scholarly journals Stabilitas Fisik Dan Antioksidan Mikroemulsi Minyak Nilam Dengan Variasi Tween 80 Dan PEG 400

Media Farmasi ◽  
2020 ◽  
Vol 16 (2) ◽  
pp. 185
Author(s):  
Ayu Shabrina ◽  
Annisa Rahayuning Pratiwi ◽  
Mimiek Muurukmihadi
Keyword(s):  
Antioxidant Activity ◽  
Physical Stability ◽  
Tween 80 ◽  
Test Method ◽  
Test Results ◽  
Climatic Chamber ◽  
Cycling Test ◽  
Peg 400 ◽  
Pogostemon Cablin ◽  
Dpph Method

Patchouli oil (Pogostemon cablin Benth.) has potential as an antioxidant and high volatility due to air and light, therefore it needs to be formulated in the form of a microemulsion. This research aims to determine the physical stability and antioxidant microemulsion of patchouli oil with different concentrations of Tween 80 and PEG 400. Microemulsions was prepared with patchouli oil content of 5% along with different concentration of Tween 80: PEG 400 were  F1 (26%: 13%), F2 (13%: 26%) and for F3 (26%: 26%). The patchouli oil microemulsion was tested for physical stability by the cycling test method using a climatic chamber at a temperature of 40 oC ± 2oC and 4 oC ± 2oC  for 6 cycles. Furthermore, the tests include organoleptic, homogeneity, viscosity, pH, and separation. The antioxidant test was carried out using the DPPH method, and the quantitative data on physical stability and antioxidants were analyzed by a t-dependent test. The stability test results showed that F2 and F3 had decreased viscosity after 6 storage cycles (p <0.05). The results of the homogeneity, pH and separation tests did not experience significant differences. The test results of patchouli oil microemulsion antioxidant activity showed no change in antioxidant activity during 6 storage cycles with the mean inhibition percent before and after the cycling test was  73,13 ± 0,38 %.  Patchouli oil microemulsion with tween 80: PEG 400 26%: 13% showed the most stable physical quality and antioxidant properties.Keywords : Microemulsion, Patchouli Oil, Physical Stability, AntioxidantsMinyak nilam (Pogostemon cablin Benth.) berpotensi sebagai antioksidan dan memiliki laju volatilitas tinggi akibat udara dan cahaya sehingga perlu diformulasikan dalam bentuk mikroemulsi. Penelitian ini bertujuan untuk mengetahui stabilitas fisik dan antioksidan mikroemulsi minyak nilam dengan variasi konsentrasi tween 80 dan PEG 400. Mikroemulsi dibuat dengan kadar minyak nilam 5% dan variasi konsentrasi campuran tween 80:PEG 400 adalah  untuk F1 (26%:13%) dan F2 (13%:26%) serta untuk F3 (26%:26%). Mikroemulsi minyak nilam diuji stabilitas fisik dengan metode cycling test menggunakan climatic chamber pada suhu 40 oC ± 2oC dan 4 oC ± 2oC selama 6 siklus. Pengujian meliputi organoleptis, homogenitas, viskositas, pH, dan uji pemisahan. Uji antioksidan dilakukan menggunakan metode DPPH. Data kuantitatif dari stabilitas fisik dan antioksidan dianalisis dengan uji t-dependent. Hasil uji stabilitas menunjukkan F2 dan F3 mengalami penurunan viskositas setelah 6 siklus penyimpanan (p < 0,05). Hasil uji homogenitas,pH dan uji pemisahan tidak mengalami perbedaan bermakna. Hasil uji aktivitas antioksidan mikroemulsi minyak nilam menunjukkan tidak terjadi perubahan aktivitas antioksidan selama 6 siklus penyimpanan dengan rerata persen inhibisi sebelum dan sesudah cycling test adalah 73,13 ± 0,38 %. Mikroemulsi minyak nilam F1 dengan tween 80: PEG 400 26%:13% menunjukkan Mutu fisik dan sifat antioksidan yang paling stabil.Kata kunci : Mikroemulsi, Minyak Nilam, Stabilitas Fisik, Antioksidan

scholarly journals FORMULASI DAN UJI EFEKTIVITAS ANTIOKSIDAN SEDIAAN KRIM EKSTRAK ETANOL DAUN BELIMBING WULUH (Averrhoa bilimbi L. ) DENGAN MENGGUNAKAN METODE DPPH (1,1-diphenyl-2-picrylhydrazyl)

PHARMACON ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 501
Author(s):  
Feiby Ariem ◽  
Paulina V.Y Yamlean ◽  
Julianri Sari Lebang
Keyword(s):  
Antioxidant Activity ◽  
Vitamin C ◽  
Ethanol Extract ◽  
Test Results ◽  
Cycling Test ◽  
A Value ◽  
Dpph Method ◽  
Before And After

ABSTRACTBelimbing wuluh leaves (Averrhoa bilimbi L.) Contains  flavonoids, phenols, alkaloids, tannins and coumarin. The aim of this research is formulated ethanol extract of Belimbing Wuluh leaves in the form of cream preparations, as well as test the effectiveness of antioxidants using the DPPH method. Extract was made by maceration method using ethanol 96% formulated into a cream with a concentration of 3%, 5%, 7%. The results of the cream preparations evaluation before and after cycling test meet the requirements of organoleptis, homogeneity, pH, adhesiveness, coverage. The test results of antioxidant activity with the DPPH method using the most effective UV-Vis spectrophotometer as the antioxidant cream of the leaves extract Belimbing Wuluh is 7% has a value of IC50 = 0.118 ppm and vitamin C as comparator has a value of IC50 = 0.0327 ppm. From this research can be concluded that Belimbing Wuluh leaves ethanol extract cream can be formulated as a stable cream and has a very strong antioxidant activity. Keywords: : Belimbing Wuluh Leaves,cream, antioxidant,DPPH ABSTRAK Daun Belimbing Wuluh (Averrhoa bilimbi L.)  mengandung senyawa flavonoid, fenol, alkaloid, tanin dan kumarin. Tujuan penelitian ini membuat formulasi ekstrak etanol daun Belimbing Wuluh dalam bentuk sediaan krim, serta menguji efektivitas antioksidan menggunakan metode DPPH. Pembuatan ekstrak dilakukan dengan metode maserasi menggunakan etanol 96 % diformulasi menjadi krim dengan konsentrasi 3%, 5% ,7%. Hasil evaluasi sediaan krim sebelum dan sesudah cycling test memenuhi persyaratan organoleptis, homogenitas, pH, daya lekat, daya sebar. Hasil uji aktivitas antioksidan dengan metode DPPH menggunakan spektrofotometer UV-Vis yang paling efektif sebagai krim antioksidan dari ekstrak daun Belimbing Wuluh adalah 7 % memiliki nilai IC50 = 0,118 ppm dan vitamin C sebagai pembanding memiliki nilai IC50 = 0,0327 ppm. Dari penelitian ini dapat disimpulkan bahwa krim ekstrak  etanol daun Belimbing Wuluh dapat diformulasikan sebagai sediaan krim yang stabil dan memiliki aktivitas antioksidan yang sangat kuat.  Kata kunci : Daun Belimbing Wuluh, Krim, Antioksidan, DPPH

Photostability Study on Character and Antioxidant Activity of Tomato Extract (Solanum lycopersicum l.) in Nanostructured Lipid Carrier (NLC) and Conventional Creame

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Noorma Rosita ◽  
Dewi Haryadi ◽  
Tristiana Erawati ◽  
Rossa Nanda ◽  
Widji Soeratri
Keyword(s):  
Antioxidant Activity ◽  
Physical Stability ◽  
Nanostructured Lipid Carrier ◽  
Uvb Radiation ◽  
K Value ◽  
Antioxidant Power ◽  
Solanum Lycopersicum L ◽  
Tomato Extract ◽  
Dpph Method ◽  
High Shear Homogenization

The aim of this study was to investigate the ability of NLC in increasing photostability of tomato extract in term of antioxidant activity. Photostability testing on antioxidant activity of samples were conducted by accelerating method using UVB radiation 32.400 joule for 21 hours radiation. Antioxidant activity was measured by DPPH method. NLC was made by High Shear Homogenization (HPH) method at 24000 rpm for 4 cycles, while conventional creame was made by low speed at 400 rpm. The product were characterized include: pH, viscosity, and particle size. There were had difference characters and physical stability. NLC had smaller size, more homogenous and more stable than conventional creame. It was known that stability of antioxidant activity of tomato extract in NLC system higher than in conventional creame. That was showed with k value, as constanta of rate scavenging activity decreasing in antioxidant power between time (Sigma 2-tail less than 0.005) of NLC and conventional creame were: 2.03x10-2 %/hour ±0.08 (3.94) and 4.71x 10-2 %/ hour ±0.23 (4.88) respectively.

scholarly journals Development, characterization and antioxidant activity of polysorbate based O/W emulsion containing polyphenols derived from Hippophae rhamnoides and Cassia fistula

2013 ◽  
Vol 49 (4) ◽  
pp. 763-773 ◽  
Author(s):  
Barkat Ali Khan ◽  
Naveed Akhtar ◽  
Haroon Khan ◽  
Valdir de Andrade Braga
Keyword(s):  
Antioxidant Activity ◽  
Ph Value ◽  
Antioxidant Activities ◽  
Physical Stability ◽  
Tween 80 ◽  
Ionic Surfactant ◽  
Cassia Fistula ◽  
Ph Values ◽  
Different Types ◽  
Electrical Conductivity Data

The objective of this study was to develop a pharmaceutical O/W emulsion containing plant-derived polyphenol extracts and evaluate its stability and antioxidant activity. O/W emulsions were prepared using ionic surfactant polysorbate 80 (Tween 80®). The odorwas adjusted with few drops of blue sea fragrance. DPPH (1,1-diphenyl-2-picrylhydrazyl) assay was used to evaluate the antioxidant activity of the plant extracts alone and emulsions containing these extracts. Physical stability was assessed by submitting the emulsions to storage at 8 ºC, 25 ºC, 40 ºC and 40 ºC + 70% RH (relative humidity) for two months. Various physical characteristics of emulsions monitored, include color, creaming, liquefaction, centrifugation and pH. Brookfield rotational rheometer was used to determined viscosities and rheological behavior of emulsions. Different types of emulsion were determined microscopically, while pH values of emulsions were measured by a pH meter. Electrical conductivity data confirmed that the outer phase was water. Samples presented an acceptable pH value for an external topical use. Shear thinning behaviour was observed for all emulsions. The polyphenol-rich-plant-derived extracts alone and the extract containing emulsions showed good antioxidant activities. This research confirmed that the method used was suitable for preparing emulsions with Hippophae rhamnoids and Cassia fistula extracts, suggesting that those emulsions are suitable for topical use.

scholarly journals PENGARUH WAKTU ULTRASONIKASI TERHADAP KARAKTERISTIK FISIKA NANOPARTIKEL KITOSAN EKSTRAK ETANOL DAUN SUJI (Pleomele angustifolia) DAN UJI STABILITAS FISIKA MENGGUNAKAN METODE CYCLING TEST

2019 ◽  
Vol 16 (02) ◽  
pp. 40
Author(s):  
Malinda Prihantini ◽  
Elya Zulfa ◽  
Listyana Dewi Prastiwi ◽  
Ikha Dyah Yulianti
Keyword(s):  
Particle Size ◽  
Zeta Potential ◽  
Physical Stability ◽  
Chitosan Nanoparticles ◽  
Ethanol Extract ◽  
Physical Characteristics ◽  
Test Method ◽  
Polydispersity Index ◽  
Cycling Test ◽  
Ultrasonication Time

ABSTRACT The nanoparticle system encapsulates and protects flavonoids of suji leaves from photolysis and oxidation instability. Chitosan is a biocompatible, biodegradable and non-toxic nanoparticles forming polymer. Ultrasonication is a materials mixing technique under high vibration energy. The ultrasonication time affects the particle size. The aim of this study was to determine the effect of the ultrasonication time on physical characteristics of chitosan nanoparticles of suji (Pleomele angustifolia) leaf ethanol extract and its physical stability after cycling test. Ethanol extract of suji leaves (EEDS) was obtained by maceration using 70% ethanol. Chitosan EEDS nanoparticles were made under ionic gelation method using an ultrasonication time of 3 minutes (FI), 6 minutes (FII), and 9 minutes (FIII). The physical characterization of nanoparticles includes particle size, polydispersity index, and zeta potential. Chitosan EEDS nanoparticles with the best physical characteristics (FIII) were tested for stability using cycling test method. The data obtained were analyzed using the Anova statistical method with a 95% confidence level. The size of EEDS chitosan nanoparticles (nm) was significantly different in all formulas, FI (374.47), FII (288.43), and FIII (233.37). The polydispersity index of FI (0.38) and FIII (0.65) were significantly different, while FII (0.41) was not significantly different. The zeta potential (mV) FI (51.70), FII (46.10), and FIII (48.60) were not significantly different in all formulas. The physical characteristics of Formula III after Cycling Test showed a particle size of 455.0 nm, a polydispersity index of 0.174, and a zeta potential of 20.1 mV. Keywords: ultrasonication, nanoparticles, chitosan, cycling test, suji leaf (Pleomele angustifolia)

scholarly journals EFFECT OF TRANSFERSOME FORMULATION ON THE STABILITY AND ANTIOXIDANT ACTIVITY OF N-ACETYLCYSTEINE IN ANTI-AGING CREAM

2020 ◽  
pp. 156-162
Author(s):  
HARMITA HARMITA ◽  
ISKANDARSYAH ISKANDARSYAH ◽  
SHOFIYAH FATIN AFIFAH
Keyword(s):  
Antioxidant Activity ◽  
Mobile Phase ◽  
Test Results ◽  
Penetration Test ◽  
Injection Volume ◽  
Accelerated Stability ◽  
Dpph Method ◽  
The Stability ◽  
Franz Diffusion Cells

Objective: N-acetylcysteine is an antioxidant with thiol/sulfhydryl groups and is currently being developed as an active ingredient in anti-agingcreams. The study’s aim was to compare the stability and antioxidant activity of N-acetylcysteine in anti-aging creams formulated with and withouta transfersome carrier system.Methods: Stability was assessed by performing cycling, centrifugal, and accelerated stability tests. In addition, antioxidant activity was measuredby the DPPH method, and in vitro penetration was measured using Franz diffusion cells. The analysis of N-acetylcysteine was performed using highperformanceliquid chromatography with ultraviolet–visible detection at a wavelength of 214 nm and a flow rate of 1.0 mL/min, injection volume of5 μL, and a mobile phase of phosphate buffer pH 3.0.Results: The N-acetylcysteine transfersome and non-transfersome cream preparations did not change color or show phase separation during thecycling and centrifugal tests. The N-acetylcysteine in the transfersome and non-transfersome cream preparations had strong antioxidant activity,with half-maximal inhibitory concentrations of 26.90 μg/mL and 38.63 μg/mL, respectively. The in vitro penetration test using Franz diffusion cellsshowed that the cumulative amount of penetrated N-acetylcysteine was 7355.13 μg/cm2 (flux of 845.67 μg/cm2∙h) in the transfersome cream and4677.61 μg/cm2 (flux of 533.33 μg/cm2∙h) in the non-transfersome cream.Conclusion: The in vitro penetration test results showed that the transfersome formulations in creams were able to increase the cumulative amountand flux of penetrated N-acetylcysteine in anti-aging cream preparations relative to those not formulated with transfersome.

scholarly journals UJI FITOKIMIA DAN PENENTUAN Inhibition Concentration 50% PADA BEBERAPA TUMBUHAN OBAT DI PULAU TIDORE

2014 ◽  
Vol 14 (2) ◽  
pp. 95
Author(s):  
Wiwin Abdullah ◽  
Max Revolta J. Runtuwene ◽  
Vanda Selvana Kamu
Keyword(s):  
Antioxidant Activity ◽  
Medicinal Plants ◽  
Leaf Extract ◽  
Ethanol Extract ◽  
Seed Extract ◽  
Test Results ◽  
Active Compounds ◽  
Inhibition Concentration ◽  
Dpph Method ◽  
Ic50 Values

ABSTRAK Penelitian ini dilakukan untuk mengetahui senyawa aktif yang terkandung melalui pengujian fitokimia dan aktivitas antioksidan pada tumbuhan obat di pulau Tidore. Uji aktivitas antioksidan menggunakan metode DPPH dilanjutkan dengan perhitungan Inhibition Concentration 50% (IC50). Hasil yang diperoleh adalah biji buah mojoi terkandung senyawa alkaloid dan saponin, buah coro terkandung alkaloid, flavonoid, dan saponin, pada daun ofo terkandung  alkaloid, tanin, flavonoid, steroid, dan saponin dan pada rimpang kuso mafola terkandung alkaloid, tanin, flavonoid, steroid, dan saponin. Nilai IC50 sebagai berikut biji rimpang kuso mafola 37,30 ppm, buah coro 250,17 ppm, daun ofo 976,10 ppm  dan buah mojoi 1001, 07 ppm. Kata kunci :Tumbuhan  obat, DPPH, antioksidan dan uji fitokimia. PHYTOCHEMICALS TEST AND DETERMINATION Inhibition Concentration 50% ON SOME MEDICINAL PLANTS IN THE TIDORE ISLAND ABSTRACT This study was conducted to determine the active compounds contained in an assessment of phytochemical and antioxidant activity in the medicinal plants of Tidore island. The test antioxidant activity was used DPPH method. In the test results to the phytochemical , that mojoi fruit seeds contained alkaloids and saponins, fruit coro (alkaloids, flavonoids, and saponins), ofo leaves (alkaloids, tannins, flavonoids, steroids, and saponins) and ethanol extract of rhizome kusomafola (alkaloids, tannins, flavonoids, steroids, and saponins. In  calculation of IC50 values ​​for rhizome kusomafola 37.30 ppm, 250.17 ppm coro fruit, 976.10 ppm ofo leaf extract, and fruit seed extract mojoi 1001.07 ppm. Keywords: Medicinal plants, DPPH, antioxidant and phytochemical test.

scholarly journals Aktivitas antioksidan krim kombinasi ekstrak Eucheuma Cottonii Sumbawa dan ekstrak Citrus lemon L. impor dengan metode DPPH

2019 ◽  
Vol 3 (1) ◽  
pp. 29
Author(s):  
Dwi Kurniawati Sambodo ◽  
Nandia Arlesia
Keyword(s):  
Antioxidant Activity ◽  
Negative Impact ◽  
Positive Control ◽  
Test Results ◽  
Negative Effects ◽  
High Exposure ◽  
Ic50 Value ◽  
Dpph Method ◽  
Qualitative Test ◽  
Eucheuma Cottonii

Cerrenty, The high exposure for free radicals has a negative impact on the health and aesthetics of the skin, especially facial skin, because it requires cosmetic that contain antioxidants to counteract and reduce the negative effects of it. Eucheuma cottonii and Citrus lemon L have bioactive compounds that have the potential as antioxidants. This research was conducted to find out antioxidant activity and the most optimal formula of the three cream formulas by DPPH method. Eucheuma cottonii and Citrus lemon L peel were extracted by remaseration method. The cream is formulated in 3 formulas with a ratio of extracts of 1: 2, 2: 1, and 1: 1 in 100 grams of cream with positive control of vitamin C. The three formulas were tested qualitatively and quantitatively by DPPH method with spectrophotometry visible at maximum wavelength 517 nm uses IC50 value. Qualitative test shown that the three cream formulas had antioxidant activity by DPPH damping which were characterized by reduced intensity of purple color. Quantitative test results in IC50 value formula 1 was 11251.5 ppm, formula 2 was 8592.2 ppm, and 10025.5 ppm for formula 3. From too  concluded that the three creams have antioxidant activity and formula 2 has the most optimal antioxidant than 2 other formulas

scholarly journals Uji Stabilitas Dan Aktivitas Antioksidan Mikroemulsi Likopen Tomat (Solanum lycopersicum L.)

2017 ◽  
Vol 3 (1) ◽  
pp. 10-17
Author(s):  
Evi Sulastri ◽  
Mohamad Ikram ◽  
Yuliet Yuliet
Keyword(s):  
Antioxidant Activity ◽  
Physical Stability ◽  
Tween 80 ◽  
Antioxidant Power ◽  
Solubility In Water ◽  
Solanum Lycopersicum L ◽  
Globule Size ◽  
Ic50 Value ◽  
Physical And Chemical

Lycopene is a class of keratonoid that have been proven has antioxidant activity but has limited solubility in water. So as to boost their solubility, in this study conducted in the form of microemulsion formulations. This study aims to get a tomato lycopene extract microemulsion which is stable and has antioxidant effects. The research was initiated to test the antioxidant power of tomato lycopene extract in vitro against DPPH. Tomato lycopene extract microemulsion is formulated based on the optimization of the composition of the base consisting of the VCO as the oil phase, tween 80 as surfactant and glycerin as cosurfactant. Preparations produced were tested for antioxidant activity and their physical and chemical stability testing which include: organoleptic, viscosity, globule size and pH during 28 days of storage. The results showed that tomato lycopene extract formula microemulsion stable composition of tomato lycopene extract 0.3%, VCO 15%, tween 80% and 35% glycerin. The test results obtained physical stability of the microemulsion formula elected tomato lycopene extract has a distinctive scent of aromatic, orange, thick, globule size of <5 μm, viscosity (600, 33 ± 69.29 to 746 cPs ± 8.32), and pH ( 6.27 ± 0.20 to 6.79 ± 0.10). As very strong antioxidant activity with IC50 value of 29.07 ppm.

scholarly journals PHYSICAL STABILITY AND ANTIOXIDANT ACTIVITY ASSAY OF A NANOEMULSION GEL FORMULATION CONTAINING TOCOTRIENOL

2017 ◽  
Vol 9 ◽  
pp. 140
Author(s):  
Mentari Mayang Suminar ◽  
Mahdi Jufri
Keyword(s):  
Antioxidant Activity ◽  
Room Temperature ◽  
Inhibitory Concentration ◽  
Physical Stability ◽  
Tween 80 ◽  
Skin Damage ◽  
Activity Assay ◽  
Nanoemulsion Gel ◽  
Different Temperatures ◽  
The Stability

Objective: Tocotrienols have an antioxidant potential higher than that of tocopherols. Nanoemulsion gel can deliver tocotrienols into the skin toprevent skin damage caused by free radicals and improve the stability of the dosage form. The present study aimed to determine the physical stabilityand antioxidant activity of a nanoemulsion gel formulation containing tocotrienol.Methods: The tocotrienol nanoemulsion was made using tocotrienols, oleic acid, Tween 80, 96% ethanol, and propylene glycol. The gel base was madeusing a carbomer and triethanolamine. A physical stability test was conducted at three different temperatures, namely, low temperature (4±2°C),room temperature (27±2°C), and high temperature (40±2°C). The antioxidant activity was measured using the 2,2-diphenyl-1-picrylhydrazyl methodfor determining inhibitory concentration (IC50) values.Results: Formula 1 demonstrated the best physical stability, with a pH of 6.2. The droplet size of the tocotrienol nanoemulsion gel was 596 nm, witha zeta potential value of −27.1 nm. The IC50 of the tocotrienol nanoemulsion gel was 6252.14 ppm.Conclusion: The nanoemulsion gel formulation retained antioxidant activity and was physically stable for 8 weeks.

scholarly journals Antioxidant in cosmeceutical products containing Calophyllum inophyllum oil

OCL ◽  
2021 ◽  
Vol 28 ◽  
pp. 28
Author(s):  
Charinrat Saechan ◽  
Jasadee Kaewsrichan ◽  
Nattawut Leelakanok ◽  
Arpa Petchsomrit
Keyword(s):  
Antioxidant Activity ◽  
Isopropyl Alcohol ◽  
Skin Diseases ◽  
Tween 80 ◽  
Gelling Agent ◽  
Total Phenolic ◽  
Stability Tests ◽  
Calophyllum Inophyllum ◽  
Dpph Method ◽  
Span 80

Every part of Calophyllum inophyllum L. has been used in various traditional remedies, especially the oil from its nut was mostly used to treat skin diseases. This study aimed to investigate the composition and antioxidant activity of C. inophyllum nut oil and formulate the oil as a cosmeceutical product. The chemical composition and the amount of total phenolic compounds (TPC) were demonstrated by Gas Chromatograph-Mass Spectrometer (GC-MS) and Folin–Ciocalteu method, respectively. Additionally, the antioxidant activity was tested using the DPPH method. Calophyllolide (4.35%) was a major component. Additional components were calanolide A, inophyllum D, and inophyllum B. We found that the TPC contained 25.9 ± 1.2 mg GE/g oil and a free radical scavenging activity approximate to that of the synthetic Trolox. Emulgel formulation consisted of tween 80, span 80, and isopropyl alcohol as a surfactant, and carbopol 940 as a gelling agent. The microemulsion was formulated using distilled water, oil, tween 80 with span 80, as a surfactant, and isopropyl alcohol as a cosurfactant. The mean droplet size for optimized microemulsion formulations was 34.37 ± 1.06 nm. Furthermore, the results of thermodynamic stability tests (freeze-thaw cycle) and long-term stability tests indicated that emulsions and microemulsions remained stable. In conclusion, this nut oil could potentially be used as a cosmeceutical product, and the obtained emulgels and microemulsions exhibited good characteristics in terms of being a potential agent for skin antioxidant.

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