and melanoma rising trends. Study results provided information on the outcomes, in terms of cancer incidence and mortality, of primary and secondary prevention measures employed by regional health systems.


2017 ◽  
Vol 28 (1) ◽  
pp. 20-34 ◽  
Author(s):  
Pavel Chernyavskiy ◽  
Mark P Little ◽  
Philip S Rosenberg

Age–period–cohort models are a popular tool for studying population-level rates; for example, trends in cancer incidence and mortality. Age–period–cohort models decompose observed trends into age effects that correlate with natural history, period effects that reveal factors impacting all ages simultaneously (e.g. innovations in screening), and birth cohort effects that reflect differential risk exposures that vary across birth years. Methodology for the analysis of multiple population strata (e.g. ethnicity, cancer registry) within the age–period–cohort framework has not been thoroughly investigated. Here, we outline a general model for characterizing differences in age–period–cohort model parameters for a potentially large number of strata. Our model incorporates stratum-specific random effects for the intercept, the longitudinal age trend, and the model-based estimate of annual percent change (net drift), thereby enabling a comprehensive analysis of heterogeneity. We also extend the standard model to include quadratic terms for age, period, and cohort, along with the corresponding random effects, which quantify possible stratum-specific departures from global curvature. We illustrate the utility of our model with an application to metastatic prostate cancer incidence (2004–2013) in non-Hispanic white and black men, using 17 population-based cancer registries in the Surveillance, Epidemiology, and End Results Program.


2012 ◽  
pp. 256-266 ◽  
Author(s):  
Maria Clara Yepez ◽  
Luis Eduardo Bravo ◽  
Arsenio Hidalgo Troya ◽  
Daniel Marcelo Jurado ◽  
Luisa Mercedes Bravo

Introduction: In Colombia, information on cancer morbidity at the population level is limited. Incidence es­timates for most regions are based on mortality data. To improve the validity of these estimates, it is necessary that other population-based cancer registries, as well as Cali, provide cancer risk information. Objective: To describe the incidence and cancer mortality in the municipality of Pasto within the 1998-2007 period. Methodology: The study population belongs to rural and urban areas of the municipality of Pasto. Collection, processing, and systematization of the data were performed according to internationally standardized parame­ters for population-based cancer registries. The cancer incidence and mortality rates were calculated by gender, age, and tumor site. Results: During the 1998-2007 period 4,986 new cases of cancer were recorded of which 57.7% were in female. 2,503 deaths were presented, 52% in female. Neoplasm-associated infections are the leading cause of cancer morbidity in Pasto: stomach cancer in males and cervical cancer in females. Discussion: Cancer in general is a major health problem for the population of the municipality of Pasto. The overall behavior of the increasing incidence and cancer mortality in relation to other causes of death show the need to implement and strengthen prevention and promotion programs, focusing especially on tumors that produce greater morbidity and mortality in the population.


BMJ Open ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. e050387
Author(s):  
Jing-Yuan Wang ◽  
Qiang-Wei Zhang ◽  
Kaixue Wen ◽  
Chen Wang ◽  
Xiaolin Ji ◽  
...  

ObjectivesLaryngeal cancer is the most prevalent entity of head and neck cancer. Knowing the trends of incidence and mortality of laryngeal cancer is important for the reduction in related disease burden.DesignPopulation-based observational study.Main outcomes and measuresThe incidence and mortality data of laryngeal cancer were retrieved from the Global Burden of Disease study 2017 online database. The estimated average percentage change was used to quantify the trends of laryngeal cancer incidence and mortality at the global, regional and national levels.ResultsGlobally, the numbers of incident cases and deaths due to laryngeal cancer increased 58.7% and 33.9%, respectively, from 1990 to 2017. However, the overall age-standardised incidence rate (ASIR) and age-standardised mortality rate decreased by 0.99% (95% CI 0.83% to 1.14%) and 1.62% (95% CI 1.50% to 1.74%) per year, respectively. These decreases were ubiquitous worldwide. However, unfavourable trends in the ASIR of laryngeal cancer were also observed in a total of 51 developing countries.ConclusionsThe incidence and mortality rates of laryngeal cancer have significantly decreased at the global level and in most countries over the past three decades. The regions that showed an increasing incidence trend deserve more attention.


Neurology ◽  
2020 ◽  
pp. 10.1212/WNL.0000000000011219
Author(s):  
Ruth Ann Marrie ◽  
Colleen Maxwell ◽  
Alyson Mahar ◽  
Okechukwu Ekuma ◽  
Chad McClintock ◽  
...  

Objective:To determine whether cancer risk differs in people with and without multiple sclerosis (MS), we compared incidence rates and cancer-specific mortality rates in MS and matched cohorts using population-based data sources.Methods:We conducted a retrospective matched cohort study using population-based administrative data from Manitoba and Ontario, Canada. We applied a validated case definition to identify MS cases, then selected 5 controls without MS matched on birth year, sex and region. We linked these cohorts to cancer registries, and estimated incidence of breast, colorectal and 13 other cancers. For breast and colorectal cancers, we constructed Cox models adjusting for age at the index date, area-level socioeconomic status, region, birth cohort year and comorbidity. We pooled findings across provinces using meta-analysis.Results:We included 53,984 MS cases and 266,920 controls. Multivariable analyses showed no difference in breast cancer risk (pooled hazard ratio [HR] 0.92 [95%CI: 0.78-1.09]) or colorectal cancer risk (pooled HR 0.83 [95%CI: 0.64-1.07]) between the cohorts. Mortality rates for breast and colorectal did not differ between cohorts. Bladder cancer incidence and mortality rates were higher among the MS cohort. Although the incidence of prostate, uterine and central nervous system cancers differed between the MS and matched cohorts, mortality rates did not.Conclusion:The incidence of breast and colorectal cancers does not differ between persons with and without MS; however, the incidence of bladder cancer is increased. Reported differences in the incidence of some cancers in the MS population may reflect ascertainment differences rather than true differences.


Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2820
Author(s):  
Daniel Redondo-Sánchez ◽  
Rafael Marcos-Gragera ◽  
Marià Carulla ◽  
Arantza Lopez de Munain ◽  
Consol Sabater Gregori ◽  
...  

Socioeconomic inequalities in cancer incidence are not well documented in southern Europe. We aim to study the association between socioeconomic status (SES) and colorectal, lung, and breast cancer incidence in Spain. We conducted a multilevel study using data from Spanish population-based cancer registries, including incident cases diagnosed for the period 2010–2013 in nine Spanish provinces. We used Poisson mixed-effects models, including the census tract as a random intercept, to derive cancer incidence rate ratios by SES, adjusted for age and calendar year. Male adults with the lowest SES, compared to those with the highest SES, showed weak evidence of being at increased risk of lung cancer (risk ratio (RR): 1.18, 95% CI: 0.94–1.46) but showed moderate evidence of being at reduced risk of colorectal cancer (RR: 0.84, 95% CI: 0.74–0.97). Female adults with the lowest SES, compared to those with the highest SES, showed strong evidence of lower breast cancer incidence with 24% decreased risk (RR: 0.76, 95% CI: 0.68–0.85). Among females, we did not find evidence of an association between SES and lung or colorectal cancer. The associations found between SES and cancer incidence in Spain are consistent with those obtained in other European countries.


2021 ◽  
Author(s):  
Yingmei Li ◽  
Hongtao Wang ◽  
Zilong Lu ◽  
Jiandong Sun ◽  
Jiyu Zhang ◽  
...  

Abstract Background: Eye cancer is relatively rare. Current prevalence and disease burden of eye cancer are unlcear.The purpose of this study was to understand the epidemiology in the incidence and mortality of eye cancer in Shandong Province, and to provide reference for the prevention and control of eye cancer.Methods: Population-based cancer incidence and death data from cancer registries in 2013-2017 was collected by Shandong Center for Disease Control and Prevention (SDCDC). Extracted data were firstly assessed for data quality and then were aggregated by area (urban/rural), gender, and age group [0, 1-4, 5-9, 10-14, …, 85+]. Crude and age-adjusted incidence and mortality rates were calculated.Results: The reported numbers of eye cancer incident cases and deaths in Shandong cancer registry from 2013 to 2017 were 169 and 43, respectively. The crude incidence rate, age-standardized rate of incidence by Chinese population (ASRIC, 2000) and world population (ASRIW) were 11.12/107, 8.92/107 and 12.44/107, respectively. The crude mortality rate, age-standardized rate of mortality by Chinese population (ASRMC, 2000) and world population (ASRMW) were 2.83/107, 1.89/107 and 2.58/107, respectively. There were no marked differences in the incidence and mortality rates between male and female. The incidence rates were similar between rural and urban areas. The mortality rate in rural areas was higher than that in urban areas. The mortality-to-incidence (M/I) ratio in rural areas (0.30) was considerably higher than that in urban areas (0.18). The highest incidence was observed in children aged 0-4 years old, which was true for both urban and rural areas, and for both genders,Conclusion: Eye cancer is not a common malignant tumor in this population. Prevention and control measures should be tailored according to the epidemiological characteristics and risk factors of eye cancer.


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