Hybrid diffusion tensor imaging feature-based AD classification

2020 ◽  
pp. 1-19
Author(s):  
Lan Deng ◽  
Yuanjun Wang

BACKGROUND: Effective detection of Alzheimer’s disease (AD) is still difficult in clinical practice. Therefore, establishment of AD detection model by means of machine learning is of great significance to assist AD diagnosis. OBJECTIVE: To investigate and test a new detection model aiming to help doctors diagnose AD more accurately. METHODS: Diffusion tensor images and the corresponding T1w images acquired from subjects (AD = 98, normal control (NC) = 100) are used to construct brain networks. Then, 9 types features (198×90×9 in total) are extracted from the 3D brain networks by a graph theory method. Features with low correction in both groups are selected through the Pearson correlation analysis. Finally, the selected features (198×33, 198×26, 198×30, 198×42, 198×36, 198×23, 198×29, 198×14, 198×25) are separately used into train 3 machine learning classifier based detection models in which 60% of study subjects are used for training, 20% for validation and 20% for testing. RESULTS: The best detection accuracy levels of 3 models are 90%, 98% and 90% with the corresponding sensitivity of 92%, 96%, and 72% and specificity of 88%, 100% and 94% when using a random forest classifier trained with the Shortest Path Length (SPL) features (198×14), a support vector machine trained with the Degree Centrality features (198×33), and a convolution neural network trained with SPL features, respectively. CONCLUSIONS: This study demonstrates that the new method and models not only improve the accuracy of detecting AD, but also avoid bias caused by the method of direct dimensionality reduction from high dimensional data.

2021 ◽  
Vol 11 (18) ◽  
pp. 8575
Author(s):  
Sudhir Kumar Mohapatra ◽  
Srinivas Prasad ◽  
Dwiti Krishna Bebarta ◽  
Tapan Kumar Das ◽  
Kathiravan Srinivasan ◽  
...  

Hate speech on social media may spread quickly through online users and subsequently, may even escalate into local vile violence and heinous crimes. This paper proposes a hate speech detection model by means of machine learning and text mining feature extraction techniques. In this study, the authors collected the hate speech of English-Odia code mixed data from a Facebook public page and manually organized them into three classes. In order to build binary and ternary datasets, the data are further converted into binary classes. The modeling of hate speech employs the combination of a machine learning algorithm and features extraction. Support vector machine (SVM), naïve Bayes (NB) and random forest (RF) models were trained using the whole dataset, with the extracted feature based on word unigram, bigram, trigram, combined n-grams, term frequency-inverse document frequency (TF-IDF), combined n-grams weighted by TF-IDF and word2vec for both the datasets. Using the two datasets, we developed two kinds of models with each feature—binary models and ternary models. The models based on SVM with word2vec achieved better performance than the NB and RF models for both the binary and ternary categories. The result reveals that the ternary models achieved less confusion between hate and non-hate speech than the binary models.


2020 ◽  
Author(s):  
Haochen Yao ◽  
Nan Zhang ◽  
Ruochi Zhang ◽  
Meiyu Duan ◽  
Tianqi Xie ◽  
...  

The recent outbreak of the coronavirus disease-2019 (COVID-19) caused serious challenges to the human society in China and across the world. COVID-19 induced pneumonia in human hosts and carried a highly inter-person contagiousness. The COVID-19 patients may carry severe symptoms, and some of them may even die of major organ failures. This study utilized the machine learning algorithms to build the COVID-19 severeness detection model. Support vector machine (SVM) demonstrated a promising detection accuracy after 32 features were detected to be significantly associated with the COVID-19 severeness. These 32 features were further screened for inter-feature redundancies. The final SVM model was trained using 28 features and achieved the overall accuracy 0.8148. This work may facilitate the risk estimation of whether the COVID-19 patients would develop the severe symptoms. The 28 COVID-19 severeness associated biomarkers may also be investigated for their underlining mechanisms how they were involved in the COVID-19 infections.


2021 ◽  
Vol 13 (15) ◽  
pp. 3024
Author(s):  
Huiqin Ma ◽  
Wenjiang Huang ◽  
Yingying Dong ◽  
Linyi Liu ◽  
Anting Guo

Fusarium head blight (FHB) is a major winter wheat disease in China. The accurate and timely detection of wheat FHB is vital to scientific field management. By combining three types of spectral features, namely, spectral bands (SBs), vegetation indices (VIs), and wavelet features (WFs), in this study, we explore the potential of using hyperspectral imagery obtained from an unmanned aerial vehicle (UAV), to detect wheat FHB. First, during the wheat filling period, two UAV-based hyperspectral images were acquired. SBs, VIs, and WFs that were sensitive to wheat FHB were extracted and optimized from the two images. Subsequently, a field-scale wheat FHB detection model was formulated, based on the optimal spectral feature combination of SBs, VIs, and WFs (SBs + VIs + WFs), using a support vector machine. Two commonly used data normalization algorithms were utilized before the construction of the model. The single WFs, and the spectral feature combination of optimal SBs and VIs (SBs + VIs), were respectively used to formulate models for comparison and testing. The results showed that the detection model based on the normalized SBs + VIs + WFs, using min–max normalization algorithm, achieved the highest R2 of 0.88 and the lowest RMSE of 2.68% among the three models. Our results suggest that UAV-based hyperspectral imaging technology is promising for the field-scale detection of wheat FHB. Combining traditional SBs and VIs with WFs can improve the detection accuracy of wheat FHB effectively.


2021 ◽  
Vol 15 (4) ◽  
pp. 18-30
Author(s):  
Om Prakash Samantray ◽  
Satya Narayan Tripathy

There are several malware detection techniques available that are based on a signature-based approach. This approach can detect known malware very effectively but sometimes may fail to detect unknown or zero-day attacks. In this article, the authors have proposed a malware detection model that uses operation codes of malicious and benign executables as the feature. The proposed model uses opcode extract and count (OPEC) algorithm to prepare the opcode feature vector for the experiment. Most relevant features are selected using extra tree classifier feature selection technique and then passed through several supervised learning algorithms like support vector machine, naive bayes, decision tree, random forest, logistic regression, and k-nearest neighbour to build classification models for malware detection. The proposed model has achieved a detection accuracy of 98.7%, which makes this model better than many of the similar works discussed in the literature.


2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi224-vi224
Author(s):  
Alexis Morell ◽  
Daniel Eichberg ◽  
Ashish Shah ◽  
Evan Luther ◽  
Victor Lu ◽  
...  

Abstract BACKGROUND Developing mapping tools that allow identification of traditional or non-traditional eloquent areas is necessary to minimize the risk of postoperative neurologic deficits. The objective of our study is to evaluate the use of a novel cloud-based platform that uses machine learning to identify cerebral networks in patients with brain tumors. METHODS We retrospectively included all adult patients who underwent surgery for brain tumor resection or thermal ablation at our Institution between the 16th of February and the 15th of May of 2021. Pre and postoperative contrast-enhanced MRI with T1-weighted and high-resolution Diffusion Tensor Imaging (DTI) sequences were uploaded into the Quicktome platform. After processing the data, we categorized the integrity of seven large-scale brain networks: sensorimotor, visual, ventral attention, central executive, default mode, dorsal attention and limbic. Affected networks were correlated with pre and postoperative clinical data, including neurologic deficits. RESULTS Thirty-five (35) patients were included in the study. The average age of the sample was 63.2 years, and 51.4% (n=18) were females. The most affected network was the central executive network (40%), followed by the dorsal attention and default mode networks (31.4%), while the least affected were the visual (11%) and ventral attention networks (17%). Patients with preoperative deficits showed a significantly higher number of altered networks before the surgery (p=0.021), compared to patients without deficits. In addition, we found that patients without neurologic deficits had an average of 2.06 large-scale networks affected, with 75% of them not being related to traditional eloquent areas as the sensorimotor, language or visual circuits. CONCLUSIONS The Quicktome platform is a practical tool that allows automatic visualization of large-scale brain networks in patients with brain tumors. Although further studies are needed, it may assist in the surgical management of traditional and non-traditional eloquent areas.


2018 ◽  
Vol 28 (02) ◽  
pp. 1750036 ◽  
Author(s):  
Shuqiang Wang ◽  
Yong Hu ◽  
Yanyan Shen ◽  
Hanxiong Li

In this study, we propose an automated framework that combines diffusion tensor imaging (DTI) metrics with machine learning algorithms to accurately classify control groups and groups with cervical spondylotic myelopathy (CSM) in the spinal cord. The comparison between selected voxel-based classification and mean value-based classification were performed. A support vector machine (SVM) classifier using a selected voxel-based dataset produced an accuracy of 95.73%, sensitivity of 93.41% and specificity of 98.64%. The efficacy of each index of diffusion for classification was also evaluated. Using the proposed approach, myelopathic areas in CSM are detected to provide an accurate reference to assist spine surgeons in surgical planning in complicated cases.


Transport ◽  
2020 ◽  
Vol 35 (5) ◽  
pp. 462-473
Author(s):  
Aleksandar Vorkapić ◽  
Radoslav Radonja ◽  
Karlo Babić ◽  
Sanda Martinčić-Ipšić

The aim of this article is to enhance performance monitoring of a two-stroke electronically controlled ship propulsion engine on the operating envelope. This is achieved by setting up a machine learning model capable of monitoring influential operating parameters and predicting the fuel consumption. Model is tested with different machine learning algorithms, namely linear regression, multilayer perceptron, Support Vector Machines (SVM) and Random Forests (RF). Upon verification of modelling framework and analysing the results in order to improve the prediction accuracy, the best algorithm is selected based on standard evaluation metrics, i.e. Root Mean Square Error (RMSE) and Relative Absolute Error (RAE). Experimental results show that, by taking an adequate combination and processing of relevant sensory data, SVM exhibit the lowest RMSE 7.1032 and RAE 0.5313%. RF achieve the lowest RMSE 22.6137 and RAE 3.8545% in a setting when minimal number of input variables is considered, i.e. cylinder indicated pressures and propulsion engine revolutions. Further, article deals with the detection of anomalies of operating parameters, which enables the evaluation of the propulsion engine condition and the early identification of failures and deterioration. Such a time-dependent, self-adopting anomaly detection model can be used for comparison with the initial condition recorded during the test and sea run or after survey and docking. Finally, we propose a unified model structure, incorporating fuel consumption prediction and anomaly detection model with on-board decision-making process regarding navigation and maintenance.


Author(s):  
Noor Asyikin Sulaiman ◽  
Md Pauzi Abdullah ◽  
Hayati Abdullah ◽  
Muhammad Noorazlan Shah Zainudin ◽  
Azdiana Md Yusop

Air conditioning system is a complex system and consumes the most energy in a building. Any fault in the system operation such as cooling tower fan faulty, compressor failure, damper stuck, etc. could lead to energy wastage and reduction in the system’s coefficient of performance (COP). Due to the complexity of the air conditioning system, detecting those faults is hard as it requires exhaustive inspections. This paper consists of two parts; i) to investigate the impact of different faults related to the air conditioning system on COP and ii) to analyse the performances of machine learning algorithms to classify those faults. Three supervised learning classifier models were developed, which were deep learning, support vector machine (SVM) and multi-layer perceptron (MLP). The performances of each classifier were investigated in terms of six different classes of faults. Results showed that different faults give different negative impacts on the COP. Also, the three supervised learning classifier models able to classify all faults for more than 94%, and MLP produced the highest accuracy and precision among all.


Author(s):  
Iqbal H. Sarker ◽  
Yoosef B. Abushark ◽  
Fawaz Alsolami ◽  
Asif Irshad Khan

Cyber security has recently received enormous attention in today’s security concerns, due to the popularity of the Internet-of-Things (IoT), the tremendous growth of computer networks, and the huge number of relevant applications. Thus, detecting various cyber-attacks or anomalies in a network and building an effective intrusion detection system that performs an essential role in today’s security is becoming more important. Artificial intelligence, particularly machine learning techniques, can be used for building such a data-driven intelligent intrusion detection system. In order to achieve this goal, in this paper, we present an Intrusion Detection Tree (“IntruDTree”) machine-learning-based security model that first takes into account the ranking of security features according to their importance and then build a tree-based generalized intrusion detection model based on the selected important features. This model is not only effective in terms of prediction accuracy for unseen test cases but also minimizes the computational complexity of the model by reducing the feature dimensions. Finally, the effectiveness of our IntruDTree model was examined by conducting experiments on cybersecurity datasets and computing the precision, recall, fscore, accuracy, and ROC values to evaluate. We also compare the outcome results of IntruDTree model with several traditional popular machine learning methods such as the naive Bayes classifier, logistic regression, support vector machines, and k-nearest neighbor, to analyze the effectiveness of the resulting security model.


2020 ◽  
Author(s):  
John T. Halloran ◽  
Gregor Urban ◽  
David Rocke ◽  
Pierre Baldi

AbstractSemi-supervised machine learning post-processors critically improve peptide identification of shot-gun proteomics data. Such post-processors accept the peptide-spectrum matches (PSMs) and feature vectors resulting from a database search, train a machine learning classifier, and recalibrate PSMs using the trained parameters, often yielding significantly more identified peptides across q-value thresholds. However, current state-of-the-art post-processors rely on shallow machine learning methods, such as support vector machines. In contrast, the powerful training capabilities of deep learning models have displayed superior performance to shallow models in an ever-growing number of other fields. In this work, we show that deep models significantly improve the recalibration of PSMs compared to the most accurate and widely-used post-processors, such as Percolator and PeptideProphet. Furthermore, we show that deep learning is able to adaptively analyze complex datasets and features for more accurate universal post-processing, leading to both improved Prosit analysis and markedly better recalibration of recently developed database-search functions.


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