scholarly journals Neonatal hyperbilirubinaemia and its early outcome

1970 ◽  
Vol 31 (3) ◽  
pp. 17-20
Author(s):  
D. Nepal ◽  
D. Banstola ◽  
A. K. Dhakal ◽  
U. Mishra ◽  
C. Mahaseth
Keyword(s):  
Tertiary Care ◽  
Institute Of Medicine ◽  
Clinical Sepsis ◽  
Early Outcome ◽  
Paediatric Hospital ◽  
Study Results ◽  
Common Causes ◽  
Study Population ◽  
Near Term ◽  
Key Words Hyperbilirubinaemia

Introduction: Jaundice is an important cause of morbidity in the neonatal period, especially in the 1st week of life. our Objective of the study was to find out early outcome of babies admitted in Kanti Children Hospital with neonatal jaundice (NNJ) and its association with other co-morbidities. Methods: This is a retrospective study conducted in tertiary care paediatric hospital from 1st March to1st June 2009. Altogether 73 babies were included in the study. Results: Male babies outnumbered females (72.6% vs. 27.4%). Only 2.4% babies were near-term. Low birth weight (LBW) babies constituted 19.2% of the study population. Clinical sepsis as defined by WHO criteria was observed in 86.3% of babies. Nearly 50% of the babies had serum bilirubin of 15-19.9 mg/dl. Most of the babies (94.5%) improved with 5.5% of mortality. Conclusions: Hyperbilirubinaemia is one of the most common causes of hospital admission in our nursery and it is associated with various other clinical morbidities. Phototherapy is effective in most of the time, but exchange transfusion should also be carried out when phototherapy fails. Causes of hyperbilirubinaemia should be searched extensively especially to rule out haemolysis Key words: Hyperbilirubinaemia, kernicterus, neonates, phototherapy DOI: 10.3126/joim.v31i3.2990 Journal of Institute of Medicine, December, 2009; 31(3) 17-20

scholarly journals Clinico-Laboratory Profile and Immediate Outcomes of Hyperbilirubinemic Babies Admitted in Kanti Children Hospital

1970 ◽  
Vol 30 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Deepeshwara Nepal ◽  
Dinesh Banstola ◽  
Ajaya Kumar Khakal ◽  
Udbhabhat Mishra ◽  
Chandeshawar Maheseth
Keyword(s):  
Exchange Transfusion ◽  
Serum Bilirubin ◽  
Neonatal Period ◽  
Tertiary Care ◽  
Paediatric Hospital ◽  
Study Population ◽  
Laboratory Profile ◽  
Near Term ◽  
Key Words Hyperbilirubinemia ◽  
Rule Out

Introduction: Jaundice is an important problem in the neonatal period especially in the first week of life. Our objective of the study is to find out the immediate outcome of hyperbilirubinemic babies admitted in Kanti Children Hospital. Methodology: This is a retrospective study and carried out in tertiary care paediatric hospital. Results: Altogether 73 babies were enrolled in the study. Male babies outnumbered the female (72.6% vs. 27.4%).Only 2.4% babies were near-term. LBW babies constitute 19.2% of the study population.86.3% of babies also have clinical sepses as defined by WHO criteria. Almost half of the babies have mild hyperbilirubinemia (15-19.9 mg/dl). Most of the babies (94.5%) improved and the mortality was 5.5%. Conclusion: Healthy term babies with a serum bilirubin <17mg/dl should not be admitted for routinely as they do not need phototherapy. Phototherapy is effective in most of the time, but exchange transfusion should also be carried out when phototherapy fails. Causes of hyperbilirubinemia should be searched extensively especially to rule out haemolysis. Key words: hyperbilirubinemia, kernicterus, neonates, phototherapy DOI: 10.3126/jnps.v30i1.2457 Journal of Nepal Paediatric Society Vol.30(1) 2010 31-36

Hypophosphataemia at a large academic hospital in South Africa

2008 ◽  
Vol 61 (10) ◽  
pp. 1104-1107 ◽  
Author(s):  
M Hoffmann ◽  
A E Zemlin ◽  
W P Meyer ◽  
R T Erasmus
Keyword(s):  
South Africa ◽  
Intensive Care ◽  
Tertiary Care ◽  
Neoplastic Disease ◽  
Western Cape ◽  
Tertiary Care Centre ◽  
Refeeding Syndrome ◽  
Common Causes ◽  
Study Population ◽  
Patient Groups

Aim:The aim of this study was to determine the most common causes of hypophosphataemia (⩽0.5 mmol/l) in a hospital population in order to identify patient groups at risk of developing the condition.Methods:The study was conducted at Tygerberg Hospital, a tertiary care centre in the Western Cape, South Africa. All patients identified with a phosphate level ⩽0.5 mmol/l during an 18-month period were included in the study. Medical records of these patients were reviewed.Results:Of all the requests received for serum phosphate determination by the laboratory, 2% (861 out of 45 394 requests) were ⩽0.5 mmol/l. Thirty per cent (30%; n = 189) of the patients in the study population died during their hospital stay. Most (45%; n = 278) of the patients with low phosphate levels occurred in an intensive care setting, whereas 10% (n = 63) were most likely due to refeeding, and 6% (n = 35) had neoplastic disease. Sepsis was implicated as a contributing factor in 26% (n = 162).Conclusion:Severe hypophosphataemia is associated with a very high mortality (30%, n = 189). Patients with a high risk of developing hypophosphataemia include those in an intensive care unit (ICU), patients suffering from neoplastic diseases, possible refeeding syndrome and septic patients. Regular phosphate determination is recommended in these patients to facilitate early diagnosis of hypophosphataemia.

scholarly journals Study of clinical profile of dermatophytosis in a tertiary care center as per ECTODERM guidelines

2021 ◽  
Vol 12 (10) ◽  
pp. 92-96
Author(s):  
Shitij Goel ◽  
Shivam Dr ◽  
Azra Ferheen Chaudhary
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Family Members ◽  
Previous Treatment ◽  
Clinical Profile ◽  
Cross Sectional ◽  
Study Results ◽  
Common Skin ◽  
Study Population ◽  
Chronic Dermatophytosis

Background: Dermatophytic infections are one of the most common skin infections encountered by dermatologists. A recent increase in incidence has been seen over the last few years with substantial change in the clinical profile of patients. Recently a group of dermatology experts published Expert Consensus on The Management of Dermatophytosis in India (ECTODERM India). The group agreed upon various definitions with respect to current dermatophytosis epidemic as well as gave recommendations for investigations and management. Clinical profile of dermatophytosis was done in present study on the basis of definitions agreed upon by ECTODERM consensus group. Aims and Objective: To assess the clinical profile, prevalence and severity of dermatophytic infection in study population. Materials and Methods: Cross-sectional observational study was conducted at out-patient department of Dermatology in, Sharda hospital, Greater Noida. A total of 317 patients presenting with clinical diagnosis of dermatophytosis were included in the study. Results: A total of 317 patients were recruited in the study, out of which 213 were males (67.2%). The most common age group presenting with superficial dermatophytosis was 21-30 years. Majority of the patient presented with chronic dermatophytosis with duration more than 6 months (76.6%) while more than 3 lesions of tinea were observed in 76.6% cases. 191 patients (60%) had moderate to severe involvement with more than 3% of BSA involved. Family members presenting with similar complaints were seen in 39% cases. Majority of patients (76 %) studies had received previous treatment topical, systemic or both. 62 patients presented with recurrence of disease within 6 weeks of complete antifungal treatment (19.6%). Conclusion: Our study concludes that dermatophytosis still remain a challenging issue for dermatologists. Chronicity of infection, moderate to severe BSA involvement and involvement of family members in a good proportion of our study cases were the main findings of our study.

Identifying the etiological profile of children presented with hepatomegaly admitted to a tertiary care hospital

2020 ◽  
Author(s):  
Chau Duc Nguyen Huu
Keyword(s):  
Tertiary Care Hospital ◽  
Statistical Significance ◽  
Tertiary Care ◽  
Care Hospital ◽  
Age Group ◽  
Central Hospital ◽  
Hematological Disorders ◽  
Study Results ◽  
Common Causes ◽  
Congenital Biliary Atresia

Objectives: To identify the pattern and etiology of diseases in children presented hepatomegaly at Pediatrics Department in Hue Central Hospital, Vietnam. Material and Methods: The Present study was conducted to evaluate the possible etiology and clinical features of children presented with hepatomegaly. A total of 107 children, from one month to fifteen years of age with hepatomegaly admitted in the Pediatric Department of Hue Central Hospital, Vietnam from May 2018 to April 2019 were included in this study. Results: The most common causes of hepatomegaly were inflammation/infection of the liver (miscellaneous cause included), hematological diseases and congestion heart failure with the percentage of 50.5%; 27,1% and 12,1%; respectively. Among the hepatitis group, viral agents account for nearly 50.0%, of which the most common one was Cytomegalovirus accounting for nearly 30.0%. Distribution of causes by age group revealed most cases in 1 year-old or younger children was caused by inflammation (53.8%), and in the older than 1 year-old children were hematological disorders (47.3%) which has statistical significance (P<0.05). Conclusions: Our research observed that the most common causes of the group of ≤ 1 year old were hepatitis, followed by cardiovascular disease and biliary obstruction due to congenital biliary atresia, and in the older than 1 year group, hematological disorders was the most common.

scholarly journals Profile and pattern of obstructive jaundice cases from a tertiary care teaching hospital of Uttar Pradesh

2017 ◽  
Vol 4 (2) ◽  
pp. 743
Author(s):  
Ashok Kumar Gupta ◽  
Abhishek Singh ◽  
Shwetank Goel ◽  
Rakesh Tank
Keyword(s):  
Obstructive Jaundice ◽  
Tertiary Care ◽  
Uttar Pradesh ◽  
Madhya Pradesh ◽  
Modes Of Presentation ◽  
Benign Biliary Strictures ◽  
Common Causes ◽  
Study Population ◽  
One Year ◽  
Loss Of Appetite

Background: The common etiologies of obstructive jaundice have been reported to vary from one centre to another and from one individual to another. Only a very few studies have been conducted on this topic and none from the state of Madhya Pradesh, India. The present study was planned to study the profile and pattern of obstructive jaundice cases in the region of Madhya Pradesh, India.Methods: A retrospective cohort of patients with obstructive jaundice admitted to SRMS Institute of Medical Sciences, Bareilly, Uttar Pradesh, India during past one year i.e. January to December 2014 formed the study population. In this study, all the eligible patients positively diagnosed as extrahepatic obstructive jaundice were included in this study. Study tools were records of the patients such as information/records from MRD department and clinical case sheets.Results: Malignant causes (63.89%) were more frequent than benign causes (36.11%). More than 50% cases were in the age group of 55-75 years. Sex wise males outnumbered females. Among the malignant causes of obstructive jaundice, cancer head of pancreas (60.87%) and cholangiocarcinoma (17.39%) were common causes whereas among the benign causes of obstructive jaundice, choledocholithiasis (76.92%) and benign biliary strictures (15.38%) were common causes.Conclusions: Jaundice (91.67%), loss of appetite (77.78%) and pain abdomen (75%) were three most common modes of presentation of obstructive jaundice cases.

scholarly journals Early Outcome of Surgery in Pediatric Head Injury: Experience From a Tertiary Care Center in Eastern Nepal

2020 ◽  
Vol 42 (2) ◽  
pp. 16-20
Author(s):  
Babita Khanal ◽  
Prakash Kafle ◽  
Sandip K Singh ◽  
Sunil K Yadav ◽  
Bishomber Neupane ◽  
...  
Keyword(s):  
Brain Injury ◽  
Head Injury ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Early Outcome ◽  
Pediatric Head Injury ◽  
Study Population ◽  
The Mean ◽  
Pediatric Tbi

Introduction Head injuries among the pediatric age group remain an unwelcomed source of morbidity and mortality resulting from falls, motor vehicle accidents, assaults, and child abuse. Early identification and management of traumatic brain injury (TBI) are crucial in halting the progress of the primary insult and preventing or reducing secondary brain injury. The present study aims to investigate the major cause of pediatric TBI and analyze the early outcome and serve as a reference study from a tertiary care center in eastern Nepal. MethodsThis is a prospective cohort study conducted in the Department of Pediatric Medicine and Neurosurgery from February 2018 to January 2020. All the pediatric head injury cases that were managed surgically in the center were included in the study. Presenting Glasgow coma scale (GCS) was correlated with the Glasgow outcome scale (GOS). ResultsThe study population comprised of 65 patients fulfilling the study inclusion criteria. The mean age of the study population was 10.86±4.72 years, fall was the commonest mode of injury (52.3%), 50.8% had mild TBI, 43.1% had moderate TBI and 6.2% had severe TBI. Depressed skull fracture with underlying extradural hematoma (EDH) or contusion was the commonest pathological diagnosis seen in 30.8 % (20) cases. The mean duration of hospital stay was 2.6 days. The presenting GCS correlated well with the outcome. ConclusionThis study concluded that the timely management of pediatric TBI can prevent grave prognosis and the patients presenting GCS and the pupillary reaction has strong correlation with the outcome.

HEMATOLOGICAL STUDY OF MACROCYTIC ANEMIA: STUDY AT A TERTIARY CARE HOSPITAL

2021 ◽  
pp. 69-71
Author(s):  
Sonali Smita Xess ◽  
Vaishali Anand
Keyword(s):  
Megaloblastic Anemia ◽  
Tertiary Care ◽  
Macrocytic Anemia ◽  
Care Hospital ◽  
Biochemical Tests ◽  
Common Causes ◽  
History Of ◽  
Study Population ◽  
Medical Materials ◽  
Set Up

Introduction: Anemia is one of the most commonly diagnosed conditions in a health care set up. Iron deciency anemia is the predominant cause of anemia across countries and in both sexes (1,2) . Although, in approximately 2 to 4 % of patients, laboratory evidence of macrocytosis is found (3) .The cause of macrocytic anemia is classied into megaloblastic or non-megaloblastic (4). Common causes of macrocytosis are different by region and setting. The present study aims at studying patients admitted in Civil Hospital Ahmedabad during the study period with MCV value more than 100 fL and utilizing the clinical prole and other biochemical parameters to further classify anemia into Megaloblastic and NonMegaloblastic type. The study period is January 1, 2018 to July 31, 2019. Relevant medical Materials and Methods: history of the patients participating in the study was considered. MCV value was determined from complete hemogram which was performed using Automatic Hematological Analyser. Peripheral smear examination was done with slides stained in Giemsa stain. Biochemical tests were performed using Automated Biochemistry Analysers. The data obtained from the above was then utilized in establishing the incidence of various causes of macrocytic anemia in our study population. Result: Out of the total 325 patients 160 (49%) were found to have megaloblastic anemia and 128 patients (40%) were found to have non-megaloblastic anemia. In the remaining 37 (11%) patients, no cause of macrocytosis was identied. The etiologies of macrocytic anemia identied in the present study were Vitamin B12 deciency, hepatic dysfunction, hypothyroidism, renal dysfunction and accelerated erythropoiesis (due to hemolysis or blood loss). Conclusion: The most common cause of macrocytic anemia in our study population was found to be Megaloblastic anemia.

scholarly journals Relationship between trajectories of post-stroke disability and self-rated health (NeuroAdapt): protocol for a prospective observational study

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e049944
Author(s):  
Sarah K Schäfer ◽  
Robert Fleischmann ◽  
Bettina von Sarnowski ◽  
Dominic Bläsing ◽  
Agnes Flöel ◽  
...  
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Functional Health ◽  
Care Hospital ◽  
Duration Of Symptoms ◽  
Post Stroke ◽  
Self Rated Health ◽  
Modifying Factors ◽  
Study Results

IntroductionStroke is the leading neurological cause of adult long-term disability in Europe. Even though functional consequences directly related to neurological impairment are well studied, post-stroke trajectories of functional health according to the International Classification of Functioning, Disability and Health are poorly understood. Particularly, no study investigated the relationship between post-stroke trajectories of activities of daily living (ADL) and self-rated health (SRH). However, such knowledge is of major importance to identify patients at risk of unfavourable courses. This prospective observational study aims to investigate trajectories of ADL and SRH, and their modifying factors in the course of the first year after stroke.Methods and analysisThe study will consecutively enrol 300 patients admitted to a tertiary care hospital with acute ischaemic stroke or transient ischaemic attack (TIA; Age, Blood Pressure, Clinical Features, Duration of symptoms, Diabetes score ≥3). Patient inclusion is planned from May 2021 to September 2022. All participants will complete an interview assessing ADL, SRH, mental health, views on ageing and resilience-related concepts. Participants will be interviewed face-to-face 1–5 days post-stroke/TIA in the hospital; and will be followed up after 6 weeks, 3 months, 6 months and 12 months via telephone. The 12-month follow-up will also include a neurological assessment. Primary endpoints are ADL operationalised by modified Rankin Scale scores and SRH. Secondary outcomes are further measures of ADL, functional health, physical activity, falls and fatigue. Views on ageing, social support, resilience-related concepts, affect, frailty, illness perceptions and loneliness will be examined as modifying factors. Analyses will investigate the bidirectional relationship between SRH and ADL using bivariate latent change score models.Ethics and disseminationThe study has been approved by the institutional review board of the University Medicine Greifswald (Ref. BB 237/20). The results will be disseminated through scientific publications, conferences and media. Moreover, study results and potential implications will be discussed with patient representatives.Trial registration numberNCT04704635.

Trend of Hospital Admission and Outcome Study of Patients Admitted in a Neurology Unit at a Tertiary Care Neuroscience Hospital in Bangladesh

2018 ◽  
Vol 4 (2) ◽  
pp. 69-74
Author(s):  
Md Tauhidul Islam Chowdhury ◽  
Mohammad Shah Jahirul Hoque Choudhury ◽  
KM Ahasan Ahmed ◽  
Mohammad Sadekur Rahman Sarkar ◽  
Md Abdullah Yusuf ◽  
...  
Keyword(s):  
Neurological Disorders ◽  
Neurological Diseases ◽  
Tertiary Care ◽  
Length Of Hospital Stay ◽  
Retrospective Chart Review ◽  
Total Death ◽  
Neurological Patients ◽  
Study Population ◽  
The Mean ◽  
Day By Day

Background: Neurological disorders is becoming a growing concern both for developed and developing countries. Magnitude of the problem is increasing day by day. Among all neurological disorders, stroke is the leading cause of morbidity and mortality globally.Objectives: The purpose of the study was to see the trend of admission of patients with neurological diseases and to study the outcome of patients at referral neurology hospital in Bangladesh.Methodology: This retrospective chart review was conducted in the blue unit of the Department of Neurology at National Institute of Neurosciences and Hospital, Dhaka, Bangladesh from 1st January to 31st December 2016 for a period of one (01) year. All the admitted patients with both sexes were selected as study population. The outcome was observed among the study population.Result: A total number of 1044 patients were admitted during the study period. Majority of the patients were in the age group of the 41 to 50 years which was 417(39.9%) cases. Both male and female were in highest number in the month of May which was 63 and 48 cases respectively. The total death of the study population was 146(14.0%) cases. The mean length of hospital stay was 8.4±2.31 days.Conclusion: Middle aged male is the main bulk of the neurological patients, admitted in a referral neurology hospital in Bangladesh. Highest admission and mortality was observed in stroke patients.Journal of National Institute of Neurosciences Bangladesh, 2018;4(2): 69-74

scholarly journals Accuracy of theoretical IOL formulas for Panoptix intraocular lens according to axial length

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ayoung Choi ◽  
Hyunggoo Kwon ◽  
Sohee Jeon
Keyword(s):  
Intraocular Lens ◽  
Axial Length ◽  
Mean Absolute Error ◽  
Visual Quality ◽  
Absolute Error ◽  
Fort Worth ◽  
Iol Implantation ◽  
Multifocal Iol ◽  
Study Results ◽  
Study Population

AbstractThe accuracy of intraocular lens (IOL) calculations is suboptimal for long or short eyes, which results in a low visual quality after multifocal IOL implantation. The purpose of the present study is to evaluate the accuracy of IOL formulas (Barrett Universal II, SRK/T, Holladay 1, Hoffer Q, and Haigis) for the Acrysof IQ Panoptix TFNT IOL (Alcon Laboratories, Inc, Fort Worth, Texas, United States) implantation based on the axial length (AXL) from a large cohort of 2018 cases and identify the factors that are associated with a high mean absolute error (MAE). The Barrett Universal II showed the lowest MAE in the normal AXL group (0.30 ± 0.23), whereas the Holladay 1 and Hoffer Q showed the lowest MAE in the short AXL group (0.32 ± 0.22 D and 0.32 ± 0.21 D, respectively). The Haigis showed the lowest MAE in the long AXL group (0.24 ± 0.19 D). The Barrett Universal II did not perform well in short AXL eyes with higher astigmatism (P = 0.013), wider white-to-white (WTW; P < 0.001), and shorter AXL (P = 0.016). Study results suggest that the Barrett Universal II performed best for the TFNT IOL in the overall study population, except for the eyes with short AXL, particularly when the eyes had higher astigmatism, wider WTW, and shorter AXL.

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