scholarly journals CONDITION OF MORBIDITY AND QUESTIONS OF EPIDEMIOLOGY OF LEISHMANIASIS IN THE SOGDIAN REGION OF TAJIKISTAN

2019 ◽  
pp. 616-621
Author(s):  
Tadzhibaev ◽  
Murtazoev ◽  
Pulotov

Since 2003, visceral, and since 2009, skin leishmaniasis has been registered in the Sughd region and remains a significant problem for health care, especially the VL. The main risk group is children of 0–5 years old, whose immune system cannot with-stand leishmania. With late diagnosis and treatment can be fatal. The survey results indicate the epidemic activity of the synanthropic focal point of the VL. According to the epidemiological studies, it can be assumed that the foci of leishmaniasis in the Sogd region are anthropurgic. In many localities, Ph. sergenti is the dominant type of carrier, which is an anthroponotic carrier, and the presence of Ph. papatasi, the main carrier of zoonotic CL, indicates the pathogen circulation in the region.In order to combat leishmaniasis, it is recommended to conduct in the foci an early diagnosis and treatment of patients, active identification, treatment and shooting of sick dogs, extermination of rodents, treatment of residential and other household premises with long-lasting insecticides, sanitary improvement of premises for live-stock from manure, elimination of landfills (especially those containing food and agricultural waste) in the vicinity of localities, the use of impregnated bed curtains and sanitary educational work among the population.

2020 ◽  
pp. 101-108
Author(s):  
A. Ya. Trotskovsky ◽  
O. V. Sitnikova ◽  
I. V. Suponina

The article reveals the features of the adaptive behavior of young people and elderly citizens during the recession of the economy of the Altai Territory. As the information base of the study, the data of state statistics were used, including sample survey results. The specificity of the article lies in an attempt to make a comparative analysis of the economic behavior of citizens included in the “risk group” in the labor market, under the conditions of a slowdown in the economy of a typical agro-industrial region. The characteristic features of the development of the Altai Territory at the recession stage (2013-2016) are revealed. The essence of the changes lies in the formation of a qualitatively different economic situation, due to a noticeable inhibition of the growth of a number of basic indicators of the socio-economic development of the region. The key features of the development of the Altai Territory during the years of recession are noted, consisting in a relatively stable socio-economic situation in general, and the preservation of the basic characteristics of the labor market, in particular. It was found that the economic slowdown affected mainly the indicators of the level of employment and the growth of unemployment; the level of participation in the labor force has not changed. The gender features of the level of participation in the workforce of young people and elderly citizens are revealed. The specifics of employment of young people and elderly citizens during the recession of the economy in the region are disclosed. It is noted that in comparison with Russia, the problem of unemployment in the considered groups of the population is expressed differently: less acute for young people and more acute for elderly citizens.


2020 ◽  
Vol 2 (3(September-December)) ◽  
pp. e622020
Author(s):  
Alick Durão Moreira ◽  
Antonio Bellas ◽  
Marcelo Sampaio Poousa ◽  
Rafaeldos Santos Mitraud Mitraud ◽  
Tatiana Protzenko

Introduction:Congenital Dermal Sinuses (CDS) are rare closed dysraphisms that can present throughout the extent of the neuroaxis. They occur due to a failure of the disjunction of the neuroectoderm and cutaneous ectoderm in a focal point during 3-4 week of embryogenic development. The prevalence of CDS of all types has been estimated to be 1 in 2,500 live births, most commonly localized in the lumbar region. More than half of the cases are associated with dermoid or epidermoid tumors. Clinical presentation of CDS usually consists in cutaneous stigmas like dimples, which has the potential to be diagnosed at birth. However, the majority of patients are diagnosed older and after complications such as meningitis, abscess, osteomyelitis, rupture of an associated epi/dermoid cyst. Once suspected the patient should be submitted to an image study with CT scan and/or MRI, and surgical consultation. Complete exeresis is the definitive treatment. Case report: we present 3 cases of CDS, including an extremely rare case of frontonasal location, to illustrate the extent of the disease and the importance of early diagnosis and treatment. All of the 3 cases presented with complications, requiring surgical treatment and long term antibiotic therapy. Conclusion: Although well reported in the literature, CDS are usually diagnosed after complications. The knowledge of clinical presentation, early diagnosis and treatment are essential to prevent its life threatening complications. 


Author(s):  
Dahliani Reynolds ◽  
Loren Byrne ◽  
Jennifer Campbell ◽  
Becky Spritz

First-Year Experience (FYE) programs have become a focal point for efforts to transition and retain all students, as numerous studies suggest that such initiatives deepen students’ academic preparation for college and support their emotional investments in the campus community. Using quantitative and qualitative data gathered from 842 students in 54 courses during Fall 2013 and 2014, this article considers the comparative merits of Living Learning Communities (LLC), “habits of mind” First-Semester Core (FSC) courses, a hybrid-model (LLC-FSC) initiative, and non-FYE courses by considering students’ perception of their academic gains and social engagement. Survey results indicate that students perceive very different benefits across the various FYE models, especially when the FYE is housed in disciplinary rather than general education courses. The comparisons suggest the need for an intentional, goals-oriented approach to FYE programs, as a “one-size fits all” approach may not result in both academic growth and community engagement for students. For institutions with limited faculty and curricular resources, the choice of which type of FYE model to adopt is particularly important. 


2021 ◽  
Author(s):  
Tian Wang ◽  
Lin-li Zhang ◽  
Qing-hui Feng ◽  
Meng-ling Wang ◽  
Yu-Chun Fan ◽  
...  

Abstract Background Many recent studies have reported the role of WGCNA in liver cancer, and screened out modules related to the clinical characteristics of liver cancer. The prognostic role of modular genes provides a reference for the treatment of liver cancer and the study of survival time extension. MethodsUse edgeR to screen differentially expressed genes, and use weighted gene co-expression network analysis (WGCNA) method to divide differential genes into modules; combined with clinical data, select gene modules that are highly related to clinical information to construct a prognostic model. Use univariate Cox and multivariate Cox regression analysis to predict the value of prognosis. The Kaplan-Meier method and ROC curves were used to evaluate the value of features of predicting prognosis.ResultsIn the co-expression analysis of liver cancer, the two gene modules darkrey and navajowhite2 was highly correlated with the TNM stag of liver cancer. In addition, they were related to the reduction process and the activation of specific DNA-binding transcription factors. Constructing a risk ratio model with these two modules shows that the overall survival time of patients in the high-risk group is lower than that of the low-risk group. In the module, ABLIM2, RP11-109J4.1, TXNRD1, C9orf106, LINC00677, CYP11B2, AC005550.3 and MIR3945HG belong to the Hub gene, and can also be used as independent prognostic factors, which may become potential biomarkers for the diagnosis and treatment of liver cancer. Conclusion This studies identified and screened the prognostic genes RP11-109J4.1, TXNRD1, C9orf106, LINC00677, CYP11B2, AC005550.3 and MIR3945HG related to the progression of liver cancer, which can provide a reference form the diagnosis and treatment of liver cancer.


2014 ◽  
Vol 18 (5) ◽  
pp. 14-19 ◽  
Author(s):  
T.S. IERMAKOVA

Aim: to study the experience of the structure and system of training of future teachers in Polish schools. Material: content analysis of domestic and foreign authors. Used data from the survey of students of Polish universities. Also were used survey results through polish service ANKIETKA. For comparison, a questionnaire survey 35 students of the Faculty of Physical Education (future teachers of physical training) and 30 students - the future teachers of elementary school of Ukrainian university. Results: the study of Polish teachers consider health culture of a person as the ability to assess individual and community health needs using in everyday life hygiene and health regulations. There have been some differences among Ukrainian and Polish students in their health and health culture. Among the respondents, Polish students - the future teachers of physical culture, is dominated motives such as the improvement of the physical condition, strengthen self-esteem, as well as improved health. Polish students from other disciplines believe that the most important motive for the adoption of physical activity is a concern for the physical well-being and mental health. The majority of Ukrainian students (future teachers of physical culture) believe an important part of building health culture of their direct participation in various sports clubs, as well as the ability to organize physical culture, sports and educational work with students outside the classroom. Ukrainian students (other specialty) noted the need to improve health, enhance knowledge in specific subjects humanities and promoting healthy lifestyles. Conclusions: It is recommended to use the experience of preparing students of Polish schools in modern Ukrainian higher education.


Author(s):  
Milan Stanojevic

ABSTRACT Understanding the relation between fetal and infant behavior and developmental processes of the brain in different periods of gestation may make achievable the distinction between normal and abnormal brain development as well as the early diagnosis of various structural or functional abnormalities. As the development of the brain is unique and continuing process throughout the gestation and after birth, it is expected that there is also continuity of fetal and neonatal behavior, which is the best functional indicator of developmental processes of the brain. The aim is to present continuity of the general and other movements from prenatal to postnatal life in fetuses and newborns from low- and high-risk pregnancies. Epidemiological studies revealed that many neurologically impaired infants belong to low-risk population, which means that they seemed to be developmentally normal as fetuses and as infants, while later in childhood neurological disability was diagnosed. Dyskinetic cerebral palsy (CP) is the dominant type of CP found in term-born, appropriate-for-gestational-age children with severe impairments who have frequently experienced adverse perinatal events. As neuroprotective methods of treatment are available for some infants, simple screening methods could be helpful to detect impaired fetuses early enough in order to avoid developmental catastrophe. It has been clear from postnatal assessment of Prechtl's neonatal general movements (GMs) that it is a better predictor of neurodevelopmental disability than neurological examination. Introduction of two-dimensional (2D) and four-dimensional (4D) ultrasound enabled introduction of GMs assessment to the prenatal period. Kurjak et al conducted a study by 4D ultrasound and confirmed earlier findings made by 2D ultrasonography, that there is behavioral pattern continuity from prenatal to postnatal life. New antenatal neurological screening test has been introduced by Kurjak et al (KANET), which was postnatally followed by postnatal neurological screening assessment according to Amiel-Tison (ATNAT). Although many fetal behavioral studies have been conducted in low- and high-risk pregnancies and KANET has been recently standardized, it is still questionable whether the assessment of continuity from fetal to neonatal behavior could improve ability for early detection of brain pathology.


2019 ◽  
Vol 72 (5) ◽  
pp. 950-955
Author(s):  
Pavlo I. Tkachenko ◽  
Ivan I. Starchenko ◽  
Serhii O. Bilokon ◽  
Oleksii K. Prylutskyi ◽  
Nataliia M. Lokhmatova ◽  
...  

Introduction: The part of purulent inflammatory processes (IP) of the maxillofacial area (MFA) as a result of insect bites are increased. The aim: To attract attention of the medical community to the problem of the complexity of the diagnosis and treatment of these dermatogenic forms of IP MFA. Materials and methods: The work is based on the results of 5 year observations of 42 patients with acute IP MFA arising after insect bites, their comprehensive examination and treatment. Conclusions:1. IP of MFA, arising as a result of insect bites, is a very urgent problem of pediatric surgical dentistry and require an individual approach in the diagnosis and treatment of patients. 2. A large role in preventing the occurrence of these nosological forms is given to medical workers, a sufficient organization level of sanitary and educational work, and thetreatment of such cases becomes a common task of doctors of different profiles. However, much depends on the parents, their level of responsibility and competency, ensuringof timely treatment and provision of qualified medical care to children, preventing the development of severe complications. 3. The issues related to the etiopathogenesis of this pathology require profound scientific research.


2004 ◽  
Vol 50 (2) ◽  
pp. 47-53
Author(s):  
V. V. Fadeev

The relevance of the problem of hypothyroidism in the clinical practice of doctors of all specialties is not necessary. Hypothyroidism is one of the most common diseases of the endocrine system. According to some epidemiological studies, in certain population groups the prevalence of subclinical hypothyroidism reaches 10-12% [16]. In the last decade, a large number of works on the problem of hypothyroidism have appeared, which have transformed our views on the entire pathology of the thyroid gland (thyroid gland). This is primarily due to the introduction of modern thyroid hormone preparations into clinical practice.


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