Skin Moisture and MoisturizersCONTENTSOverviewWhat causes dry skin?Significance of skin moisture: characteristics of dry skinThe beneficial effects of moisturizersNatural factors that prevent skin dryness· Wetting the skinWetting the skinMoisturizers: occlusives and humectantsHow to select a moisturizerGuidelines for use of moisturizersThe difference between moisturizers for the face and those for the bodyMoisturizers for the handsSummary

Author(s):  
Avi Shai ◽  
Howard I. Maibach ◽  
Robert Baran
Author(s):  
Su-In Park, Soo Hyeon Heo, Jinseo Lee, Hoon Cha, Moon Sam Shin

In this study, Arg 4 (R4) was conjugated with Pal-GHK to get palmitoyl heptapeptide, Pal-GHK‐R4 and wrinkle improvement clinical trials of cosmetics containing Pal-GHK‐R4 were conducted. As a result of total 21 subjects used the test products 4 weeks use on the face area; 1) measurement results of crow’s feet after 2 and 4 weeks of test products use, analysis value of crow’s feet statistically significantly decreased after 2 and 4 weeks of test products use compared to before use of products (p<0.05); 2) measurement results of skin moisturization after 2 and 4 weeks test products use, measured value of skin moisture content statistically significantly increased after 2 and 4 weeks use compared to before use of products (p<0.05); 3) measurement results of TEWL after 2 and 4 weeks use, measured value of TEWL statistically significantly decreased after 2 and 4 weeks use compared to before use of product(p<0.05); 4) there was no skin adverse event reported after using the products during the study period. Therefore, the test products containing both wrinkle improving and skin penetrating peptides, Pal-GHK‐R4 are considered to have beneficial effects on improvement of skin wrinkle, moisturization, transepidermal water loss(TEWL) after 2 and 4 weeks use of test product.


2019 ◽  
Vol 7 (3) ◽  
pp. 138
Author(s):  
Swaidatul Masluhiya AF ◽  
Hasminar Rachman Fidiastuti

This study aimed to determine the effect of using natural masks to moisturize dry skin. This natural mask was made of ingredients that are safe to use and based on special formulations which include; bengkoang powder (2 grams), chocolate powder (1 gram), black cumin oil (0.6 ml), and honey (5 ml). This formulation was made so that the resultied mask formed paste stucture that can be directly applied. Masks were given to ten probandal women who have dry skin types and are 30-40 years old. Masks were used twice / week for six weeks (12 times usage). The instrument used to measure the moisture level of facial skin was a skin analyzer (HL-611) by directly attaching it to the face area and the results can be seen after 4-5 seconds. The data were analysed using ANOVA test 95% confidence interval and significance test using SPSS 15 for windows. The results showed that skin moisture values increased around 3.9% within 6 weeks of use, with a 0.8% increase at week 2, at week 4 there was an increase of 1.65% and at week 6 there was an increase in skin moisture by 1.4%. The moisture value of the skin on the face area (forehead, nose, chin, cheeks) showed no significant difference with almost the same value of humidity. It is recommended for dry skin types to use a face mask that contains oil as a skin lubricant and to protect water evaporation from the skin. It is necessary to do further testing on this natural mask so that safety on the skin can be guaranteed. It needs to be done so that the final product obtained meets the face mask safety quality standards set by the government. Keywords: Bengkuang; cocoa; black cumin; honey; natural mask.


2020 ◽  
Vol 2 (2) ◽  
pp. 63-68
Author(s):  
Chandra Pranata ◽  
Novidawati Boru Situmorang ◽  
Romauli Anna Teresia Marbun

ABSTRACT     Skin is an essential and vital organ and a reflection of health. Natural antioxidants such as flavonoids, polyphenols and Sapponin are believed to increase moisture on the skin. This ability is the main reason for using Torch Ginger flower extract which is formulated into a form of facial mask in the form of clay facial mask. Objective: To formulate facial moisturizing mask preparations using the extract of Torch Ginger(Etlingera elatior). This study used the Torch Ginger Flower extract facial moisturizing mask formulation method with a concentration of 0 (Blank), 5% and 10%. Evaluation of mask preparations included homogeneity, stability of dosage at temperatures of 80C and 250C, Organoleptic test and pH of preparations. Measurements of skin moisture activity were measured using alar Skin Analyzer which was tested on the face surface 3cm wide. The results showed that the preparation was stable in terms of odor, color and was at a pH of 4.2-6.3 using observations of litmus discoloration. Effectiveness of facial skin moisture with 10% Torch Ginger extract concentration is more effective to produce results at a concentration of 5% and blank. Conclusion: Torch Ginger flower extract can be formulated into preparations of face masks with various concentrations and has the effect of moisturizing the skin and brightening the complexion. Keywords: Torch Ginger Flower Extract, Facial Mask, Clay Facial Mask, Facial Skin Moisture


2018 ◽  
Vol 62 (2) ◽  
Author(s):  
Carlos Kornhauser ◽  
Gloria Barbosa-Sabanero ◽  
Noemí Gutierrez-Romero ◽  
Myrna Sabanero ◽  
Elva L. Perez-Luque ◽  
...  

The beneficial effects of a short period of Telmisartan administration were successfully assessed trough pentosidine urinary levels (uPen) and urinary podocyte excretion (UPE), in type 2 diabetes mellitus (DM2) patients. Patients with podocyturia received Telmisartan treatment (80 mg/day) for two months.  uPen were quantified pre and post treatment using HPLC with fluorimetric detection and in-lab synthesized standard. Immunofluorescence method for podocalyxin was used to evaluate urinary excretion of podocytes. uPen and UPE significantly decrease after treatment (p&lt;0.01255 and p&lt;0.005 respectively), as well as serum total cholesterol and LDL levels (p&lt;0.001). These results suggest that podocyte protection by Telmisartan even in the face of deficient metabolic control could be an important matter in the prevention and progression of diabetic nephropathy. This study also strengthens evidence of the promising role of pentosidine as prognostic and diagnostic markers in diabetic nephropathy


2019 ◽  
Author(s):  
Assaf Oshri

Resilience refers to the ability of individuals to thrive in the face of adversity. Extant research shows that resilience is a process that emerges amidst a constellation of risk and protective factors that dynamically transact with each other at multiple levels of analyses. To date, the lion’s share of research on resilience in psychological science has shown risk and protective factors to either impede or support resilience, respectively. Some research is beginning to suggest that resilience develops in response to adversity. However, scarce conceptual frameworks exist to examine the beneficial effects of adversity on resilience. Drawing on the work of various disciplines, I propose that the study of resilience in developmental and psychological sciences can benefit from considering how biomedical disciplines identify the types and dose of adversity that strengthen or impede resilience. Specifically, I discuss how dose-response curvilinear patterns lead to an inoculation effect in the context of specific, circumscribed environmental toxicity, a process that leads to hormesis in the field of toxicology. Thus, the main goal of the paper is to propose that testing for hormesis will contribute to an empirically testable inoculation model of resilience in developmental science.


2021 ◽  
Vol 27 (6) ◽  
pp. 1498-1505
Author(s):  
Eun-Hee Yang ◽  
Yun-Kyoung Oh

This study aimed to comparatively analyze changes in facial size and skin condition after sugar stick fascia therapy and manual technique. Selecting 11 people for sugar stick fascia therapy and 11 people for manual technique, their facial size and skin condition were measured three times before care, after four-times of care, and after eight-times of care. The results were evaluated through survey after experiment. First, regarding the differences in each period and group, the sizes of section A and B were more significantly reduced after sugar stick fascia therapy rather than manual technique, which showed the face downsizing effect (p<.05). Second, regarding the differences in each period, the sugar stick fascia therapy significantly increased moisture and elasticity. Regarding the differences in each group, the moisture was more significantly increased after eight times of sugar stick fascia therapy than manual technique (p<.05). In the evaluation of results, the face downsizing effect and overall satisfaction were highly shown (p<.01). The sugar stick fascia therapy showed great effects on downsizing the cheeks with lots of muscles, and also showed the remarkable increase in moisture. Thus, the sugar stick fascia therapy could be suggested as an alternative care that could meet the desire for beauty, by utilizing it as a face downsizing program without side effects and a skin care program for dry skin.


PEDIATRICS ◽  
1968 ◽  
Vol 42 (2) ◽  
pp. 302-302
Author(s):  
T. E. C.

Prior to a few decades ago, most physicians who cared for infants looked on teething as the cause of many serious pediatric complaints. For example, Harrison in 18621 offers this advice to a young practitioner: But it is especially in reference to affections of the head that the condition of the gums becomes a source of solicitude. During dentition any twitchings in the face, or curious starings of the eyes, are full of meaning, and should never be suffered to pass over without due attention to the teeth. I think all well educated medical men, in this country, are advocates for lancing the gums, though I believe it is very seldom done on the Continent. Mothers, however, not unfrequently object; they think it a pity to hurt the little darling, and they would rather wait awhile and leave matters to nature. Some have an idea that the teeth will be more difficult to cut after the gums are lanced, if the teeth do not immediately protrude. Kennedy, another respected nineteenth century practitioner, who wrote extensively about the management of children in health and disease tells us that: Teething, when difficult, is apt to induce derangement of the vital functions, especially those of the alimentary and nervous systems. Acidity of the stomach with occasional vomiting; quick pulses, hot dry skin, and unnatural dejections, with swelling of the belly and emaciation, require being corrected by the remedies advised for moderating or removing the fevers of infants. . . . Little reasons is afforded by experience, for regarding local applications to the gums as having ever contributed to the relief of painful dentition:-pure air, frequent change of dress, tepid or cool sponging of the body and spine, with regularity of the bowels and salutary nourishment prove far surer instruments of obtaining a favourable result.


Cosmetics ◽  
2021 ◽  
Vol 8 (4) ◽  
pp. 93
Author(s):  
Ana Barrionuevo-Gonzalez ◽  
Sonja Trapp ◽  
Raffaella de Salvo ◽  
Marina Reitmann ◽  
Eva Cassar ◽  
...  

Three novel face creams containing dexpanthenol with different lipid contents were developed for dry skin sufferers: a day face cream (DFC), a day face cream with sun protection (DFC-SPF), and a night face cream (NFC). Three identically designed studies (N = 42–44 each) were conducted with healthy adults of three ethnicities (African, Asian, Caucasian) with dry/sensitive skin. Effects on stratum corneum (SC) hydration, SC lipid content, and skin elasticity were quantified by established noninvasive methods during the 4-week studies. After single and repeated once-daily applications of the face creams, facial hydration significantly increased from baseline. On day 28, the mean increments in skin hydration amounted to 27%, 26%, and 27% (p < 0.0001 each) for DFC, DFC-SPF, and NFC, respectively. Favorable effects of DFC, DFC-SPF, and NFC on facial moisturization were observed in all three ethnic groups. The enhancements in SC hydration were not paralleled by improvements in skin elasticity parameters but lipid analyses showed significant increases in SC cholesterol, SC free fatty acid, and/or SC ceramide levels. All three face creams were well tolerated and achieved a high product satisfaction and acceptability by study participants. Our findings support the once-daily use of the face creams in adults of different ethnicities with dry and sensitive skin.


2013 ◽  
Vol 2013 ◽  
pp. 1-16 ◽  
Author(s):  
Ranjita Sengupta ◽  
Eric Altermann ◽  
Rachel C. Anderson ◽  
Warren C. McNabb ◽  
Paul J. Moughan ◽  
...  

Lactobacillusspecies can exert health promoting effects in the gastrointestinal tract (GIT) through many mechanisms, which include pathogen inhibition, maintenance of microbial balance, immunomodulation, and enhancement of the epithelial barrier function. Different species of the genusLactobacilluscan evoke different responses in the host, and not all strains of the same species can be considered beneficial. Strain variations may be related to diversity of the cell surface architecture of lactobacilli and the bacteria's ability to express certain surface components or secrete specific compounds in response to the host environment. Lactobacilli are known to modify their surface structures in response to stress factors such as bile and low pH, and these adaptations may help their survival in the face of harsh environmental conditions encountered in the GIT. In recent years, multiple cell surface-associated molecules have been implicated in the adherence of lactobacilli to the GIT lining, immunomodulation, and protective effects on intestinal epithelial barrier function. Identification of the relevant bacterial ligands and their host receptors is imperative for a better understanding of the mechanisms through which lactobacilli exert their beneficial effects on human health.


2000 ◽  
Vol 27 (3) ◽  
pp. 553-562 ◽  
Author(s):  
Perry Adebar

Results are presented from 23 shear tests on 1-m deep specimens made of low-strength concrete and tested with shear span-to-effective depth ratios between 1.4 and 2.4 to obtain information that is relevant to the one-way shear strength of footings. Based on these results and other test results from the literature, an amendment is proposed to the 1994 Canadian concrete code one-way shear strength provisions for members without stirrups. In order to account for the beneficial effects of strut-action in deep members such as footings, it is proposed that the reduction in shear strength due to size not be applied to sections located less than 2d from the face of a support or concentrated load when the applied shear introduces compression into the member. The strut-and-tie provisions in the Canadian code, which has stress limits to prevent concrete compression failures, normally should be used to design deep members, but should not be used to design members without minimum stirrups. The proposed revision eliminates the unnecessary increase in footing depths that is needed to meet the one-way shear strength requirements of the 1994 Canadian concrete code.Key words: building codes, footings, reinforced concrete, shear strength, structural design, tests.


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