scholarly journals LEMON AROMATHERAPY AS AN ALTERNATIVE TO REDUCE THE INTENSITY OF CHEMOTHERAPY-RELATED NAUSEA AND VOMITING EXPERIENCED BY THE BREAST CANCER PATIENTS

Author(s):  
Puji Hastuti ◽  
Yuli Nurhayati ◽  
Dwi Ernawati ◽  
Christina Yuliastuti ◽  
Merina Widyastuti

ABSTRACT Introduction : The mechanism of breast cancer is the cells growing and breeding become appear abnormal tissue of breast. One of the common treatments for it is chemotherapy using cytotoxic drugs. However, chemotherapy may cause nausea and vomiting as its side effects. Lemon aromatherapy is a complementary therapy in patients with breast cancer who experience nausea or vomiting. The study’s purpose was to know the effect of lemon aromatherapy on the intensity of nausea and vomiting experienced by the breast cancer patients as an effect of chemoterapy in the Chemo Center Room of RSAL Dr. Ramelan Surabaya. Material and Methods : The study was the pre-experimental design with pre-post test without control group. There are two variables, lemon aromatherapy is independent, and the intensity of nausea and vomiting is dependent. The sampling technique was nonprobability purposive sampling, with 34 breast cancer patients taken as the sample. A questionnaire was the instrument for collecting the data. The Data collected were analyzed using the Wilcoxon Test (α = 0,05). Results : The study’s result indicated that the lemon aromatherapy was effectively to decrease of the intensity of nausea and vomiting exeperienced by the respondents, with the value of Wilcoxon test p < 0.001. Conclusion : Lemon aromatherapy stimulates the raphe nucleus to produce serotonin. Which function to generate a sense of comfort and calm. For that reason, it can be used as an alternative for taking care of nausea and vomiting experienced by patients with breast cancer as the side effect of chemotherapy. Keywords:  Lemon Aromatherapy, Nausea, Vomiting, Chemotherapy  

2021 ◽  
pp. 1-5
Author(s):  
Yuliana Syam ◽  
Prihantono Prihantono ◽  
Elly L. Sjattar ◽  
Arnis Puspitha ◽  
Sintawati Majid

OBJECTIVE: The purpose of this study is to determine the effect of Apis dorsata Honey as a complementary therapy on IL-37 levels and fatigue in breast cancer patients undergoing chemotherapy. METHOD: The study used a quasi-experimental pretest-posttest design with a control group. A total of 30 subjects were recruited using a concurrent sampling technique. The intervention group consisted of 15 subjects who received oral honey at a dose of 13 ml (1 tablespoon × 3) for 15 days, and the control group consisted of 15 subjects. The groups’ samples were chosen at random. The Fatigue Symptom Inventory (FSI) was used to assess the side effects of chemotherapy. RESULTS: Although the effect of Apis dorsata Honey on IL-37 levels was not statistically significant (p > 0.05), the group given honey experienced a clinically significant increase in IL-37 levels, with a mean before (632.37514.93) and post (632.37514.93). (1,003.021,248.88). Fatigue decreased statistically significantly in the group given mean honey values prior to 13.205.59 and after 11.805.07 (p = 0.004). CONCLUSION: Honey administration increases IL-37 levels clinically, though the increase is not statistically significant. Giving honey to patients with breast cancer can help alleviate fatigue caused by chemotherapy.


2019 ◽  
Vol 6 (3) ◽  
pp. 401-407
Author(s):  
Anisa Ain ◽  
Desak Gede Agung ◽  
Esty Yunitasari

Background: Breast cancer is the most common type of cancer suffered by women. Cancer patients generally experience side effects of chemotherapy such as nausea and vomiting. Aim : The purpose of this study was to determine the effect of aromatherapy on nausea and vomiting of breast cancer patients undergoing chemotherapy. Method: this study is a true experimental study with a randomized pre-post-test design with a control group. The study sample was breast cancer patients with one day care chemotherapy at RSUD dr. Soetomo Surabaya. The sample was divided into 2 groups, the aromatherapy group (n = 20) and the control group (n = 20) collected consecutively in August to September 2019. Inhalation lavender aromatherapy is performed independently by patients at home every 2 times a day for 3 consecutive weeks (21 days). The instrument measures nausea and vomiting using the Rhodes Index Nausea, Vomiting and restcing. data analysis using paired t test. Results: The aromatherapy group had a mean difference of pre-post test -9.20, higher than the control group 0.30. Paired t test showed that there were significant differences in mean pre and post test in the aromatherapy group with p value <0.001 compared to the control group p 0.741 (> 0.05). Conclusion: lavender aromatherapy inhaled continuously for three consecutive weeks can reduce the nausea and vomiting of breast cancer patients undergoing chemotherapy


2018 ◽  
Vol 6 (2) ◽  
pp. 157-164
Author(s):  
Endah Fatma

2021 ◽  
Vol 15 (1) ◽  
pp. 1-7
Author(s):  
Sapti Ayubbana ◽  
Uswatun Hasanah

The effectiveness of peppermint aromatherapy on nausea and vomiting among breast cancer patients undergoing chemotherapyBackground: Breast cancer is a type of cancer and is one cause of death in the world. Chemotherapy is the use of chemical agents to control and destroy cancerous cells. Chemotherapy can induce nausea and vomiting, resulting in discomfort. One intervention that makes patients feel comfortable is giving peppermint aromatherapy.Purpose: To determine the effectiveness of peppermint aromatherapy on nausea and vomiting among breast cancer patients undergoing chemotherapy.Method: A quasi-experimental pretest-posttest group design, with a purposive sampling method of collecting samples. The study sample was 34 breast cancer patients who underwent chemotherapy. The sample divided into 2 groups as intervention & control groups. Measurement of nausea and vomiting used the Rhodes Index Nausea Vomiting & Retching (INVR) instrument.Results: Finding by the Man Whitney test, it showed that there was a difference in the scores for nausea and vomiting between the intervention group and the control group (p value = 0.008).Conclusion: Peppermint aromatherapy is effective in reducing nausea and vomiting among breast cancer patients undergoing chemotherapy.Keywords: Breast cancer; Chemotherapy, Nausea; Vomiting; Peppermint aromatherapyPendahuluan: Kanker  payudara  merupakan salah satu  jenis kanker dan menjadi salah satu penyebab kematian di dunia.  Kemoterapi merupakan penggunaan agen kimiawi untuk mengontrol dan  menghancurkan sel yang bersifat kanker.Kemoterapi dapat menginduksi mual dan muntah mengakibatkan ketidaknyamanan. Salah satu intervensi yang membuat pasien merasa nyaman adalah dengan pemberian aromaterapi pepermint.Tujuan: Mengetahui efektifitas aromaterapi pepermint terhadap mual muntah pada pasien kanker payudara yang menjalani kemoterapi.Metode : Penelitian quasi experimental pretest-posttest group design, dengan metode pengumpulan sampel secara purposive sampling. Sampel penelitian sebanyak 34 pasien kanker payudara yang menjalani kemoterapi. Sampel terbagi atas dua kelompok; intervensi & kontrol. Pengukuran mual muntah menggunakan instrumen Rhodes Index Nausea Vomiting & Retching ( INVR).Hasil :  Dengan menggunakan man whitney test menunjukkan bahwa terdapat perbedaan skor mual muntah antara kelompok intervensi dengan kelompok kontrol  (p value = 0,008).Simpulan: Aromaterapi peppermint efektif menurunkan mual muntah pada pasien kanker kayudara yang menjalani kemoterapi.


2020 ◽  
Vol 7 (2) ◽  
pp. 398-402
Author(s):  
Sugih Wijayati ◽  
Suci Abrelia Fitriyanti ◽  
Arwani Arwani

Latar Belakang: Reaksi psikologis yang dapat muncul setelah pasien didiagnosis kanker serviks pada umumnya merasa shock mental, takut, tidak bisa menerima kenyataan, sampai pada keadaan depresi. Depresi berdampak pada gangguan mood yang dikarakteristikkan dengan kesedihan yang intens, berlangsung dalam waktu lama, dan mengganggu kehidupan normal.Kondisi ini terjadi pada pasien kanker servix .Salah satu terapi  komplementer yang dapat digunakan untuk menurunkan tingkat depresi pada pasien kanker servix yaitu terapi Spiritual Emotional Freedom Technique (SEFT).Salah satu dampak depresi  yang akan muncul adalah lemahnya kondisi fisik yang akan menghambat proses pengobatan dan mendukung sel kanker servix semakin berkembang. Tujuan:  untuk mengetahui pengaruh terapi SEFT terhadap tingkat depresi pada pasien kanker serviks di RSUD Dr. Moewardi Surakarta.  Metode: Jenis penelitian ini adalah penelitian pra – eksperimental dengan desain penelitian pre and post-test without control group. Sampel dalam penelitian ini sebanyak 33 responden dengan teknik consecutive sampling. Uji analisis data dengan uji Wilcoxon – test. Hasil:  Hasil penelitian menunjukkan penurunan skor depresi dari 28 (depresi sedang) menjadi 20 (depresi klinis) setelah dilakukan SEFT dan perubahan skor depresi secara statistik bermakna (p = 0,000). Kesimpulan: ada penurunan terapi SEFT terhadap tingkat depresi pada pasien kanker serviks. Kata kunci : depresi , SEFT, kanker serviks.   Abstract Background : Psychological reactions commonly occur among cervical cancer patients are mental alteration, fear, denial and depression. Depression is a mood disorder characterized by prolonged sorrow, which can disrupt normal life.  The SEFT therapy is an effective complementary therapy to reduce depression level. Aims: This study aims to examine the effect of SEFT therapy on depression among cervical cancer patients at Dr. Moewardi Surakarta General Hospital. Methods:  A pre - experimental study using pre and post-test without control group design was applied to 33 respondents recruited by consecutive sampling method. The data were analyzed using the Wilcoxon test. Result: The depression score was decreased from 28 (moderate depression) to 20 (clinical depression) after intervention, which is statistically significant (p= 0.000). Conclusion : It is concluded that there is positive effect of  SEFT therapy on  depression level among  cervical cancer patients. Keyword : depression, SEFT. Cervical Cancer.                                                                           


2019 ◽  
Vol 47 (6) ◽  
pp. 2607-2614 ◽  
Author(s):  
Fujie Yu ◽  
Yuanmei Li ◽  
Jiaqun Zou ◽  
Lisha Jiang ◽  
Chun Wang ◽  
...  

Objective To investigate the effects of the Chinese herbal medicine Xiaoaiping to treat chemotherapy-induced side effects in breast cancer patients. Methods Ninety-three adult patients who attended our hospital and met the entry criteria from January 2016 to December 2017 were included. Patients were randomly divided into the control group (routine chemotherapy only) and the combined group (routine chemotherapy and Xiaoaiping). Demographic data and clinical variables were collected, and side effects including alopecia, nausea and vomiting, diarrhea, white blood cell (WBC) count, aspartate aminotransferase (AST) levels, and the quality of life were evaluated. Results Basic clinical characteristics were not different between the groups. There were significantly fewer patients with alopecia grade 3–4, but significantly more patients with alopecia grade 1–2, in the combined group compared with the control group. Disease-free time for alopecia was longer in the combined compared with the control group. Overall, the side effects were significantly more serious in the control compared with the combined group. Patients in the combined group had better quality of life than the control patients. Conclusion Xiaoaiping can improve alopecia, nausea and vomiting, and diarrhea symptoms, WBC count, AST levels, and the quality of life in breast cancer patients.


2020 ◽  
Vol 8 (4) ◽  
pp. 451
Author(s):  
Aric Frendi Andriyan ◽  
Arina Widya Murni ◽  
Rika Fatmadona

Early detection is the first step in breast cancer prevention which targets can be done during adolescence, early detection in adolescents needs to be done through peer educators because adolescents prefer information from peers rather than parents or teachers, so that the material presented can improve BSE knowledge and attitude. This study aims to determine the effect of peer health education regarding knowledge and attitudes of BSE. The research design used a quasi-experimental study with a pre-post approach with a control group. Young women are the population in this study, with the sampling technique using purposive sampling. The sample used was 240 female teenage respondents according to the inclusion and exclusion criteria. Data collection using a questionnaire with Cronbach's alpha is 0.941> 0.7 for knowledge and 0.890 (> 0.361) for attitudes. Data analysis using the Wilcoxon test. The results showed that there was a difference between the pre-test median knowledge score was 14 and increased to 22 after the post-test with a P value of  0.000 <0.05 and the pre-test attitude median value was 17 increasing to 23 after the post-test with P Value 0.000 <0.05. Based on the research, it can be concluded that peers are very influential in increasing BSE knowledge and attitudes so that it is very important in early detection of breast cancer.


2021 ◽  
pp. 1-5
Author(s):  
Yuliana Syam ◽  
Prihantono Prihantono ◽  
Sintawati Majid ◽  
Elly L. Sjattar ◽  
Mery Kana ◽  
...  

BACKGROUND: The overproduction of interleukin-6 (IL-6) in breast cancer cases can aggravate metastases. In comparison, the production of T lymphocytes plays a role in suppressing the development of tumor cells. Honey as a complementary therapy is expected to reduce the overproduction of IL-6 and facilitate the production of T lymphocytes in breast cancer cases. OBJECTIVE: This study aims to determine the effect of Dorsata honey (DH) as a complementary therapy to IL-6 levels and T lymphocytes of post-chemotherapy in breast cancer. METHODS: This study was a quasi-experimental approach that employed a pretest-posttest group control design. As many as 30 post-chemotherapy breast cancer patients at the Central Hospital in Eastern Indonesia were randomly selected into a control group of 15 participants. Additionally, an intervention group of 15 participants was given DH orally three times a day at a dose of 15 ml. The blood sample was taken two times, day 0 of the chemotherapy and day 16 (post-chemotherapy). The level of IL-6 was measured by ELISA, while the data were analyzed by Wilcoxon, independent T-test, and Mann–Whitney test. RESULTS: The results showed that DH did not significantly affect IL-6 levels (p = 0.17). However, there was an increase in T lymphocyte levels with statistically significant differences (p = 0.01) in intervention groups. There was no difference in Il-6 and T lymphocyte levels between the intervention and control groups (p > 0.05). CONCLUSIONS: Il-6 levels tend to be constant in the intervention group. However, there is a significant increase in the T lymphocyte levels which can indirectly increase the immune system and inhibit tumor cell growth in patients with breast cancer.


2007 ◽  
Vol 125 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Claudio Battaglini ◽  
Martim Bottaro ◽  
Carolyn Dennehy ◽  
Logan Rae ◽  
Edgar Shields ◽  
...  

CONTEXT AND OBJECTIVE: Changes in metabolism have been reported in the majority of patients undergoing cancer treatment, and these are usually characterized by progressive change in body composition. The effects of aerobic exercise programs to combat the cancer and cancer treatment-related side effects, which include the negative changes in body composition, have been extensively reported in the literature. However, few resistance exercise intervention studies have hypothesized that breast cancer patients might benefit from this type of exercise. The purpose of this study was to determine whether exercise protocols that emphasize resistance training would change body composition and strength in breast cancer patients undergoing treatment. DESIGN AND SETTING: Randomized controlled trial, at the Campus Recreation Center and Rocky Mountain Cancer Rehabilitation Institute of the University of Northern Colorado, and the North Colorado Medical Center. METHODS: Twenty inactive breast cancer patients were randomly assigned to a 21-week exercise group (n = 10) or a control group (n = 10). The exercise group trained at low to moderate intensity for 60 minutes on two days/week. The primary outcome measurements included body composition (skinfold method) and muscle strength (one repetition maximum). RESULTS: Significant differences in lean body mass, body fat and strength (p = 0.004, p = 0.004, p = 0.025, respectively) were observed between the groups at the end of the study. CONCLUSION: The results suggest that exercise emphasizing resistance training promotes positive changes in body composition and strength in breast cancer patients undergoing treatment.


QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Abeer I Abd Elmagid ◽  
Hala Abdel Al ◽  
Wessam El Sayed Saad ◽  
Seham Kamal Mohamed

Abstract Background Breast cancer is the most common cancer among women and one of the most important causes of death among them.Angiogenesis is an important step for primary tumor growth, invasiveness, and metastases. Angiopoietins are well-recognized endothelial growth factors that are involved in angiogenesis associated with tumors. Aim To explore the diagnostic significance of serum angiopoietin-2 (Ang-2) in breast cancer and to evaluate its prognostic efficacy through studying the degree of its association with the TNM staging of the disease. Patients and Methods This study was conducted on (35) Egyptian female patients who were diagnosed as breast cancer according to histopathological examination of breast biopsy (Group 1, Breast Cancer Patients) and (25) female patients with benign breast diseases (Group II, Pathological Control Patients), in addition to (20) age - matched apparently healthy, free mammogram, females serving as healthy controls (Group III, Healthy Controls). For all participants, measurement of serum Ang-2 was done using enzyme linked immunosorbent assay (ELISA) technique. Results A highly significant increased levels of Ang-2 was observed in breast cancer patients when compared to healthy control group (Z = 4.95, p &lt; 0.01). However, no significant difference was observed in Ang-2 levels between breast cancer patients group and pathological control group (Z = 3.37, p &gt; 0.05). No significant difference was detected in Ang-2 levels in relation to TNM stage and histological grade. No significant correlation was found between Ang-2 levels and serum levels of CA15-3, hormone receptors, HER2/new receptor status (p &gt; 0.05, respectively). Conclusion This study revealed that Ang-2 serum levels were significantly increased in patient with breast cancer compared with healthy controls, indicating that high Ang-2 level is a promising non invasive biomarker for breast cancer diagnosis. However, no significant difference of Ang-2 levels was detected in relation of breast TNM staging in the population studied.


Sign in / Sign up

Export Citation Format

Share Document