scholarly journals JERVELL AND LANGE-NIELSEN SYNDROME

2011 ◽  
Vol 18 (04) ◽  
pp. 638-643
Author(s):  
AMMAR ANWER ◽  
ALI SHAKEEL ◽  
M. HAMAYUN IKRAM ◽  
Shahroona Masud Zaman
Keyword(s):  
School Children ◽  
Deaf Children ◽  
Control Group ◽  
Qtc Interval ◽  
Healthy Children ◽  
Impaired Hearing ◽  
Cross Sectional ◽  
Cousin Marriage ◽  
Consanguineous Marriages ◽  
Deaf School

Objective: This study was carried out to find out the prevalence of Jervell and Lange Nielsen Syndrome (JLNS) in deaf school children for impaired hearing and to correlate this with consanguineous marriages. Setup: Schools for deaf and dumb children and Sheikh Zayed Medical College, Rahim Yar Khan. Design: Cross sectional, case control study. Period: 2006 - 2007. Methods: Electrocardiographs (ECG’s) of 114 congenitally deaf school children (ages 4-20 years) and also of 23 healthy children with normal hearing function of same age group were recorded. The corrected QT (QTc) interval of all 137 ECGs was evaluated by Bazett’s formula. Mean QTc of healthy children was taken as reference of normal QTc interval. The deaf children with normal QTc were labeled as control group. Patients with long QTc were further evaluated for JLNS by applying Schwartz’s criteria. We also calculated the relationship of the positive cases to consanguineous marriages. Results: We found that 28 deaf children out of 114 cases had QTc intervals longer than 0.44 seconds. This interval was significantly longer [P=0.008] than the QT interval in control group. As per Schwartz’s criteria, 15 out of 28 LQTs cases scored high points (3.5 to 5.5). The presence of consanguineous marriage was 100% in first pedigree of these 28 children. Conclusions: JLNS (an alarming arrhythmic disease associated with congenital deafness) is significantly present (24.6%) in Rahim Yar Khan’s deaf school children. The presence of cousin marriage was 100% in first pedigree of these children.

scholarly journals Health and nutritional status of school children from a rural area of Andhra Pradesh

2020 ◽  
Vol 7 (9) ◽  
pp. 1869
Author(s):  
Nanditha G. ◽  
Chandrakala R. Iyer ◽  
Chandrashekar M. A. ◽  
Poojitha Kancherla ◽  
Raghuveer Golluri ◽  
...  
Keyword(s):  
Health Status ◽  
Nutritional Status ◽  
School Children ◽  
Respiratory Infections ◽  
Good Health ◽  
Cross Sectional Study ◽  
Health Problems ◽  
Healthy Children ◽  
Cross Sectional ◽  
Health Programmes

Background: Healthy children build a wealthy nation. Good health of children is of paramount importance to the nation’s growth. Health and nutritional status of school children is highly variable from one region to another due to different environmental, socioeconomic and cultural factors. Hence health status of school children from each area should be assessed periodically so that relevant health programmes can be applied to prevent common morbidities such as malnutrition, infections and infestations. Methods: A cross sectional study of 500 rural school children from 5 to 15 years was conducted to assess the nutritional status by anthropometry and health status by clinical examination.Results: Out of the 500 school children 46.8% girls, 71.4% were 5 to 10 years old, 70.2% studying in 1st to 5th class.  33.4% were stunted. 25.6% and 27% were underweight according to weight and Body mass index criteria respectively. Common health problems among school children in this study were anemia (31%), dental caries (27.2%), upper respiratory infections (13.4%), skin infections and scabies (12.6%), head lice infestation (6.8%), refractive errors (6%) and ear discharge (5.2%).Conclusions: Though the pattern of nutritional and health problems were same in different studies, the severity of them varied from region to region. Hence periodic screening of school children to identify them and to apply relevant health programmes goes a long way in reducing such morbidities.

scholarly journals THE IMPACT OF ASTHMAAND ITS MEDICATIONS ON DENTAL CARIES STATUS AND STREPTOCOCCUS MUTANS COUNT IN CHILDREN: A CROSS-SECTIONAL STUDY

2020 ◽  
pp. 20-23
Author(s):  
Sneha Upadhyay ◽  
Jyoti Bhavthankar ◽  
Mandakini Mandale ◽  
Nivedita Kaorey
Keyword(s):  
Dental Caries ◽  
Streptococcus Mutans ◽  
Cross Sectional Study ◽  
Control Group ◽  
Healthy Children ◽  
Sectional Study ◽  
Cross Sectional ◽  
Asthmatic Children ◽  
Significant Difference ◽  
The Impact

Background: Asthma and its medications have been linked to oral diseases in asthmatic children. Aim: Assessment of the dental caries status, salivary Streptococcus mutans count and S. mutans colony score in children receiving inhaled anti asthmatic medications and their comparison in healthy children Material and Method: A cross-sectional study was performed on 40 asthmatic children and 40 healthy children in the age group of 6-14 years. DMFT/deft indices were calculated and saliva samples were collected. Diluted saliva was inoculated on MSB agar plates. S. mutans count and colony score were analysed after 24-48 hours of inoculation. Results: Statistically significant difference was observed in the mean DMFT/deft index, salivary S. mutans load and S. mutans colony score in children of the asthmatic group and control group. Conclusion: Prevalence of dental caries and cariogenic bacteria is higher in asthmatic children.

scholarly journals Physical Activity Practice and Optimal Development of Postural Control in School Children: Are They Related?

2020 ◽  
Vol 9 (9) ◽  
pp. 2919 ◽  
Author(s):  
Jose L. García-Soidán ◽  
Jesús García-Liñeira ◽  
Raquel Leirós-Rodríguez ◽  
Anxela Soto-Rodríguez
Keyword(s):  
Physical Activity ◽  
Postural Control ◽  
School Children ◽  
Cross Sectional Study ◽  
The Body ◽  
Healthy Children ◽  
Sectional Study ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Control State

Background: This study aims to analyze the effect of physical activity practice on the postural control state of school children. If such an effect was detected, the second aim of the study was to identify which specific capacities of postural control benefited the most from physical activity. Methods: A cross-sectional study was performed using a convenience sample of 118 healthy children (54 girls) with a mean age of 10.3 ± 1.2 years. Their weight and height were measured. The accelerometric assessment of balance included four different tests in static balance and walking. Results: Physical activity habit prevalence was 38.9% in girls and 60.9% in boys, and its frequency was 2.3 days per week in girls and 2.8 days in boys. The active children obtained lower accelerations, but the active and sedentary girls showed lower accelerometric values than the active boys. The logistic regression analysis demonstrated the influence of sex on the accelerations of the body (p < 0.001), regardless of the habit of physical activity. Conclusions: Active children have better postural control than sedentary children, although sedentary girls have better balance than active boys. Therefore, physical activity practice seems to favor a more efficient development of postural control, but it cannot level or reverse the effect of the neurophysiological factors that are conditioned by sex.

Decreased Pain Threshold in Juvenile Idiopathic Arthritis: A Cross-sectional Study

2013 ◽  
Vol 40 (7) ◽  
pp. 1212-1217 ◽  
Author(s):  
Anne Leegaard ◽  
Johanne Jeppesen Lomholt ◽  
Mikael Thastum ◽  
Troels Herlin
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Pain Threshold ◽  
Pain Perception ◽  
Negative Control ◽  
Control Group ◽  
Healthy Children ◽  
Cross Sectional ◽  
Age Related ◽  
Digital Pressure ◽  
Pressure Algometer

Objective.To examine the pain threshold in children with juvenile idiopathic arthritis (JIA) compared with healthy children by using a digital pressure algometer.Methods.Fifty-eight children with JIA born between 1995 and 2000 and 91 age-related healthy children participated in the study. We used a digital pressure algometer to measure the pain threshold on 17 symmetric, anatomically predefined joint-related or bone-related areas. All children were asked to rate their current pain on a Faces Pain Scale, and parents of children with JIA were asked to complete a parental revised version of the Child Health Assessment Questionnaire (CHAQ-R). Clinical data were registered on children with JIA.Results.The pain threshold was significantly lower among children with JIA (total mean PT = 1.33 ± 0.69 kg/cm2) when compared with the healthy control group (total mean PT = 1.77 ± 0.67 kg/cm2). The same pattern was found in all areas measured, including negative control areas that are normally unaffected in JIA (p = 0.0001 to 0.005). Overall, the pain threshold was 34% lower in females than in males in both groups (p < 0.0001). We found no correlation between pain threshold and age, current pain experience, disease duration, or disease activity.Conclusion.Children with JIA had a substantially lower pain threshold even in areas usually unaffected by arthritis. Our findings suggest that JIA alters the pain perception and causes decreased pain threshold.

scholarly journals HEARING EVALUATION OF NIGERIAN PRISON INMATES: A CROSS-SECTIONAL SURVEY

2020 ◽  
Vol 14 (2) ◽  
pp. 106-114
Author(s):  
Abdullahi Musa Kirfi ◽  
◽  
Mohammed Bello Fufore ◽  
Garba Mohammed Mainasara ◽  
Abdulrazak Ajiya ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Pure Tone ◽  
Hearing Threshold ◽  
Pure Tone Audiometry ◽  
Control Group ◽  
Prison Inmates ◽  
Impaired Hearing ◽  
Cross Sectional ◽  
The Mean ◽  
The Right

Background: Prisoners, due to confinement are isolated from contact with the society and access to many of the facilities, including medical care. This study aimed to evaluate the hearing threshold of inmates of Kaduna convict prison. Method: It was a cross-sectional study of prison inmates at the Kaduna convict prison between April 2017 and February 2019. Ethical approvals were obtained from relevant bodies and all consented inmates aged 18 – 55years in the Kaduna convict prison were enrolled. Equal number of control matched for age and gender were enrolled from the communities in Kaduna North Local Government Area. Data were collated using a structured questionnaire. A diagnostic Pure Tone Audiometry was performed to assess their hearing threshold. Statistical Package for Social Sciences (SPSS) version 20.0 was used for analysis. Results: Four hundred and thirty inmates and equal number of control group were enrolled. The mean age for the inmates and controls were 30.2±7.5 and 30.4±8.02 years respectively. There were 383 males and 47 females in both groups. Among the 860 ears of the inmates, 238(27.7%) ears had hearing loss while in the control group, 95/ (11.1%) ears had impaired hearing. Conductive hearing loss was the commonest among the inmates 111(46.6%) while sensorineural was commoner among the controls 57(60.0%). The mean pure tone average among the inmates was 25.6±11.3dBHL and 26.1±11.2dBHL on the right and left ears respectively while in the control group, it was 18.4±7.8dBHL on the right and 17.9±7.9dBHL on the left. Conclusion: This study revealed that hearing loss was more prevalent among prison inmates than the general population. In majority of the inmates, the hearing loss was mild, conductive and mostly affecting all the frequencies.

Evaluation of Serum Level of Carnitine in Children with Acute Pyelonephritis (APN) Compared to Healthy Children

2020 ◽  
Vol 15 ◽  
Author(s):  
Golnaz Vaseghi ◽  
Azadeh Eshraghi ◽  
Nahid Rahimzadeh ◽  
Hasan Amiri ◽  
Mohammadreza Jahed
Keyword(s):  
Urinary Tract ◽  
Acute Pyelonephritis ◽  
Upper Urinary Tract ◽  
Control Group ◽  
Case Group ◽  
Healthy Children ◽  
Tubular Atrophy ◽  
Carnitine Level ◽  
Cross Sectional ◽  
Antioxidant Agent

Aim: This cross sectional case-control study evaluated the serum carnitine level in children with urinary tract infection (UTI). Background: Acute pyelonephritis (APN), is a common bacterial infection of upper urinary tract in children which may also lead to renal damage and tubular atrophy. Activation of inflammatory mediator bedside alterations in the cytokines and generation of reactive oxygen species (ROS) play a striking role in the development of tissue damage after pyelonephritis. L-carnitine as one of the most potent natural antioxidant agent by inhibition of lipid peroxidation may protect cells and tissues from damage. Methods: A total of 30children with UTI (as a case group) and 30 healthy children (as a control group) which matched as age and sex were enrolled in this study. All children were evaluated and compared as age, sex, weight, body mass index (BMI) and serum carnitine level together. Serum carnitine level wasdetermined using serum carnitine ELISA kit. Results: Demographic and clinical data such as age, sex, weight and BMI were not statistically significant between two groups. The serum carnitine levels were significantly lower in case group with UTI than control group. Mean serum carnitine concentration in the case group and in control group was 36.56 ± 9.87 μmol/l and 62.8±21.35 respectively (P = 0.001). Conclusion: According to our study, it could be concluded that low serum L-carnitine level is linked to UTI in children. Therefore, further studies are needed to confirm our results.

scholarly journals ANALISIS PERBEDAAN JUMLAH NEUTROFIL ANTARA ANAK DOWN SYNDROME DAN ANAK SEHAT - Studi Pada SLB-C Widya Bhakti Semarang dan Mi Mirfa’ul Ulum

2017 ◽  
Vol 4 (1) ◽  
pp. 27
Author(s):  
Riezqia Ayu Wulandari ◽  
Sandy Christiono ◽  
Niluh Ringga
Keyword(s):  
Down Syndrome ◽  
Chromosome 21 ◽  
Control Group ◽  
Healthy Children ◽  
Cross Sectional ◽  
Children With Down Syndrome ◽  
Periodontal Infection ◽  
Significant Difference ◽  
The Difference ◽  
Cross Sectional Design

Background: Down syndrome (DS) is a congenital disorder caused by abnormalities of chromosome 21, resulting in migration defect of neutrophils, specifically in GCF as a marker of increasing periodontal infection. This study aimed to analyze the difference in neutrophil numbers between down syndrome and healthy children.Method: This research was an analytic observational with cross sectional design, and divided into two groups. The control group is consisted of healthy children and the other is consisted of down syndrome children. GCF was taken using paper point number 45-50 for 30 seconds, then it smeared into object glass and painted with giemsa staining. Observations was done by light microscopy with 1000 times magnification.Result: The result of studies with p<0.05 was indicating a significant difference of neutrophil numbers between children with down syndrome and the healthy group.Conclusion: This study concluded that there was a difference in neutrophil numbers due to the migration defect of neutrophils in children with down syndrome, that can cause proneness to periodontal infections.

scholarly journals Self-Rated Health and Pain Problems in Mothers of Healthy Children or Children Requiring Outpatient Observation or Hospitalisation: A Pilot Cross-Sectional Study

2021 ◽  
Vol 18 (18) ◽  
pp. 9543
Author(s):  
Anna Aftyka ◽  
Wojciech Rosa ◽  
Marzena Samardakiewicz
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Control Group ◽  
Depression Symptoms ◽  
Healthy Children ◽  
Cross Sectional ◽  
Self Rated Health ◽  
Maximum Pain

A child’s illness or disability is a considerable stressor for the mother and a risk factor for many psychological problems and somatic diseases. The purpose of the study was to (1) assess the prevalence of poor SRH and pain, (2) compare self-rated health and pain, (3) and identify the determinants of SRH and pain in mothers of healthy children and children requiring ambulatory observation or hospitalization. The study covered 234 mothers of both healthy and unhealthy children who required outpatient observation or treatment at an intensive care unit, neonatal intensive care unit, or oncology department. To analyse the variables obtained, the following tools were used: Self-Rated Health, Numerical Rating, Interpersonal Support Evaluation List, Peritraumatic Distress Inventory, Modified Hospital Anxiety and Depression Scale, and Impact of Effects Scale—Revised. The self-assessment of health in mothers of healthy children and those in need of outpatient observation or hospitalization at units with various specialities differed in a statistically significant way. The severity of the average and maximum pain among mothers of healthy children and those with a history of disease differed statistically significantly. Poor SRH co-occurred with severe maximum pain in all of the examined groups. Both in the control group and the group of mothers of children requiring outpatient observation, poor SRH co-occurred with a high level of anxiety. Only in the control group was a correlation found between the severity of the average and maximum pain and the severity of anxiety and depression symptoms.

Association of consanguineous marriages with congenital anomalies

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Maryam Naveed ◽  
Sajeeha Nadeem ◽  
Amber Hassan ◽  
Imrana Tanvir
Keyword(s):  
Congenital Anomalies ◽  
Genetic Disorders ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Cousin Marriage ◽  
Major Health Problem ◽  
Major Health ◽  
Consanguineous Marriages ◽  
Married Individuals

Congenital anomalies are a major health problem all over the world; especially it is important cause ofdeaths and birth defects, chronic illness and disability in infants. The major cause of this isconsanguineous marriages. Generation of cousin marriages have significant association with congenitalanomalies Objective: To find out the association of consanguineous marriages with congenitalanomalies present at the time of birth Methods: A cross sectional study was conducted at District HeadQuarter Hospital, Okara from May to August, 2018. 100 adult individuals aged between 19 to 55 years, withand without cousin marriage of both genders were consecutively enrolled. Participants were assessedthrough pre-tested questionnaire, with prior written informed consent. Unwilling married individuals andindividuals from other hospitals were not selected Results: According to results there was a significantassociation between generation of cousin marriages with congenital anomalies present at the time ofbirth , as p value was 0.002 Conclusions: Study concluded that the generation of cousin marriages hassignificant association with congenital anomalies present at the time of birth and due to cousin marriage59% of the couples had congenital abnormalities in their children and 85% had genetic disorders.

scholarly journals Vitamin D status in pre-school children in rural Nepal

2015 ◽  
Vol 19 (3) ◽  
pp. 470-476 ◽  
Author(s):  
Diana Avagyan ◽  
Sudan Prasad Neupane ◽  
Thomas E Gundersen ◽  
Ahmed A Madar
Keyword(s):  
Vitamin D ◽  
School Children ◽  
Sun Exposure ◽  
Hypovitaminosis D ◽  
Sociodemographic Factors ◽  
Cross Sectional Study ◽  
Healthy Children ◽  
Vitamin D Status ◽  
Cross Sectional ◽  
Rural Nepal

AbstractObjectiveVitamin D plays a major role in Ca and bone metabolism, and its extraskeletal functions are being appraised. Although inadequate vitamin D concentrations have been reported in populations worldwide, too little is known about vitamin D status and its determinants among children in developing countries. We aimed to determine vitamin D status and its determinants in Nepalese children of pre-school age.DesignA community-based, cross-sectional study.SettingRural Nepal at latitude 27·39°N.SubjectsHealthy children (n280) aged 12–60 months, selected randomly from the records of a vitamin A supplementation programme. Blood samples were collected using the dried blood spot technique and analysed for serum 25-hydroxyvitamin D (s-25(OH)D) concentration using liquid chromatography–tandem mass spectrometry. Ca intake and background variables were assessed with a structured questionnaire.ResultsHypovitaminosis D, defined as s-25(OH)D concentration less than 50 nmol/l, was found in 91·1 % of the children. S-25(OH)D concentration was not related to gender, socio-economic indicators, sun exposure or nutritional status. Currently breast-fed children had higher s-25(OH)D concentrations (36·4 (sd13·2) nmol/l) than those who were not (28·6 (sd9·8) nmol/l,P<0·001). Adjustment for sociodemographic factors did not alter the results.ConclusionThere is widespread vitamin D deficiency among pre-school children in a rural area of Nepal. In our sample, sociodemographic factors did not affect the vitamin D status of children, but prolonged breast-feeding was associated with higher s-25(OH)D concentrations. Further research is required to investigate the health consequences of poor vitamin D status for this population.

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