scholarly journals The effect of TRX exercises on serum levels of IGF-1 and cortisol and some health-related physical factors in active women

2020 ◽  
Vol 30 (4) ◽  
pp. 432-442
Author(s):  
Soleyman Ansari Kolachahi ◽  
Alireza Elmieh ◽  
Mona Talebi ◽  
◽  
◽  
...  
2020 ◽  
Vol 80 (07) ◽  
pp. 723-732
Author(s):  
Sophie Strozyk ◽  
Klaus-Dieter Wernecke ◽  
Jalid Sehouli ◽  
Matthias David

Abstract Objectives The study aimed to answer a number of questions: Which medical, psychological and sociodemographic factors affect the recovery of women after gynecological surgery for benign indications? Does patientsʼ health-related quality of life improve after surgical intervention? How long are patients signed off work postoperatively? How do patients assess their own capacity to work? Method Study population: All women between the ages of 18 and 67 years who underwent gynecological surgery for benign indications at the Charité Campus Virchow Clinic over a 7-month period were consecutively enrolled in the study. Four standardized patient surveys (the first survey [T0] was carried out in hospital, T1 at 1 week, T2 at 6 weeks and T3 at 7 – 8 months after discharge by telephone interview) were carried out using evaluated questionnaires to record patientsʼ recovery (Recovery Index), quality of life (RAND-36), satisfaction, complications, sociodemographic information and time off work with a medical sick note. Relevant medical and demographic data were also collected. Statistical analysis was carried out using univariate statistical tests for descriptive analysis and complex multifactorial statistical procedures to record observations over time. Results A total of 182 patients were included in this study (participation rate: 70%). Relevant prior operations (p = 0.01), in-hospital (p = 0.004) and postoperative complications (p < 0.001), preoperative psychological wellbeing (p = 0.01), physical functioning (p = 0.005) and postoperative anxiety (p = 0,006) had a significant impact on recovery (Recovery Index) and changed significantly over time (p < 0.001). The invasiveness of the surgery or sociodemographic parameters (including migration background) had no significant effect. Health-related quality of life (measured with the RAND-36 questionnaire) also improved postoperatively. More invasive surgical interventions were associated with longer sick leave times and, to a certain extent, with a poorer evaluation of patientsʼ capacity to work. Conclusion Recovery after gynecological surgery is a multifactorial process. This survey of a patient population identified psychological and physical factors which influence recovery but did not find significant sociodemographic parameters affecting recovery. Irrespective of these findings, gynecological surgery for benign indications resulted in an improvement in health-related quality of life. Prospective studies need to investigate whether psychological interventions could reduce preoperative fear and thereby improve postoperative recovery.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 824-825
Author(s):  
Sumi Lee ◽  
JuHee Lee

Abstract Objectives This study aimed to explore the risk factors associated with cognitive frailty(CF) among community-dwelling older adults, and to provide the impact of CF on health-related outcomes. Methods PubMed, EMBASE, Cochrane, PsycINFO, CINAHL, RISS, DBpia, NDSL, and KoreaMed databases were searched to retrieve studies. Two reviewers independently screened titles, abstracts and articles. The inclusion criteria are peer-reviewed articles written in English or Korean for community-dwelling older adults with both physical frailty and cognitive impairment present at the same time. Results A total of 3,513 were searched, and the final 33 were extracted according to the inclusion criteria. Physical factors affecting CF were the number of chronic disease, cardiovascular disease, activity of daily living(ADL), making telephone calls and shopping during instrumental ADL, and a Mini Nutrition Assessment–Short Form score. Psychological factor was depressive symptoms. Significant behavioral factors included self-reported physical activity, low vitamin D, smoking, frequent insomnia, and sedentary lifestyle. In social factors, social participation such as volunteering was identified as a protective factor. Mortality, followed by dementia was health related outcomes on CF, including ADL dependence, poor quality of life, and hospitalization. However, the CF-related fall was inconsistent. Conclusion A wide variety of factors have been presented in studies related to CF. In order to understand CF and improve health-related outcomes, older adults in CF should be screened as high-risk group. When the risk factors and protective factors of CF managed, better health-related outcomes will lead to successful aging of community-dwelling older adults.


2009 ◽  
Vol 25 (10) ◽  
pp. 2159-2167 ◽  
Author(s):  
Margareth Guimarães Lima ◽  
Marilisa Berti de Azevedo Barros ◽  
Chester Luiz Galvão César ◽  
Moisés Goldbaum ◽  
Luana Carandina ◽  
...  

As life expectancy continues to rise, one of the greatest challenges of public health is to improve the quality of later years of life. The aim of this present study was to analyze the quality of life profile of the elderly across different demographic and socioeconomic factors. A cross-sectional study was carried out in two stages, involving 1,958 individuals aged 60 years or more. Health related quality of life (HRQOL) was assessed using the SF-36 questionnaire. The lowest scores were found among measures for vitality, mental health and general health and the highest among factors including social functioning and role limitations due to emotional and physical factors. HRQOL was found to be worse among women, in individuals at advanced ages, those who practiced evangelical religions and those with lower levels of income and schooling. The greatest differences in SF-36 scores between the categories were observed in functional capacity and physical factors. The results suggest that healthcare programs for the elderly should take into account the multi-dimensionality of health and social inequalities so that interventions can target the most affected elements of HRQOL as well as the most vulnerable subgroups of the population.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Yu-Jiung Lin ◽  
Imran Khan ◽  
Subhajit Saha ◽  
Chih-Cheng Wu ◽  
Snigdha Roy Barman ◽  
...  

AbstractThe highly reactive nature of reactive oxygen species (ROS) is the basis for widespread use in environmental and health-related fields. Conventionally, there are only two kinds of catalysts used for ROS generation: photocatalysts and piezocatalysts. However, their usage has been limited due to various environmental and physical factors. To address this problem, herein, we report thermoelectric materials, such as Bi2Te3, Sb2Te3, and PbTe, as thermocatalysts which can produce hydrogen peroxide (H2O2) under a small surrounding temperature difference. Being the most prevalent environmental factors in daily life, temperature and related thermal effects have tremendous potential for practical applications. To increase the practicality in everyday life, bismuth telluride nanoplates (Bi2Te3 NPs), serving as an efficient thermocatalyst, are coated on a carbon fiber fabric (Bi2Te3@CFF) to develop a thermocatalytic filter with antibacterial function. Temperature difference induced H2O2 generation by thermocatalysts results in the oxidative damage of bacteria, which makes thermocatalysts highly promising for disinfection applications. Antibacterial activity as high as 95% is achieved only by the treatment of low-temperature difference cycles. The current work highlights the horizon-shifting impacts of thermoelectric materials for real-time purification and antibacterial applications.


2021 ◽  
Vol 9 ◽  
Author(s):  
Luigi Di Lorenzo ◽  
Luigi Vimercati ◽  
Antonella Pipoli ◽  
Nicola Mariano Manghisi ◽  
Luisa Lampignano ◽  
...  

Introduction: Occupational physicians, as an aspect of the periodic health surveillance of workers prescribed by law, must develop preventive programs against adverse health-related occurrences (Legislative Decree 81/2008, art.25) to reduce major risk factors for non-communicable/chronic diseases. Eating habits play an important role in defining risk trajectories in the workplace.Methods: We randomly and cross-sectionally evaluated 147 females, of which 59 were healthcare workers (HCWs) and 88 were non-HCWs. The assessment included a dietary screening for adherence to the Mediterranean diet (MD) and a clinical baseline collection of major fluid biomarkers and anthropometric indicators for cardiovascular and metabolic risk.Results: The HCW group exhibited greater adherence to the MD than the non-HCW group. Nevertheless, they showed higher serum levels of triglycerides and total cholesterol. Menopause and type of work significantly and unfavorably affected triglyceride serum levels among HCWs.Conclusion: Greater preventive efforts are needed in the context of periodic health surveillance by occupational physicians. Disseminating additional information on a healthier lifestyle, particularly among female workers of perimenopausal age, is a key issue.


Background: High-intensity functional training can be well performed by the elderly; however, the effect of this training on brain-health-related factors has not been studied yet. Therefore, this study aimed to investigate the effect of eight weeks of high-intensity functional training on serum levels of BDNF, IGF-1, and VEGF in elderly men and women. Materials and Methods: This quasi-experimental study included 23 subjects (7 males and 16 females) who were divided into experimental (n=16) and control groups (n=7). The experimental group performed a training protocol consisting of six exercises in three sessions (each session was 25 min) per week for eight weeks. The exercises were performed at all-out intensity for 30 sec. There was a 15-sec rest between each set and a two-min rest between each exercise. Paired samples t-test and ANCOVA were used to analyze the data, and a p-value less than 0.05 was considered statistically significant. Results: The results showed that the serum levels of BDNF (P=0.0005, +11.37), VEGF (P=0.0005, +7.49), IGF-1 (P=0.001, +3.91), LDL (P=0.004, -3.33), and HDL (P=0.004, +7.48) changed significantly in the experimental group. On the other hand, in the control group, serum levels of BDNF (P=0.149, +1.58), IGF-1 (P=0.486, +0.27), LDL (P=0.897, +0.14), and HDL (P=0.534, +1.10) had no significant changes; however, VEGF (P=0.01, +0.67) significantly changed. The results of ANCOVA showed a significant difference between the two groups regarding all variables (P<0.05). Conclusion: Eight weeks of high-intensity functional training in elderly men and women increases the serum levels of brain health-related factors. Therefore, functional training is recommended to improve brain function in the elderly.


2020 ◽  
pp. 014556132091068
Author(s):  
Alicia Seethaler ◽  
Markus Stenner ◽  
Annika McNally ◽  
Claudia Rudack ◽  
Johannes Roth ◽  
...  

Objectives: Tonsillectomy (TE) and tonsillotomy (TO) due to recurrent episodes of acute tonsillitis (RAT) belong to the most frequent surgical procedures. However, an adequate objective marker predicting the outcome of TE/TO preoperatively is missing. Methods: Patients with RAT who underwent TE/TO (n = 31) were included in this pilot study. A panel of cytokines and chemokines in serum and saliva were determined preoperatively. Health-related quality of life was assessed pre- and postoperatively by the Tonsillectomy Outcome Inventory-14. Results: Health-related quality of life improved significantly after surgery. Increased serum levels of interleukin-8 (IL-8) and interferon gamma (IFN-γ) are associated with a less successful outcome. No correlation between the number of acute tonsillitis episodes and the health-related quality of life after TE or TO could be observed. Conclusions: Tonsillectomy and TO improve health-related quality of life independently from the number of past acute tonsillitis episodes. Interleukin-8 and IFN-γ in serum may serve as promising markers, predicting the benefit of TE or TO for patients preoperatively.


Cells ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 2471
Author(s):  
Philipp Burow ◽  
Marc Haselier ◽  
Steffen Naegel ◽  
Leila Motlagh Scholle ◽  
Charly Gaul ◽  
...  

Mitochondrial processes may play a role in the pathophysiology of migraine. Serum levels of two biomarkers, Fibroblast-growth-factor 21 (FGF-21) and Growth-differentiation-factor 15 (GDF-15), are typically elevated in patients with mitochondrial disorders. The study investigated whether the presence of migraine may influence FGF-21 and GDF-15 serum levels considering vascular and metabolic disorders as possible confounders. A cross-sectional study in two headache centers was conducted analyzing GDF-15 and FGF-21 serum concentration in 230 patients with episodic and chronic migraine compared to a control group. Key clinical features of headache were evaluated, as well as health-related life quality, anxiety and depression using SF-12 and HADS-questionnaires. Elevated GDF-15 values were detected in the migraine group compared to the control group (506.65 ± 275.87 pg/mL vs. 403.34 ± 173.29 pg/mL, p < 0.001, Mann–Whitney U test). A strong correlation between increasing age and higher GDF-15 levels was identified (p < 0.001, 95%-CI elevation of GDF-15 per year 5.246–10.850 pg/mL, multiple linear regression). Mean age was different between the groups, and this represents a confounding factor of the measurements. FGF-21 levels did not differ between migraine patients and controls (p = 0.635, Mann–Whitney U test) but were significantly influenced by increasing BMI (p = 0.030, multiple linear regression). Neither biomarker showed correlation with headache frequency. Higher FGF-21 levels were associated with a higher mean intensity of headache attacks, reduced health-related life quality and anxiety. When confounding factors were considered, increased serum levels of FGF-21 and GDF-15 were not detected in migraine patients. However, the results show an age-dependence of GDF-15 in migraine patients, and this should be considered in future studies. Similar findings apply to the relationship between FGF-21 and BMI. Previous studies that did not adjust for these factors should be interpreted with caution.


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