scholarly journals Perbaikan Gejala Neuropati Pada Pemberian Kombinasi Vitamin B Untuk Pasien Neuropati Diabetikum

Author(s):  
Rizaldy Taslim Pinzon ◽  
Rosa De Lima Renita Sanyasi

Neuropati diabetikum (ND) adalah komplikasi utama yang sering muncul pada pasien diabetes mellitus (DM). Penelitian ini bertujuan untuk menilai efektivitas vitamin B kombinasi terhadap gejala klinis ND dan QoL (kualitas hidup/quality of life) pada pasien DM. Metode yang digunakan dalam penelitian ini adalah metode penelitian one group pre and post test design pada pasien DM dengan ND. Setiap subjek mendapatkan kombinasi vitamin B yang terdiri dari: vitamin B1, vitamin B6, dan vitamin B12 dengan dosis masing-masing secara berurutan: 100 mg, 100 mg, 5000 mcg. Gejala klinis ND diukur dengan menggunakan Total Symptom Score (TSS). Angka QoL diukur dengan menggunakan kuesioner SF-8. Penilaian gejala dilakukan sebanyak 5 kali, dari penilaian awal hingga 3 bulan. Ada 104 subjek pada awal penelitian. Tujuh subjek tidak dapat mengikuti penelitian sampai selesai, sehingga tersisa 97 subjek pada akhir penelitian. Ada perbaikan gejala ND, yang meliputi sensasi nyeri tertusuk, sensasi nyeri terbakar, kesemutan, dan rasa kebas/baal, setelah pemberian kombinasi vitamin B. Perubahan tersebut bermakna secara statistik (p<0,0001). Hasil serupa juga tampak pada QoL. Ada perbaikan QoL dari awal penelitian hingga akhir penelitian. Perbedaan tersebut bermakna secara statistik (physical component summary dengan p<0,0001 dan mental component summary dengan p=0,0001). Kombinasi vitamin B efektif untuk memperbaiki gejala klinis dan meningkatkan kualitas hidup pada pasien ND.

2018 ◽  
Vol 11 (1) ◽  
pp. 1
Author(s):  
Ihsan Taufiq

<p><strong><em>Background:</em></strong><em> </em><em>Diabetes Mellitus (DM) causes a decrease in quality of life in all domains. The most often overlooked cause of DM patients is not carrying out physical activity regularly. </em><strong><em>Purpose:</em></strong><em> </em><em>The purpose of this study was to determine the effect of healthy pathways on the quality of life of type 2 D</em><em>M</em><em> patients in the Health Center in Kotabumi North Lampung in 2017.</em><em> </em><strong><em>Methods:</em></strong><em> </em><em>This study used quasi-experimental pre-post test design with a control group. The number of samples consisted of treatment groups and control groups, each group of 22 respondents. The treatment group was the respondents who carried out healthy walks of intervention, then measured the quality of life of patients with type 2 diabetes mellitus, while the control group did not carry out healthy walking activities. Data analysis uses t test dependent. </em><strong><em>Results:</em></strong><em> </em><em>The results showed that there was an effect of healthy pathways on the quality of life of patients with type 2 diabetes mellitus in the health centers in Kotabumi, North Lampung (p = 0.007). <strong>Conclusions</strong></em><strong><em>:</em></strong><em> Healthy paths improve the quality of life for patients with type 2 diabetes, including aspects of physical health, psychological health, social and environmental relations. </em></p><p><strong>Latar Belakang:</strong> Penyakit Diabetes Mellitus (DM) menyebabkan penurunan kualitas hidup disemua domain. Penyebab yang paling sering diabaikan penderita DM adalah tidak melaksanakan aktivitas fisik secara teratur. <strong>Tujuan: </strong>Tujuan penelitian ini untuk mengetahui pengaruh jalan sehat terhadap kualitas hidup penderita DM tipe 2 di Puskesmas wilayah Kotabumi Lampung Utara Tahun 2017. <strong>Metode:</strong> Penelitian ini menggunakan <em>kuasi eksperimen pre post test design </em> dengan kelompok kontrol. Jumlah sampel terdiri atas kelompok perlakuan dan kelompok kontrol masing-masing kelompok 22 responden. Kelompok perlakuan adalah responden yang dilakukan intervensi jalan sehat, kemudian dilakukan pengukuran kualitas hidup penderita DM tipe 2, sedangkan kelompok kontrol tidak melakukan kegiatan jalan sehat. Analisis data menggunakan <em>t </em><em>test dependent</em>. <strong>Hasil:</strong> Hasil penelitian menunjukkan terdapat pengaruh jalan sehat terhadap kualitas hidup penderita DM tipe 2 di Puskesmas wilayah Kotabumi Lampung Utara (p=0,007). <strong>Simpulan:</strong> Jalan sehat meningkatkan kualitas hidup penderita DM tipe 2 meliputi aspek kesehatan fisik, kesehatan psikologis, hubungan sosial dan lingkungan.</p>


2019 ◽  
Vol 5 (1) ◽  
pp. 6
Author(s):  
Rizaldy Taslim Pinzon ◽  
Rosa De Lima Renita Sanyasi

Pendahuluan: Neuropati diabetikum (ND) adalah salah satu bentuk neuropati yang paling umum dijumpai. Terapi yang ada saat ini lebih ditujukan untuk mengatasi gejala. Pemberian kombinasi vitamin B ditujukan bukan hanya untuk mengendalikan gejala, namun memperbaiki fungsi saraf. Penelitian terdahulu tentang vitamin untuk neuropati diabetika masih terbatas dan belum konklusif. Tujuan: Penelitian ini bertujuan untuk menilai efektivitas vitamin B kombinasi terhadap gejala klinis neuropati diabetika dan kualitas hidup (QoL) pada pasien diabetes melitus (DM). Metode: Metode yang digunakan dalam penelitian ini adalah metode penelitian observasional pada pasien DM dengan ND. Setiap subjek memperoleh vitamin B kombinasi yang terdiri dari vitamin B1, vitamin B6, dan vitamin B12 dengan dosis masing-masing secara berurutan 100 mg, 100 mg, dan 5 mg. Gejala klinis ND dinilai dengan menggunakan Total Symptom Score (TSS). QoL dinilai dengan menggunakan kuesioner SF-8. Penilaian dilakukan sebanyak 5 kali, yaitu penilaian awal hingga 3 bulan. Hasil: Total terdapat 104 subjek pada awal penelitian. Tujuh subjek tidak dapat mengikuti penelitian sampai selesai, sehingga tersisa 97 subjek pada akhir penelitian. Terdapat perbaikan berbagai gejala ND, yang meliputi sensasi nyeri tertusuk, sensasi nyeri terbakar, kesemutan, dan rasa kebas/baal, setelah pemberian vitamin B kombinasi. Perubahan tersebut bermakna secara statistik (p < 0,0001). Hal serupa juga tampak pada QoL. Terdapat perbaikan QoL dari awal penelitian hingga akhir penelitian. Perbedaan tersebut bermakna secara statistik (physical component summary dengan p < 0,0001 dan mental component summary dengan p = 0,0001). Kesimpulan: Vitamin B kombinasi efektif untuk memperbaiki gejala klinis dan meningkatkan kualitas hidup pada pasien ND.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
J Funuyet-Salas ◽  
A Martín-Rodríguez ◽  
M A Pérez-San-Gregorio ◽  
M Romero-Gómez

Abstract Background To date, coping strategies have not been studied in patients with nonalcoholic fatty liver disease (NAFLD), despite evidence of their relevance in chronic liver pathology, Type 2 diabetes mellitus (T2DM) and obesity (OB). We therefore analyzed which coping strategies predicted quality of life in diabetic and obese NAFLD patients. Methods Four hundred and ninety-two biopsy-proven NAFLD patients (290 men and 202 women, mean age 54.90±11.74) were evaluated using The Brief COPE, 12-Item Short-Form Health Survey (SF-12) and Chronic Liver Disease Questionnaire-Non-Alcoholic Fatty Liver Disease (CLDQ-NAFLD). A stepwise multiple linear regression analysis was performed on four groups (G1, n = 335, absence of T2DM; G2, n = 157, presence of T2DM; G3, n = 249, absence of OB; and G4, n = 243, presence of OB) to analyze which coping strategies predicted patient quality of life (physical component summary SF-12, mental component summary SF-12, and total CLDQ-NAFLD). Results In both diabetic and obese patients, active coping (T2DM, p = 0.003, β = 0.26; OB, p = 0.000, β = 0.33) and denial (T2DM, p = 0.027, β=-0.19; OB, p = 0.004, β=-0.18) predicted the physical component summary. Denial (T2DM, p = 0.000, β=-0.30; OB, p = 0.001, β=-0.19), positive reframing (T2DM, p = 0.000, β = 0.28; OB, p = 0.000, β = 0.29), self-blame (T2DM, p = 0.000, β=-0.24; OB, p = 0.000, β=-0.26) and self-distraction (T2DM, p = 0.033, β=-0.13; OB, p = 0.023, β=-0.11) predicted the mental component summary. Denial (T2DM, p = 0.000, β=-0.34; OB, p = 0.000, β=-0.31), positive reframing (T2DM, p = 0.000, β = 0.30; OB, p = 0.005, β = 0.15) and self-blame (T2DM, p = 0.000, β=-0.26; OB, p = 0.000, β=-0.28) also predicted the total CLDQ-NAFLD in both groups. Conclusions Active coping and positive reframing predicted better quality of life, while denial, self-blame and self-distraction predicted worse quality of life in diabetic and obese NAFLD patients, suggesting the inclusion of coping strategies in future multidisciplinary NAFLD treatments. Key messages Importance of coping strategies for NAFLD patients: active coping and positive reframing predicted better quality of life, while denial, self-blame and self-distraction predicted worse quality. This study shows the need to design multidisciplinary strategies for managing NAFLD and improving patient quality of life, in which intervention in coping strategies should be a major element.


2021 ◽  
Vol 5 (1) ◽  
pp. 854
Author(s):  
Ellyvina Setya Dhini ◽  
Wibowo Wibowo ◽  
Mamiek Wilastri

ABSTRAKAngka prevalensi Diabetes Mellitus (DM) di Jawa Timur lebih tinggi dibandingkan dengan daerah lain di Indonesia. Hal ini tergambar  di kota Malang  Jawa Timur tepatnya di Kelurahan Kauman yang berdomisili ditengah kota diketahui jumlah penderita DM cukup tinggi sedangkan pengetahuan warganya dalam pemahaman gaya hidup sehat penderita DM (diabetisi) masih kurang. Tujuan dari pengabdian kepada masyarakat (PKM) ini adalah memberikan pengetahuan tentang gaya hidup sehat diabetisi, dengan metode melakukan pelatihan melalui media zoom kepada kelompok PKK Kelurahan Kauman Malang. Dalam pelatihan tersebut juga dilakukan pre dan post test serta pengisian kuisioner menggunakan google form oleh peserta pelatihan. Hasil dari pre dan  post test serta kuisioner dianalisa sehingga diperoleh persentase untuk mengetahui gambaran pemahaman dan kemampuan peserta dalam memberikan informasi dan melaksanakan gaya hidup sehat diabetisi kepada keluarga/ tetangga disekitarnya. Dari hasil pre dan post test diperoleh gambaran terjadinya peningkatan pengetahuan tentang gaya hidup sehat diabetisi dari rata rata 46% menjadi 98,8%. Peserta yang memahami dan menyatakan bahwa gaya hidup sehat diabetisi memungkinkan untuk diterapkan dalam kehidupan sehari hari sebanyak 94%. Seluruh peserta (100%) bersedia menerangkan, menerapkan, melaksanakan dan telah terjadi perubahan gaya hidup sehat diabetisi kepada keluarga dan orang – orang dilingkungan sekitarnya. Hasil dari pelatihan ini memberikan harapan tejadinya perbaikan kualitas hidup diabetisi di Kelurahan Kauman kota Malang. Kata kunci : gaya hidup; diabetes mellitus; kelompok PKK ABSTRACTPrevalence of Diabetes Mellitus (DM) in East Java is higher than other regions in Indonesia. That illustrated in the city of Malang, East Java, precisely in the Kauman Village, which is domiciled in the middle of the city, it is known that number of DM sufferers is quite high, while the knowledge of  citizens in understanding of healthy lifestyle of DM patients) is still lacking.The purpose of this community service (PKM) is to provide knowledge about healthy lifestyles with diabetes, with the method of conducting training through zoom media to the PKK group in Kauman Malang Village. In the training, pre and post tests were also carried out as well as filling out questionnaires using google forms by the trainees to get a picture of the participants' understanding and ability in providing information and implementing a healthy lifestyle with diabetes to their families/neighbors around them. The results of pre and post tests, it was obtained  there was an increase in knowledge about a healthy lifestyle with diabetes from an average of 46% to 98.8%. Participants who understand and state that a healthy lifestyle with diabetes allows it to be applied in daily life as many as 94%. All participants (100%) are willing to explain, implementation and there have been changes to a healthy lifestyle with diabetes to their families and people in the surrounding environment. The results of this training provide hope for an improvement in the quality of life for people with diabetes in Kauman Village, Malang City. Keywords : lifestyle; diabetes mellitus; PKK group


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
M Hurmuz ◽  
S M Jansen-Kosterink ◽  
L van Velsen

Abstract Background Older adults are usually less physically active than younger adults. Physical inactivity can lead to frailty, which can increase the possibility of being admitted in a hospital and, being functional limited. To handle frailty Stranded is developed. Within this platform the user will be shipwrecked and has to build a boat to leave an uninhibited island. The user can leave the island by executing physical exercises and playing cognitive games. The primary aim focussed on differences in quality of life and perceived health status after using Stranded (TRL7). The secondary aim focussed on the usability of and user experience with Stranded. This study was conducted within the FRAIL-project (Eurostars-2 10.824). Methods An observational cohort study with a pre-test/post-test design was carried out. The pre-test measurements were performed before the use of Stranded, and the post-test measurements after using it for four weeks. The study population consisted of older adults, 55 years of age or older and each subject signed an informed consent form. Results One hundred and eleven older adults were included in this study (64.9% female and 35.1% male) and 91 participants started using Stranded. In total, 59 subjects dropped out. Two health variables significantly increased (n = 52), the subjects' perceived health state on a visual analogue scale and the subjects' quality of life viewed from the positive health perspective. Stranded's usability scored an average of 61.3 (SD = 21.6). The average scores on the user experience domains were all between 3.3 and 3.9 on a 7-point scale. The subjects did not have a strong negative or positive opinion about these domains. Conclusions The average quality of life increased slightly. It is hard to find an appropriate population to investigate the effects of these innovations, because of not willing to include too frail older adults for whom participating could be intensive. The usability was perceived as acceptable.


2019 ◽  
Author(s):  
Abraha Gosh Woldemariam ◽  
Haftom Desta Kahsay

Abstract Objective: purpose of this study was to compare the quality of life of people with schizophrenia to healthy controls. Results: the present study demonstrated that respondents with schizophrenia have significantly lower scores in Physical component summary ( U=70.5, z=-8.695, p<..001, r=-.734 ), mental component summary ( U=79.0,z= -8.634 p<.001, r=-.730 ), Physical functioning ( U=310, z-9.553, p<.001, r=-.808 ), Role Physical ( U=419, z=-8.975, p<.001, r=-.759 ), Body pain ( U=1395.5, z=-3.501, p<.001, r=-.296 ), General health ( U=320,z=-7.514, p<.001, r=-.635 ), Vitality ( U=353, z=-7.398, p=.001, r=-.625 ), Social functioning ( U=213.5, z=-9.398, p<.001, r=-.794 ), Role emotion ( U=144.5, z=-985, p<.001, r=-.844 ) and Mental health ( U=178, z=-8.199, p<.001, r=-.693 ) compared with healthy controls. Key words: Quality of life, Schizophrenia, Controls, Case-Control


2020 ◽  
Vol 15 (2) ◽  
pp. 191-199 ◽  
Author(s):  
Gopesh K. Modi ◽  
Ashok K. Yadav ◽  
Arpita Ghosh ◽  
Kajal Kamboj ◽  
Prabhjot Kaur ◽  
...  

Background and objectivesPatient-reported outcomes have gained prominence in the management of chronic noncommunicable diseases. Measurement of health-related quality of life is being increasingly incorporated into medical decision making and health care delivery processes.Design, setting, participants, & measurementsThe Indian Chronic Kidney Disease Study is a prospective cohort of participants with mild to moderate CKD. Baseline health-related quality of life scores, determined by the standardized Kidney Disease Quality of Life 36 item instrument, are presented for the inception cohort (n=2919). Scores are presented on five subscales: mental component summary, physical component summary, burden, effect of kidney disease, and symptom and problems; each is scored 0–100. The associations of socioeconomic and clinical parameters with the five subscale scores and lower quality of life (defined as subscale score <1 SD of the sample mean) were examined. The main socioeconomic factors studied were sex, education, occupation, and income. The key medical factors studied were age, eGFR, diabetes, hypertension, and albuminuria.ResultsThe mean (SD) subscale scores were physical component summary score, 43±9; mental component summary score, 48±10; burden, 61±33; effects, 87±13; and symptoms, 90±20. Among the socioeconomic variables, women, lower education, and lower income were negatively associated with reduced scores across all subscales. For instance, the respective β-coefficients (SD) for association with the physical component summary subscale were −2.6 (−3.4 to −1.8), −1.5 (−2.2 to −0.7), and −1.6 (−2.7 to −0.5). Medical factors had inconsistent or no association with subscale scores. The quality of life scores also displayed regional variations.ConclusionsIn this first of its kind analysis from India, predominantly socioeconomic factors were associated with quality of life scores in patients with CKD.


2017 ◽  
Vol 7 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Srijana Ghimire ◽  
Milan Lopchan

The quality of life (QOL) needs to be regularly assessed in hemodialysis patients. Hemodialysis patients suffer from average quality of life and survival. A descriptive research design was used, 96 respondents who had received haemodialysis treatment after completion of 1 month duration of hemodialysis in two different teaching hospital at Bharatpur, Chitwan. Data was collected by using standard tool Short Form-36 version2 through face to face structure interview schedule. The objective of study is to find out the quality of life (QOL) of haemodialysis patients. Various test such as one sample t-test, ANOVA test, independent t-test, Kruskal-Wallis test and Mann-Whittney U test, Pearson’s correlation was applied. The findings showed that higher proportion of respondents were from 40-59 years (41.0%) and male (62.2%). The mean±SD was 57.45±16.25, 55.72±22.41 and 60.04±11.50 in overall QOL, physical and mental component summary respectively which was slightly above the average. All dimention and sub scale was satistically significant. Younger respondents had statistically significant with overall QOL (p<0.001) and physical component summary (p<0.001). Non diabetics had better in overall QOL (p=0.040) and physical component summary (p=0.033). Level of educational had also positive impact in overall QOL(p=0.010), physical (p=0.006) and mental component summary (p<0.001). Employment status (p=0.020) and sex (p=0.037) was also statistically significant with mental component summary. There was correlation between physical and mental component summary with overall QOL 0.970(p<0.001) and 0.698(p<0.001), and between the physical and mental component summary was 0.502(p<0.001). Below average score were seen in the general health (32.86±25.74) and vitality (41.53±13.98) sub scale. In order to improve quality of life family, physician, nurses and policy makers can use this finding.


2015 ◽  
Vol 37 (2) ◽  
pp. 107
Author(s):  
Bestari J Budiman ◽  
Effy Huriati ◽  
Hafni Bachtiar ◽  
Ade Asyari

AbstrakGejala sumbatan hidung meskipun bukan suatu gejala penyakit yang berat, tetapi dapat menurunkan kualitas hidup dan aktivitas penderita. Salah satu penyebabnya adalah deviasi septum nasi. Pemeriksaan penunjang yang dapat digunakan untuk mendiagnosis dan mengevaluasi gejala sumbatan hidung, diantaranya adalah Nasal Inspiratory Peak Flowmeter (NIPF). Tujuan penelitian ini adalah untuk mengetahui pengaruh septoplasti terhadap sumbatan hidung pada deviasi septum dengan pemeriksaan NIPF. Metode penelitian ini adalah eksperimental studi dengan teknik pre dan post-test design untuk mengetahui gambaran hasil NIPF pada penderita deviasi septum nasi dengan sumbatan hidung. Pengukuran NIPF dilakukan sebelum operasi, minggu ke-2, ke-4 dan ke-6 setelah operasi. Hasil penelitian ini menunjukkan terdapat 11 pasien (93%) dari 12 pasien secara subyektif mengalami perbaikan sumbatan hidung. Terdapat perubahan sumbatan hidung yang bermakna pada minggu ke-4 (p=0,01), dan ke-6 (p=0,01). Kesimpulan penelitian ini adalah septoplasti dapat memperbaiki sumbatan hidung pada deviasi septum nasi.AbstractEven though nasal congestion is not a severe symptom, it can reduce quality of life and patient’s activities. One of the causes of nasal congestion is septal deviation. Diagnostic test that could be used to evaluate nasal congestion is Nasal Inspiratory Peak Flowmeter (NIPF). The objective of this study was to measure the effect of septoplasty to nasal congestion caused by septal deviation with NIPF examination. This research was experimental study by pre and post-test design to evaluate NIPF of patients with nasal congestion due to septal deviation. NIPF was measured before operation surgery, second week, fourth week and sixth week after surgery. The result showed that there were 11 patients (93%) of 12 patients with decreased of nasal congestion subjectively. There were significant decrease of nasal congestion at fourth week (p=0.01) and sixth week (p=0.01). The conclusion of this study is septoplasty can reduce nasal congestion on septal deviation.


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