scholarly journals Perfil epidemiológico, disfunção orgânica e eletrolítica em potenciais doadores de órgãos e tecidos de um hospital do sul do Brasil / Epidemiological profile, organic and electrolytic dysfunction in potential donors of organs and tissues of a hospital of the south of Brazil

Author(s):  
Kelser De Souza Kock ◽  
Mariana Gabriela Santana ◽  
Silvia Catarine Da Silva ◽  
Samuel Brida Andrade ◽  
Edvan Nunes dos Santos

Objetivo: Analisar o perfil epidemiológico e as disfunções orgânicas e eletrolíticas em potenciais doadores de órgãos. Métodos: Estudo transversal, descritivo. Foram selecionados pacientes com morte encefálica, na Unidade de Terapia Intensiva de um hospital do sul do estado de Santa Catarina, no período de 2014 a 2016. Resultados: Foram avaliados 64 indivíduos, com prevalência do sexo masculino (56,3%), com mediana de 51,5 anos de idade. O Acidente Vascular Cerebral mostrou-se como a principal causa de diagnóstico de morte encefálica, em 42% dos casos. Houve doação em 45% dos pacientes, totalizando 120 órgãos ou tecidos doados, destacando-se o globo ocular, os rins e o fígado. Nos exames laboratoriais os pacientes apresentaram uma mediana de 147,0 mmol/L para o sódio, 4,2 mmol/L para o potássio e 246,0 mg/dL para a glicose. O escore de SOFA apresentou mediana geral 6, com maiores valores nos SOFA cardiovascular e respiratório (p<0,001) em relação aos SOFA renal, hematológico e hepático. Conclusão: O perfil epidemiológico dos potenciais doadores é similar a outros estudos. Quanto às disfunções orgânicas eletrolíticas e metabólicas, foram evidenciados distúrbios de hipernatremia e hiperglicemia. As disfunções orgânicas significativas identificadas pelo SOFA foram nos sistemas cardiovascular e respiratório. Neste sentido, especial atenção deve ser dada a estes sistemas para adequada manutenção do potencial doador.Descritores: Morte encefálica, Obtenção de tecidos e órgãos, Eletrólitos, Escores de disfunção orgânicaABSTRACT:Objective: To analyze the epidemiological profile and the organ and electrolytics dysfunctions in potential organ donors. Methods: Cross-sectional, descriptive study. We selected patients with brain death at the Intensive Care Unit of a hospital in the southern state of Santa Catarina, from 2014 to 2016. Results: We evaluated sixty-six individuals, with a prevalence of males (56.3%), with a median age of 51.5 years. The Cerebral Vascular Accident was the main cause of brain death’s diagnosis (42%). There was donation in 45% of the patients, totaling 120 organs and tissue donated, standing out the eyeball, kidneys and liver. In the laboratory tests the patients had a median of 147.0 mmol / L for sodium, 4.2 mmol / L for potassium and 246.0 mg / dL for glucose. The SOFA score presented general median 6, with higher values in cardiovascular and respiratory SOFA (p <0.001) in relation to renal, hematological and hepatic SOFA. Conclusion: The epidemiological profile of potential donors is similar to other studies. As for the organic and metabolic dysfunctions, disorders of hypernatremia and hyperglycemia were evidenced. The significant organic dysfunctions identified by SOFA were in the cardiovascular and respiratory systems. In this sense, special attention should be given to these systems for adequate maintenance of the potential donor.Keywords: Brain death, Tissue and organ procurement, Electrolytes, Organ dysfunction scores

2021 ◽  
Vol 10 (1) ◽  
pp. 26-28
Author(s):  
Gentle S. Shrestha ◽  
Amit S Bhattarai ◽  
Tseten Yonjen ◽  
Ramesh S Bhandari ◽  
Paleswan J Lakhey ◽  
...  

Background and aims: Organ transplant is often the only viable treatment option for various end stage organ failures. Inadequacy of organ procurement from living as well as cadaveric donors is common, more so in developing countries. The aim of this study was to find out the knowledge and attitude regarding organ transplantation. Methods: A questionnaire-based survey was carried out among 150 respondents, who were the visitors of patients admitted to ICU of three tertiary care centres in Kathmandu. Results: Majority of the respondents were male 105 (70%) and 132 (88%) were aware about organ transplant. Likewise, 111 respondents (84.1%) hold the belief that organ transplant save lives. Ninety-four of the responses (34.8%) believe that media was the source of knowledge and 121 (91.7 %) of the respondents stated that organ transplant should be promoted. Majority of them, 80 of the total respondents (60.6%) believed that organ can be donated by both living and deceased donors and 111 (84.1%) of them believed that organ transplant save lives. While 88 of the respondents (66.7%) have heard about brain death, 60 of them (45.4%) believe that there is an organ transplant act in Nepal. Out of all respondents who are aware about transplantation, 91 of them (68.9%) have opinion that they are willing to donate the organ of their beloved ones should there be a situation of brain death. Conclusions: The study concludes that respondents have adequate knowledge regarding organ transplantation. Respondents have overall positive attitude towards organ donation and transplantation.  


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Marcelo Moreno ◽  
Ricardo Ludwig Schmitt ◽  
Maria Gabriela Lang ◽  
Vanessa Gheno

Cutaneous melanoma (CM) is responsible for 75% of deaths from malignant skin cancer. The incidence of CM in the southern region of Brazil, particularly in the western region of Santa Catarina, is possibly higher than estimated. In this study, the clinical and epidemiological profile of patients with CM treated in the western region of Santa Catarina was examined. A cross-sectional study was performed with patients diagnosed with CM from January 2002 to December 2009, from 78 counties of the western region of the state of Santa Catarina. Data were collected using a protocol adapted from the Brazilian Melanoma Group and 503 patients were evaluated. The incidence and prevalence of CM found in this region are much higher than those found elsewhere in the country. This fact is most likely due to the phenotypic characteristics of the population and the high incidence of UV radiation in this region due to its location in southern Brazil, as is the case in the countries of Oceania.


2018 ◽  
Vol 9 (2) ◽  
Author(s):  
Sandra Taveiros Araujo ◽  
Maria Elisângela Torres de Lima Sanches ◽  
Wanubia Santos Nascimento

Objetivo: analisar o perfil epidemiológico das pacientes internadas em uma Unidade de Terapia Intensiva (UTI) materna. Metodologia: Estudo transversal retrospectivo quantitativo, com 70 pacientes internas em uma UTI materna do Estado de Alagoas, Maternidade Santa Mônica (MESM), no ano 2015. Resultados: Os três principais diagnósticos das internações foram as síndromes hipertensivas, síndromes hemorrágicas e cardiopatia. Média de idade 27 anos, a maioria procedente do interior de Alagoas. 48,5% primigesta, taxa de cesárea 94,7%. Procedimentos cirúrgicos mais frequentes foram laparotomia, intubação orotraqueal, e histerectomia. Duração do internamento de 1-31 dias. Taxa de óbito 5,7%. Conclusão: o perfil epidemiológico das pacientes do estudo diverge, em alguns aspectos, de outras pesquisas, sendo elevada, principalmente, as taxas de cesárea e óbito materno, é contraditório também as principais causas de internamento. Assim, a assistência obstétrica no estado de Alagoas precisa avançar para diminuir os óbitos maternos e reduzir a taxa de cesárea.Descritores: Gravidez de alto risco, Unidade de Terapia Intensiva, Mortalidade Materna.ANALYSIS OF THE EPIDEMIOLOGICAL PROFILE OF HOSPITALIZATIONS IN A MATERNAL INTENSIVE CARE UNITObjective: to analyze the epidemiological profile of patients admitted to a Maternal Intensive Care Unit (ICU). Methodolofy: A retrospective quantitative cross-sectional study with 70 inpatients at a maternal ICU in the State of Alagoas, Santa Mônica Maternity (MESM), in the year 2015. Results: The three main diagnoses of hospitalizations were hypertensive syndromes, hemorrhagic syndromes and cardiopathy. Average age 27 years, most coming from the interior of Alagoas. 48.5% primigravida, caesarean section 94.7%. Most frequent surgical procedures were laparotomy, orotracheal intubation, and hysterectomy. Length of stay from 1-31 days. Death rate 5.7%. Conclusion: The epidemiological profile of the patients in the study diverges, in some aspects, from other studies, mainly due to the rates of maternal caesarean section and death, which is also contradictory to the main causes of hospitalization. Thus, obstetric care in the state of Alagoas needs to move forward to reduce maternal deaths and reduce the rate of cesarean section.Descriptors: High risk pregnancy, Intensive care unit, Maternal MortalityEL ANÁLISIS DEL PERFIL EPIDEMIOLÓGICO DE LAS HOSPITALIZACIONES EN UNA UNIDAD DE CUIDADOS INTENSIVOS MATERNALObjetivo: Analizar el perfil epidemiológico de los pacientes hospitalizados en una madre Unidad de Cuidados Intensivos (UCI). Metodología: Estudio retrospectivo transversal cuantitativo con 70 pacientes en una UCI materna interna del Estado de Alagoas, maternidad Santa Mónica (HSHAV) en el año 2015. Resultados: Los tres diagnósticos principales de admisión eran hipertensos trastornos, hemorragia y de la enfermedad cardíaca síndromes. Media de edad 27 años, la mayoría procedente del interior de Alagoas. 48,5% primigesta, tasa de cesárea 94,7%. Los procedimientos quirúrgicos más frecuentes fueron laparotomía, intubación orotraqueal, e histerectomía. Duración de la internación de 1-31 días. Tasa de defunción 5,7%. Conclusión: El perfil epidemiológico de los pacientes en el estudio difieren en algunos aspectos de otras investigaciones que se elevó las tasas de cesárea y sobre todo la muerte materna, es contradictorio también a las principales causas de hospitalización. Así, la asistencia obstétrica en el estado de Alagoas necesita avanzar para disminuir las muertes maternas y reducir la tasa de cesárea.Descriptores: Embarazo de alto riesgo, Unidad de terapia intensive, La mortalidad materna.


1997 ◽  
Vol 7 (1) ◽  
pp. 14-21 ◽  
Author(s):  
Holly G Franz ◽  
William DeJong ◽  
Susan M Wolfe ◽  
Howard Nathan ◽  
Denise Payne ◽  
...  

To examine how a family's understanding of brain death may affect the decision to donate, an interview study was conducted with the immediate next of kin of 164 medically suitable organ donor candidates. Telephone interviews were conducted with members of both donor and nondonor families 4 to 6 months after the relative's death. Only 61% of the donor and 53% of the nondonor respondents said they had received an explanation of brain death. Few respondents reported that the hospital or organ procurement organization staff used visual aids to clarify or reinforce the information they were given. Next of kin who decided against donation had far less understanding of brain death than did those who decided in favor of it. Before making an organ donation request, healthcare providers must inquire about and address common misunderstandings people have about brain death. Healthcare teams should develop and be trained on a clear protocol for communicating with the families of patients who may be potential organ donors.


2010 ◽  
Vol 8 (1) ◽  
pp. 0-0
Author(s):  
Viktorija Černiauskienė ◽  
Monika Čiplytė ◽  
Saulius Vosylius

Viktorija Černiauskienė, Monika Čiplytė, Saulius VosyliusVilniaus universiteto Anesteziologijos ir reanimatologijos klinika, Vilniaus greitosios pagalbos universitetinė ligoninė,Šiltnamių g. 29, LT-04130 VilniusEl paštas: [email protected] Įvadas / tikslasDonorinių organų poreikis gerokai viršija atliktų organų transplantacijų skaičių. Dažniausios priežastys, dėl kurių potencialūs donorai netampa efektyviais donorais, yra donoro artimųjų prieštaravimas donorystei, medicininės kontraindikacijos, logistikos problemos, neadekvatus potencialių donorų gydymas iki eksplantacijos operacijos. Šio straipsnio tikslas yra apžvelgti naujausius medicinos mokslo laimėjimus atliekant potencialių organų donorų priežiūrą reanimacijos ir intensyviosios terapijos skyriuose. Metodai ir rezultataiIšliekant žymiam atotrūkiui tarp organų pasiūlos ir poreikio, būtina kuo efektyviau panaudoti esamus resursus, daugiau dėmesio skiriant tinkamai potencialaus organų donoro intensyviajai terapijai. Dėl smegenų mirties įvyksta sunkūs daugelio organizmui svarbių funkcijų sutrikimai: kraujotakos ir kvėpavimo sistemų, endokrininiai, elektrolitų balanso sutrikimai, hipotermija, koagulopatija ir intensyvus sisteminis uždegimo atsakas. IšvadosPasirinkta tinkama intensyviosios terapijos taktika galėtų padidinti transplantacijai tinkamų organų skaičių, išlaikyti geresnę jų funkciją po transplantacijos. Reikšminiai žodžiai: smegenų mirtis, intensyviosios terapijos skyriai, audinių ir organų donorystė, gairės Organ donor management in the intensive care unit Viktorija Černiauskienė, Monika Čiplytė, Saulius VosyliusClinic of Anaesthesiology and Intensive Care, Vilnius University,Šiltnamių Str. 29, LT-04130 Vilnius, LithuaniaE-mail: [email protected] Background / objectiveThe demand for donor organs greatly exceeds the number of transplantations. Many reasons may determine this inadequacy, such as family refusal, medical contraindications, logistics problems and inadequate management of the organ donor. The aim of the study was to present the recent achievements of medical practice in the management of organ donors in intensive care units. Methods and resultsWhile the discrepancy between the number of organ donations and transplantations persists, it is essential to use available resources more effectively, paying more attention to the intensive care management of the organ donor. Many physiological changes follow after brain death, such as cardiovascular and pulmonary dysfunction, endocrine and homeostasis disturbances, hypothermia, coagulopathy and an enhanced inflammatory response. ConclusionsOptimal intensive care could increase the number of organs available for transplantation and improve their function after it. Keywords: brain death, intensive care units, tissue and organ procurement, guidelines as topic


2018 ◽  
Vol 12 (1) ◽  
pp. 51
Author(s):  
Débora Sampaio Pierot Cunha ◽  
Jefferson Abraão Caetano Lira ◽  
Gabriel Vitor De Sousa Campelo ◽  
José Francisco Ribeiro ◽  
Francisca Aline Amaral Da Silva ◽  
...  

RESUMOObjetivo: avaliar o conhecimento dos profissionais da saúde que atuam na Unidade de Terapia Intensiva acerca do diagnóstico de morte encefálica e da manutenção de órgãos em potenciais doadores. Método: estudo quanti-qualitativo, avaliativo, descritivo e exploratório, realizado com 21 profissionais da saúde em um hospital de referência. Os dados foram coletados com um questionário e submetidos à Técnica de Análise de Conteúdo, na modalidade Análise Categorial. Resultados: duas categorias emergiram após a análise << Conhecimento sobre a manutenção de órgãos >> e <<Conhecimento sobre o protocolo de morte encefálica >>. Conclusão: os profissionais intensivistas apresentaram conhecimento adequado sobre o protocolo de morte encefálica, entretanto, capacitações enfocando a manutenção de órgãos e as contraindicações para transplantes devem ser realizadas no intuito de possibilitar maior qualificação profissional e elevar o número de doadores efetivos. Descritores: Morte Encefálica; Obtenção de Tecidos e Órgãos; Transplantes; Unidades de Terapia Intensiva; Protocolos; Enfermagem.ABSTRACT Objective: to evaluate the knowledge of the health professionals who work in the Intensive Care Unit on the diagnosis of brain death and the maintenance of organs in potential donors. Method: quantitative-qualitative, evaluative, descriptive and exploratory study with 21 health professionals in a referral hospital. The data were collected with a questionnaire and submitted to the Content Analysis Technique, in the Categorical Analysis modality. Results: two categories emerged after the analysis << Knowledge about organ maintenance >> and << Knowledge about the brain death protocol >>. Conclusion: Intensivist professionals presented adequate knowledge about the brain death protocol, however, training focusing on organ maintenance and contraindications for transplantation should be carried out to provide a higher professional qualification and increase the number of effective donors. Descriptors: Brain Death; Tissue and Organ Procurement; Transplants; Intensive Care Units; Protocols; Nursing.RESUMEN Objetivo: evaluar el conocimiento de los profesionales de la salud que actúan en la Unidad de Terapia Intensiva acerca del diagnóstico de muerte encefálica y del mantenimiento de órganos en potenciales donantes. Método: estudio cuantitativo cualitativo, evaluativo, descriptivo y exploratorio, realizado con 21 profesionales de la salud en un hospital de referencia. Los datos fueron recolectados con un cuestionario y sometidos a la Técnica de Análisis de Contenido, en la modalidad Análisis Categorial. Resultados: dos categorías emergieron después del la análisis << Conocimiento sobre el mantenimiento de órganos >> y << Conocimiento sobre el protocolo de muerte encefálica >>. Conclusión: los profesionales intensivistas presentaron conocimiento adecuado sobre el protocolo de muerte encefálica, sin embargo, las capacitaciones enfocando el mantenimiento de órganos y las contraindicaciones para trasplantes deben ser realizadas, con el fin de posibilitar mayor calificación profesional y elevar el número de donantes efectivos. Descriptores: Muerte Encefálica; Obtención de Tejidos y Órganos; Trasplantes; Unidades de Cuidados Intensivos; Protocolos; Enfermería.


2019 ◽  
Vol 86 (4) ◽  
pp. 285-296
Author(s):  
Stephen E. Doran ◽  
Joseph M. Vukov

Prolonged survival after the declaration of death by neurologic criteria creates ambiguity regarding the validity of this methodology. This ambiguity has perpetuated the debate among secular and nondissenting Catholic authors who question whether the neurologic standards are sufficient for the declaration of death of organ donors. Cardiopulmonary criteria are being increasingly used for organ donors who do not meet brain death standards. However, cardiopulmonary criteria are plagued by conflict of interest issues, arbitrary standards for candidacy, and the lack of standardized protocols for organ procurement. Combining the neurological and cardiopulmonary standards into a single protocol would mitigate the weaknesses of both and provide greater biologic and moral certainty that a donor of unpaired vital organs is indeed dead. Summary: Before a person’s organs can be used for transplantation, he or she must be declared “brain-dead.” However, sometimes when someone is declared brain-dead, that person can be maintained on life-support for days or even weeks. This creates some confusion about whether the person has truly died. For patients who have a severe neurologic injury but are not brain-dead, organ donation can also occur after his or her heart stops beating. However, this protocol is more ambiguous and lacks standardized protocols. We propose that before a person can donate organs, he or she must first be declared brain-dead, and then his or her heart must irreversibly stop beating before organs are taken.


2021 ◽  
Author(s):  
Yuki Itagaki ◽  
Mineji Hayakawa ◽  
Kunihiko Maekawa ◽  
Akira Kodate ◽  
Koyo Moriki ◽  
...  

Abstract Background A shortage of donor organs amid a high demand for transplantable organs is a worldwide problem, and an increase in organ donation would be welcomed by the global healthcare system. Patients with brain death (BD) are potential organ donors, and early prediction of BD patients may facilitate the process of organ procurement. Therefore, we developed a model for early prediction of BD in patients who survived the initial phase of out-of-hospital cardiac arrest (OHCA). Methods We retrospectively analysed data of patients aged, who were aged < 80 years, experienced OHCA with return of spontaneous circulation (ROSC), and were admitted to our hospital between 2006 and 2018. We categorised the patients into either a non-BD or BD group. Demographic and laboratory data on emergency department admission were used for stepwise logistic regression. Prediction scores of BD after OHCA were based on β-coefficients of prognostic factors identified in the multivariable logistic model. Results Overall, 419 OHCA patients with ROSC were admitted to our hospital during the study period. Seventy-seven patients showed BD (18.3%). Age and OHCA aetiology were significantly different between the groups. Logistic regression analysis confirmed that age, low-flow time, pH, and aetiology were independent predictors of BD. The area under the receiver operating characteristic curve for this model was 0.831 (95% CI, 0.786–0.876). Conclusion We developed and internally validated a new prediction model for BD after OHCA, which could aid in early identification of potential organ donors for early donor organ procurement.


2020 ◽  
Vol 3 (3) ◽  
Author(s):  
Ricardo Gobato ◽  
Alireza Heidari

An “explosive extratropical cyclone” is an atmospheric phenomenon that occurs when there is a very rapid drop in central atmospheric pressure. This phenomenon, with its characteristic of rapidly lowering the pressure in its interior, generates very intense winds and for this reason it is called explosive cyclone, bomb cyclone. With gusts recorded of 116 km/h, atmospheric phenomenon – “cyclone bomb” (CB) hit southern Brazil on June 30, the beginning of winter 2020, causing destruction in its influence over. One of the cities most affected was Chapecó, west of the state of Santa Catarina. The satellite images show that the CB generated a low pressure (976 mbar) inside it, generating two atmospheric currents that moved at high speed. In a northwest-southeast direction, Bolivia and Paraguay, crossing the states of Parana and Santa Catarina, and this draft that hit the south of Brazil, which caused the destruction of the affected states.  Another moving to Argentina, southwest-northeast direction, due to high area of high pressure (1022 mbar). Both enhanced the phenomenon.


1970 ◽  
Vol 4 (4) ◽  
pp. 49-60
Author(s):  
Camila Dorilêo Negretti ◽  
Pablo Girardeli Mendonça Mesquita ◽  
Nilo César do Vale Baracho

Objetivo: Determinar o perfil epidemiológico dos pacientes com Doença Renal Crônica em tratamento conservador no ambulatório do Hospital Escola de Itajubá. Materiais e Métodos: Estudo descritivo, de corte transversal, de abordagem quantitativa. Realizado com 171 pacientes atendidos em tratamento conservador no ambulatório de nefrologia no período de janeiro de 2012 a dezembro de 2013. A coleta objetivou caracterizar idade, sexo, raça, estado civil e procedência. Também foram avaliados dados do primeiro atendimento como: valores de ureia e creatinina, o grau de DRC, a etiologia e o número de retorno. Resultados: Dos doentes renais crônicos avaliados, 50,3% eram do sexo masculino, 88% da raça branca, 54,4% casados e a maioria (70,8%) possuía faixa etária prevalente >60 anos. A maioria dos atendidos, 98,5% pertence a microrregião de referência. Quanto a dados de primeira consulta, o diabetes mellitus foi a principal etiologia (38%). Os valores de ureia e creatinina acima da referência preconizada foi observado na maioria dos pacientes e o grau III de DRC em 31% dos casos. O número médio de retornos após a primeira consulta foi de três retornos em 25,13% dos pacientes. Conclusão: A pesquisa permitiu o conhecimento do perfil epidemiológico dos portadores de DRC em tratamento conservador. Os achados reforçam a necessidade de implementação de políticas voltadas para promoção e prevenção à saúde com divulgação de mais programas de controle para minimizar o surgimento de novos casos da DRC. Palavras-chave: Epidemiologia. Doença Renal Crônica. Tratamento. ABSTRACT.Objective: Determine the epidemiological profile of patients with Chronic Kidney Disease (CKD) on conservative treatment at the Hospital Escola de Itajubá. Materials and Methods: A retrospective, descriptive, cross-sectional study of quantitative approach. It was conducted with 171 patients who were treated in conservative treatment at the nephrology clinic from January 2012 to December 2013. The collection aimed to characterize age, sex, race, marital status and origin. We also evaluated data from the first service as: urea and creatinine values, the degree of CKD the etiology and the number of return. Results: Among the chronic renal patients evaluated, 50.3% were male, 88% Caucasian, 54.4% were married and the majority (70.8%) was the most prevalent age group> 60 years. Most of the patients 98.5% belong to micro region of reference. As the first appointment data, diabetes mellitus was the major cause (38%). The urea and creatinine values above the recommended reference was observed in the majority of patients and the DRC grade III in 31% of cases. The average number of returns after the fisrt visit was three return in 25.13% of patients. Conclusion: The research gave us the knowledge of the epidemiological profile of patients with CKD on dialysis. The findings reinforce the need to implement policies for health promotion and prevention with more disclosure of control programs to minimize the appearance of new cases of CKD. Keywords: Epidemiology. Chronic Kidney Disease.Treatment.


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