scholarly journals Role of Botanical Herbs Used in Covid-19 Treatment and Cure

2021 ◽  
Vol 4 (6) ◽  
pp. 291-298
Author(s):  
Kavita Chauhan ◽  
Amulya Gupta ◽  
Shruti Agrawal

Corona 2019 (COVID-19) is a new infectious disease caused by acute respiratory syndrome corona virus 2 (SARS-CoV-2) which belongs to the family of corona viruses. The first case appeared in December 2019, and the disease has transformed into a pandemic. Physical disability control is one of the main parts that play a role in its disease and leads to adverse effects for COVID-19 patients. At present, people believe taking herbal treatment that can stop COVID-19.  Medicinal plants can distribute as the therapeutic agents so it can help people to fight against the COVID-19 disease by boost their immunities. And such as, it can help to decrease the death rate that are linked with SARS-CoV-2 infections. So, in this analysis, we can make an effort to combine and talk about of different kind of traditional medicinal plants and their biological properties that can help to build-up our immune system and also play a biggest role in the fight against the viral infections including COVID-19. This document will help researchers and industry to recognize and assess in the making medicinal herb that can meet their needs in a variation of applications including herbal / ayurvedic antiviral products, anti-bacterial/antimicrobial design, immune-potentiator development, sanitization and sanitization programs.  

Author(s):  
Akshay Vaidya

Viral infections remain major “worldwide” cause of morbidity and mortality.  Herbal extracts or wholesome drugs have been in use for medicinal purposes since ancient time and are known for their antiviral properties and more tolerable side effects. Thus, naturally based pharmacotherapy is a proper alternative for treating viral diseases. Hence this article describes potential antiviral properties of medicinal plants against diverse group of viruses and suggests screening the potential of plants possessing broad spectrum anti-viral effects against viral diseases. Guduchyadi Kwath is a polyherb ayurvedic preparation useful in various diseases. It is useful in pitta vikar, shleshma vikar, Jwara, Chardi, Daha, Trushna, and Agnimandya1. According to modern science it showed anti-inflammatory, antioxidant, antibacterial, antiviral, antimalarial, hepatoprotective, wound healing and immune-modulatory action. The study is aim to the effect of “Guduchyadi kashaya” on viral diseases.


Author(s):  
Jean-Yves Chemin ◽  
Benoit Desjardins ◽  
Isabelle Gallagher ◽  
Emmanuel Grenier

The problem investigated in this part can be seen as a particular case of the study of the asymptotic behavior (when ε tends to 0) of solutions of systems of the type where Δε is a non-negative operator of order 2 possibly depending on ε, and A is a skew-symmetric operator. This framework contains of course a lot of problems including hyperbolic cases when Δε = 0. Let us notice that, formally, any element of the weak closure of the family (uε)ε>0 belongs to the kernel of A. We can distinguish from the beginning two types of problems depending on the nature of the initial data. The first case, known as the well-prepared case, is the case when the initial data belong to the kernel of A. The second case, known as the ill-prepared case, is the general case. In the well-prepared case, let us mention the pioneer paper by S. Klainerman and A. Majda about the incompressible limit for inviscid fluids. A lot of work has been done in this case. In the more specific case of rotating fluids, let us mention the work by T. Beale and A. Bourgeois and T. Colin and P. Fabrie. In the case of ill-prepared data, the nature of the domain plays a crucial role. The first result in this case was established in 1994 in the pioneering work by S. Schochet for periodic boundary conditions. In the context of general hyperbolic problems, he introduced the key concept of limiting system (see the definition on page 125). In the more specific case of viscous rotating fluids, E. Grenier proved in 1997 in Theorem 6.3, page 125, of this book. At this point, it is impossible not to mention the role of the inspiration played by the papers by J.-L. Joly, G. Métivier and J. Rauch (see for instance and). In spite of the fact that the corresponding theorems have been proved afterwards, the case of the whole space, the purpose of Chapter 5 of this book, appears to be simpler because of the dispersion phenomena.


Author(s):  
JYOTHI BASINI ◽  
SIREESHA RAYADURGAM ◽  
SWETHA DAKSHINAMURTHY

Nowadays, cancer is one of the most common diseases in humans. Among all types, colorectal cancer (CRC) is one of the most serious types diagnosed in men after lung and prostate cancer while in women it occupies the second position after breast cancer worldwide. The risk factors such as obesity, sedentary lifestyle, bad nutritional habits (high in fats and proteins), smoking, and progressive aging are the cause of CRC. The acquisition of abnormal mutations leads to a consisting of many different arrangements of events during the tumor development process. Over the years, different approaches have been employed, in the treatment of cancer. These include chemotherapy, radiotherapy, surgery, and immunotherapy. Chemotherapy is routinely used for cancer treatment, but the toxicity of chemotherapeutics on healthy cells of the human body is obvious. This is the reason for discovering the new, natural origin, substances with potential cytostatic effects and less toxic side effects on the healthy cells. Medicinal plants have a special place in the management of cancer. Numerous cancer research studies have been conducted using traditional medicinal plants to discover new therapeutic agents with fewer side effects. In this review, we are describing two medicinal plants such as Actiniopteris radiata (Sw.) Link (Mayurashikha) and Terminalia pallida Brandis (Tella karaka) (endemic plant) which are available immensely in Chittoor District are used till today by the traditional herbal practitioners, tribal people is near to Talakona forest and Ayurvedic people for various diseases and also for CRC.


2020 ◽  
Vol 21 (11) ◽  
Author(s):  
Esti Munawaroh ◽  
YUZAMMI YUZAMMI ◽  
Y. PURWANTO

Abstract. Munawaroh E, Yuzammi, Purwanto Y. 2020. The Euphorbiaceae (Spurge Family) in Bogor Botanic Gardens, Indonesia: Diversity, conservation and utilization. Biodiversitas 21: 5021-5031. Euphorbiaceae (Spurge family) is the fourth largest family world-wide, consists of 1,354 species and 91 genera. The family is also a part of the Bogor Botanic Gardens collections. The Gardens has evolved to fulfill its mission through five principal functions: conservation, research, education, tourism, and environmental services. The aims of this study are to reveal the diversity, conservation, and its potential in the Bogor Botanic Gardens. This research was based on direct observation of all members of Euphorbiaceae family in the Gardens, as well as Registration Unit and the Garden’s catalog which were observed for more than 10 years. The Gardens collected 39 genera, 71 species, and 136 specimens where 91 specimens are trees, 38 specimens are shrubs, three specimens are climbers and four specimens are succulents. Most of the collections are native to Indonesia 75.91% (103 specimens) and only 33 specimens (24.09%) from overseas. Amongst native collections have dominated from Jawa 25.54% (34 specimens), Sumatra 24.08% (33 specimens). The others are from Sulawesi 9.48% (13 specimens), Kalimantan 7.29% (10 specimens), Maluku 6.56% (9 specimens), Papua 2.28% (three specimens), and Nusa Tenggara Timur 0.72% (one specimen). Many species of the family have potentially developed as traditional medicinal plants (11 species), ornamental plants (16 species), spices and vegetable (two species), timbers (14 species), rubber plants (one species), source of energy (two species) and toxic (six species). Several old collections have retained at the Gardens that aged over 75 years, such as Mallotus philippensis (Lam.) Mull. Arg. forma mollis, Acalypha wilkesiana Mull. Arg., Acalypha hispida Burm. var. sanderi (N.E.Br.) J. J. Sm., Acalypha wilkesiana Mull. Arg. forma Montana, Sapium aucuparium Jacq. and Ricinodendron heudelotii (Bail.) Heckel. A map of planting point of the Euphorbiaceae collections is provided.


Author(s):  
Ramesh Verma ◽  
Vinod Chayal ◽  
Meenakshi Kalhan ◽  
Rohit Dhaka ◽  
Ginni Agrawal ◽  
...  

Coronavirus disease is caused by a novel virus belonging to the family of corona viruses similar to severe acute respiratory syndrome (SARS) and  name given to the novel virus as SARS Coronavirus- 2 (SARS-CoV-2) and the disease was named as COVID-19 on 11th February 2020 by World Health Organization (WHO). First case of this infection was reported in December 2019 in Wuhan city of China and after that it spread globally.3 On 30th January 2020, WHO declared this disease as Public Health Emergency of International Concern (PHEIC) and on 11th March 2020, WHO declared it as a pandemic when the infection was reported from all six WHO regions.


Pharmaceutics ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 1385
Author(s):  
Madira Coutlyne Manganyi ◽  
Gothusaone Simon Tlatsana ◽  
Given Thato Mokoroane ◽  
Keamogetswe Prudence Senna ◽  
John Frederick Mohaswa ◽  
...  

Drimia (synonym Urginea) plants are bulbous plants belonging to the family Asparagaceae (formerly the family Hyacinthaceae) and are distinctive, powerful medicinal plants. Just some species are indigenous to South Africa and have been traditionally utilized for centuries to cure various diseases and/or ailments. They have been recognized among the most famous and used medicinal plants in South Africa. Traditionally, the plants are used for various illnesses such as dropsy, respiratory disease, bone and joint complications, skin disorders, epilepsy and cancer. A number of studies have reported biological properties such as antiviral, antibacterial, antioxidant and anti-inflammatory, immunomodulatory, and anticancer activities. Their bulbs are a popular treatment for colds, measles, pneumonia, coughs, fever and headaches. However, some plant species are regarded as one of the six most common poisonous plants in Southern Africa that are toxic to livestock and humans. Due to the therapeutic effects of the Drimia plant bulb, research has focused on the phytochemicals of Drimia species. The principal constituents isolated from this genus are cardiac glycosides. In addition, phenolic compounds, phytosterols and other phytochemical constituents were identified. This study constitutes a critical review of Drimia species’ bioactive compounds, toxicology, biological properties and phytochemistry, advocating it as an important source for effective therapeutic medicine. For this purpose, various scientific electronic databases such as ScienceDirect, Scopus, Google Scholar, PubMed and Web of Science were researched and reviewed to conduct this study. Despite well-studied biological investigations, there is limited research on the toxic properties and the toxic compounds of certain Drimia species. Searching from 2017 to 2021, Google Scholar search tools retrieved 462 publications; however, only 3 investigated the toxicity and safety aspects of Drimia. The aim was to identify the current scientific research gap on Drimia species, hence highlighting a thin line between poisonous and healing compounds, dotted across numerous publications, in this review paper.


Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4535
Author(s):  
Lujain Eddin ◽  
Niraj Jha ◽  
M. F. Nagoor Meeran ◽  
Kavindra Kumar Kesari ◽  
Rami Beiram ◽  
...  

Limonene is a monoterpene confined to the family of Rutaceae, showing several biological properties such as antioxidant, anti-inflammatory, anticancer, antinociceptive and gastroprotective characteristics. Recently, there is notable interest in investigating the pharmacological effects of limonene in various chronic diseases due to its mitigating effect on oxidative stress and inflammation and regulating apoptotic cell death. There are several available studies demonstrating the neuroprotective role of limonene in neurodegenerative diseases, including Alzheimer’s disease, multiple sclerosis, epilepsy, anxiety, and stroke. The high abundance of limonene in nature, its safety profile, and various mechanisms of action make this monoterpene a favorable molecule to be developed as a nutraceutical for preventive purposes and as an alternative agent or adjuvant to modern therapeutic drugs in curbing the onset and progression of neurodegenerative diseases. This manuscript presents a comprehensive review of the available scientific literature discussing the pharmacological activities of limonene or plant products containing limonene which attribute to the protective and therapeutic ability in neurodegenerative disorders. This review has been compiled based on the existing published articles confined to limonene or limonene-containing natural products investigated for their neurotherapeutic or neuroprotective potential. All the articles available in English or the abstract in English were extracted from different databases that offer an access to diverse journals. These databases are PubMed, Scopus, Google Scholar, and Science Direct. Collectively, this review emphasizes the neuroprotective potential of limonene against neurodegenerative and other neuroinflammatory diseases. The available data are indicative of the nutritional use of products containing limonene and the pharmacological actions and mechanisms of limonene and may direct future preclinical and clinical studies for the development of limonene as an alternative or complementary phytomedicine. The pharmacophore can also provide a blueprint for further drug discovery using numerous drug discovery tools.


2021 ◽  
Vol 8 ◽  
pp. 204993612110630
Author(s):  
Kritika Srinivasan ◽  
Mana Rao

The coronavirus disease of 2019 (COVID-19) has caused significant morbidity and mortality among infected individuals across the world. High transmissibility rate of the causative virus – Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) – has led to immense strain and bottlenecking of the health care system. While noteworthy advances in vaccine development have been made amid the current global pandemic, most therapeutic agents are repurposed from use in other viral infections and are being evaluated for efficacy in COVID-19. Favipiravir, an orally administered drug originally developed in Japan against emerging influenza viral strains, has been shown to have widespread application and safety across multiple ribonucleic acid (RNA) viral infections. With a strong affinity toward the viral RNA-dependent RNA polymerase (RdRp), favipiravir could be a promising therapy against SARS-CoV-2, by targeting downstream viral RNA replication. Initial trials for usage in COVID-19 have suggested that favipiravir administration during initial infection stages, in individuals with mild to moderate infection, has a strong potential to improve clinical outcomes. However, additional well-designed clinical trials are required to closely examine ideal timing of drug administration, dosage, and duration, to assess the role of favipiravir in COVID-19 therapy. This review provides evidence-based insights and throws light on the current clinical trials examining the efficacy of favipiravir in tackling COVID-19, including its mechanism, pharmacodynamics, and pharmacokinetics.


2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Zineb Jalal ◽  
Meryem Bakour ◽  
Badiaa Lyoussi

The world is currently grappling with the coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The infection can cause fever, a dry cough, fatigue, severe pneumonia, respiratory distress syndrome, and in some cases death. There is currently no effective antiviral SARS-CoV-2 drug. To reduce the number of infections and deaths, it is critical to focus on strengthening immunity. This review aims to conduct a comprehensive search on the previous studies using Google Scholar, ScienceDirect, Medline, PubMed, and Scopus for the collection of research papers based on the role of zinc in the immune system, the antiviral activity of zinc, the effect of zinc supplementation in respiratory infections, the therapeutic approaches against viral infections based on medicinal plants, and the role of plants’ bioactive molecules in fighting viral infections. In conclusion, we highlighted the pivotal role of zinc in antiviral immunity and we suggested the bioactive molecules derived from medicinal plants as a search matrix for the development of anti-SARS-CoV-2 drugs.


2020 ◽  
Vol 20 (4) ◽  
pp. 156-161
Author(s):  
Lalbiakngheti Tlau ◽  
Lucy Lalawmpuii

Medicinal plants are the source of therapeutic agents in traditional medicines. The present study investigated Mizo traditional medicinal plants commonly used and available at N. Mualcheng, a village in Mizoram, India. The most important plants in terms of usage and availability as 10 species belonging to 9 families, of which Asteraceae contributes two species (such as Blumea lanceolaria, Acmella sp.), while Fabaceae, Acanthaceae, Costaceae, Orobanchaceae, Proteaceae, Elaeagnaceae, Smilacaceae and Plantaginaceae contribute one species each such as Mimosa pudica, Thunbergia grandiflora, Chamaecostus cuspidatus, Aeginetia indica, Helicia robusta, Elaeagnus caudata, Smilax perfoliata and Plantago asiatica respectively. An important feature of these medicinal plants is that some of them are used for complex diseases including kidney problem, gastric ulcer and diabetes mellitus.


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