scholarly journals Nutritional Value of Lime and Lemon in Hypercholesterolaemic Induced Rats

2013 ◽  
Vol 3 (1) ◽  
pp. 13-16
Author(s):  
Anslem O Ajugwo ◽  
Tosan Erhabor ◽  
Tom Mokogwu ◽  
Kester Digban ◽  
Godwin Ojieh ◽  
...  
Keyword(s):  
Body Weight ◽  
Cholesterol Level ◽  
Nutritional Value ◽  
Egg Yolk ◽  
Blood Cholesterol ◽  
Control Group ◽  
Albino Rats ◽  
Blood Cholesterol Level ◽  
Medical Sciences ◽  
State Water

OBJECTIVE: People generally use lime and lemon when weight reduction is anticipated. This work was carried out to determine the effect of these fruits in hypercholesterolaemic induced rats. MATERIALS AND METHOD: Sixteen (16) albino rats were used and grouped into four groups of four (4) each. The rats were allowed to acclimatize and fed with egg yolk for seven days to induce hypercholesterolaemic state. Water, lemon, lime and lime+lemon were administered to these groups respectively. Cholesterol level was analyzed in all the groups after two (2) weeks of the administration of the fruits. RESULTS: The result showed a statistical decrease in the groups treated with lime, lemon and lime+lemon. The lime+lemon group showed a more significant decrease (p<0.05) in both cholesterol level and body weight when compared with the control group and other groups. This reduction may be as a result of the contents of the fruits. CONCLUSION: It can therefore be concluded that lime and lemon helps in the lowering of blood cholesterol level and body weight. DOI: http://dx.doi.org/10.3126/ajms.v3i1.5450 Asian Journal of Medical Sciences 3(2012) 13-16

Effect of feeding synbiotic products on the serum cholesterol, HDL cholesterol and non- HDL cholesterol level of albino rats

2018 ◽  
Author(s):  
Rakesh Kumar ◽  
Binita Rani ◽  
Sonia Kumari ◽  
A K Jha
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Serum Cholesterol ◽  
Total Cholesterol Level ◽  
Hdl Cholesterol ◽  
Blood Cholesterol ◽  
Control Group ◽  
Albino Rats ◽  
Therapeutic Benefits ◽  
Effect Of Feeding

Considering the excellent bio-therapeutic benefits of Lactobacillus and Bifidobacterium, this study exploited the probiotic characteristics of Lactobacillus acidophilus-015, Lactobacillus casei-297 and Bifidobacterium bifidum-229 strains with natural prebiotic substances viz. banana powder, malto-dextrin and honey to produce synbiotic food formulations and to study the effect of feeding their on the cholesterol level (mg/dl) of albino rats. On the basis of the preliminary investigation, synbiotic products with 2% banana powder, with 2% malto-dextrin, with 3% honey and synbiotic product with 2% each of, banana powder and malto-dextrin and 1% of honey were selected for the investigation of the total cholesterol, HDL-cholesterol and non-HDL cholesterol. The products showed a significant decrease in total cholesterol level, however the control group receiving the cholesterol rich laboratory diet showed a significant increase (P LESS THEN 0.01) in the total cholesterol after 45 days of feeding. There was 25.81 to 45.05% reduction of serum cholesterol was observed in case of feeding synbiotic formulations. Increase in the HDL-cholesterol and decrease in the non-HDL cholesterol were also significant. Therefore, synbiotic formulation with all these three natural prebiotic have enhanced ability to decreased down the blood cholesterol level.

scholarly journals Pengaruh Pemberian Berbagai Olahan Telur terhadap Kadar Kolesterol Total Darah Mencit

2016 ◽  
Vol 5 (3) ◽  
Author(s):  
Putri Mira Magistri ◽  
Rismawati YaswiR ◽  
Yustini Alioes
Keyword(s):  
Body Weight ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Cholesterol Content ◽  
Blood Cholesterol ◽  
Blood Cholesterol Level ◽  
Total Blood ◽  
Cholesterol Levels ◽  
Randomized Design ◽  
Total Blood Cholesterol

AbstrakMasyarakat menggunakan berbagai cara pengolahan sebelum mengonsumsi telur yang dapat berpengaruh terhadap kadar zat gizi yang terkandung didalamnya, termasuk kadar kolesterol dalam telur yang juga akan mempengaruhi kadar kolesterol dalam darah. Tujuan penelitian ini adalah menentukan pengaruh pemberian berbagai olahan telur terhadap kadar kolesterol total darah mencit. Penelitian menggunakan 24 ekor mencit (Mus musculus) jantan albino umur 3 – 4 bulan dengan berat badan sekitar 30 – 40 gram. Jenis kandang yang digunakan adalah kandang kotak (box) sebanyak 24 unit dengan ukuran 28x30x20 cm. Metode yang digunakan ialah eksperimen dengan Rancangan Acak Lengkap (RAL) terdiri dari 6 unit perlakuan, yaitu unit perlakuan K (Kontrol), unit perlakuan A (telur mentah), unit perlakuan B (telur goreng), unit perlakuan C (telur rebus), unit perlakuan D (telur setengah matang) dan unit perlakuan E (telur asin). Dosis perlakuan adalah 1,56ml/20gram berat badan/mencit dan masing-masing perlakuan diulang 4 kali. Parameter yang diukur adalah kadar kolesterol total darah mencit. Hasil analisis keragaman menunjukan bahwa pemberian berbagai olahan telur memberikan pengaruh berbeda sangat nyata (P<0.01) terhadap kadar kolesterol total darah mencit. Berdasarkan hasil penelitian dapat disimpulkan bahwa rerata kadar kolesterol total darah mencit setelah diberikan berbagai olahan telur adalah telur mentah 106.96 mg/dl, telur goreng 143.53 mg/dl, telur rebus 194.50 mg/dl, telur setengah matang 180.91 mg/dl, dan telur asin 158.27 mg/dl.Kata kunci: olahan telur, kadar kolesterol total darah, mencit AbstractPeople use various methods of processing before consumption eggs which can affect the levels of nutrients contained in, including cholesterol content which can also affect the levels of total cholesterol in blood. The objective of this study was to determine the effect of giving a variety of processed egg on total cholesterol levels of mice. The experiment used 24 male albino mice (Mus nusculus) age 3 – 4 months old with 30 – 40 grams of body weight. The den used was 24 units of box with size of 28x30x20 cm. The experiment used Completely Randomized Design (CRD) consist of 6 treatment units which was K (control), A (raw egg), B (fried egg), C (boiled egg), D (soft-boiled egg), and E (salted egg). The dosage was  1.56 ml/20 grams of body weight/mice and 4 replication for each treatment units. The parameter measured was total blood cholesterol level of mice.  Results of analysis of variance showed that giving of a variety of processed egg gave highly  significant  effect (P <0.01) on total blood cholesterol levels of mice. Based on the results of this study, it can be concluded that the average total blood cholesterol levels of mice after giving of various preparations of eggs is as follows: raw eggs 106.96 mg / dl, fried eggs 143.53 mg / dl, boiled eggs 194.50 mg / dl, soft-boiled eggs 180.91 mg / dl, and salted egg 158.27 mg / dl..Keywords: processed egg, total blood cholesterol level,  mice

scholarly journals The influence of aqueous extract of roselle (Hibiscus sabdariffa) calyx on blood cholesterol level and body weight in rats

2011 ◽  
Vol 9 (2) ◽  
pp. 43-49
Author(s):  
MEISA MARSALINA ◽  
SAMIGUN SAMIGUN ◽  
ENDANG SRI HARDJANTI
Keyword(s):  
Body Weight ◽  
Cholesterol Level ◽  
Aqueous Extract ◽  
Statistical Test ◽  
Blood Cholesterol ◽  
Average Weight ◽  
Hibiscus Sabdariffa ◽  
Blood Cholesterol Level ◽  
Significant Difference ◽  
One Way Anova

Marsalina M, Samigun, Hardjanti ES. 2011. The influence of aqueous extract of roselle (Hibiscus sabdariffa) calyx on blood cholesterol level and body weight in rats. Biofarmasi 9: 43-49. This study aimed to investigate the influence of aqueous extract of roselle calyx on blood cholesterol level and body weight in rats. This experimental research was arranged as a pre and post-test controlled group design. Thirty Sprague-Dawley rats, with 3 months of age and 250 g in average weight, were used as an animal model. Those rats were grouped equally into five groups, i.e. negative control (aquadest), positive control (0.26 mg lovastatin/200 g body weight of rats/2 mL), the first dose of aqueous extract of roselle calyx (65 mg/200 g/2 mL), the second dose of aqueous extract of roselle calyx (130 mg/200 g/2 mL), and the third dose of aqueous extract of roselle calyx (195 mg/200 g/2 mL). The measurement of rat blood cholesterol level was conducted before and after treatment, while the rat body weight was measured once a week. The result of this study was analyzed by using one-way ANOVA statistical test. The one-way ANOVA statistical test showed no significant difference on reducing blood cholesterol level with p=0.327 (p>0.05) and body weight in rat with p=0.154, p=0.214, and p=0.938 (p>0.05). This study concluded that the aqueous extract of roselle calyx has no influence on lowering blood cholesterol level and body weight in rats.

scholarly journals The effect of chocolate consumption (Theobroma cacao L.) on level of blood cholesterol and triglyceride in hypertension patients at Jatiroto Health Center, Indonesia

2019 ◽  
Vol 3 (1) ◽  
pp. 20
Author(s):  
Muzaroah Ermawati Ulkhasanah ◽  
Suharyo Hadisaputro ◽  
Rr. Sri Endang Pujiastuti
Keyword(s):  
Health Center ◽  
Cholesterol Level ◽  
Triglyceride Level ◽  
Intervention Group ◽  
Dark Chocolate ◽  
Blood Cholesterol ◽  
Control Group ◽  
P Value ◽  
Blood Cholesterol Level ◽  
Hypertensive Patients

Background: Hypertension is influenced by lifestyle factors such as high fat intake which has the potential for high blood cholesterol level. Cocoa products, which are rich sources of flavonoids, have been shown to reduce blood pressure and the risk of cardiovascular disease.Aims: The purpose of this research is to examine the dark chocolate consumption in decreasing the level of blood cholesterol and triglyceride in hypertension patients.Methods: This research is a quasi-experiment study with pre and post and control group design. There were thirty two (32) hypertensive patients selected from Jatiroto Health Center in June-July 2018 using a random sampling technique. The respondents were then divided to (1) a control group where patients were prescribed to a popular non-pharmacological therapy Simvastatin and (2) an intervention group where the respondents were prescribed with Simvastatin and also received an additional dark chocolate 60gr/day (given twice a day, each 30gr) for 15 days. A spectrophotometer glycerol phosphate oxidase (GPO-POD) with 546 nm wavelength was employed to measure the levels of blood cholesterol and triglyceride. The significant mean difference between pre and posttest, and the changes between control and intervention group were defined by statistical analysis T-test.Results: This study acknowledged that the prescribed simvastatin alone presents a significant contribution to decrease the cholesterol level at 14.40 point (p value = 0.041), however, the generic is not enough to deliver a significant effect to the decrease of triglyceride level in the hypertension patients (p value = 0.361). A great contribution to the depression of cholesterol and triglyceride level in the hypertensive respondent was observed if simvastatin prescription was combined with a provision of 60 gram dark chocolate, respectively to the level of 57.06 and 38.41 mg/dL with p value = 0.001. The addition of dark chocolate in the simvastatin prescription will significantly reduce the blood cholesterol level (p value = 0.020), but not really effective to reduce the triglyceride (p value = 0.560).Conclusion: The findings suggest that giving dark chocolate to the hypertensive patients who receive simvastatin prescription will decrease the cholesterol and triglyceride levels greater than the consumption of simvastatin drugs alone. Keywords: Dark chocolate, Simvastatin, Hypertension, Cholesterol, Triglyceride

scholarly journals THEINCREASE OFBLOOD CHOLESTEROL LEVELS IN WHITE RATS SUPPLEMENTED WITHCASSAVA YEAST

2021 ◽  
Vol 10 (1) ◽  
pp. 21-29
Author(s):  
Serly Nur Indah Permatasari ◽  
Samsuri Samsuri ◽  
Anak Agung Sagung Kendran
Keyword(s):  
Body Weight ◽  
Rattus Norvegicus ◽  
Statistical Tests ◽  
Blood Cholesterol ◽  
Control Group ◽  
Blood Cholesterol Level ◽  
Measuring Device ◽  
Blood Samples ◽  
Cholesterol Levels ◽  
White Rats

Tape yeast can be used as a source of genuine probiotics because tape yeast contain microbes such as molds, yeasts, and bacteria that are able to hydrolyze carbohydrates into glucose that are converted into alcohol. This study aimed to determine the effect of giving tape yeast for 21 days to the blood cholesterol levels of white rats(Rattus norvegicus). White rats were grouped into four treatments, namely P0: control; P1: under 100 mg/kg BW dose; P2: 200 mg/kg BW; and P3: 300 mg/kg BW of Tape yeast. The examination of blood cholesterol levels was tested by using EasyTouch GCU (Glucose, Cholesterol, and Uric Acid) with blue strips and chip tests. Blood samples were taken by cutting off tip of the tail and put the blood to the strip to see the results on the measuring device. The data obtained were analyzed by variancetest and data that were significantly different between treatments were continued with the Least Significance Different(LSD) test. The results of this study showed the average blood cholesterol level of treatment P1: 211.00 mg/dL, P2: 282.00 mg/dL and P3: 174.17 mg/dL higher than the control group P0: 149.67 mg/dL. Based on statistical tests were shown significantly different results on the treatment of P1 (100 mg/kg body weight), P2 (200 mg/kg body weight), and P3 (300 mg/kg body weight). Based on the result itcan be concluded the administration of tape yeast affects the blood cholesterol levels of white rats.

scholarly journals EFFECT OF PROBIOTIC AND PREBIOTIC CONSUMPTION ON BLOOD CHOLESTEROL LEVEL IN THE ELDERLY IN POSYANDU MANISJANGAN YOGYAKARTA

2021 ◽  
Vol 10 (3) ◽  
pp. 227-232
Author(s):  
Diyan Yunanto Setyaji ◽  
Fransisca Anjar Rina Setyani
Keyword(s):  
Cholesterol Level ◽  
Mung Bean ◽  
Lactobacillus Casei ◽  
The Elderly ◽  
Fermented Milk ◽  
Blood Cholesterol ◽  
Control Group ◽  
Blood Cholesterol Level ◽  
Cholesterol Levels ◽  
Lactobacillus Casei Shirota

Background: With advanced age, an increase in lipid profile is associated with the incidence of cardiovascular disease. Previous studies showed that the administration of probiotic and/or prebiotic are effective in improving lipid profiles. However, other studies have also shown that probiotic and prebiotic had insignificant effects on lipid profiles.Objectives: Determined the effects of probiotic and prebiotic on blood cholesterol level in the elderly.Methods: A total of 64 elderly who did not take cholesterol-lowering drugs enrolled in the quasi-experiment pretest-posttest design and were assigned to three interventions and control groups. The subjects in PRE-group consumed 100 grams of mung bean porridge per day; the subjects in PRO-group consumed 65 ml of fermented milk enriched with Lactobacillus casei Shirota strain per day; the subjects in PREPRO-group consumed 100 grams of mung bean porridge and 65 ml of fermented milk enriched with Lactobacillus casei Shirota strain per day. All intervention groups received treatment for 4 weeks. The control group did not receive any treatment during the study. Before and after treatment, cholesterol data was collected. Paired t-test, ANOVA, Post-hoc LSD were used for statistical analysis.Results There was an increase in cholesterol levels in PRE, PRO, PREPRO-groups (12.93 mg/dL; 48.37 mg/dL; and 7.62 mg/dL). Among the three intervention groups, only the consumption of probiotic was significant for changes in blood cholesterol levels (p 0.023). The administration of various interventions did not have a significant effect on changes in cholesterol levels (p 0.246) when compared to the control group.Conclusion: Prebiotic and probiotic do not lower blood cholesterol level in the elderly in Posyandu Manisjangan Yogyakarta.

scholarly journals Comparative evaluation of effect of green tea and green coffee on blood cholesterol level and body weight in albino rats

2018 ◽  
Vol 7 (10) ◽  
pp. 2053
Author(s):  
Ratan Kumar ◽  
Manoj Kumar Purty
Keyword(s):  
Cholesterol Level ◽  
Green Tea ◽  
Low Income ◽  
Treated Group ◽  
Overweight And Obesity ◽  
Blood Cholesterol ◽  
Chronic Medical Condition ◽  
Control Group ◽  
Albino Rats ◽  
Green Coffee

Background: Overweight and obesity are chronic medical condition responsible for risk factors for many non-communicable diseases. Development of rapid upsurge of these condition in medium and low-income group countries increased the awareness and uses of many types of remedies. Along with other natural herbal products green tea and green coffee have also became popular in communities. Aim of this study was to compare the effect of green tea and green coffee on blood cholesterol and weight in experimental animals.Methods: The experiment of this study was conducted in the Department of Pharmacology, MGM Medical college, Jamshedpur after ethical approval. 24 albino rats were selected and divided randomly in four groups A B C D. Group ‘A’ was kept as control group, group ‘B’ was given fat rich diet to produce hypercholesterolemia, group ‘C’ and ‘D’ were given green tea and green coffee respectively along with cholesterol rich diet. Weight and cholesterol level of rats were measured on 1st day, 2nd week and 4th week.Results: There was significant increase in serum cholesterol in non-treated animals as compared to control group but parameter showed significant less rise of cholesterol and weight in treated group by both green tea and green coffee than non-treated group. The comparative effect of green tea and green coffee had not much difference.Conclusions: This study has provided the information that natural products like green tea and green coffee are useful and helpful in preventive therapy of dyslipidemia and obesity.

scholarly journals Effect of bitter melon and garlic on blood glucose level and blood cholesterol level in rats in diabetic condition

2018 ◽  
Vol 5 (3) ◽  
pp. 359-363 ◽  
Author(s):  
Rupaly Akhter ◽  
Imrul Hasan Rasel ◽  
Mohammad Saiful Islam
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Dose Rate ◽  
Cholesterol Level ◽  
Glucose Level ◽  
The Body ◽  
Blood Cholesterol ◽  
Bitter Melon ◽  
Blood Cholesterol Level

The aim of this research was designed to investigate the single and combine effect of bitter melon and garlic on blood glucose level and blood cholesterol level in rats in diabetic condition. In this study 60 rats (12 normal rats and 48 alloxan induced diabetic rats) was used for trials. The rats were divided into 5 groups for each trial, each containing 12 individuals as follows: First group was normal control (A), Second group was diabetic control (B), third group was alloxan with bitter melon treated (C). Group D was alloxan and Garlic treated and Group E was alloxan, bitter melon, garlic treated. Then alloxan injection was injected at the dose rate of 100mg/kg body weight intraperitoneally to each rate to induce diabetes in groups B, C, D and E. On 10th day blood glucose level, blood cholesterol level and the body weights were measured for the first time to ensure diabetic induction as well as hypercholesterolemia. Then all the rats of that group were kept for more 21 days for the treatment of hyperglycemia and hypercholesterolemia. During that period on Day 0, 7, 14 and 21st the body weight, blood cholesterol level and blood glucose level were measured. Aqueous extract of bitter melon and garlic were fed at a dose rate of 300mg/kg and 500 mg/kg body weight for 21 days in group C and D respectively and combine in group E. The blood sugar level and blood cholesterol level were reduced in bitter melon, garlic & combine treatment groups compare with untreated group. From these findings it is concluded that the combination of bitter melon and garlic can be used as anti-hyperglycemic and anti- hypercholesterolemic agent. Res. Agric., Livest. Fish.5(3): 359-363, December 2018

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