scholarly journals Stimulation of embryonic and post-embryonic development of broilers using modern national immunomodulators

2019 ◽  
Vol 2019 (2) ◽  
pp. 37-44
Author(s):  
Александр Санин ◽  
Aleksandr Sanin ◽  
Анна Деева ◽  
Anna Deeva ◽  
Татьяна Кожевникова ◽  
...  
Keyword(s):  
Food Security ◽  
Embryonic Development ◽  
Growth And Development ◽  
Broiler Chickens ◽  
Antioxidant Effect ◽  
Immunomodulating Activity ◽  
Poultry Farmers ◽  
Anti Inflammatory ◽  
Stimulation Of

Much controversy exists concerning the problem of immunomodulators (IMD) usage in aviculture. We state that most reasonable way consists in the usage of IMD possessing not only immunomodulating activity, but some additional useful features as well: adjuvant, adaptogenic, anti-inflammatory, and antioxidative activities, stimulation of growth and development, etc. In this review special emphasis is made upon Phosprenyl and Gamavit, IMD which meet all of the above criteria. Moreover, use of these drugs poultry farmers literally begin ab ovo. We analyzed specific features of Phosprenyl and Gamavit usage both in the embryonic and postembryonic periods of broiler chickens breeding. An important advantage of these medicines is that, being classic IMD, they simultaneously possess the ability to enhance embryogenesis, growth and development of chickens, have antioxidant effect, stimulate hematopoiesis. All this makes it possible to widely use these drugs in industrial poultry, ensuring food security of our country.

scholarly journals Angiogenic Effect of Leptin in the Quail Chorioallantoic Membrane

2010 ◽  
Vol 79 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Pavel Výboh ◽  
Michal Zeman ◽  
Boris Bilčík ◽  
Božena Šárniková ◽  
Ľubor Košťál
Keyword(s):  
Embryonic Development ◽  
Growth And Development ◽  
Chorioallantoic Membrane ◽  
Nutrient Utilization ◽  
Avian Embryo ◽  
In Ovo ◽  
Angiogenic Effect ◽  
Vessel Development ◽  
Stimulation Of

Leptin, the product ofobgene, beside its key role in the control of body weight and food consumption, can be involved in the control of embryonic development. Leptin administrationin ovoaccelerated the embryonic and post-embryonic development in Japanese quail. Although the mechanisms of leptin effects on growth and development acceleration are not clear, stimulation of angiogenesis represents one of plausible explanations. Therefore, the aim of the present study was to investigate the pro-angiogenic effect of leptinin vivoin the quail chorioallantoic membrane (CAM). The recombinant murine leptin (10, 100, and 1000 ng) was applied eitherex ovoon the CAM surface ofex ovoincubated embryos at embryonic day 7 (ED7) orin ovointo the egg albumen at ED5. Changes in blood vessels were quantified by the fractal analysis providing the fractal dimension (Df) estimate. Leptin administeredin ovowas more efficient in stimulation of angiogenesis than theex ovotreatment, since 10 ng dose elicited significantly higher (P< 0.001) stimulation of vessel development of the CAM under the air cell than it did afterex ovocultivation. Our study confirmed that exogenously applied leptin was able to stimulate angiogenesis in CAM. Leptin-mediated stimulation of angiogenesis may improve nutrient utilization from the yolk and explain at least partially the accelerating effect of leptin on avian embryo growth and development.

Melatonin Modulates Lactation by Regulating Prolactin Secretion Via Tuberoinfundibular Dopaminergic Neurons in the Hypothalamus- Pituitary System

2020 ◽  
Vol 21 (8) ◽  
pp. 744-750 ◽  
Author(s):  
Hongyang Li ◽  
JingyaWei ◽  
Fengtao Ma ◽  
Qiang Shan ◽  
Duo Gao ◽  
...  
Keyword(s):  
Pineal Gland ◽  
Pituitary Gland ◽  
Antioxidant Capacity ◽  
Dopaminergic Neurons ◽  
Growth And Development ◽  
Endocrine System ◽  
Mammary Glands ◽  
Prolactin Secretion ◽  
The Body ◽  
Stimulation Of

In-depth studies have identified many hormones important for controlling mammary growth and maintaining lactation. One of these is melatonin, which is synthesized and secreted by the pineal gland to regulate circadian rhythms, improve antioxidant capacity, and enhance immunity. Prolactin is secreted by the pituitary gland and is associated with the growth and development of mammary glands as well as initiation and maintenance of lactation. The hypothalamus-pituitary system, the most important endocrine system in the body, regulates prolactin secretion mainly through dopamine released from tuberoinfundibular dopaminergic neurons. This review provides a reference for further study and describes the regulation of lactation and prolactin secretion by melatonin, primarily via the protection and stimulation of tuberoinfundibular dopaminergic neurons.

Chain-breaking/Preventive Antioxidant, Urate-lowering, and Anti-inflammatory Effects of Pure Curcumin

2020 ◽  
Vol 17 (1) ◽  
pp. 66-74
Author(s):  
Seghira Bisset ◽  
Widad Sobhi ◽  
Chawki Bensouici ◽  
Abdelhalim Khenchouche
Keyword(s):  
Uric Acid ◽  
Xanthine Oxidase ◽  
Acid Production ◽  
Biological Activities ◽  
Antioxidant Effect ◽  
Metal Chelating ◽  
Wide Range ◽  
Chain Breaking ◽  
Pharmaceutical Industries ◽  
Anti Inflammatory

Background: Several researches have shown that therapeutic compounds or phytochemicals from natural sources are important in the food as it is valuable in pharmaceutical industries due to their fewer side effects and potent against various diseases. Curcumin, a major polyphenol derived from turmeric spice, which used in many foods, has a wide range of biological activities, with quite a safety. Objective: The goal of this study was to investigate the antioxidant, urate-lowering, and antiinflammatory effects of pure curcumin. Methods: The antioxidant activity was evaluated for chain-breaking antioxidant effect (radicalscavenging and reducing abilities assays) and for preventive antioxidant effect with metal chelating assay, the urate-lowering was assayed on aspectrophotometer by measuring the inhibition of uric acid production by xanthine oxidase (XO) enzyme, and the anti-inflammatory effect was estimated using in vitro albumin denaturation inhibition. Results: Curcumin showed a significant and good chain-breaking antioxidant effect, both in free radical- scavenging assays (Galvinoxyl radical, ABTS, and hydroxyl radical), and in reducing abilities methods (reducing power, Cupric ion reducing antioxidant capacity and O-phenanthroline assays). In preventive antioxidant effect, assessed with the metal chelating assay, curcumin showed significant effect but with high concentration compared with standard. In the xanthine/xanthine oxidase system, curcumin significantly inhibited uric acid production (IC50=0.71 ± 0.06 mg/mL). Regarding antiinflammatory activity, curcumin showed significant inhibition of albumin denaturation with an IC50 value of 1181.69 ± 1.11μg/mL. Conclusion: These results indicated that curcumin showed promising antioxidant, anti-gout and antiinflammatory properties and might be used as potential, natural drugs against oxidative and inflammation- related diseases.

Maternal stevioside supplementation ameliorates intestinal mucosal damage and modulates gut microbiota in the chick offspring challenged with lipopolysaccharide

2021 ◽  
Author(s):  
Jingle Jiang ◽  
Lina Qi ◽  
Quanwei Wei ◽  
F. Shi
Keyword(s):  
Gut Microbiota ◽  
Broiler Chickens ◽  
Mucosal Damage ◽  
Anti Inflammatory ◽  
Antioxidant Effects

Our previous study showed that dietary stevioside supplementation could alleviate intestinal mucosal damage induced by lipopolysaccharide (LPS) through its anti-inflammatory and antioxidant effects in broiler chickens. However, it remains unknown...

scholarly journals Effects of Selected Prebiotics or Synbiotics Administered in ovo on Lymphocyte Subsets in Bursa of the Fabricius, Thymus, and Spleen in Non-Immunized and Immunized Chicken Broilers

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 476
Author(s):  
Marianna Szczypka ◽  
Agnieszka Suszko-Pawłowska ◽  
Maciej Kuczkowski ◽  
Michał Gorczykowski ◽  
Magdalena Lis ◽  
...  
Keyword(s):  
Immune System ◽  
Lactococcus Lactis ◽  
Blood Cells ◽  
Broiler Chickens ◽  
Lymphocyte Subsets ◽  
Double Positive ◽  
In Ovo ◽  
Lactococcus Lactis Subsp ◽  
Egg Incubation ◽  
Stimulation Of

The effects of in ovo-delivered prebiotics and synbiotics on the lymphocyte subsets of the lymphoid organs in non-immunized 7-day-old broiler chickens and in non-immunized, sheep red blood cells (SRBC)-immunized, and dextran (DEX)-immunized 21- and 35-day-old birds were studied. The substances were injected on the 12th day of egg incubation: Prebiotic1 group (Pre1) with a solution of inulin, Prebiotic2 group (Pre2) with a solution of Bi2tos (non-digestive transgalacto-oligosaccharides), Synbiotic1 group (Syn1) with inulin and Lactococcus lactis subsp. lactis IBB SL1, and Synbiotic2 group (Syn2) with Bi2tos and Lactococcus lactis subsp. cremoris IBB SC1. In 7-day-old chicks, a decrease in T splenocytes was noticed in all groups. The most pronounced effect in 21- and 35-day-old birds was an increase in TCRγδ+ cells in Syn1 and Syn2 groups. A decrease in bursal B cells was observed in DEX-immunized Pre1 group (21-day-old birds), and in the Syn1 group in non-immunized and SRBC-immunized 35-day-old birds. An increase in double-positive lymphocytes was observed in Pre1 (35-day-old birds) and Pre2 (immunized 21-day-old birds) groups. In Pre1 and Syn1 groups (21- and 35-day-old), an increase in B splenocytes and a decrease in T splenocytes were observed. We concluded that Syn1 was the most effective in the stimulation of the chicken immune system.

Pharmacological activities and Therapeutic potential of kaempferitrin in medicine for the treatment of human disorders: A review of medicinal importance and health benefits

2021 ◽  
Vol 21 ◽  
Author(s):  
Dinesh Kumar Patel
Keyword(s):  
Broiler Chickens ◽  
Therapeutic Potential ◽  
Scientific Information ◽  
Aloe Vera ◽  
Crocus Sativus ◽  
Related Complication ◽  
Food Material ◽  
Biological Potential ◽  
Anti Oxidant ◽  
Anti Inflammatory

Background: Herbal drugs and their derived phytochemicals are valuable for human being as a source of vital component of food material and drugs. Flavonoids are naturally occurring phytochemical produced in plants through metabolisms and they are having anti-hyperlipidemia, anti-inflammatory, anti-oxidant and anti-apoptotic activity. Flavonoids have been identified in the fruits, nuts, vegetables, seeds, stem, flowers and tea. Kaempferol is a natural flavonoidal compound present in edible plants such as apples, broccoli, strawberries, beans, grapefruit, propolis and medicinal plants such as Aloe vera, Ginkgo biloba, Rosmarinus officinalis, Crocus sativus L., Hypericum perforatum L. Kaempferol have anti-oxidant, anti-inflammatory, anti-apoptotic, pro-apoptotic, cardio-protective and anti-cancer activities. Methods: Glycosides of kaempferol such as kaempferitrin also called kaempferol 3,7-dirhamnoside are known to be more abundant than their flavonoid monomers in plants. Various literature databases have been searched to collect all the scientific information of kaempferitrin in the present investigation and analyzed in order to know the therapeutic benefit and biological potential of kaempferitrin. Moreover all the information has been presented here in two broad sections i.e. pharmacological and analytical. Results: From the analysis of all the collected and presented information, it was found that kaempferitrin has potent insulin-mimetic potential and could be used for the treatment of diabetes and related complication. However, it has also shown anti-oxidant, anti-inflammatory, anti-convulsant, anti-osteoporotic, anti-depressant, anthelmintic, immunostimulatory and natriuretic properties and inhibits cell proliferation and apoptosis. Kaempferitrin also improves meat quality of broiler chickens. Conclusions: The presented information in this work will be valuable to justify the biological importance and therapeutic potential of kaempferitrin in the scientific field.

scholarly journals Pengaruh Model Pendampingan Deteksi Dini Terhadap Kemampuan Guru PAUD Dalam Melaksanakan Deteksi Dini Pertumbuhan Dan Perkembangan Anak PAUD di Wilayah Puskesmas Beji Depok

2020 ◽  
Vol 11 (2) ◽  
pp. 94-100
Author(s):  
Suryati B ◽  
Bara Miradwiyana
Keyword(s):  
Early Childhood ◽  
Early Detection ◽  
Growth And Development ◽  
Intervention Group ◽  
Control Group ◽  
Childhood Growth ◽  
Childhood Education ◽  
Better Than ◽  
Stimulation Of ◽  
Mentoring Model

Impaired growth and development of children can be identified by early detection as prevention, prevention, stimulation and development. This study aims to determine the effect of early detection assistance models on the ability of early childhood education (PAUD) teachers in implementing early detection of early childhood growth and development. The research method uses pretest and posttest design with control group. Providing training and mentoring for PAUD teachers using the Stimulation of Detection and Early Intervention Growing Swell (SDIDTK)/ Child Development Pre-screening Questionnaire (KPSP) for the intervention group while for the control group for PAUD teachers by being given a KPSP booklet after the posttest. The results of the analysis showed that there were differences in scores of PAUD teachers' knowledge and skills in stimulating early childhood growth and development (p=0.001) between the intervention group and the control group after the mentoring model intervention. The knowledge of PAUD teachers who are given a mentoring model is better than the control group, there are significant differences in improving the ability of PAUD teachers to do early detection in children compared to the control group. PAUD teachers who are given the intervention of the mentoring model.

scholarly journals Pemberian Stimulasi Pertumbuhan dan perkembangan oleh Ibu Berhubungan Dengan Perkembangan Anak Usia 1-3 Tahun

2020 ◽  
Vol 11 ◽  
pp. 33
Author(s):  
Devi Nurhayati ◽  
Latifah Susilowati
Keyword(s):  
Child Development ◽  
Family Environment ◽  
Maternal Behavior ◽  
Growth And Development ◽  
Child Growth ◽  
P Value ◽  
Purposive Sampling ◽  
Mothers And Children ◽  
Spearman Test ◽  
Stimulation Of

Children entering the age of 1-3 years of development stage whose behavior starts to be influenced by the external environment and family environment that must provide good stimulation for children. Mother's behavior about stimulation is assessed as a basic need to hone child development and improve her abilities. The purpose of this study was determined the correlation between maternal behavior about growth and development stimulation with the development of children aged 1-3 years in Depok, Sleman, Yogyakarta. This study was used descriptive analytic method with cross sectional approach. 79 mothers and children taken by purposive sampling technique. Researchers collected data on respondents when mothers and children came to the posyandu. Respondents who were not present at the posyandu, the researchers collected data through home visits. The mother filled out a questionnaire about the mother's behavior in giving stimulation of child growth and development first, then the researcher conducted development using Denver II. The data collected was analyzed using the Spearman test. The most of mothers had good behavior in the stimulation of child growth and development that is 65 respondents (82.2%), and most of the children in the normal category are 58 respondents (73.4%). Based on Spearman's test the p value = 0.016 so that there is a relationship between maternal behavior about growth and development stimulation with child development, and the value of the closeness of a weak relationship is 0.269. There is a correlation between maternal behavior regarding growth and development stimulation with the development of children aged 1-3 years. Keywords: mother behavior; stimulation; growth and development; children aged 1-3 years ABSTRAK Orang tua terutama ibu harus memberikan stimulasi yang baik bagi anak. Perilaku ibu tentang stimulasi merupakan kebutuhan dasar untuk mengasah perkembangan anak dan meningkatkan kemampuannya. Tujuan dari penelitian untuk mengetahui hubungan perilaku ibu dalam pemberian stimulasi pertumbuhan dan perkembangan dengan perkembangan anak usia 1-3 tahun di Depok, Sleman. Sampel dalam penelitian ini berjumlah 79 ibu dan anak diambil dengan teknik purposive sampling. Peneliti melakukan pengambilan data pada responden saat ibu dan anak datang ke posyandu. Bagi calon responden yang tidak hadir pada saat posyandu maka peneliti melakukan pengambilan data melalui kunjungan rumah. Ibu mengisi kuesioner tentang perilaku ibu dalam pemberian stimulasi pertumbuhan dan perkembangan anak terlebih dahulu selanjutnya peneliti melakukan pemeriksaan pertumbuhan dan perkembangan pada anak menggunakan Denver II. Data dianalisis menggunakan uji Spearman. Sebagian besar Ibu memiliki perilaku baik dalam stimulasi pertumbuhan dan perkembangan anak yaitu 65 responden (82,3%) dan sebagian besar anak perkembangannya dalam kategori normal yaitu sebanyak 58 responden (73,4%). Berdasarkan uji Spearman hasil nilai p=0,016 sehingga ada hubungan antara perilaku ibu dalam pemberian stimulasi pertumbuhan dan perkembangan dengan perkembangan anak, dan nilai keeratan hubungan lemah yaitu 0,269. Ada hubungan antara perilaku ibu tentang stimulasi pertumbuhan dan perkembangan dengan perkembangan anak usia 1-3 tahun. Kata kunci: perilaku ibu; stimulasi; pertumbuhan dan perkembangan; anak usia 1-3 tahun

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