scholarly journals Associative learning shapes visual discrimination – a web-based study

2021 ◽  
Author(s):  
Yannik Stegmann ◽  
Marta Andreatta ◽  
Paul Pauli ◽  
Matthias J Wieser
Keyword(s):  
Associative Learning ◽  
Visual Discrimination ◽  
Vital Role ◽  
Continuous Measure ◽  
Threat Detection ◽  
Aversive Learning ◽  
Web Based ◽  
Attentional Deployment ◽  
The Us ◽  
The Impact

Threat detection plays a vital role in adapting behavior to changing environments. A fundamental function to improve threat detection is by learning to differentiate be-tween stimuli predicting danger and safety. Accordingly, aversive learning should lead to enhanced sensory discrimination of danger and safety cues. However, studies inves-tigating the psychophysics of visual and auditory perception after aversive learning show divergent findings, and both enhanced and impaired discrimination after aversive learning have been reported. Therefore, the aim of this web-based study is to examine the impact of aversive learning on a continuous measure of visual discrimination. To this end, n = 205 participants underwent a differential fear conditioning paradigm be-fore and after completing a visual discrimination task using differently oriented grating stimuli. Participants saw either unpleasant or neutral pictures as unconditioned stimuli (US). Results demonstrated sharpened visual discrimination for the US-associated stim-ulus (CS+), but not for the unpaired conditioned stimuli (CS-). Importantly, this finding was irrespective of the US’s valence. These findings suggest that associative learning results in increased stimulus salience, which facilitates perceptual discrimination in or-der to prioritize attentional deployment.

scholarly journals Associative learning shapes visual discrimination in a web-based classical conditioning task

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yannik Stegmann ◽  
Marta Andreatta ◽  
Paul Pauli ◽  
Matthias J. Wieser
Keyword(s):  
Associative Learning ◽  
Visual Discrimination ◽  
Vital Role ◽  
Continuous Measure ◽  
Threat Detection ◽  
Aversive Learning ◽  
Web Based ◽  
Attentional Deployment ◽  
Before And After ◽  
The Impact

AbstractThreat detection plays a vital role in adapting behavior to changing environments. A fundamental function to improve threat detection is learning to differentiate between stimuli predicting danger and safety. Accordingly, aversive learning should lead to enhanced sensory discrimination of danger and safety cues. However, studies investigating the psychophysics of visual and auditory perception after aversive learning show divergent findings, and both enhanced and impaired discrimination after aversive learning have been reported. Therefore, the aim of this web-based study is to examine the impact of aversive learning on a continuous measure of visual discrimination. To this end, 205 participants underwent a differential fear conditioning paradigm before and after completing a visual discrimination task using differently oriented grating stimuli. Participants saw either unpleasant or neutral pictures as unconditioned stimuli (US). Results demonstrated sharpened visual discrimination for the US-associated stimulus (CS+), but not for the unpaired conditioned stimuli (CS−). Importantly, this finding was irrespective of the US’s valence. These findings suggest that associative learning results in increased stimulus salience, which facilitates perceptual discrimination in order to prioritize attentional deployment.

scholarly journals RECRUITMENT INTO THE ALZHEIMER PREVENTION TRIALS (APT) WEBSTUDY FOR A TRIAL-READY COHORT FOR PRECLINICAL AND PRODROMAL ALZHEIMER’S DISEASE (TRCPAD)

2020 ◽  
pp. 1-7
Author(s):  
S. Walter ◽  
T.B. Clanton ◽  
O.G. Langford ◽  
M.S. Rafii ◽  
E.J. Shaffer ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Effective Means ◽  
Web Based ◽  
The Us ◽  
Study Team ◽  
Prodromal Alzheimer’S Disease ◽  
Prevention Trials ◽  
Study Participants ◽  
The Impact

BACKGROUND: The Alzheimer Prevention Trials (APT) Webstudy is the first stage in establishing a Trial-ready Cohort for Preclinical and Prodromal Alzheimer’s disease (TRC-PAD). This paper describes recruitment approaches for the APT Webstudy. Objectives: To remotely enroll a cohort of individuals into a web-based longitudinal observational study. Participants are followed quarterly with brief cognitive and functional assessments, and referred to Sites for in-clinic testing and biomarker confirmation prior to enrolling in the Trial-ready Cohort (TRC). Design: Participants are referred to the APT Webstudy from existing registries of individuals interested in brain health and Alzheimer’s disease research, as well as through central and site recruitment efforts. The study team utilizes Urchin Tracking Modules (UTM) codes to better understand the impact of electronic recruitment methods. Setting: A remotely enrolled online study. Participants: Volunteers who are at least 50 years old and interested in Alzheimer’s research. Measurements: Demographics and recruitment source of participant where measured by UTM. Results: 30,650 participants consented to the APT Webstudy as of April 2020, with 69.7% resulting from referrals from online registries. Emails sent by the registry to participants were the most effective means of recruitment. Participants are distributed across the US, and the demographics of the APT Webstudy reflect the referral registries, with 73.1% female, 85.0% highly educated, and 92.5% Caucasian. Conclusions: We have demonstrated the feasibility of enrolling a remote web-based study utilizing existing registries as a primary referral source. The next priority of the study team is to engage in recruitment initiatives that will improve the diversity of the cohort, towards the goal of clinical trials that better represent the US population.

Frequent mask-wearing during the COVID-19 pandemic and acne: an infodemiology study from Google research trends (Preprint)

2021 ◽  
Author(s):  
Samir Salah ◽  
Ann'Laure Demessant-Flavigny ◽  
Delphine Kerob
Keyword(s):  
Census Bureau ◽  
Web Based ◽  
Related Information ◽  
Maximum Value ◽  
The Us ◽  
Exposure Variable ◽  
Health Related ◽  
Us Census ◽  
The Impact ◽  
Calibration Control

BACKGROUND Researchers have been increasingly using the internet as a major source of health-related information and infodemiological methods have provided new approaches for studying the impact of coronavirus disease (COVID-19). OBJECTIVE To verify whether frequent mask-wearing during the COVID-19 pandemic was associated with an increase in acne search popularity. METHODS Data for mask-wearing were obtained from a NYT survey, with 250,000 responses between July 2 and 14, 2020, and from Google COVID-19 symptoms dataset for weekly acne and anxiety search popularity. All data in the study were presented in relation to US county levels. Each county was classified in the frequent mask-wearing group if the proportion of frequent users was above the third quartile. To make search trends comparable from one week to another and from one county to another, search trends were normalized on a relative 100-point scale, with the maximum value corresponding to the highest search popularity for a particular term in a specific week and a specific county. Other sources of data included the US census bureau datasets. Acne search popularity outcome was analyzed using a logistic regression, with COVID-19 incidence, metropolitan status of the county and anxiety search popularity as covariates, and mask-wearing status as the exposure variable. 2019 data, no mask-wearing, was used as a calibration control for acne search weight. RESULTS The final dataset consisted of 2893 counties with complete cases. Frequent mask-wearing was associated with an important increase in acne search popularity (OR=1.69; 95% CI (1.30-2.21); P<.001). A high relative incidence of COVID-19 was associated with an even greater acne search popularity (OR=8.42; 95% CI (6.48-10.96); P<.001). CONCLUSIONS Despite various biases, the use of infodemiology will keep increasing. Observational statistical methods need to be adapted to manage the large amounts of bias concerning web-based information more efficiently.

scholarly journals EXPORT OF SERVICES: IS DATA LOCALIZATION A BARRIER?

2020 ◽  
pp. 22-32
Author(s):  
A. A. Koval ◽  
A. D. Levashenko
Keyword(s):  
Personal Data ◽  
Vital Role ◽  
Cross Border ◽  
Digital Services ◽  
Foreign Countries ◽  
Data Flows ◽  
The Us ◽  
The Cross ◽  
The Impact ◽  
The Eu

The export of services is not related to the physical movement of goods across the border but is directly dependent on the cross-border movement of data. Cross-border data flows play a vital role in the cross-border provision of digital services. The international community pays particular attention to issues regarding the application of data localization policies. Indeed, this requirement significantly affects global trade in services. The data localization policy provides, according to the WTO, limiting the ability of companies to transfer data about internal users to foreign countries. Developing countries (Russia, China, etc.) involve the application of the localization requirement, i.e., first records in the country, personal data of citizens, while the EU and the US consider the total need of data localization as a barrier to international trade. The article assesses the impact of data regulation requirements on the export and import of digital services.

scholarly journals Observational vignette study to examine patient and healthcare provider perceived impact of asthma-related exacerbations in the US

2019 ◽  
Vol 14 ◽  
Author(s):  
Phaedra T. Johnson ◽  
Christopher F. Bell ◽  
John White ◽  
Breanna Essoi ◽  
Linda Nelsen ◽  
...  
Keyword(s):  
Financial Burden ◽  
Healthcare Providers ◽  
Self Care ◽  
Web Based ◽  
The Us ◽  
Household Costs ◽  
Patient Responses ◽  
Care Problems ◽  
Anxiety Depression ◽  
The Impact

Background: Little is known about how patients and healthcare providers (HCPs) perceive the impact of asthmarelated exacerbations. This study examined the impact of asthma-related exacerbations on patients’ lives from these different perspectives. Methods: Web-based surveys were administered to a US sample of adult patients with asthma, and HCPs. Participants reviewed six vignettes describing two hypothetical patients with asthma (25-year-old/single/unemployed/ no dependents; and 45-year-old/married/employed/two young children) experiencing mild, moderate, or severe exacerbations and rated the impact on eight measures: EuroQoL-5 Dimensions (mobility, self-care, usual activities, pain/ discomfort, and anxiety/depression), sleep, household costs, and medical costs. The proportions reporting impact for each measure were calculated for each vignette; and patient responses were compared with HCP responses. Results: 302 patients with asthma and 300 HCPs completed the survey. As exacerbation severity increased, a higher proportion of patients and HCPs reported impact of exacerbations on patients with asthma. Compared with HCPs, a greater proportion of patients reported problems with pain/discomfort related to mild and moderate exacerbations. Compared with patients, HCPs were more likely to indicate sleep impact, mobility problems, and financial burden across all exacerbation severity levels; self-care problems with moderate and severe exacerbations; and problems with usual activities and anxiety/depression for severe exacerbations. Conclusions: Understanding the distinctions between how patients and HCPs perceive the impact of exacerbations is important for optimizing patient care. HCPs may be less aware of patient’s concerns about exacerbation-related pain/ discomfort. Studies are needed to further understand patient-HCP interactions regarding asthma-related exacerbations.

scholarly journals Impact of COVID-19 Pandemic on Ambulatory and Operating Room Rhinology Practice in the US

2020 ◽  
pp. 194589242096196
Author(s):  
P Papagiannopoulos ◽  
A Ganti ◽  
YJ Kim ◽  
RA Raad ◽  
EC Kuan ◽  
...  
Keyword(s):  
Medical Center ◽  
Point Of Care ◽  
The United States ◽  
Further Education ◽  
The Novel ◽  
Web Based ◽  
Number Of Patients ◽  
The Us ◽  
Novel Coronavirus ◽  
The Impact

Introduction The pandemic caused by the novel coronavirus virus has altered all facets of clinical practice in the United States. The goal of this study is to better understand the impact of COVID-19 on rhinologic ambulatory and operative practice. Methods A 27-item survey to assess these objectives was created and approved by the Division of Rhinology faculty at Rush University Medical Center in April 2020. The survey was then distributed to rhinologists in a web based format via www.surveymonkey.com from April 10 through April 23, 2020. Results A total of 277 U.S based rhinologists responded to the survey (23.04%). The most common practice types were single specialty private (44.9%) and academic (24.6%). 90.2% practice in a state under a shelter in place order. Comparing pre-COVID baseline to during-COVID, there was statistically significant reduction in the number of patients of seen daily in clinic ( p < 0.001). The number of nasal endoscopies in the office and surgical procedures fell dramatically. Overall, 5 respondent rhinologists have been infected with COVID-19 and 27 have been furloughed. Conclusion COVID-19 has drastically affected rhinologic practice. There is a dramatic reduction of in person care in the office setting and surgical management of sinonasal and skull base disease. Enhanced PPE is being used in only half of potentially aerosolizing procedures which represents an area of further education. Novel approaches such as use of virtual encounters and point of care testing should be considered as options to facilitate care.

Impact of COVID-19 on Nuclear Medicine in Germany, Austria and Switzerland: An International Survey in April 2020

2020 ◽  
Vol 59 (04) ◽  
pp. 294-299 ◽  
Author(s):  
Lutz S. Freudenberg ◽  
Ulf Dittmer ◽  
Ken Herrmann
Keyword(s):  
Nuclear Medicine ◽  
Health Systems ◽  
Personal Protective Equipment ◽  
Large Scale ◽  
Diagnostic Procedures ◽  
Protective Equipment ◽  
Current Crisis ◽  
Web Based ◽  
Public Versus Private ◽  
The Impact

Abstract Introduction Preparations of health systems to accommodate large number of severely ill COVID-19 patients in March/April 2020 has a significant impact on nuclear medicine departments. Materials and Methods A web-based questionnaire was designed to differentiate the impact of the pandemic on inpatient and outpatient nuclear medicine operations and on public versus private health systems, respectively. Questions were addressing the following issues: impact on nuclear medicine diagnostics and therapy, use of recommendations, personal protective equipment, and organizational adaptations. The survey was available for 6 days and closed on April 20, 2020. Results 113 complete responses were recorded. Nearly all participants (97 %) report a decline of nuclear medicine diagnostic procedures. The mean reduction in the last three weeks for PET/CT, scintigraphies of bone, myocardium, lung thyroid, sentinel lymph-node are –14.4 %, –47.2 %, –47.5 %, –40.7 %, –58.4 %, and –25.2 % respectively. Furthermore, 76 % of the participants report a reduction in therapies especially for benign thyroid disease (-41.8 %) and radiosynoviorthesis (–53.8 %) while tumor therapies remained mainly stable. 48 % of the participants report a shortage of personal protective equipment. Conclusions Nuclear medicine services are notably reduced 3 weeks after the SARS-CoV-2 pandemic reached Germany, Austria and Switzerland on a large scale. We must be aware that the current crisis will also have a significant economic impact on the healthcare system. As the survey cannot adapt to daily dynamic changes in priorities, it serves as a first snapshot requiring follow-up studies and comparisons with other countries and regions.

The Role of Web Based Accounting Online System 2.0 as the Company's Income and Expense Management

2017 ◽  
Vol 1 (1) ◽  
pp. 44-49
Author(s):  
Nur Azizah ◽  
Dedeh Supriyanti ◽  
Siti Fairuz Aminah Mustapha ◽  
Holly Yang
Keyword(s):  
Financial Management ◽  
Accounting System ◽  
Bank Account ◽  
Web Based ◽  
Online System ◽  
Version 2.0 ◽  
User Friendly ◽  
The Impact ◽  
A Company

In a company, the process of income and expense of money must have a profit-generating goal base. The success of financial management within the company, can be monitored from the ability of the financial management in managing the finances and utilize all the opportunities that exist with as much as possible with the aim to control the company's cash (cash flow) and the impact of generating profits in accordance with expectations. With a web-based online accounting system version 2.0, companies can be given the ease to manage money in and out of the company's cash. It has a user friendly system with navigation that makes it easy for the financial management to use it. Starting from the creation of a company's cash account used as a cash account and corporate bank account on the system, deletion or filing of cash accounts, up to the transfer invoice creation feature, receive and send money. Thus, this system is very effective and efficient in the management of income and corporate cash disbursements.   Keywords:​Accounting Online System, Financial Management, Cash and Bank

DAMPAK PROGRAM DIKLAT ONLINE TIK GURU PUSTEKKOM TERHADAP AKSESBILITAS KONTEN PEMBELAJARAN PADA FITUR RUMAH BELAJAR

2018 ◽  
Vol 19 (2) ◽  
pp. 84
Author(s):  
Eni Susilawati
Keyword(s):  
Teacher Training ◽  
Quantitative Research ◽  
Online Training ◽  
Research Approach ◽  
Intensity Level ◽  
Web Based ◽  
Learning Content ◽  
Open Questions ◽  
Ict Training ◽  
The Impact

The research objective is to analyze the impact of the participation of online  ICT teacher training to increase the number of accessibility the learning content of features in Rumah Belajar. This research used the quantitative research approach with descriptive quantitative analysis methods to be able to describe how the increase in accessibility features of Rumah Belajar and utilization in learning in school. Samples were selected in this study are all online training participants at 15 locations online training that has been conducted by Pustekkom in 2015 and 2016 in 2015. The data was collected using a questionnaire and a list of open questions in accordance with the purpose of research. The results showed that 1) online ICT teacher training participants, after completing the Pustekkom  training online  using become more motivated to access other feature in Rumah Belajar; 2) The order of the percentage of the intensity level of accessibility to the other features of Rumah Belajar are: Sumber Belajar 23%, BSE 23%, Bank Soal 21%, Kelas Maya 13%, Lab Maya 6%, Karya Guru 4%, Wahana Jelajah Angkasa 4%, Peta Budaya 4% and Karya Komunitas 2%, and ICT training online using the application PKB Rumah Belajar can be used as a reference for efforts to develop a web-based learning applications, in particular for the development of Rumah belajar portal belongs Pustekkom Kemendikbud. Tujuan penelitian yaitu untuk menganalisis dampak keikutsertaan diklat online  TIK guru Belajar terhadap peningkatan jumlah aksebilitas konten pembelajaran pada fitur-fitur rumah belajar. Penelitian ini menggunakan pendekatan penelitian kuantitatif dengan metode analisis kuantitatif secara deskriptif untuk bisa menggambarkan bagaimana peningkatan aksesbilitas fitur-fitur rumah belajar dan pemanfaatannya dalam pembelajaran di sekolah. Sampel yang dipilih dalam penelitian ini adalah semua peserta diklat online  pada 15 lokasi diklat online yang telah dilaksanakan oleh Pustekkom pada tahun 2015 dan 2016. Pengumpulan data menggunakan kuesioner dan daftar pertanyaan terbuka sesuai dengan tujuan penelitian. Hasil penelitian menunjukkan bahwa 1) peserta diklat online TIK Guru, setelah mengikuti diklat online Pustekkom, menjadi lebih termotivasi untuk mengakses fitur-fitur lainnya dalam Rumah Belajar; 2) Urutan prosentase tingkat intensitas aksesbilitas terhadap fitur-fitur Rumbel selain Pengembangan Keprofesian berkelanjutan (PKB) adalah: Sumber Belajar 23%, Buku Sekolah Elektronik (BSE) 23%, Bank Soal 21%, Kelas Maya 13%, Lab Maya 6%, Karya Guru 4%, Wahana Jelajah Angkasa 4%, Peta Budaya 4% dan Karya Komunitas 2%; dan 3) diklat online TIK menggunakan aplikasi PKB. Rumah belajar bisa dijadikan referensi bagi upaya pengembangan aplikasi pembelajaran berbasis web, khususnya bagi pengembangan portal Rumah Belajar milik Pustekkom Kemendikbud.

Systematic review methodology for development: An example from microfinance

2018 ◽  
Vol 43 (1) ◽  
pp. 65-77 ◽  
Author(s):  
Carina Van Rooyen ◽  
Ruth Stewart ◽  
Thea De Wet
Keyword(s):  
Systematic Review ◽  
International Development ◽  
Health Sector ◽  
Evidence Based ◽  
Systematic Review Methodology ◽  
Development Interventions ◽  
The Us ◽  
Sub Saharan ◽  
The Impact ◽  
Evidence Based Decision Making

Big international development donors such as the UK’s Department for International Development and USAID have recently started using systematic review as a methodology to assess the effectiveness of various development interventions to help them decide what is the ‘best’ intervention to spend money on. Such an approach to evidence-based decision-making has long been practiced in the health sector in the US, UK, and elsewhere but it is relatively new in the development field. In this article we use the case of a systematic review of the impact of microfinance on the poor in sub-Saharan African to indicate how systematic review as a methodology can be used to assess the impact of specific development interventions.

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